efegatran has been researched along with melagatran in 2 studies
| Studies (efegatran) | Trials (efegatran) | Recent Studies (post-2010) (efegatran) | Studies (melagatran) | Trials (melagatran) | Recent Studies (post-2010) (melagatran) |
|---|---|---|---|---|---|
| 43 | 3 | 0 | 185 | 32 | 19 |
| Protein | Taxonomy | efegatran (IC50) | melagatran (IC50) |
|---|---|---|---|
| Prothrombin | Homo sapiens (human) | 0.5239 | |
| Plasminogen | Homo sapiens (human) | 3.06 | |
| Cationic trypsin | Bos taurus (cattle) | 0.0112 | |
| Vitamin K-dependent protein C | Homo sapiens (human) | 1.3 | |
| Trypsin-1 | Homo sapiens (human) | 0.0119 | |
| Trypsin-2 | Homo sapiens (human) | 0.0119 | |
| Coagulation factor VII | Homo sapiens (human) | 3.3 | |
| Trypsin-3 | Homo sapiens (human) | 0.0119 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Deinum, J; Elg, M; Gustafsson, D | 1 |
| Adams, TE; Everse, SJ; Mann, KG | 1 |
2 other study(ies) available for efegatran and melagatran
| Article | Year |
|---|---|
The importance of enzyme inhibition kinetics for the effect of thrombin inhibitors in a rat model of arterial thrombosis.
Topics: Amino Acid Chloromethyl Ketones; Animals; Anticoagulants; Arginine; Azetidines; Benzylamines; Carotid Artery Thrombosis; Dose-Response Relationship, Drug; Fibrinolytic Agents; Glycine; Hemodynamics; Heparin; Hirudin Therapy; Hirudins; Kinetics; Male; Oligopeptides; Partial Thromboplastin Time; Peptide Fragments; Pipecolic Acids; Piperidines; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Sulfonamides; Thrombin; Thrombin Time | 1997 |
Predicting the pharmacology of thrombin inhibitors.
Topics: Anticoagulants; Arginine; Azetidines; Benzylamines; Blood Coagulation; Computer Simulation; Dose-Response Relationship, Drug; Glycine; Hirudins; Humans; Kinetics; Models, Cardiovascular; Oligopeptides; Peptide Fragments; Pipecolic Acids; Recombinant Proteins; Sulfonamides; Thrombin | 2003 |