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egtazic acid and 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one

egtazic acid has been researched along with 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (8.33)18.2507
2000's19 (79.17)29.6817
2010's3 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Bitar, KN; Ibitayo, AI; Nozu, F; Owyang, C; Tsunoda, Y1
Sagi-Eisenberg, R; Seger, R; Shefler, I1
English, D; Siddiqui, RA1
Guang, L; Kaziro, Y; Koide, H; Li, G; Suzuki, J; Yamazaki, Y1
Chien, CS; Chiu, CT; Hsiao, LD; Lin, CC; Shyr, MH; Wang, CC; Yang, CM1
Chang, LC; Wang, JP1
Comella, JX; Dolcet, X; Egea, J; Encinas, M; Espinet, C; Iglesias, M; Rocamora, N; Soler, RM; Yuste, VJ1
Chen, K; Keaney, JF; Thomas, SR1
Atkinson, BT; Pears, CJ; Stafford, MJ; Watson, SP1
Prasadarao, NV; Sukumaran, SK1
Bazan, NG; Bernatchez, PN; Gélinas, DS; Rollin, S; Sirois, MG1
Costa, M; Huang, C; Li, J; Shi, X; Tong, Q1
Costa, M; Huang, C; Li, J; Ouyang, W; Shi, X1
Burgos, RA; Carretta, D; Hancke, JL; Hidalgo, MA; Sandoval, A; Sanhueza, A; Triviños, F1
Alrefai, WA; Dudeja, PK; Gill, RK; Ramaswamy, K; Saksena, S; Tyagi, S1
Hanada, A; Hirano, K; Hirano, M; Kanaide, H; Momota, F; Nomoto, N1
Arshad, F; Braun, AP; Braun, JE; Sheng, JZ1
Albert, AP; Large, WA; Saleh, SN1
Alrefai, WA; Annaba, F; Dwivedi, A; Gill, RK; Saksena, S; Sarwar, Z1
Bae, SS; Choi, YW; Han, J; Kim, CD; Lee, YJ; Park, JY; Shin, HK1
Boffo, S; Caparrotti, G; Ciarcia, R; d'Angelo, D; Damiano, S; Florio, S; Giordano, A; Montagnaro, S; Morales, F; Pagnini, U; Rizzolio, F; Ruocco, A1
Hsieh, CW; Huang, YT; Wung, BS; Yang, PM; Zhang, YQ1
Ao, L; Cao, J; Cui, Z; Liu, J; Liu, T; Mo, M; Wang, X; Zhang, X1

Other Studies

24 other study(ies) available for egtazic acid and 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Src kinase and PI 3-kinase as a transduction pathway in ceramide-induced contraction of colonic smooth muscle.
    The American journal of physiology, 1998, Volume: 275, Issue:4

    Topics: Amino Acid Sequence; Androstadienes; Animals; Benzoquinones; Calcium; Chromones; Colon; Egtazic Acid; Enzyme Inhibitors; In Vitro Techniques; Kinetics; Lactams, Macrocyclic; Models, Biological; Molecular Sequence Data; Morpholines; Muscle Contraction; Muscle, Smooth; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins pp60(c-src); Quinones; Rabbits; Rifabutin; Signal Transduction; Sphingosine; src Homology Domains; Substrate Specificity; Wortmannin

1998
Gi-mediated activation of mitogen-activated protein kinase (MAPK) pathway by receptor mimetic basic secretagogues of connective tissue-type mast cells: bifurcation of arachidonic acid-induced release upstream of MAPK.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 289, Issue:3

    Topics: Androstadienes; Animals; Arachidonic Acids; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; Chromones; Connective Tissue Cells; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; GTP-Binding Protein alpha Subunits, Gi-Go; Histamine Release; In Vitro Techniques; Indole Alkaloids; Inositol Phosphates; Kinetics; Mast Cells; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morpholines; p-Methoxy-N-methylphenethylamine; Pertussis Toxin; Phosphotyrosine; Rats; Rats, Wistar; Signal Transduction; Tyrphostins; Vanadates; Virulence Factors, Bordetella; Wortmannin

1999
Phosphatidylinositol 3'-kinase-mediated calcium mobilization regulates chemotaxis in phosphatidic acid-stimulated human neutrophils.
    Biochimica et biophysica acta, 2000, Jan-03, Volume: 1483, Issue:1

    Topics: Calcium; Cells, Cultured; Chemotaxis; Chromones; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Enzyme Precursors; Humans; Intracellular Signaling Peptides and Proteins; Isoenzymes; Morpholines; Neutrophils; Phosphatidic Acids; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phospholipase C gamma; Phosphorylation; Protein-Tyrosine Kinases; src-Family Kinases; Syk Kinase; Type C Phospholipases

2000
Involvement of Ras and Ral in chemotactic migration of skeletal myoblasts.
    Molecular and cellular biology, 2000, Volume: 20, Issue:13

    Topics: Animals; Butadienes; Calcimycin; Calcium; Cell Line; Cell Movement; Chemotaxis; Chromones; Egtazic Acid; Enzyme Inhibitors; Extracellular Matrix Proteins; Genes, ras; Growth Substances; Insulin-Like Growth Factor I; Isopropyl Thiogalactoside; MAP Kinase Kinase Kinase 1; Mice; Morpholines; Muscle, Skeletal; Nitriles; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Serine-Threonine Kinases; ral GTP-Binding Proteins; ras Proteins; Signal Transduction

2000
Mechanisms of thrombin-induced MAPK activation associated with cell proliferation in human cultured tracheal smooth muscle cells.
    Cellular signalling, 2001, Volume: 13, Issue:4

    Topics: Androstadienes; Benzoquinones; Blotting, Western; Cell Division; Cells, Cultured; Chelating Agents; Chromones; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Estrenes; Flavonoids; Genistein; Humans; Indoles; Lactams, Macrocyclic; Maleimides; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morpholines; Muscle, Smooth; Pertussis Toxin; Phosphatidylinositol 3-Kinases; Phosphorylation; Plasmids; Protein Isoforms; Protein Kinase C; Proto-Oncogene Proteins c-raf; Pyrrolidinones; Quinones; ras Proteins; Rifabutin; Thrombin; Time Factors; Trachea; Transfection; Virulence Factors, Bordetella; Wortmannin

2001
Signal transduction pathways for activation of extracellular signal-regulated kinase by arachidonic acid in rat neutrophils.
    Journal of leukocyte biology, 2001, Volume: 69, Issue:4

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Androstadienes; Animals; Arachidonic Acid; Arachidonic Acids; Butadienes; Calcium; Carbazoles; Chelating Agents; Chromones; Cyclooxygenase Inhibitors; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Estrenes; Flavonoids; GTP-Binding Protein alpha Subunits, Gi-Go; Heterotrimeric GTP-Binding Proteins; Indoles; Lipoxygenase Inhibitors; Maleimides; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morpholines; Neutrophils; Nitriles; Pertussis Toxin; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Processing, Post-Translational; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Type C Phospholipases; Virulence Factors, Bordetella; Wortmannin

2001
Neuronal survival induced by neurotrophins requires calmodulin.
    The Journal of cell biology, 2001, Aug-06, Volume: 154, Issue:3

    Topics: Animals; Brain-Derived Neurotrophic Factor; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cell Membrane; Cell Survival; Chelating Agents; Chromones; Egtazic Acid; Enzyme Inhibitors; Green Fluorescent Proteins; Indicators and Reagents; Luminescent Proteins; Morpholines; Nerve Growth Factor; Neurons; PC12 Cells; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Recombinant Proteins; Signal Transduction; Sulfonamides

2001
Hydrogen peroxide activates endothelial nitric-oxide synthase through coordinated phosphorylation and dephosphorylation via a phosphoinositide 3-kinase-dependent signaling pathway.
    The Journal of biological chemistry, 2002, Feb-22, Volume: 277, Issue:8

    Topics: Animals; Aorta; Arginine; Calcium Signaling; Cells, Cultured; Chromones; Citrulline; Egtazic Acid; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Hydrogen Peroxide; Kinetics; Morpholines; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphoserine; Phosphothreonine; Quinazolines; Signal Transduction; Swine; Tyrphostins

2002
Signalling components underlying platelet aggregation to a Ca2+ ionophore and a phorbol ester.
    Platelets, 2001, Volume: 12, Issue:8

    Topics: Adenosine Diphosphate; Androstadienes; Calcimycin; Calcium Signaling; Chromones; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Activation; Humans; Indoles; Ionophores; Morpholines; Phosphatidylinositol 3-Kinases; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Serotonin; Signal Transduction; Tetradecanoylphorbol Acetate; Thromboxanes; Type C Phospholipases; Wortmannin

2001
Regulation of protein kinase C in Escherichia coli K1 invasion of human brain microvascular endothelial cells.
    The Journal of biological chemistry, 2002, Apr-05, Volume: 277, Issue:14

    Topics: Actins; Alanine; Binding Sites; Blotting, Western; Brain; Cells, Cultured; Chromones; Cytosol; Dose-Response Relationship, Drug; Egtazic Acid; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Escherichia coli; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Gene Expression Regulation; Genes, Dominant; Humans; Isoenzymes; Microcirculation; Microscopy, Fluorescence; Morpholines; Mutation; Phosphatidylinositol 3-Kinases; Phosphorylation; Precipitin Tests; Protein Binding; Protein Isoforms; Protein Kinase C; Protein Kinase C-alpha; Protein Transport; Protein-Tyrosine Kinases; Spectrophotometry; Time Factors; Transfection

2002
Immediate and delayed VEGF-mediated NO synthesis in endothelial cells: role of PI3K, PKC and PLC pathways.
    British journal of pharmacology, 2002, Volume: 137, Issue:7

    Topics: 1-Methyl-3-isobutylxanthine; Androstadienes; Animals; Calcimycin; Calcium; Cattle; Cells, Cultured; Chelating Agents; Chromones; Cyclic GMP; Diterpenes; Dose-Response Relationship, Drug; Egtazic Acid; Endothelial Growth Factors; Endothelium, Vascular; Enzyme Inhibitors; Ginkgolides; Indoles; Intercellular Signaling Peptides and Proteins; Ionophores; Lactones; Lymphokines; Maleimides; Morpholines; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroprusside; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase C; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Serine; Signal Transduction; Time Factors; Type C Phospholipases; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Wortmannin

2002
ERKs activation and calcium signaling are both required for VEGF induction by vanadium in mouse epidermal Cl41 cells.
    Molecular and cellular biochemistry, 2005, Volume: 279, Issue:1-2

    Topics: Animals; Calcium Signaling; Cell Line; Chelating Agents; Chromones; Egtazic Acid; Enzyme Inhibitors; Epidermis; Flavonoids; MAP Kinase Kinase Kinases; Mice; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Time Factors; Transfection; Vanadium; Vascular Endothelial Growth Factor A

2005
Essential role of PI-3K, ERKs and calcium signal pathways in nickel-induced VEGF expression.
    Molecular and cellular biochemistry, 2005, Volume: 279, Issue:1-2

    Topics: Animals; Calcium Signaling; Cell Line; Chelating Agents; Chromones; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Epidermis; Flavonoids; Mice; Mitogen-Activated Protein Kinases; Morpholines; Nickel; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Time Factors; Vascular Endothelial Growth Factor A

2005
Propionate induces pH(i) changes through calcium flux, ERK1/2, p38, and PKC in bovine neutrophils.
    Veterinary immunology and immunopathology, 2007, Feb-15, Volume: 115, Issue:3-4

    Topics: Animals; Butadienes; Calcium; Cattle; Chelating Agents; Chromones; Egtazic Acid; Extracellular Signal-Regulated MAP Kinases; Female; Hydrogen-Ion Concentration; Imidazoles; Indoles; Ionomycin; Maleimides; Morpholines; Neutrophils; Nitriles; p38 Mitogen-Activated Protein Kinases; Propionates; Protein Kinase C; Protein Kinase Inhibitors; Pyridines; Sodium-Hydrogen Exchangers; Spectrometry, Fluorescence

2007
Taurodeoxycholate modulates apical Cl-/OH- exchange activity in Caco2 cells.
    Digestive diseases and sciences, 2007, Volume: 52, Issue:5

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Alkaloids; Antiporters; Benzophenanthridines; Caco-2 Cells; Calcium; Chelating Agents; Chlorides; Chromones; Diarrhea; Dose-Response Relationship, Drug; Egtazic Acid; Glycochenodeoxycholic Acid; Humans; Hydrogen-Ion Concentration; Intestinal Mucosa; Morpholines; Organic Anion Transporters, Sodium-Dependent; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Protein Kinase C beta; Protein Kinase Inhibitors; Signal Transduction; Sodium; Symporters; Taurodeoxycholic Acid; Time Factors

2007
Distinct Ca2+ requirement for NO production between proteinase-activated receptor 1 and 4 (PAR1 and PAR4) in vascular endothelial cells.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 322, Issue:2

    Topics: Androstadienes; Animals; Calcium; Cattle; Cell Line; Cells, Cultured; Chromones; Dose-Response Relationship, Drug; Egtazic Acid; Endothelial Cells; Enzyme Inhibitors; GTP-Binding Protein alpha Subunits; Humans; Morpholines; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Oligopeptides; Peptides, Cyclic; Pertussis Toxin; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Receptor, PAR-1; Receptors, Thrombin; Swine; Wortmannin

2007
Estrogen and the Ca2+-mobilizing agonist ATP evoke acute NO synthesis via distinct pathways in an individual human vascular endothelium-derived cell.
    American journal of physiology. Cell physiology, 2008, Volume: 294, Issue:6

    Topics: Adenosine Triphosphate; Apamin; Calcium Signaling; Cell Line; Charybdotoxin; Chelating Agents; Chromones; Cytophotometry; Egtazic Acid; Endothelial Cells; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Flavonoids; Fulvestrant; Humans; Membrane Potentials; Mitogen-Activated Protein Kinases; Morpholines; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Patch-Clamp Techniques; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Potassium Channel Blockers; Potassium Channels, Calcium-Activated; Protein Kinase Inhibitors; Time Factors; Up-Regulation

2008
Obligatory role for phosphatidylinositol 4,5-bisphosphate in activation of native TRPC1 store-operated channels in vascular myocytes.
    The Journal of physiology, 2009, Feb-01, Volume: 587, Issue:3

    Topics: 1-Phosphatidylinositol 4-Kinase; Androstadienes; Animals; Antibodies, Phospho-Specific; Benzophenanthridines; Chelating Agents; Chromones; Egtazic Acid; Immunologic Factors; Immunoprecipitation; Indoles; Membrane Potentials; Morpholines; Myocytes, Smooth Muscle; Phosphatidylinositol 4,5-Diphosphate; Portal Vein; Protein Kinase C; Protein Kinase Inhibitors; Rabbits; TRPC Cation Channels; Wortmannin

2009
Modulation of ileal apical Na+-dependent bile acid transporter ASBT by protein kinase C.
    American journal of physiology. Gastrointestinal and liver physiology, 2009, Volume: 297, Issue:3

    Topics: Bile Acids and Salts; Caco-2 Cells; Calcium; Cell Membrane; Chelating Agents; Chromones; Egtazic Acid; Enzyme Activators; Humans; Ileum; Indoles; Intestinal Mucosa; Kinetics; Maleimides; Morpholines; Organic Anion Transporters, Sodium-Dependent; Peptides; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Symporters; Tetradecanoylphorbol Acetate; Transfection

2009
Gomisin A induces Ca2+-dependent activation of eNOS in human coronary artery endothelial cells.
    Journal of ethnopharmacology, 2009, Sep-07, Volume: 125, Issue:2

    Topics: Calcium; Cells, Cultured; Chelating Agents; Chromones; Coronary Vessels; Cyclooctanes; Dioxoles; Dose-Response Relationship, Drug; Egtazic Acid; Endothelial Cells; Enzyme Inhibitors; Fruit; Humans; Lignans; Morpholines; Nitric Oxide; Nitric Oxide Synthase Type III; Plant Extracts; Schisandra; Time Factors; Vasodilator Agents

2009
Combined effects of PI3K and SRC kinase inhibitors with imatinib on intracellular calcium levels, autophagy, and apoptosis in CML-PBL cells.
    Cell cycle (Georgetown, Tex.), 2013, Sep-01, Volume: 12, Issue:17

    Topics: Apoptosis; Autophagy; Benzamides; Calcium; Calcium Signaling; Cell Line, Tumor; Chromones; Drug Synergism; Egtazic Acid; Humans; Imatinib Mesylate; Inositol Phosphates; Intracellular Space; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Morpholines; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Piperazines; Protein Kinase Inhibitors; Pyrazoles; Pyrimidines; src-Family Kinases; Thapsigargin

2013
Carbon monoxide releasing molecule induces endothelial nitric oxide synthase activation through a calcium and phosphatidylinositol 3-kinase/Akt mechanism.
    Vascular pharmacology, 2016, Volume: 87

    Topics: Androstadienes; Animals; Calcium; Carbon Monoxide; Cattle; Chromones; Egtazic Acid; Endothelial Cells; Endothelium, Vascular; Morpholines; Nitric Oxide Synthase Type III; Organometallic Compounds; Phosphatidylinositol 3-Kinase; Phosphorylation; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Time Factors; Wortmannin

2016
ZnSO
    Toxicology in vitro : an international journal published in association with BIBRA, 2018, Volume: 48

    Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Chelating Agents; Child; Chromones; Dibutyl Phthalate; Egtazic Acid; Endoplasmic Reticulum Stress; Heat-Shock Proteins; Humans; Male; Morpholines; Phosphorylation; Plasticizers; Primary Cell Culture; Rats; Rats, Sprague-Dawley; Sertoli Cells; Vimentin; Zinc Sulfate

2018