Page last updated: 2024-09-03

efonidipine and mepirodipine

efonidipine has been researched along with mepirodipine in 2 studies

Compound Research Comparison

Studies (efonidipine)	Trials (efonidipine)	Recent Studies (post-2010) (efonidipine)	Studies (mepirodipine)	Trials (mepirodipine)	Recent Studies (post-2010) (mepirodipine)
129	18	30	76	21	17

Protein Interaction Comparison

Protein	Taxonomy	mepirodipine (IC50)
Voltage-dependent L-type calcium channel subunit alpha-1C	Cavia porcellus (domestic guinea pig)	1.8333
ATP-dependent translocase ABCB1	Homo sapiens (human)	8.6
Voltage-dependent L-type calcium channel subunit alpha-1C	Homo sapiens (human)	2.15

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (100.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Katoh, M; Nakajima, M; Yamazaki, H; Yokoi, T	1
Horinouchi, M; Komada, F; Nishiguchi, K; Ohmoto, N; Ohnishi, N; Okumura, K; Sakaeda, T; Takara, K; Tanigawara, Y; Yokoyama, T	1

Other Studies

2 other study(ies) available for efonidipine and mepirodipine

Article	Year
Inhibitory potencies of 1,4-dihydropyridine calcium antagonists to P-glycoprotein-mediated transport: comparison with the effects on CYP3A4. Pharmaceutical research, 2000, Volume: 17, Issue:10 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Calcium Channel Blockers; Cell Line; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Daunorubicin; Digoxin; Dihydropyridines; Humans; Mixed Function Oxygenases; Substrate Specificity; Transfection; Tritium	2000
Effects of 12 Ca2+ antagonists on multidrug resistance, MDR1-mediated transport and MDR1 mRNA expression. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2002, Volume: 16, Issue:3 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Calcium Channel Blockers; Cell Line; Digoxin; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Gene Expression; Humans; Nifedipine; Paclitaxel; RNA, Messenger; Swine; Tritium; Tumor Cells, Cultured; Verapamil; Vinblastine	2002

Article

Year

Inhibitory potencies of 1,4-dihydropyridine calcium antagonists to P-glycoprotein-mediated transport: comparison with the effects on CYP3A4.

Pharmaceutical research, 2000, Volume: 17, Issue:10

Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Calcium Channel Blockers; Cell Line; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Daunorubicin; Digoxin; Dihydropyridines; Humans; Mixed Function Oxygenases; Substrate Specificity; Transfection; Tritium

2000

Effects of 12 Ca2+ antagonists on multidrug resistance, MDR1-mediated transport and MDR1 mRNA expression.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2002, Volume: 16, Issue:3

Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Calcium Channel Blockers; Cell Line; Digoxin; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Gene Expression; Humans; Nifedipine; Paclitaxel; RNA, Messenger; Swine; Tritium; Tumor Cells, Cultured; Verapamil; Vinblastine

2002