efaroxan has been researched along with agmatine in 18 studies
*Agmatine: Decarboxylated arginine, isolated from several plant and animal sources, e.g., pollen, ergot, herring sperm, octopus muscle. [MeSH]
*Agmatine: Decarboxylated arginine, isolated from several plant and animal sources, e.g., pollen, ergot, herring sperm, octopus muscle. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (16.67) | 18.2507 |
| 2000's | 7 (38.89) | 29.6817 |
| 2010's | 7 (38.89) | 24.3611 |
| 2020's | 1 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Arrault, A; Guillaumet, G; Mérour, JY; Pfeiffer, B; Renard, P; Rettori, MC; Scalbert, E; Touzeau, F | 1 |
| Brown, CA; Chan, SL; Morgan, NG; Tsoli, E | 1 |
| Berdeu, D; Bertrand, G; Loubatières-Mariani, MM; Puech, R | 1 |
| Dunne, MJ; Hashmi, MN; Kane, C; Shepherd, RM; Squires, PE | 1 |
| Gandía, L; García, AG; Hernández-Guijo, JM; Jurkiewicz, A; Olivares, R; Ruiz-Nuño, A; Santos, WC | 1 |
| Dominiak, P; Häuser, W; Jungbluth, B; Raasch, W; Schäfer, U | 2 |
| Burgdorf, C; Engelhardt, A; Kurz, T; Raasch, W; Richardt, G; Schäfer, U | 1 |
| Gabilan, NH; Rodrigues, AL; Rosa, AO; Zeidan, MP; Zomkowski, AD | 1 |
| Fujii, T; Hayashi, K; Kobuchi, S; Matsumura, Y; Sugiura, T; Takaoka, M; Tsutsui, H | 1 |
| Chen, Y; Li, F; Li, J; Liu, Y; Lu, X; Su, R; Wu, N | 1 |
| Ali, I; Andurkar, SV; Bhalla, S; Gulati, A; Lee, H | 1 |
| Chen, MF; Cheng, JT; Chiu, NH; Chou, MT; Chung, HH; Mar, GY | 1 |
| Aglawe, MM; Chopde, CT; Kotagale, NR; Taksande, BG; Tripathi, SJ; Umekar, MJ | 1 |
| Alekseev, AE; Evdokimovskii, EV; Kokoz, YM; Maltsev, AV; Pimenov, OY; Reyes, S | 1 |
| Bernard, R; Bernstein, HG; Laube, G; Veh, RW; Weiss, T | 1 |
| Aglawe, MM; Chopde, CT; Gujar, S; Khade, SD; Kotagale, NR; Taksande, BG | 1 |
| Manole, OM; Moraru, C; Nechita, P; Rusu-Zota, G; Şorodoc, V | 1 |
1 review(s) available for efaroxan and agmatine
| Article | Year |
|---|---|
Characterization of the imidazoline binding site involved in regulation of insulin secretion.
Topics: Agmatine; Animals; Benzofurans; Down-Regulation; Imidazoles; Imidazoline Receptors; Insulin; Insulin Secretion; Islets of Langerhans; Receptors, Drug | 1995 |
17 other study(ies) available for efaroxan and agmatine
| Article | Year |
|---|---|
Synthesis and biological evaluation of new 2-(4,5-dihydro-1H-imidazol-2-yl)-3,4-dihydro-2H-1,4-benzoxazine derivatives.
Topics: Adrenal Medulla; Animals; Antihypertensive Agents; Binding Sites; Blood Pressure; Cattle; Frontal Lobe; Heart Rate; Imidazoles; Imidazoline Receptors; In Vitro Techniques; Kidney; Oxazines; Rabbits; Radioligand Assay; Rats; Rats, Inbred SHR; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Receptors, Drug; Stereoisomerism; Structure-Activity Relationship | 2003 |
Agmatine is not a good candidate as endogenous ligand for imidazoline sites of pancreatic B cells and vascular bed.
Topics: Agmatine; Animals; Benzofurans; Imidazoles; Imidazoline Receptors; Insulin; Insulin Secretion; Islets of Langerhans; Ligands; Male; Protein Binding; Rats; Rats, Wistar; Receptors, Drug | 1996 |
Elevation of cytosolic calcium by imidazolines in mouse islets of Langerhans: implications for stimulus-response coupling of insulin release.
Topics: Adrenergic alpha-Antagonists; Agmatine; Animals; Benzofurans; Calcium; Cytosol; Down-Regulation; Glucose; Idazoxan; Imidazoles; Imidazoline Receptors; Insulin; Islets of Langerhans; Mice; Phentolamine; Receptors, Drug; Signal Transduction | 1996 |
Blockade by agmatine of catecholamine release from chromaffin cells is unrelated to imidazoline receptors.
Topics: Acetylcholine; Agmatine; Animals; Benzofurans; Binding Sites; Binding, Competitive; Calcium Channels; Catecholamines; Cattle; Cells, Cultured; Chromaffin Cells; Clonidine; Dose-Response Relationship, Drug; Electric Stimulation; Imidazoles; Imidazoline Receptors; Membrane Potentials; Potassium; Potassium Channels; Receptors, Drug; Receptors, Nicotinic; Sodium Channels | 2001 |
Modification of noradrenaline release in pithed spontaneously hypertensive rats by I1-binding sites in addition to alpha2-adrenoceptors.
Topics: Adrenergic alpha-Antagonists; Agmatine; Animals; Antihypertensive Agents; Benzofurans; Binding Sites; Blood Pressure; Disease Models, Animal; Heart Rate; Idazoxan; Imidazoles; Male; Norepinephrine; Phenoxybenzamine; Rats; Rats, Inbred SHR; Receptors, Adrenergic, alpha-2 | 2003 |
Moxonidine displays a presynaptic alpha-2-adrenoceptor-dependent synergistic sympathoinhibitory action at imidazoline-1 receptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Agmatine; Animals; Benzofurans; Bridged Bicyclo Compounds; Brimonidine Tartrate; Drug Synergism; Heart; Heptanes; Imidazoles; Imidazoline Receptors; Norepinephrine; Oxazoles; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Receptors, Drug; Rilmenidine; Sympathetic Nervous System; Sympatholytics; Yohimbine | 2003 |
Norepinephrine release is reduced by I(1)-receptors in addition to alpha(2)-adrenoceptors.
Topics: Adrenergic alpha-Antagonists; Agmatine; Animals; Benzofurans; Blood Pressure; Bridged Bicyclo Compounds; Electric Stimulation; Heptanes; Hypertension; Idazoxan; Imidazoles; Imidazoline Receptors; Male; Norepinephrine; Phenoxybenzamine; Rats; Rats, Inbred SHR; Receptors, Adrenergic, alpha-2; Receptors, Drug; Spinal Cord | 2003 |
Evidence for imidazoline receptors involvement in the agmatine antidepressant-like effect in the forced swimming test.
Topics: Agmatine; Animals; Antazoline; Antidepressive Agents; Benzofurans; Clonidine; Female; Imidazoles; Imidazoline Receptors; Male; Mice; Receptors, Adrenergic, alpha-2; Receptors, Drug; Receptors, N-Methyl-D-Aspartate; Swimming | 2007 |
Preventive mechanisms of agmatine against ischemic acute kidney injury in rats.
Topics: Adrenergic alpha-2 Receptor Antagonists; Agmatine; Animals; Benzofurans; Imidazoles; Imidazoline Receptors; Kidney Diseases; Male; Norepinephrine; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Sympathetic Nervous System; Veins; Yohimbine | 2009 |
Imidazoline receptor antisera-selected/Nischarin regulates the effect of agmatine on the development of morphine dependence.
Topics: Adenosine Monophosphate; Adrenergic alpha-Antagonists; Agmatine; Animals; Benzofurans; Cells, Cultured; Drug Interactions; Gene Knockdown Techniques; Hippocampus; Imidazoles; Imidazoline Receptors; Immune Sera; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred BALB C; Morphine Dependence; Neurons; Proto-Oncogene Proteins c-fos; RNA, Small Interfering; Substance Withdrawal Syndrome | 2012 |
Potentiation of oxycodone antinociception in mice by agmatine and BMS182874 via an imidazoline I2 receptor-mediated mechanism.
Topics: Agmatine; Analgesics, Opioid; Animals; Benzofurans; Dansyl Compounds; Drug Synergism; Imidazoles; Imidazoline Receptors; Male; Mice; Oxycodone; Pain Measurement | 2013 |
Changes of imidazoline receptors in spontaneously hypertensive rats.
Topics: Agmatine; Animals; Antihypertensive Agents; Aorta, Thoracic; Benzofurans; Blood Pressure; Blotting, Western; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Hypertension; Imidazoles; Imidazoline Receptors; KATP Channels; Male; Potassium Channel Blockers; Protein Kinase Inhibitors; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Up-Regulation; Vasodilation; Vasodilator Agents | 2013 |
Evidences for the agmatine involvement in antidepressant like effect of bupropion in mouse forced swim test.
Topics: Agmatine; Animals; Antidepressive Agents; Arginine; Benzofurans; Biguanides; Bupropion; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Eflornithine; Guanidines; Idazoxan; Imidazoles; Immobility Response, Tonic; Injections, Intraventricular; Male; Mice; Motor Activity | 2013 |
Alpha-2 adrenoceptors and imidazoline receptors in cardiomyocytes mediate counterbalancing effect of agmatine on NO synthesis and intracellular calcium handling.
Topics: Adrenergic alpha-2 Receptor Agonists; Agmatine; Animals; Benzofurans; Calcium Signaling; Cells, Cultured; Imidazoles; Imidazoline Receptors; Myocytes, Cardiac; Nitric Oxide; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Adrenergic, alpha-2 | 2014 |
Agmatine modulates spontaneous activity in neurons of the rat medial habenular complex-a relevant mechanism in the pathophysiology and treatment of depression?
Topics: Action Potentials; Agmatine; Animals; Benzofurans; Depression; Female; Habenula; Humans; Idazoxan; Imidazoles; Imidazoline Receptors; Male; Middle Aged; Neurons; Rats, Wistar; Ureohydrolases | 2018 |
Agmatine Inhibits Behavioral Sensitization to Ethanol Through Imidazoline Receptors.
Topics: Agmatine; Animals; Arginine; Benzofurans; Biguanides; Central Nervous System Sensitization; Dose-Response Relationship, Drug; Drug Interactions; Ethanol; Guanidines; Idazoxan; Imidazoles; Imidazoline Receptors; Infusions, Intraventricular; Male; Mice; Microinjections; Motor Activity | 2019 |
Effects of imidazoline agents in a rat conditioned place preference model of addiction.
Topics: Agmatine; Analgesics, Opioid; Animals; Benzofurans; Conditioning, Psychological; Drug Interactions; Idazoxan; Imidazoles; Imidazoline Receptors; Male; Rats; Rats, Wistar; Time Factors; Tramadol | 2022 |