Page last updated: 2024-08-25

efaroxan and moxonidine

efaroxan has been researched along with moxonidine in 48 studies

Research

Studies (48)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	14 (29.17)	18.2507
2000's	24 (50.00)	29.6817
2010's	10 (20.83)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Arrault, A; Guillaumet, G; Mérour, JY; Pfeiffer, B; Renard, P; Rettori, MC; Scalbert, E; Touzeau, F	1
Agbaba, D; Filipic, S; Nikolic, K	1
Agbaba, D; Azzali, E; Costantino, G; Glisic, S; Laurila, JM; Nikolic, K; Perovic, V; Pieroni, M; Radi, M; Scheinin, M; Srdic-Rajic, T; Tassini, S; Veljkovic, N; Vucicevic, J	1
Dreshaj, I; Ernsberger, P; Haxhiu, MA; Schäfer, SG	1
Carlisle, MA; Glavin, GB; Smyth, DD	1
Campbell, WR; Potter, DE	1
Chan, SL; Morgan, NG; Tsoli, E	1
Ernsberger, P; Kester, M; Separovic, D	1
Chan, CK; Head, GA	1
Chu, TC; Ogidigben, MJ; Potter, DE; Socci, RR	1
Dreshaj, IA; Ernsberger, P; Erokwu, BO; Haxhiu, MA; McFadden, CB	2
Ernsberger, P	1
Bock, C; Niederhoffer, N; Szabo, B	1
Fairbanks, CA; Wilcox, GL	1
Esteban, S; García-Sevilla, JA; Sastre-Coll, A	1
He, RR; Xu, YF	1
Lutz, EA; Shannon, HE	1
Dreshaj, IA; Ernsberger, P; Haxhiu, MA; Tolentino-Silva, FP; Waldbaum, S	1
Gutkowska, J; Mukaddam-Daher, S	1
Gandía, L; García, AG; Hernández-Guijo, JM; Jurkiewicz, A; Olivares, R; Ruiz-Nuño, A; Santos, WC	1
Khokhlova, ON; Medvedev, OS; Murashev, AN	1
Ogidigben, MJ; Potter, DE	2
Godwin, SJ; Head, GA; Parkin, ML	1
Dominiak, P; Häuser, W; Jungbluth, B; Raasch, W; Schäfer, U	2
Cao, C; Kang, CW; Kim, SH; Kim, SZ	1
Ernsberger, P; Koletsky, RJ; Velliquette, RA	1
Burgdorf, C; Engelhardt, A; Kurz, T; Raasch, W; Richardt, G; Schäfer, U	1
Korobov, NV; Kozaeva, LP; Medvedev, OS	1
El-Ayoubi, R; Gutkowska, J; Menaouar, A; Mukaddam-Daher, S	1
Hayashi, Y; Itoh, I; Iwasaki, M; Kagawa, K; Kamibayashi, T; Mashimo, T; Takada, K; Yamatodani, A	1
Gabilan, NH; Rodrigues, AL; Rosa, AO; Zeidan, MP; Zomkowski, AD	1
Gao, L; Wang, LG; Wang, W; Wang, WZ; Yuan, WJ	1
Guertin, PA; Lapointe, NP; Rouleau, P; Ung, RV	1
Hashimoto, M; Ono, H; Tanabe, M	1
Sun, N; Xiong, Q; Yang, J; Yang, R	1
Ni, X; Su, DF; Wang, JL; Wang, L; Wang, WZ; Wu, ZT; Yan, JJ; Yuan, WJ	1
Agbaba, D; Gemovic, B; Nikolic, K; Srdic-Rajic, T; Veljkovic, N	1
Aglawe, MM; Chopde, CT; Kotagale, NR; Taksande, BG; Tripathi, SJ; Umekar, MJ	1
Hayashi, K; Matsumura, Y; Ohkita, M; Sugiura, T; Takaoka, M; Tsutsui, H; Yukimura, T	1
García-Sevilla, JA; Keller, B	2
Hu, QK; Tan, X; Wang, WZ; Wang, YK; Wu, ZT; Yang, YH; Yu, Q; Yuan, WJ; Zhang, RW	1
Kuzmenko, NV; Pliss, MG; Tsyrlin, VA	1
Bernard, R; Bernstein, HG; Laube, G; Veh, RW; Weiss, T	1
Aglawe, MM; Chopde, CT; Gujar, S; Khade, SD; Kotagale, NR; Taksande, BG	1

Other Studies

48 other study(ies) available for efaroxan and moxonidine

Article	Year
Synthesis and biological evaluation of new 2-(4,5-dihydro-1H-imidazol-2-yl)-3,4-dihydro-2H-1,4-benzoxazine derivatives. Journal of medicinal chemistry, 2003, May-08, Volume: 46, Issue:10 Topics: Adrenal Medulla; Animals; Antihypertensive Agents; Binding Sites; Blood Pressure; Cattle; Frontal Lobe; Heart Rate; Imidazoles; Imidazoline Receptors; In Vitro Techniques; Kidney; Oxazines; Rabbits; Radioligand Assay; Rats; Rats, Inbred SHR; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Receptors, Drug; Stereoisomerism; Structure-Activity Relationship	2003
QSAR study of imidazoline antihypertensive drugs. Bioorganic & medicinal chemistry, 2008, Aug-01, Volume: 16, Issue:15 Topics: Antihypertensive Agents; Binding Sites; Imidazoline Receptors; Imidazolines; Ligands; Models, Molecular; Molecular Structure; Quantitative Structure-Activity Relationship	2008
A combined ligand- and structure-based approach for the identification of rilmenidine-derived compounds which synergize the antitumor effects of doxorubicin. Bioorganic & medicinal chemistry, 2016, 07-15, Volume: 24, Issue:14 Topics: Adrenergic alpha-Agonists; Antibiotics, Antineoplastic; Apoptosis; Doxorubicin; Drug Synergism; Humans; K562 Cells; Ligands; Molecular Structure; Oxazoles; Receptors, Adrenergic, alpha-2; Rilmenidine	2016
Selective antihypertensive action of moxonidine is mediated mainly by I1-imidazoline receptors in the rostral ventrolateral medulla. Journal of cardiovascular pharmacology, 1994, Volume: 24 Suppl 1 Topics: Adrenergic alpha-Antagonists; Affinity Labels; Animals; Antihypertensive Agents; Benzazepines; Benzofurans; Binding, Competitive; Blood Gas Analysis; Blood Pressure; Blood Pressure Determination; Cattle; Clonidine; Disease Models, Animal; Heart Rate; Hypertension; Imidazoles; Imidazoline Receptors; In Vitro Techniques; Medulla Oblongata; Microinjections; Radioligand Assay; Rats; Rats, Inbred SHR; Receptors, Drug	1994
Efaroxan acts peripherally to block the antisecretory and gastroprotective effects of moxonidine in rats. The Journal of pharmacology and experimental therapeutics, 1995, Volume: 274, Issue:2 Topics: Animals; Benzofurans; Dose-Response Relationship, Drug; Gastric Acid; Gastric Mucosa; Imidazoles; Imidazoline Receptors; Male; Rats; Rats, Sprague-Dawley; Receptors, Drug	1995
Potential role of imidazoline (I1) receptors in modulating aqueous humor dynamics. Journal of ocular pharmacology, 1994,Spring, Volume: 10, Issue:1 Topics: Administration, Topical; Animals; Aqueous Humor; Benzofurans; Brain; Catheters, Indwelling; Imidazoles; Imidazoline Receptors; Injections, Intraventricular; Intraocular Pressure; Male; Ocular Hypotension; Oxymetazoline; Pupil; Rabbits; Receptors, Drug	1994
The imidazoline I1 receptor agonist, moxonidine, inhibits insulin secretion from isolated rat islets of Langerhans. European journal of pharmacology, 1995, Sep-15, Volume: 284, Issue:1-2 Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Benzofurans; Cimetidine; Depression, Chemical; Female; Glucose; Histamine H2 Antagonists; Imidazoles; Imidazoline Receptors; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Rats; Rats, Wistar; Receptors, Drug	1995
Coupling of I1-imidazoline receptors to diacylglyceride accumulation in PC12 rat pheochromocytoma cells. Molecular pharmacology, 1996, Volume: 49, Issue:4 Topics: Animals; Benzofurans; Diglycerides; Dose-Response Relationship, Drug; Imidazoles; Imidazoline Receptors; Nerve Growth Factors; PC12 Cells; Phospholipase D; Rats; Receptors, Drug; Type C Phospholipases	1996
Relative importance of central imidazoline receptors for the antihypertensive effects of moxonidine and rilmenidine. Journal of hypertension, 1996, Volume: 14, Issue:7 Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Antihypertensive Agents; Benzofurans; Blood Pressure; Cardiac Catheterization; Clonidine; Dose-Response Relationship, Drug; Female; Heart Rate; Idazoxan; Imidazoles; Imidazoline Receptors; Injections, Intravenous; Male; Oxazoles; Rabbits; Receptors, Drug; Rilmenidine; Time Factors	1996
Potential mechanisms of moxonidine-induced ocular hypotension: role of norepinephrine. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 1997, Volume: 13, Issue:6 Topics: Administration, Topical; Animals; Antihypertensive Agents; Aqueous Humor; Benzofurans; Dopamine; Female; Imidazoles; Intraocular Pressure; Male; Norepinephrine; Ocular Hypotension; Rabbits; Superior Cervical Ganglion	1997
I1-imidazoline receptors and cholinergic outflow to the airways. Journal of the autonomic nervous system, 1998, Jul-15, Volume: 71, Issue:2-3 Topics: Acetylcholine; Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Benzofurans; Blood Pressure; Cholinergic Fibers; Dogs; Electric Stimulation; Heart Rate; Imidazoles; Imidazoline Receptors; Mechanoreceptors; Muscle Contraction; Muscle, Smooth; Nerve Endings; Neurons, Afferent; Receptors, Drug; Trachea; Vagus Nerve; Vasodilator Agents	1998
Arachidonic acid release from PC12 pheochromocytoma cells is regulated by I1-imidazoline receptors. Journal of the autonomic nervous system, 1998, Oct-15, Volume: 72, Issue:2-3 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Arachidonic Acid; Aristolochic Acids; Benzofurans; Enzyme Inhibitors; Guanabenz; Imidazoles; Imidazoline Receptors; PC12 Cells; Phenanthrenes; Phospholipases A; Phospholipases A2; Rats; Receptors, Drug	1998
Analysis of the receptor involved in the central hypotensive effect of rilmenidine and moxonidine. Naunyn-Schmiedeberg's archives of pharmacology, 1999, Volume: 359, Issue:4 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Benzazepines; Benzofurans; Blood Pressure; Dose-Response Relationship, Drug; Drug Interactions; Female; Heart Rate; Imidazoles; Imidazoline Receptors; Male; Methyldopa; Norepinephrine; Oxazoles; Rabbits; Receptors, Adrenergic, alpha-2; Receptors, Drug; Rilmenidine; Sympathetic Nervous System; Yohimbine	1999
Moxonidine, a selective alpha2-adrenergic and imidazoline receptor agonist, produces spinal antinociception in mice. The Journal of pharmacology and experimental therapeutics, 1999, Volume: 290, Issue:1 Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics, Non-Narcotic; Animals; Autoreceptors; Benzazepines; Benzofurans; Dose-Response Relationship, Drug; Female; Imidazoles; Imidazoline Receptors; Injections, Spinal; Male; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Nerve Endings; Norepinephrine; Pain Measurement; Receptors, Adrenergic, alpha-2; Receptors, Drug; Spinal Cord	1999
Effects of imidazoline drugs on tyrosine and tryptophan hydroxylase activity in rat brain in vivo. Annals of the New York Academy of Sciences, 1999, Jun-21, Volume: 881 Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Benzofurans; Brain; Clonidine; Dihydroxyphenylalanine; Imidazoles; Male; Quinolines; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Antagonists; Tryptophan Hydroxylase; Tyrosine 3-Monooxygenase	1999
Moxonidine acting centrally inhibits airway reflex responses. Annals of the New York Academy of Sciences, 1999, Jun-21, Volume: 881 Topics: Acetylcholine; Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Benzofurans; Blood Pressure; Decerebrate State; Dogs; Efferent Pathways; Electric Stimulation; Heart Rate; Imidazoles; Imidazoline Receptors; In Vitro Techniques; Lung; Muscle, Smooth; Nerve Fibers; Neurons, Afferent; Receptors, Drug; Reflex; Trachea; Vagus Nerve	1999
Effect of moxonidine on carotid sinus baroreflex in anesthetized rats. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1999, Volume: 20, Issue:7 Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Baroreflex; Benzofurans; Blood Pressure; Carotid Sinus; Imidazoles; Male; Rats; Vascular Resistance	1999
Effects of the I(1) imidazoline/alpha(2)-adrenergic receptor agonist moxonidine in comparison with clonidine in the formalin test in rats. Pain, 2000, Volume: 85, Issue:1-2 Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics, Non-Narcotic; Animals; Benzofurans; Clonidine; Dose-Response Relationship, Drug; Formaldehyde; Imidazoles; Imidazoline Receptors; Injections, Subcutaneous; Male; Pain; Pain Measurement; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Drug; Time Factors; Yohimbine	2000
alpha(2)-adrenergic receptors are not required for central anti-hypertensive action of moxonidine in mice. Brain research, 2000, Apr-17, Volume: 862, Issue:1-2 Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Amygdala; Animals; Antihypertensive Agents; Benzofurans; Binding, Competitive; Blood Pressure; Brain Chemistry; Glutamic Acid; Heart Rate; Hypertension; Imidazoles; Imidazoline Receptors; Injections, Intravenous; Medulla Oblongata; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Microinjections; Pons; Receptors, Adrenergic, alpha-2; Receptors, Drug	2000
Atrial natriuretic peptide is involved in renal actions of moxonidine. Hypertension (Dallas, Tex. : 1979), 2000, Volume: 35, Issue:6 Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Atrial Natriuretic Factor; Benzofurans; Cyclic GMP; Diuresis; Dose-Response Relationship, Drug; Female; Imidazoles; Imidazoline Receptors; Injections, Intravenous; Kidney; Natriuresis; Potassium; Rats; Rats, Sprague-Dawley; Receptors, Drug; Yohimbine	2000
Blockade by agmatine of catecholamine release from chromaffin cells is unrelated to imidazoline receptors. European journal of pharmacology, 2001, Apr-06, Volume: 417, Issue:1-2 Topics: Acetylcholine; Agmatine; Animals; Benzofurans; Binding Sites; Binding, Competitive; Calcium Channels; Catecholamines; Cattle; Cells, Cultured; Chromaffin Cells; Clonidine; Dose-Response Relationship, Drug; Electric Stimulation; Imidazoles; Imidazoline Receptors; Membrane Potentials; Potassium; Potassium Channels; Receptors, Drug; Receptors, Nicotinic; Sodium Channels	2001
Role of I(1)-imidazoline receptors and alpha2-adrenoceptors in hemodynamic effects of moxonidine administration into the rostroventrolateral medulla. Bulletin of experimental biology and medicine, 2001, Volume: 131, Issue:4 Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Benzofurans; Blood Pressure; Heart Rate; Hemodynamics; Imidazoles; Imidazoline Receptors; Male; Medulla Oblongata; Rats; Rats, Inbred SHR; Receptors, Adrenergic, alpha-2; Receptors, Drug; Yohimbine	2001
Central imidazoline (I(1)) receptors modulate aqueous hydrodynamics. Current eye research, 2001, Volume: 22, Issue:5 Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Aqueous Humor; Benzofurans; Brain; Dose-Response Relationship, Drug; Female; Imidazoles; Imidazoline Receptors; Injections, Intraventricular; Intraocular Pressure; Male; Rabbits; Receptors, Drug; Sympathectomy; Sympathetic Nervous System	2001
Importance of imidazoline-preferring receptors in the cardiovascular actions of chronically administered moxonidine, rilmenidine and clonidine in conscious rabbits. Journal of hypertension, 2003, Volume: 21, Issue:1 Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Antihypertensive Agents; Benzofurans; Blood Pressure; Cardiovascular System; Clonidine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fourth Ventricle; Heart Rate; Idazoxan; Imidazoles; Imidazoline Receptors; Injections, Intraventricular; Male; Oxazoles; Rabbits; Receptors, Drug; Rilmenidine	2003
Modification of noradrenaline release in pithed spontaneously hypertensive rats by I1-binding sites in addition to alpha2-adrenoceptors. The Journal of pharmacology and experimental therapeutics, 2003, Volume: 304, Issue:3 Topics: Adrenergic alpha-Antagonists; Agmatine; Animals; Antihypertensive Agents; Benzofurans; Binding Sites; Blood Pressure; Disease Models, Animal; Heart Rate; Idazoxan; Imidazoles; Male; Norepinephrine; Phenoxybenzamine; Rats; Rats, Inbred SHR; Receptors, Adrenergic, alpha-2	2003
Pharmacological evidence of a role for prejunctional imidazoline (I(1)) receptors in ocular function. Current eye research, 2002, Volume: 25, Issue:5 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Benzofurans; Brimonidine Tartrate; Cats; Dose-Response Relationship, Drug; Electric Stimulation; Imidazoles; Imidazoline Receptors; Nictitating Membrane; Ocular Physiological Phenomena; Platelet Aggregation Inhibitors; Quinoxalines; Receptors, Adrenergic, alpha-2; Receptors, Drug; Yohimbine	2002
Augmentation of moxonidine-induced increase in ANP release by atrial hypertrophy. American journal of physiology. Heart and circulatory physiology, 2004, Volume: 287, Issue:1 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Atrial Function; Atrial Natriuretic Factor; Benzofurans; Blood Pressure; Cardiomegaly; Clonidine; Heart Atria; Hemodynamics; Imidazoles; Imidazoline Receptors; Male; Rats; Rats, Sprague-Dawley; Receptors, Drug; Yohimbine	2004
The role of I(1)-imidazoline receptors and alpha(2)-adrenergic receptors in the modulation of glucose and lipid metabolism in the SHROB model of metabolic syndrome X. Annals of the New York Academy of Sciences, 2003, Volume: 1009 Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Benzofurans; Blood Pressure; Disease Models, Animal; Female; Glucagon; Glucose; Glucose Tolerance Test; Humans; Imidazoles; Imidazoline Receptors; Lipid Metabolism; Male; Metabolic Syndrome; Obesity; Oxazoles; Rats; Rats, Inbred SHR; Receptors, Adrenergic, alpha-2; Receptors, Drug; Rilmenidine; Yohimbine	2003
Moxonidine displays a presynaptic alpha-2-adrenoceptor-dependent synergistic sympathoinhibitory action at imidazoline-1 receptors. Annals of the New York Academy of Sciences, 2003, Volume: 1009 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Agmatine; Animals; Benzofurans; Bridged Bicyclo Compounds; Brimonidine Tartrate; Drug Synergism; Heart; Heptanes; Imidazoles; Imidazoline Receptors; Norepinephrine; Oxazoles; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Receptors, Drug; Rilmenidine; Sympathetic Nervous System; Sympatholytics; Yohimbine	2003
Norepinephrine release is reduced by I(1)-receptors in addition to alpha(2)-adrenoceptors. Annals of the New York Academy of Sciences, 2003, Volume: 1009 Topics: Adrenergic alpha-Antagonists; Agmatine; Animals; Benzofurans; Blood Pressure; Bridged Bicyclo Compounds; Electric Stimulation; Heptanes; Hypertension; Idazoxan; Imidazoles; Imidazoline Receptors; Male; Norepinephrine; Phenoxybenzamine; Rats; Rats, Inbred SHR; Receptors, Adrenergic, alpha-2; Receptors, Drug; Spinal Cord	2003
Effect of moxonidine on contractile activity of isolated large intestine in mice: role of alpha2-adrenoceptors and Ii-imidazoline receptors. Bulletin of experimental biology and medicine, 2004, Volume: 137, Issue:3 Topics: Animals; Benzofurans; Imidazoles; Imidazoline Receptors; In Vitro Techniques; Intestine, Large; Mice; Muscle Contraction; Receptors, Adrenergic, alpha-2; Receptors, Drug; Yohimbine	2004
Urinary responses to acute moxonidine are inhibited by natriuretic peptide receptor antagonist. British journal of pharmacology, 2005, Volume: 145, Issue:1 Topics: Animals; Antihypertensive Agents; Benzofurans; Clonidine; Cyclic GMP; Diuresis; Dose-Response Relationship, Drug; Female; Imidazoles; Imidazoline Receptors; Natriuresis; Natriuretic Peptides; Peptides, Cyclic; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Drug; Yohimbine	2005
Identification of the central imidazoline receptor subtype involved in modulation of halothane-epinephrine arrhythmias in rats. Anesthesia and analgesia, 2005, Volume: 101, Issue:6 Topics: Animals; Arrhythmias, Cardiac; Benzofurans; Blood Pressure; Dose-Response Relationship, Drug; Epinephrine; Halothane; Heart Rate; Imidazoles; Imidazoline Receptors; Male; Rats; Rats, Sprague-Dawley; Receptors, Drug	2005
Evidence for imidazoline receptors involvement in the agmatine antidepressant-like effect in the forced swimming test. European journal of pharmacology, 2007, Jun-22, Volume: 565, Issue:1-3 Topics: Agmatine; Animals; Antazoline; Antidepressive Agents; Benzofurans; Clonidine; Female; Imidazoles; Imidazoline Receptors; Male; Mice; Receptors, Adrenergic, alpha-2; Receptors, Drug; Receptors, N-Methyl-D-Aspartate; Swimming	2007
Sympathoexcitation of moxonidine in the caudal ventrolateral medulla is dependent on I1-imidazoline receptors in anesthetized rats. Neuroscience letters, 2007, Oct-16, Volume: 426, Issue:2 Topics: Adrenergic alpha-Antagonists; Anesthesia; Animals; Benzofurans; Blood Pressure; Dose-Response Relationship, Drug; Drug Interactions; Heart Rate; Imidazoles; Imidazoline Receptors; Male; Medulla Oblongata; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Sympatholytics; Yohimbine	2007
Effects of spinal alpha(2)-adrenoceptor and I(1)-imidazoline receptor activation on hindlimb movement induction in spinal cord-injured mice. The Journal of pharmacology and experimental therapeutics, 2008, Volume: 325, Issue:3 Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Benzofurans; Clonidine; Hindlimb; Imidazoles; Imidazoline Receptors; Male; Mice; Mice, Inbred Strains; Movement; Receptors, Adrenergic, alpha-2; Spinal Cord; Spinal Cord Injuries; Yohimbine	2008
Imidazoline I(1) receptor-mediated reduction of muscle rigidity in the reserpine-treated murine model of Parkinson's disease. European journal of pharmacology, 2008, Jul-28, Volume: 589, Issue:1-3 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antiparkinson Agents; Benzazepines; Benzofurans; Clonidine; Disease Models, Animal; Dose-Response Relationship, Drug; Electromyography; Idazoxan; Imidazoles; Imidazoline Receptors; Injections, Intraperitoneal; Ligands; Male; Mice; Muscle Rigidity; Muscle, Skeletal; Parkinsonian Disorders; Reserpine; Time Factors; Yohimbine	2008
Effect of moxonidine on the uveoscleral outflow: role of alpha2-adrenoceptors or i1 imidazoline receptors. Current eye research, 2009, Volume: 34, Issue:4 Topics: Administration, Topical; Adrenergic alpha-Antagonists; Animals; Aqueous Humor; Benzofurans; Bridged Bicyclo Compounds; Drug Synergism; Fluorescein-5-isothiocyanate; Heptanes; Imidazoles; Imidazoline Receptors; Prazosin; Rabbits; Receptors, Adrenergic, alpha-2; Sclera; Serum Albumin, Bovine; Uvea; Yohimbine	2009
Low dose of moxonidine within the rostral ventrolateral medulla improves the baroreflex sensitivity control of sympathetic activity in hypertensive rat. Acta pharmacologica Sinica, 2009, Volume: 30, Issue:12 Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Baroreflex; Benzofurans; Blood Pressure; Dose-Response Relationship, Drug; Imidazoles; Imidazoline Receptors; Iontophoresis; Kidney; Medulla Oblongata; Microinjections; Neurons; Rats; Rats, Inbred SHR; Sympathetic Nervous System; Synaptic Potentials; Yohimbine	2009
Imidazoline-1 receptor ligands as apoptotic agents: pharmacophore modeling and virtual docking study. Combinatorial chemistry & high throughput screening, 2013, Volume: 16, Issue:4 Topics: Antineoplastic Agents; Apoptosis; Benzofurans; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Imidazoles; Imidazoline Receptors; K562 Cells; Ligands; Models, Molecular; Molecular Docking Simulation; Oxazoles; Quantitative Structure-Activity Relationship; Rilmenidine; Tumor Cells, Cultured	2013
Evidences for the agmatine involvement in antidepressant like effect of bupropion in mouse forced swim test. Pharmacology, biochemistry, and behavior, 2013, Volume: 107 Topics: Agmatine; Animals; Antidepressive Agents; Arginine; Benzofurans; Biguanides; Bupropion; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Eflornithine; Guanidines; Idazoxan; Imidazoles; Immobility Response, Tonic; Injections, Intraventricular; Male; Mice; Motor Activity	2013
Protective effect of moxonidine on ischemia/reperfusion-induced acute kidney injury through α2/imidazoline I1 receptor. European journal of pharmacology, 2013, Oct-15, Volume: 718, Issue:1-3 Topics: Acute Kidney Injury; Animals; Benzofurans; Cytoprotection; Imidazoles; Imidazoline Receptors; Kidney; Male; Norepinephrine; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Sympathetic Nervous System; Veins	2013
Immunodetection and subcellular distribution of imidazoline receptor proteins with three antibodies in mouse and human brains: Effects of treatments with I1- and I2-imidazoline drugs. Journal of psychopharmacology (Oxford, England), 2015, Volume: 29, Issue:9 Topics: Adult; Animals; Antibodies; Benzofurans; Binding Sites; Brain; Cell Membrane; Cytosol; Female; Humans; Idazoxan; Imidazoles; Imidazoline Receptors; Imidazolines; Male; Mice; Styrenes; Up-Regulation	2015
Centrally acting drug moxonidine decreases reactive oxygen species via inactivation of the phosphoinositide-3 kinase signaling in the rostral ventrolateral medulla in hypertensive rats. Journal of hypertension, 2016, Volume: 34, Issue:5 Topics: Animals; Antihypertensive Agents; Benzofurans; Disease Models, Animal; Hypertension; Imidazoles; Male; Medulla Oblongata; Phosphatidylinositol 3-Kinases; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reactive Oxygen Species; Signal Transduction	2016
Inhibitory effects of imidazoline receptor ligands on basal and kainic acid-induced neurotoxic signalling in mice. Journal of psychopharmacology (Oxford, England), 2016, Volume: 30, Issue:9 Topics: Animals; Benzofurans; Cerebral Cortex; Cyclin-Dependent Kinase 5; Glutamic Acid; Hippocampus; Idazoxan; Imidazoles; Imidazoline Receptors; Kainic Acid; Ligands; Male; Mice; Neurodegenerative Diseases; Neuroprotective Agents; Styrenes; Time Factors	2016
[ADRENERGIC AND IMIDAZOLINE MECHANISMS OF CIRCULATION CENTRAL REGULATION IN RATS OF DIFFERENT LINES]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2016, Volume: 102, Issue:4 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Baroreflex; Benzofurans; Blood Pressure; Brain; Clonidine; Heart Rate; Imidazoles; Imidazoline Receptors; Male; Rats; Rats, Inbred SHR; Rats, Wistar; Sympathetic Nervous System; Yohimbine	2016
Agmatine modulates spontaneous activity in neurons of the rat medial habenular complex-a relevant mechanism in the pathophysiology and treatment of depression? Translational psychiatry, 2018, 09-24, Volume: 8, Issue:1 Topics: Action Potentials; Agmatine; Animals; Benzofurans; Depression; Female; Habenula; Humans; Idazoxan; Imidazoles; Imidazoline Receptors; Male; Middle Aged; Neurons; Rats, Wistar; Ureohydrolases	2018
Agmatine Inhibits Behavioral Sensitization to Ethanol Through Imidazoline Receptors. Alcoholism, clinical and experimental research, 2019, Volume: 43, Issue:4 Topics: Agmatine; Animals; Arginine; Benzofurans; Biguanides; Central Nervous System Sensitization; Dose-Response Relationship, Drug; Drug Interactions; Ethanol; Guanidines; Idazoxan; Imidazoles; Imidazoline Receptors; Infusions, Intraventricular; Male; Mice; Microinjections; Motor Activity	2019