edrophonium has been researched along with tacrine in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (23.53) | 18.7374 |
| 1990's | 7 (41.18) | 18.2507 |
| 2000's | 3 (17.65) | 29.6817 |
| 2010's | 3 (17.65) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Al-Rashid, ZF; Beri, V; Cheung, J; Rosenberry, TL; Shiomi, K; Wildman, SA | 1 |
| Davis, M; Jones, CR | 1 |
| Hodge, AS; Humphrey, DR; Rosenberry, TL | 1 |
| Sellin, LC; Tågerud, S; Thesleff, S | 1 |
| Cherkin, A; Flood, JF; Smith, GE | 2 |
| Axelsen, P; Harel, M; Raves, M; Silman, I; Sussman, JL | 1 |
| Harel, M; Silman, I; Sussman, JL | 1 |
| Axelsen, PH; Bouet, F; Ehret-Sabatier, L; Goeldner, M; Harel, M; Hirth, C; Schalk, I; Silman, I; Sussman, JL | 1 |
| Dowling, MH; Paddle, BM | 1 |
| Aldunate, R; Inestrosa, NC; Muñoz, FJ | 1 |
| Ariel, N; Barak, D; Kaplan, D; Kronman, C; Ordentlich, A; Shafferman, A; Velan, B | 1 |
| DYRBERG, V; HOUGS, W; JOHANSEN, SH | 1 |
| Rakonczay, Z | 1 |
| Carroll, AD; Chen, Y; Ruzicka, J; Scampavia, L | 1 |
| Draczkowski, P; Halczuk, P; Jozwiak, K; Matosiuk, D; Strzemski, M; Tomaszuk, A | 1 |
| Bartolini, M; Fabini, E; Tramarin, A | 1 |
1 review(s) available for edrophonium and tacrine
| Article | Year |
|---|---|
Three-dimensional structures of acetylcholinesterase and of its complexes with anticholinesterase agents.
Topics: Acetylcholinesterase; Animals; Binding Sites; Cholinesterase Inhibitors; Decamethonium Compounds; Edrophonium; Electrochemistry; In Vitro Techniques; Macromolecular Substances; Models, Molecular; Molecular Structure; Protein Conformation; Tacrine | 1994 |
16 other study(ies) available for edrophonium and tacrine
| Article | Year |
|---|---|
The natural product dihydrotanshinone I provides a prototype for uncharged inhibitors that bind specifically to the acetylcholinesterase peripheral site with nanomolar affinity.
Topics: Acetylcholine; Acetylcholinesterase; Aflatoxin B1; Binding Sites; Binding, Competitive; Catalysis; Catalytic Domain; Cholinesterase Inhibitors; Crystallography, X-Ray; Furans; Humans; Hydrolysis; Kinetics; Models, Chemical; Phenanthrenes; Pyrans; Quinones; Recombinant Proteins; Structure-Activity Relationship; Substrate Specificity | 2013 |
Letter: Replacement drug for edrophonium bromide.
Topics: Acridines; Adult; Cholinesterase Inhibitors; Edrophonium; Female; Humans; Myasthenia Gravis; Quaternary Ammonium Compounds; Tacrine | 1975 |
Ambenonium is a rapidly reversible noncovalent inhibitor of acetylcholinesterase, with one of the highest known affinities.
Topics: Acetylcholinesterase; Ambenonium Chloride; Cholinesterase Inhibitors; Edrophonium; Erythrocytes; Humans; Kinetics; Mathematics; Models, Theoretical; Molecular Structure; Tacrine | 1992 |
Tetrahydroaminoacridine (tacrine) stimulates neurosecretion at mammalian motor endplates.
Topics: Acetylcholine; Aminoacridines; Aminoquinolines; Animals; Botulinum Toxins; Edrophonium; Electrophysiology; Exocytosis; In Vitro Techniques; Male; Membrane Potentials; Mice; Motor Endplate; Neuromuscular Junction; Phrenic Nerve; Respiratory Muscles; Synaptic Vesicles; Tacrine; Temperature | 1990 |
Two-drug combinations of memory enhancers: effect of dose ratio upon potency and therapeutic window, in mice.
Topics: Animals; Arecoline; Drug Combinations; Drug Interactions; Edrophonium; Male; Memory; Mice; Oxotremorine; Parasympathomimetics; Tacrine | 1988 |
Memory enhancement: supra-additive effect of subcutaneous cholinergic drug combinations in mice.
Topics: Animals; Arecoline; Drug Synergism; Edrophonium; Injections, Subcutaneous; Male; Memory; Mice; Oxotremorine; Parasympathomimetics; Tacrine | 1985 |
Three-dimensional structure of acetylcholinesterase and of its complexes with anticholinesterase drugs.
Topics: Acetylcholinesterase; Animals; Binding Sites; Edrophonium; Protein Conformation; Tacrine; Torpedo; X-Ray Diffraction | 1993 |
Quaternary ligand binding to aromatic residues in the active-site gorge of acetylcholinesterase.
Topics: Acetylcholine; Acetylcholinesterase; Affinity Labels; Amino Acid Sequence; Animals; Binding Sites; Chromatography, High Pressure Liquid; Crystallography, X-Ray; Decamethonium Compounds; Edrophonium; Hydrogen Bonding; Ligands; Peptide Fragments; Protein Conformation; Protein Structure, Secondary; Quaternary Ammonium Compounds; Tacrine; Torpedo | 1993 |
Blockade of cardiac nicotinic responses by anticholinesterases.
Topics: Acetylcholine; Animals; Atropine; Carbamates; Catecholamines; Cholinesterase Inhibitors; Edrophonium; Female; Guinea Pigs; Heart; Heart Atria; Heart Rate; In Vitro Techniques; Myocardial Contraction; Nicotine; Nicotinic Antagonists; Soman; Tacrine | 1996 |
Peripheral binding site is involved in the neurotrophic activity of acetylcholinesterase.
Topics: Acetylcholinesterase; Animals; Binding Sites; Cell Division; Cells, Cultured; Cholinesterase Inhibitors; DNA; Dose-Response Relationship, Drug; Edrophonium; Formazans; Gallamine Triethiodide; Nerve Growth Factors; Neurites; Neurons; PC12 Cells; Propidium; Protein Structure, Tertiary; Rats; Spinal Cord; Tacrine; Tetrazolium Salts | 1999 |
Does "butyrylization" of acetylcholinesterase through substitution of the six divergent aromatic amino acids in the active center gorge generate an enzyme mimic of butyrylcholinesterase?
Topics: Acetylcholinesterase; Amino Acid Substitution; Benzenaminium, 4,4'-(3-oxo-1,5-pentanediyl)bis(N,N-dimethyl-N-2-propenyl-), Dibromide; Binding Sites; Butyrates; Butyrylcholinesterase; Cholinesterase Inhibitors; Decamethonium Compounds; Edrophonium; Humans; Hydrolysis; Kinetics; Ligands; Molecular Mimicry; Mutagenesis, Site-Directed; Organophosphorus Compounds; Substrate Specificity; Tacrine | 2001 |
Hydroaminacrine. I. Its influence on the interaction of edrophonium and suxamethonium.
Topics: Acridines; Edrophonium; Leadership; Succinylcholine; Tacrine | 1962 |
Potencies and selectivities of inhibitors of acetylcholinesterase and its molecular forms in normal and Alzheimer's disease brain.
Topics: Acetylcholinesterase; Alzheimer Disease; Benzazepines; Brain; Butyrylcholinesterase; Carbamates; Cerebral Cortex; Cholinesterase Inhibitors; Edrophonium; Humans; In Vitro Techniques; Phenylcarbamates; Physostigmine; Rivastigmine; Tacrine; Trichlorfon | 2003 |
Automated method, based on micro-sequential injection, for the study of enzyme kinetics and inhibition.
Topics: Acetylcholinesterase; Autoanalysis; Dipeptides; Dose-Response Relationship, Drug; Edrophonium; Flow Injection Analysis; Kinetics; Microchemistry; Peptidyl-Dipeptidase A; Sensitivity and Specificity; Syringes; Tacrine; Time Factors | 2006 |
Determination of affinity and efficacy of acetylcholinesterase inhibitors using isothermal titration calorimetry.
Topics: Acetylcholine; Acetylcholinesterase; Ambenonium Chloride; Animals; Calorimetry; Cholinesterase Inhibitors; Donepezil; Edrophonium; Electrophorus; Fish Proteins; Galantamine; Indans; Kinetics; Piperidines; Tacrine; Thermodynamics | 2016 |
Combination of human acetylcholinesterase and serum albumin sensing surfaces as highly informative analytical tool for inhibitor screening.
Topics: Acetylcholinesterase; Cholinesterase Inhibitors; Donepezil; Edrophonium; Enzymes, Immobilized; Galantamine; Humans; Indans; Kinetics; Ligands; Piperidines; Recombinant Fusion Proteins; Serum Albumin; Surface Plasmon Resonance; Tacrine | 2018 |