Compounds > efaroxan
Page last updated: 2024-08-25

efaroxan and 2-(2-imidazolin-2-yl)-1-phenyl-1h-indole

efaroxan has been researched along with 2-(2-imidazolin-2-yl)-1-phenyl-1h-indole in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's3 (60.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Morgan, NG; Mourtada, M; Smith, SA1
Appelskog, IB; Berggren, PO; Efendic, S; Kapelioukh, IL; Köhler, M; Yang, SN; Zaitsev, SV1
Berggren, PO; Efendic, S; Guerin, C; Mandrup-Poulsen, T; Nicotera, P; Sharoyko, V; Størling, J; Zaitsev, SV; Zaitseva, II1
Berggren, PO; Mandrup-Poulsen, T; Størling, J; Zaitsev, SV; Zaitseva, II1
Berggren, PO; Zaitsev, SV; Zaitseva, II1

Other Studies

5 other study(ies) available for efaroxan and 2-(2-imidazolin-2-yl)-1-phenyl-1h-indole

ArticleYear
Effector systems involved in the insulin secretory responses to efaroxan and RX871024 in rat islets of Langerhans.
    European journal of pharmacology, 1998, Jun-05, Volume: 350, Issue:2-3

    Topics: Adrenergic alpha-Antagonists; Animals; Benzofurans; Calcium; Calcium Channel Blockers; Cyclic AMP; Down-Regulation; Enzyme Inhibitors; Imidazoles; In Vitro Techniques; Indoles; Insulin; Insulin Secretion; Islets of Langerhans; Male; Protein Kinase C; Protein Kinase Inhibitors; Rats; Rats, Wistar

1998
Imidazoline compounds protect against interleukin 1beta-induced beta-cell apoptosis.
    Diabetes, 2001, Volume: 50 Suppl 1

    Topics: Animals; Apoptosis; Benzofurans; Calcineurin; Calcineurin Inhibitors; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gallopamil; Imidazoles; Indoles; Interleukin-1; Islets of Langerhans; Membrane Potentials; Mice; Mice, Obese; Models, Biological; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitriles; Patch-Clamp Techniques; Pyrethrins

2001
RX871024 reduces NO production but does not protect against pancreatic beta-cell death induced by proinflammatory cytokines.
    Biochemical and biophysical research communications, 2006, Sep-08, Volume: 347, Issue:4

    Topics: Animals; Benzofurans; Cell Death; Cells, Cultured; Cytokines; Imidazoles; Indoles; Insulin; Insulin Secretion; Insulin-Secreting Cells; Interferon-gamma; Interleukin-1; Mice; Mice, Obese; Nitric Oxide; Tumor Necrosis Factor-alpha

2006
The imidazoline RX871024 induces death of proliferating insulin-secreting cells by activation of c-jun N-terminal kinase.
    Cellular and molecular life sciences : CMLS, 2008, Volume: 65, Issue:7-8

    Topics: Animals; Benzofurans; Caspases; Cell Death; Cell Line; Cell Proliferation; Cytokines; Enzyme Activation; Humans; Imidazoles; Indoles; Insulin-Secreting Cells; JNK Mitogen-Activated Protein Kinases; Mice; Nitric Oxide

2008
Insulinotropic compounds decrease endothelial cell survival.
    Toxicology in vitro : an international journal published in association with BIBRA, 2016, Volume: 33

    Topics: Benzofurans; Carbamates; Cell Proliferation; Cell Survival; Cells, Cultured; Dimethyl Sulfoxide; Glucose; Glyburide; Human Umbilical Vein Endothelial Cells; Humans; Hypoglycemic Agents; Imidazoles; Indoles; Nitric Oxide; Piperidines; Vascular Endothelial Growth Factor A

2016