efonidipine has been researched along with nisoldipine in 6 studies
| Studies (efonidipine) | Trials (efonidipine) | Recent Studies (post-2010) (efonidipine) | Studies (nisoldipine) | Trials (nisoldipine) | Recent Studies (post-2010) (nisoldipine) |
|---|---|---|---|---|---|
| 129 | 18 | 30 | 803 | 168 | 51 |
| Protein | Taxonomy | efonidipine (IC50) | nisoldipine (IC50) |
|---|---|---|---|
| Cytochrome P450 1A2 | Homo sapiens (human) | 1 | |
| Adenosine receptor A3 | Homo sapiens (human) | 7.12 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 7.12 | |
| Voltage-dependent L-type calcium channel subunit alpha-1C | Rattus norvegicus (Norway rat) | 0.003 | |
| Adenosine receptor A2a | Homo sapiens (human) | 4.058 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 7.12 | |
| Voltage-dependent L-type calcium channel subunit alpha-1C | Homo sapiens (human) | 0.003 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (66.67) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Horinouchi, M; Komada, F; Nishiguchi, K; Ohmoto, N; Ohnishi, N; Okumura, K; Sakaeda, T; Takara, K; Tanigawara, Y; Yokoyama, T | 1 |
| Higashino, R; Ito, S; Kurimoto, T; Matsuda, K; Takei, M; Tanaka, T | 1 |
| Fujikura, N; Masuda, Y; Shikada, K; Tanaka, S; Yokoyama, T | 2 |
| Fukuta, Y; Higashino, R; Inoue, N; Jin, H; Kurimoto, T; Sato, R; Tamaki, H | 1 |
| Hojo, M; Horiba, M; Kamiya, K; Kodama, I; Lee, JK; Miwa, K; Muto, T; Opthof, T; Ueda, N; Yasui, K | 1 |
6 other study(ies) available for efonidipine and nisoldipine
| Article | Year |
|---|---|
Effects of 12 Ca2+ antagonists on multidrug resistance, MDR1-mediated transport and MDR1 mRNA expression.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Calcium Channel Blockers; Cell Line; Digoxin; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Gene Expression; Humans; Nifedipine; Paclitaxel; RNA, Messenger; Swine; Tritium; Tumor Cells, Cultured; Verapamil; Vinblastine | 2002 |
[Effect of efonidipine hydrochloride (NZ-105) on modification of low density lipoprotein induced by rat cultured endothelial cells].
Topics: Animals; Arteriosclerosis; Calcium Channel Blockers; Cells, Cultured; Depression, Chemical; Dihydropyridines; Dose-Response Relationship, Drug; Endothelium; Lipoproteins, LDL; Male; Nisoldipine; Nitrophenols; Organophosphorus Compounds; Rats; Rats, Wistar | 1995 |
[Effect of efonidipine hydrochloride on myocardial oxygen balance in anesthetized dogs].
Topics: Anesthesia; Animals; Blood Pressure; Calcium Channel Blockers; Coronary Circulation; Dihydropyridines; Dogs; Female; Heart Rate; Male; Myocardium; Nifedipine; Nisoldipine; Nitrophenols; Organophosphorus Compounds; Oxygen Consumption; Thoracotomy | 1996 |
[Effect of efonidipine hydrochloride (NZ-105), a dihydropyridine derivative with calcium antagonistic action, on myocardial oxygen tension in anesthetized dogs].
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Coronary Circulation; Dihydropyridines; Dogs; Myocardium; Nifedipine; Nisoldipine; Nitrophenols; Organophosphorus Compounds; Oxygen Consumption; Partial Pressure | 1996 |
Inhibitory effects of efonidipine hydrochloride on contraction induced by several vasoconstrictors in porcine coronary artery: comparison with effects of nifedipine and nisoldipine.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Binding, Competitive; Calcium Channel Blockers; Coronary Vessels; Dihydropyridines; Endothelin-1; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Nisoldipine; Nitrophenols; Organophosphorus Compounds; Potassium; Prostaglandin Endoperoxides, Synthetic; Serotonin; Swine; Thromboxane A2; Vasoconstrictor Agents | 1997 |
T-type Ca2+ channel blockers prevent cardiac cell hypertrophy through an inhibition of calcineurin-NFAT3 activation as well as L-type Ca2+ channel blockers.
Topics: Active Transport, Cell Nucleus; Animals; Calcineurin; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Cattle; Cells, Cultured; Dihydropyridines; Hypertrophy; Mice; Myocardium; Myocytes, Cardiac; Natriuretic Peptide, Brain; Neurotoxins; NFATC Transcription Factors; Nisoldipine; Nitrophenols; Organophosphorus Compounds; Patch-Clamp Techniques; Scorpion Venoms | 2008 |