Compounds > eflornithine

eflornithine and 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one

eflornithine has been researched along with 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's3 (75.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Caldarera, CM; Capanni, C; Flamigni, F; Guarnieri, C; Marmiroli, S; Stefanelli, C1
Guo, X; Liu, L; Rao, JN; Turner, DJ; Wang, JY; Zhang, HM; Zou, T1
Bhattacharya, S; Johnson, LR; Ray, RM1
Bachmann, AS; Borsics, T; Koomoa, DL; Wallick, CJ; Yco, LP1

Other Studies

4 other study(ies) available for eflornithine and 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one

ArticleYear
Phosphatidylinositol 3-kinase is required for the induction of ornithine decarboxylase in leukemia cells stimulated to growth.
    Biochemical and biophysical research communications, 1997, Oct-29, Volume: 239, Issue:3

    Topics: Androstadienes; Animals; Cell Division; Chromones; Eflornithine; Enzyme Induction; Leukemia L1210; Mice; Morpholines; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Phosphatidylinositol 3-Kinases; Polyenes; Sirolimus; Wortmannin

1997
Akt kinase activation blocks apoptosis in intestinal epithelial cells by inhibiting caspase-3 after polyamine depletion.
    The Journal of biological chemistry, 2004, May-21, Volume: 279, Issue:21

    Topics: Animals; Annexin A5; Apoptosis; Blotting, Western; Caspase 3; Caspase Inhibitors; Caspases; Cell Line; Cell Survival; Chromatography, High Pressure Liquid; Chromones; DNA, Complementary; Eflornithine; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Genes, Dominant; Glycogen Synthase Kinase 3; Intestines; Morpholines; Mutation; Open Reading Frames; Phosphorylation; Plasmids; Poly(ADP-ribose) Polymerases; Polyamines; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Signal Transduction; Time Factors; Transfection

2004
Decreased apoptosis in polyamine depleted IEC-6 cells depends on Akt-mediated NF-kappaB activation but not GSK3beta activity.
    Apoptosis : an international journal on programmed cell death, 2005, Volume: 10, Issue:4

    Topics: Androstadienes; Animals; Apoptosis; bcl-Associated Death Protein; Caspase 3; Caspase 9; Cell Line; Cell Nucleus; Chromones; Eflornithine; Enzyme Activation; Genes, Dominant; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; I-kappa B Proteins; Morpholines; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Phosphoserine; Polyamines; Protein Transport; Proto-Oncogene Proteins c-akt; Rats; Tumor Necrosis Factor-alpha; Wortmannin

2005
Ornithine decarboxylase inhibition by alpha-difluoromethylornithine activates opposing signaling pathways via phosphorylation of both Akt/protein kinase B and p27Kip1 in neuroblastoma.
    Cancer research, 2008, Dec-01, Volume: 68, Issue:23

    Topics: Biogenic Polyamines; Cell Line, Tumor; Chromones; Cyclin-Dependent Kinase Inhibitor p27; Eflornithine; Enzyme Activation; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Intracellular Signaling Peptides and Proteins; Morpholines; Neuroblastoma; Oncogene Protein v-akt; Ornithine Decarboxylase Inhibitors; Phosphorylation; Signal Transduction

2008