Compounds > efonidipine
Page last updated: 2024-09-03

efonidipine and flunarizine

efonidipine has been researched along with flunarizine in 2 studies

Compound Research Comparison

Studies
(efonidipine)		Trials
(efonidipine)		Recent Studies (post-2010)
(efonidipine)		Studies
(flunarizine)		Trials
(flunarizine)		Recent Studies (post-2010) (flunarizine)
12918301,269189153

Protein Interaction Comparison

ProteinTaxonomyefonidipine (IC50)flunarizine (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.669
Bile salt export pumpHomo sapiens (human)10
Sodium channel protein type 2 subunit alphaRattus norvegicus (Norway rat)0.49
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)1.339
Muscarinic acetylcholine receptor M4Homo sapiens (human)5.656
Muscarinic acetylcholine receptor M5Homo sapiens (human)1.107
Alpha-2A adrenergic receptorHomo sapiens (human)0.581
Adenosine receptor A3Homo sapiens (human)5.198
Muscarinic acetylcholine receptor M1Homo sapiens (human)2.936
Cytochrome P450 2C9 Homo sapiens (human)0.94
Angiotensin-converting enzymeOryctolagus cuniculus (rabbit)0.6058
D(2) dopamine receptorHomo sapiens (human)0.352
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)5.198
Alpha-2B adrenergic receptorHomo sapiens (human)1.893
Alpha-2C adrenergic receptorHomo sapiens (human)0.222
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)4.281
Muscarinic acetylcholine receptor M3Homo sapiens (human)1.479
Cannabinoid receptor 1Homo sapiens (human)3.028
D(1A) dopamine receptorHomo sapiens (human)3.874
Sodium-dependent noradrenaline transporter Homo sapiens (human)1.339
Alpha-1D adrenergic receptorHomo sapiens (human)1.085
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.407
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.669
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)4.281
Sodium-dependent serotonin transporterHomo sapiens (human)0.499
Delta-type opioid receptorMus musculus (house mouse)1.67
Histamine H1 receptorHomo sapiens (human)0.158
Mu-type opioid receptorHomo sapiens (human)5.236
D(3) dopamine receptorHomo sapiens (human)0.097
5-hydroxytryptamine receptor 2BHomo sapiens (human)1.088
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)5.198
Cytochrome P450 2J2Homo sapiens (human)0.8833
Voltage-dependent L-type calcium channel subunit beta-1Rattus norvegicus (Norway rat)0.08
Voltage-dependent calcium channel subunit alpha-2/delta-1Rattus norvegicus (Norway rat)0.08
D(2) dopamine receptorRattus norvegicus (Norway rat)0.228
Voltage-dependent N-type calcium channel subunit alpha-1BHomo sapiens (human)1.67
Sodium-dependent dopamine transporter Homo sapiens (human)0.584
Voltage-dependent N-type calcium channel subunit alpha-1BRattus norvegicus (Norway rat)0.08
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)0.6058
Nuclear receptor subfamily 3 group C member 3 Bos taurus (cattle)0.6058
Potassium channel subfamily K member 2 Bos taurus (cattle)2.5
Sigma non-opioid intracellular receptor 1Homo sapiens (human)0.025
Prostaglandin D2 receptor 2Homo sapiens (human)0.08

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Furuichi, H; Ito, S; Izumi, J; Kurimoto, T; Matsumura, T; Mori, T; Nishi, N; Suda, H; Takei, M; Tanaka, Y1
Akaike, N; Kim, CJ; Min, BI; Ogawa, S; Shin, MC; Tanaka, E1

Other Studies

2 other study(ies) available for efonidipine and flunarizine

ArticleYear
[Effect of efonidipine hydrochloride, a calcium channel blocker, on the experimental cerebral ischemia/anoxia].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1995, Volume: 105, Issue:6

    Topics: Animals; Brain Ischemia; Calcium Channel Blockers; Dihydropyridines; Flunarizine; Hypoxia; Male; Mice; Mice, Inbred ICR; Nicardipine; Nitrophenols; Organophosphorus Compounds; Rats; Rats, Wistar

1995
A selective T-type Ca2+ channel blocker R(-) efonidipine.
    Naunyn-Schmiedeberg's archives of pharmacology, 2008, Volume: 377, Issue:4-6

    Topics: Animals; Barium; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Channels, T-Type; Dihydropyridines; Dose-Response Relationship, Drug; Flunarizine; Mibefradil; Nitrophenols; Nystatin; Organophosphorus Compounds; Patch-Clamp Techniques; Potassium Channels, Calcium-Activated; Pyramidal Cells; Rats; Rats, Wistar; Sodium Channels

2008