Page last updated: 2024-08-25

efaroxan and diazoxide

efaroxan has been researched along with diazoxide in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (63.64)18.2507
2000's2 (18.18)29.6817
2010's2 (18.18)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chan, SL; Morgan, NG; Stillings, MR1
Chan, SL; Dunne, MJ; Morgan, NG; Stillings, MR1
Chan, SL; Morgan, NG1
Haque, M; Kulkarni, RN; MacDermot, J; Olmos, G1
Brown, CA; Morgan, NG1
Martín-Ruiz, R; Pineda, J; Ruiz-Ortega, JA; Ugedo, L1
Ammälä, C; Chapman, JC; Cosgrove, KE; Dunne, MJ; Flatt, PR; Giesberts, AN; Hashmi, MN; McClenaghan, NH; Shepherd, RM; White, SJ1
Chan, SL; Morgan, NG; Mourtada, M1
Cooper, EJ; Hills, CE; Hudson, AL; Morgan, NG; Parker, CA; Squires, PE1
Henquin, JC; Nenquin, M; Szollosi, A1
Adorjan, I; Bauer, L; Belz, M; Brunmair, B; de Cillia, VA; Fenzl, A; Frobel, K; Fürnsinn, C; Gruber, D; Lehner, Z; Luger, A; Rustenbeck, I; Stadlbauer, K1

Other Studies

11 other study(ies) available for efaroxan and diazoxide

ArticleYear
Mechanisms involved in stimulation of insulin secretion by the hypoglycaemic alpha-adrenergic antagonist, DG-5128.
    Biochemical and biophysical research communications, 1991, May-15, Volume: 176, Issue:3

    Topics: Adrenergic alpha-Antagonists; Animals; Benzofurans; Diazoxide; Dioxanes; Dose-Response Relationship, Drug; Hypoglycemic Agents; Idazoxan; Imidazoles; In Vitro Techniques; Islets of Langerhans; Kinetics; Male; Phentolamine; Rats; Rats, Inbred Strains

1991
The alpha 2-adrenoceptor antagonist efaroxan modulates K+ATP channels in insulin-secreting cells.
    European journal of pharmacology, 1991, Oct-29, Volume: 204, Issue:1

    Topics: Adenosine Triphosphate; Adrenergic alpha-Antagonists; Animals; Benzofurans; Diazoxide; Drug Interactions; Imidazoles; Insulin; Insulin Secretion; Islets of Langerhans; Male; Potassium Channels; Rats; Rats, Inbred Strains

1991
Stimulation of insulin secretion by efaroxan may involve interaction with potassium channels.
    European journal of pharmacology, 1990, Jan-25, Volume: 176, Issue:1

    Topics: Animals; Benzofurans; Diazoxide; Glucose; Hypoglycemic Agents; Imidazoles; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Potassium Channels; Rats; Rats, Inbred Strains

1990
Imidazolines stimulate release of insulin from RIN-5AH cells independently from imidazoline I1 and I2 receptors.
    European journal of pharmacology, 1994, Sep-01, Volume: 262, Issue:1-2

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Affinity Labels; Animals; Benzofurans; Binding, Competitive; Clonidine; Clorgyline; Diazoxide; Dioxanes; Guanidines; Idazoxan; Imidazoles; Imidazoline Receptors; Insulin; Insulinoma; Ligands; Pancreatic Neoplasms; Potassium Channels; Rats; Receptors, Drug; Regression Analysis; Software; Tumor Cells, Cultured

1994
Control of insulin secretion by imidazolines in rat pancreatic islets.
    Biochemical Society transactions, 1993, Volume: 21, Issue:2

    Topics: Animals; Benzofurans; Diazoxide; Dioxanes; Idazoxan; Imidazoles; Insulin; Insulin Secretion; Islets of Langerhans; Rats

1993
Stimulation of locus coeruleus neurons by non-I1/I2-type imidazoline receptors: an in vivo and in vitro electrophysiological study.
    British journal of pharmacology, 1998, Volume: 125, Issue:8

    Topics: Adenosine Triphosphate; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Benzofurans; Diazoxide; Electrophysiology; Idazoxan; Imidazoles; Imidazoline Receptors; In Vitro Techniques; Ligands; Locus Coeruleus; Male; Neurons; Potassium Channels; Rats; Receptors, Adrenergic, alpha-2; Receptors, Drug; Vasodilator Agents

1998
ATP-sensitive potassium channels and efaroxan-induced insulin release in the electrofusion-derived BRIN-BD11 beta-cell line.
    Diabetes, 1999, Volume: 48, Issue:12

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adrenergic alpha-Antagonists; Animals; Benzofurans; Cell Fusion; Cell Line; Diazoxide; Glucose; Imidazoles; Insulin; Insulin Secretion; Insulinoma; Islets of Langerhans; Membrane Potentials; Pancreatic Neoplasms; Phentolamine; Pinacidil; Potassium Channels; Tolbutamide; Tumor Cells, Cultured

1999
Characterization of a KATP channel-independent pathway involved in potentiation of insulin secretion by efaroxan.
    Diabetes, 2001, Volume: 50, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine Triphosphate; Animals; Benzofurans; Bucladesine; Cyclic AMP; Diazoxide; Glucose; Imidazoles; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Permeability; Phosphodiesterase Inhibitors; Potassium Channels; Rats; Rats, Wistar

2001
Comparative effects of efaroxan and beta-carbolines on the secretory activity of rodent and human beta cells.
    Annals of the New York Academy of Sciences, 2003, Volume: 1009

    Topics: Adrenergic alpha-Antagonists; Animals; Benzofurans; Binding Sites; Calcium; Carbolines; Cells, Cultured; Diazoxide; Glucose; Humans; Imidazoles; Insulin; Insulin Secretion; Islets of Langerhans; Ligands; Male; Rats; Rats, Wistar

2003
Pharmacological stimulation and inhibition of insulin secretion in mouse islets lacking ATP-sensitive K+ channels.
    British journal of pharmacology, 2010, Feb-01, Volume: 159, Issue:3

    Topics: Animals; Benzofurans; Calcium; Cytosol; Diazoxide; Female; Imidazoles; Imidazolines; Insulin; Insulin Secretion; Insulin-Secreting Cells; KATP Channels; Mice; Mice, Knockout; Phentolamine; Pinacidil; Potassium Channels; Tolbutamide

2010
Mechanisms of antihyperglycaemic action of efaroxan in mice: time for reappraisal of α2A-adrenergic antagonism in the treatment of type 2 diabetes?
    Diabetologia, 2012, Volume: 55, Issue:11

    Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Benzofurans; Brimonidine Tartrate; Calcium; Cells, Cultured; Diabetes Mellitus, Type 2; Diazoxide; Female; Hyperglycemia; Imidazoles; Insulin; Insulin-Secreting Cells; KATP Channels; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Patch-Clamp Techniques; Quinoxalines; Yohimbine

2012