Page last updated: 2024-08-17

edetic acid and succimer

edetic acid has been researched along with succimer in 74 studies

Research

Studies (74)

Timeframe	Studies, this research(%)	All Research%
pre-1990	16 (21.62)	18.7374
1990's	31 (41.89)	18.2507
2000's	17 (22.97)	29.6817
2010's	9 (12.16)	24.3611
2020's	1 (1.35)	2.80

Authors

Authors	Studies
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Dragovic, D; Friedheim, E; Graziano, JH; Kaul, B; Popovac, D	1
Graziano, JH; Lolacono, NJ; Mitchell, ME; Moulton, T; Slavkovich, V; Zarate, C	1
Bauchner, H; Glotzer, DE	1
Chisolm, JJ	2
Kosnett, MJ	1
Braithwaite, RA; Ching, GW; Rogers, SM; Vale, JA	1
Flora, SJ; Tandon, SK	1
Abril Mendez, O; Farga Marti, A; Galvez Alvarez, J; Garcia Domenech, R	1
Dhawan, M; Flora, SJ; Singh, S; Tandon, SK	1
Basinger, MA; Holscher, MA; Jones, MM; Vaughn, WK	1
Corbella, J; Domingo, JL; Llobet, JM	1
Graziano, JH; Lolacono, NJ; Meyer, P	1
Goering, PL; Klaassen, CD; Tandon, SK	1
Bankowska, J; Hine, C	1
Flora, SJ; Singh, S; Tandon, SK	1
Behar, R; Bentur, Y; Brook, JG; Taitelman, U	1
Kolton, L; Yaari, Y	1
Cantilena, LR; Klaassen, CD; Stacey, NH	1
Cantilena, LR; Klaassen, CD	3
Galvez Alvarez, J; Garcia Domenech, R; Garcia Muñoz, M; Moreno Frigols, J	1
Flora, GJ; Mathur, R; Prakash, AO; Seth, PK	1
Bhattacharya, R; Flora, SJ; Vijayaraghavan, R	1
Ahn, KD; Lee, BK; Schwartz, BS; Stewart, W	1
Aposhian, HV; Aposhian, MM; Dart, RC; Gonzalez-Ramirez, D; Hurlbut, KM; Junco-Munoz, P; Maiorino, RM; Xu, Z; Zuniga-Charles, M	1
Ham, HR; Piepsz, A; Pintelon, H	1
Brown, H; Cosgriff, P; Peters, AM	1
Atkins, LM; Basinger, MA; Gale, GR; Jones, MM; Smith, AB; Stone, A	1
Hermes-Lima, M; Storey, KB	1
Jorgensen, FM	1
Mortensen, ME; Walson, PD	1
Funakoshi, T; Kojima, S; Shimada, H; Xie, J	1
Cherian, MG; Goyer, RA; Jones, MM; Reigart, JR	1
Bernal, J; Ruvalcaba, S	1
Aposhian, HV; Fernando, Q; Gandolfi, AJ; Keith, RL; Setiarahardjo, I	1
Flora, SJ; Kannan, GM; Kumar, P; Sachan, AS	1
Anderson, RL; Besunder, JB; Super, DM	1
Bernal, J; Cribbs, LL; Lee, JH; Perez-Reyes, E	1
Berger, O; Bhattacharya, A; Medvedovic, M; Shukla, R; Smelser, DT	1
Mathur, N; Prasad, S; Singh, S; Tandon, SK	1
Amin, Z; Gordon, RA; Paloucek, FP; Roberts, G; Williams, RH	1
Lever, SZ; Parsons, TL	1
el-Refai, NY; Hottel, TL; Jones, JJ	1
Arora, U; Flora, GJ; Seth, PK	1
Denver, MC; Galey, FD; Kass, PH; Tell, LA; Trupkiewicz, JG	1
Chambers-Emerson, J; Dethlefsen, M; McNutt, TK; Shah, R	1
Horowitz, BZ; Mirkin, DB	1
Bennett, PN; Gordon, JN; Taylor, A	1
Makkar, S; Singh, V; Vineeta, N	1
Ko, KW; Meldrum, JB	1
Lever, SZ; Zhu, X	1
DeLaune, RD; Fukushi, K; Jugsujinda, A; Parkpian, P; Wongkongkatep, J	1
Flora, SJ; Saxena, G	1
Brent, RL; Florin, TA; Weitzman, M	1
Brown, MJ; Leiker, R; Omalu, B; Willis, T	1
Flora, SJ; Mehta, A; Saxena, G	1
Auyang, ED; Bhattacharya, A; Bornschein, R; Dietrich, KN; Shukla, R	1
Wang, L	1
Chomchai, C; Hussain, J; McCullough, L; Petranovic, M; Woolf, AD	1
Hjelmhaug, J; Lobner, D; Rush, T	1
Bradberry, S; Vale, A	1
Guzzi, G; Minoia, C; Pigatto, P; Ronchi, A	1
Crinnion, WJ	1
Cardellach, F; Domínguez, V; Fernández, S; Nogué, S; Pollio, GA; Torra, M	1
Bradford, KK; Gorman, K; Lercher, D; Permar, S	1
Emery, LC; Greenacre, C; Hecht, S; Jones, M; Morandi, F	1
Aaseth, J; Bjørklund, G; Mutter, J	1
Abu-Dari, KI; Ata, SA; Mubarak, MS; Tutunji, MF	1
Gresham, C; Hsiao, CY; Marshall, MR	1
Miller, CA; Zhang, YV	1

Reviews

11 review(s) available for edetic acid and succimer

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Unanswered questions in metal chelation. Journal of toxicology. Clinical toxicology, 1992, Volume: 30, Issue:4 Topics: Animals; Arsenic Poisoning; Chelating Agents; Chelation Therapy; Dimercaprol; Edetic Acid; Humans; Lead Poisoning; Mercury Poisoning; Poisoning; Succimer	1992
Evaluation of the potential role of chelation therapy in treatment of low to moderate lead exposures. Environmental health perspectives, 1990, Volume: 89 Topics: Animals; Chelating Agents; Chelation Therapy; Drug Evaluation; Edetic Acid; Humans; Lead; Lead Poisoning; Succimer	1990
Mobilization of heavy metals by newer, therapeutically useful chelating agents. Toxicology, 1995, Mar-31, Volume: 97, Issue:1-3 Topics: Animals; Chelating Agents; Dimercaprol; Edetic Acid; Humans; Metals; Succimer; Unithiol	1995
Succimer: the first approved oral lead chelator. American family physician, 1993, Volume: 48, Issue:8 Topics: Administration, Oral; Ambulatory Care; Clinical Trials as Topic; Drug Costs; Drug Eruptions; Drug Monitoring; Edetic Acid; Female; Gastrointestinal Diseases; Humans; Lead Poisoning; Mass Screening; Metabolic Clearance Rate; Neutropenia; Pregnancy; Succimer; Transaminases; United States; United States Food and Drug Administration	1993
Chelation therapy for childhood lead poisoning. The changing scene in the 1990s. Clinical pediatrics, 1993, Volume: 32, Issue:5 Topics: Chelation Therapy; Child; Dimercaprol; Edetic Acid; Humans; Lead; Lead Poisoning; Penicillamine; Succimer	1993
Aggressive approach in the treatment of acute lead encephalopathy with an extraordinarily high concentration of lead. Archives of pediatrics & adolescent medicine, 1998, Volume: 152, Issue:11 Topics: Brain Diseases; Child, Preschool; Dimercaprol; Edetic Acid; Environmental Exposure; Female; Humans; Iron Chelating Agents; Lead; Lead Poisoning; Paint; Polyethylene Glycols; Succimer; Therapeutic Irrigation	1998
[Childhood lead poisoning (Part B)]. Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2007, Volume: 9, Issue:6 Topics: Child; Edetic Acid; Environmental Pollution; Health Education; Humans; Lead Poisoning; Penicillamine; Succimer	2007
A comparison of sodium calcium edetate (edetate calcium disodium) and succimer (DMSA) in the treatment of inorganic lead poisoning. Clinical toxicology (Philadelphia, Pa.), 2009, Volume: 47, Issue:9 Topics: Administration, Oral; Animals; Antidotes; Chelating Agents; Clinical Trials as Topic; Edetic Acid; Humans; Lead; Lead Poisoning; Succimer	2009
Metal chelators and neurotoxicity: lead, mercury, and arsenic. Archives of toxicology, 2017, Volume: 91, Issue:12 Topics: Arsenic Poisoning; Chelating Agents; Edetic Acid; Humans; Lead Poisoning, Nervous System; Mercury Poisoning, Nervous System; Monensin; Succimer; Unithiol	2017
Treatment of lead and arsenic poisoning in anuric patients - a case report and narrative review of the literature. BMC nephrology, 2019, 10-17, Volume: 20, Issue:1 Topics: Adult; Animals; Anuria; Arsenic Poisoning; Chelating Agents; Continuous Renal Replacement Therapy; Dimercaprol; Edetic Acid; Humans; Kidney Failure, Chronic; Lead Poisoning; Male; Renal Dialysis; Succimer; Unithiol	2019

Trials

5 trial(s) available for edetic acid and succimer

Article	Year
Controlled study of meso-2,3-dimercaptosuccinic acid for the management of childhood lead intoxication. The Journal of pediatrics, 1992, Volume: 120, Issue:1 Topics: Administration, Oral; Ambulatory Care; Aminolevulinic Acid; Calcium; Chelating Agents; Child; Child, Preschool; Dimercaprol; Edetic Acid; Erythrocytes; Follow-Up Studies; Humans; Infant; Injections, Intravenous; Lead; Lead Poisoning; Porphobilinogen Synthase; Safety; Succimer; Zinc	1992
Dose-response study of oral 2,3-dimercaptosuccinic acid in children with elevated blood lead concentrations. The Journal of pediatrics, 1988, Volume: 113, Issue:4 Topics: Administration, Oral; Child; Child, Preschool; Drug Administration Schedule; Edetic Acid; Humans; Lead Poisoning; Minerals; Random Allocation; Sensitivity and Specificity; Succimer; Sulfhydryl Compounds	1988
Provocative chelation with DMSA and EDTA: evidence for differential access to lead storage sites. Occupational and environmental medicine, 1995, Volume: 52, Issue:1 Topics: Adult; Chelation Therapy; Dose-Response Relationship, Drug; Edetic Acid; Environmental Monitoring; Humans; Korea; Lead; Male; Middle Aged; Occupational Exposure; Succimer; Time Factors	1995
Effects of calcium disodium EDTA and meso-2,3-dimercaptosuccinic acid on tissue concentrations of lead for use in treatment of calves with experimentally induced lead toxicosis. American journal of veterinary research, 2003, Volume: 64, Issue:6 Topics: Animals; Bone and Bones; Brain Chemistry; Cattle; Chelating Agents; Drug Therapy, Combination; Edetic Acid; Kidney; Lead; Lead Poisoning; Liver; Male; Muscle, Skeletal; Succimer; Testis	2003
Effect of succimer chelation therapy on postural balance and gait outcomes in children with early exposure to environmental lead. Neurotoxicology, 2007, Volume: 28, Issue:3 Topics: Cerebellum; Chelating Agents; Child, Preschool; Cohort Studies; Edetic Acid; Environmental Exposure; Female; Gait; Humans; Infant; Lead; Lead Poisoning, Nervous System, Childhood; Male; Mechanoreceptors; Neural Pathways; Postural Balance; Psychomotor Performance; Socioeconomic Factors; Succimer; Vestibule, Labyrinth	2007

Other Studies

58 other study(ies) available for edetic acid and succimer

Article	Year
Treatment of lead poisoning by 2,3-dimercaptosuccinic acid. Lancet (London, England), 1978, Dec-09, Volume: 2, Issue:8102 Topics: Administration, Oral; Adult; Chemical Phenomena; Chemistry; Drug Administration Schedule; Drug Evaluation; Edetic Acid; Humans; Injections, Intravenous; Lead; Lead Poisoning; Metallurgy; Middle Aged; Succimer; Sulfhydryl Compounds	1978
Management of childhood lead poisoning: a survey. Pediatrics, 1992, Volume: 89, Issue:4 Pt 1 Topics: Chelating Agents; Child; Clinical Protocols; Drug Utilization; Edetic Acid; Humans; Lead; Lead Poisoning; Penicillamine; Succimer; United States	1992
BAL, EDTA, DMSA and DMPS in the treatment of lead poisoning in children. Journal of toxicology. Clinical toxicology, 1992, Volume: 30, Issue:4 Topics: Administration, Oral; Beverages; Chelation Therapy; Child; Child, Preschool; Dimercaprol; Edetic Acid; Female; Housing; Humans; Infant; Lead; Lead Poisoning; Male; Penicillamine; Succimer; Unithiol	1992
An oral treatment for lead toxicity. Postgraduate medical journal, 1991, Volume: 67, Issue:792 Topics: Edetic Acid; Humans; Lead Poisoning; Succimer	1991
Beneficial effects of zinc supplementation during chelation treatment of lead intoxication in rats. Toxicology, 1990, Volume: 64, Issue:2 Topics: Acetates; Acetic Acid; Administration, Oral; Aminolevulinic Acid; Animals; Chelation Therapy; Drug Therapy, Combination; Edetic Acid; Lead; Lead Poisoning; Male; Penicillamine; Porphobilinogen Synthase; Protoporphyrins; Rats; Succimer	1990
Physico-chemical study of the radiopharmaceuticals 99mTc-DMSA, 99mTc-EDTA and 99mTc-DTPA interaction with plasmatic proteins. International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes, 1989, Volume: 40, Issue:6 Topics: Blood Proteins; Edetic Acid; Organotechnetium Compounds; Pentetic Acid; Protein Binding; Succimer; Sulfhydryl Compounds; Technetium; Technetium Tc 99m Dimercaptosuccinic Acid; Technetium Tc 99m Pentetate	1989
Chelation of lead during co-exposure to ethanol. Biochemistry international, 1989, Volume: 19, Issue:5 Topics: Acrylates; Animals; Chelating Agents; Edetic Acid; Ethanol; Lead; Lead Poisoning; Male; Penicillamine; Rats; Succimer; Sulfhydryl Compounds	1989
Antagonists for acute oral cadmium chloride intoxication. Journal of toxicology and environmental health, 1988, Volume: 23, Issue:1 Topics: Administration, Oral; Animals; Antidotes; Cadmium; Cadmium Chloride; Cadmium Poisoning; Chelating Agents; Edetic Acid; Male; Mice; Pentetic Acid; Succimer	1988
Comparative effects of repeated parenteral administration of several chelators on the distribution and excretion of cobalt. Research communications in chemical pathology and pharmacology, 1988, Volume: 60, Issue:2 Topics: Acetylcysteine; Animals; Chelating Agents; Cobalt; Edetic Acid; Glutathione; Injections, Intraperitoneal; Male; Pentetic Acid; Rats; Rats, Inbred Strains; Succimer	1988
Induction of hepatic metallothionein in mouse liver following administration of chelating agents. Toxicology and applied pharmacology, 1985, Sep-30, Volume: 80, Issue:3 Topics: Animals; Chelating Agents; Dimercaprol; Ditiocarb; Edetic Acid; Liver; Male; Metallothionein; Mice; Nitrilotriacetic Acid; Penicillamine; Pentetic Acid; Succimer	1985
Retention of lead in the rat. Archives of environmental contamination and toxicology, 1985, Volume: 14, Issue:5 Topics: Animals; Chelating Agents; Diet; Edetic Acid; Lead; Male; Rats; Rats, Inbred Strains; Succimer	1985
Chelation in metal intoxication XXI: Chelation in lead intoxication during vitamin B complex deficiency. Bulletin of environmental contamination and toxicology, 1986, Volume: 37, Issue:3 Topics: Aminolevulinic Acid; Animals; Body Burden; Chelating Agents; Edetic Acid; Lead; Lead Poisoning; Male; Rats; Succimer; Vitamin B Deficiency	1986
Meso-2,3-dimercaptosuccinic acid in the diagnosis and treatment of lead poisoning. Journal of toxicology. Clinical toxicology, 1987, Volume: 25, Issue:1-2 Topics: Adult; Bread; Edetic Acid; Food Contamination; Humans; Lead; Lead Poisoning; Male; Succimer; Sulfhydryl Compounds	1987
Sites of action of lead on spontaneous transmitter release from motor nerve terminals. Israel journal of medical sciences, 1982, Volume: 18, Issue:1 Topics: Animals; Calcium; Cell Membrane Permeability; Edetic Acid; In Vitro Techniques; Lead; Membrane Potentials; Motor Endplate; Neuromuscular Junction; Neurotransmitter Agents; Rana ridibunda; Succimer	1982
Cadmium toxicity and lipid peroxidation in isolated rat hepatocytes. Toxicology and applied pharmacology, 1980, Volume: 53, Issue:3 Topics: Adenosine Triphosphatases; Animals; Antioxidants; Aspartate Aminotransferases; Cadmium; Cell Membrane; Ditiocarb; Dose-Response Relationship, Drug; Edetic Acid; In Vitro Techniques; Lactates; Lipid Peroxides; Liver; Male; Nitrilotriacetic Acid; Pentetic Acid; Potassium; Pyruvates; Rats; Sodium Salicylate; Succimer; Time Factors	1980
Comparison of the effectiveness of several chelators after single administration on the toxicity, excretion, and distribution of cadmium. Toxicology and applied pharmacology, 1981, Volume: 58, Issue:3 Topics: Animals; Cadmium; Cadmium Poisoning; Chelating Agents; Edetic Acid; Male; Mice; Pentetic Acid; Succimer; Tissue Distribution	1981
Decreased effectiveness of chelation therapy with time after acute cadmium poisoning. Toxicology and applied pharmacology, 1982, Volume: 63, Issue:2 Topics: Acute Disease; Animals; Cadmium; Cadmium Poisoning; Chelating Agents; Edetic Acid; Liver; Male; Metallothionein; Mice; Mice, Inbred Strains; Pentetic Acid; Succimer; Time Factors	1982
The effect of chelating agents on the excretion of endogenous metals. Toxicology and applied pharmacology, 1982, Volume: 63, Issue:3 Topics: Animals; Chelating Agents; Copper; Edetic Acid; Iron; Magnesium; Male; Manganese; Metals; Mice; Mice, Inbred Strains; Penicillamine; Pentetic Acid; Succimer; Zinc	1982
Stability of the radiopharmaceutical [99mTc]DMSA: study of the ligand exchange reaction with [99Tc]EDTA. The International journal of applied radiation and isotopes, 1983, Volume: 34, Issue:11 Topics: Drug Stability; Edetic Acid; Hydrogen-Ion Concentration; Ligands; Organotechnetium Compounds; Succimer; Sulfhydryl Compounds; Technetium; Technetium Tc 99m Dimercaptosuccinic Acid; Temperature	1983
Treatment guidelines for lead exposure in children. American Academy of Pediatrics Committee on Drugs. Pediatrics, 1995, Volume: 96, Issue:1 Pt 1 Topics: Chelating Agents; Child; Dimercaprol; Edetic Acid; Humans; Lead Poisoning; Penicillamine; Succimer	1995
Therapeutic efficacy of combined meso 2,3-dimercaptosuccinic acid and calcium disodium edetate treatment during acute lead intoxication in rats. Human & experimental toxicology, 1995, Volume: 14, Issue:5 Topics: Alanine Transaminase; Alkaline Phosphatase; Aminolevulinic Acid; Animals; Aspartate Aminotransferases; Drug Therapy, Combination; Edetic Acid; Glutathione; Hemoglobins; Kidney; Lead; Lead Poisoning; Liver; Male; Porphobilinogen Synthase; Proteinuria; Rats; Succimer	1995
Combined therapeutic potential of meso-2,3-dimercaptosuccinic acid and calcium disodium edetate on the mobilization and distribution of lead in experimental lead intoxication in rats. Fundamental and applied toxicology : official journal of the Society of Toxicology, 1995, Volume: 25, Issue:2 Topics: Alkaline Phosphatase; Animals; Brain Chemistry; Copper; Drug Therapy, Combination; Edetic Acid; Femur; Kidney; Lead; Lead Poisoning; Liver; Male; Rats; Rats, Wistar; Succimer; Transaminases; Zinc	1995
Estimation of normal chromium-51 ethylene diamine tetra-acetic acid clearance in children. European journal of nuclear medicine, 1994, Volume: 21, Issue:1 Topics: Adolescent; Child; Child, Preschool; Chromium Radioisotopes; Edetic Acid; Female; Glomerular Filtration Rate; Humans; Infant; Kidney; Male; Organotechnetium Compounds; Radioisotope Renography; Reference Values; Succimer; Technetium Tc 99m Dimercaptosuccinic Acid; Urinary Tract Infections	1994
Measurement of the extravascular concentration of renal agents following intravenous bolus injection. Nuclear medicine communications, 1994, Volume: 15, Issue:2 Topics: Adult; Child, Preschool; Edetic Acid; Humans; Injections, Intravenous; Iodine Radioisotopes; Iodohippuric Acid; Kidney; Organotechnetium Compounds; Radionuclide Imaging; Succimer; Technetium Tc 99m Dimercaptosuccinic Acid; Technetium Tc 99m Mertiatide	1994
Effect of chelate treatments on kidney, bone and brain lead levels of lead-intoxicated mice. Toxicology, 1994, Apr-18, Volume: 89, Issue:2 Topics: Animals; Bone and Bones; Brain; Brain Chemistry; Chelating Agents; Edetic Acid; Injections, Intraperitoneal; Kidney; Lead; Lead Poisoning; Mice; Pentetic Acid; Spectrophotometry, Atomic; Succimer	1994
In vitro oxidative inactivation of glutathione S-transferase from a freeze tolerant reptile. Molecular and cellular biochemistry, 1993, Jul-21, Volume: 124, Issue:2 Topics: Adaptation, Physiological; Animals; Azides; Catalase; Colubridae; Edetic Acid; Enzyme Activation; Free Radicals; Freezing; Glutathione Transferase; Mercaptoethanol; Muscle Proteins; Oxidation-Reduction; Reactive Oxygen Species; Sodium Azide; Succimer	1993
Effects of chelating agents on testicular toxicity in mice caused by acute exposure to nickel. Toxicology, 1995, Dec-10, Volume: 103, Issue:3 Topics: Animals; Chelating Agents; Ditiocarb; Dose-Response Relationship, Drug; Edetic Acid; Female; Fertility; Kidney; Lethal Dose 50; Lipid Peroxidation; Liver; Male; Metals; Mice; Mice, Inbred ICR; Nickel; Organ Size; Sorbitol; Succimer; Testis; Thiocarbamates	1995
Role of chelating agents for prevention, intervention, and treatment of exposures to toxic metals. Environmental health perspectives, 1995, Volume: 103, Issue:11 Topics: Chelating Agents; Chelation Therapy; Edetic Acid; Humans; Lead; Mercury; Penicillamine; Succimer	1995
Pharmacological prevention of acute lead poisoning in Paramecium. Toxicology, 1996, Apr-30, Volume: 108, Issue:3 Topics: Animals; Antidotes; Ascorbic Acid; Cations, Divalent; Cell Membrane; Chelating Agents; Cilia; Edetic Acid; Lead; Paramecium; Succimer; Sulfonamides; Swimming; Time Factors	1996
Utilization of renal slices to evaluate the efficacy of chelating agents for removing mercury from the kidney. Toxicology, 1997, Jan-15, Volume: 116, Issue:1-3 Topics: Animals; Antidotes; Chelating Agents; Dithiothreitol; Drug Evaluation, Preclinical; Edetic Acid; Evaluation Studies as Topic; Glutathione; Kidney; Male; Mercuric Chloride; Mercury; Penicillamine; Rabbits; Succimer; Thioctic Acid; Unithiol	1997
Effects of chelation therapy on hepatic glutathione, lipid peroxidation and phospholipid contents in lead-poisoned rats. Indian journal of physiology and pharmacology, 1996, Volume: 40, Issue:2 Topics: Animals; Chelating Agents; Chelation Therapy; Edetic Acid; Glutathione; Lead Poisoning; Lipid Peroxidation; Liver; Male; Malondialdehyde; Phospholipids; Rats; Succimer	1996
Comparison of dimercaptosuccinic acid and calcium disodium ethylenediaminetetraacetic acid versus dimercaptopropanol and ethylenediaminetetraacetic acid in children with lead poisoning. The Journal of pediatrics, 1997, Volume: 130, Issue:6 Topics: Alanine Transaminase; Blood Urea Nitrogen; Child; Child, Preschool; Creatinine; Edetic Acid; Female; Hemoglobins; Humans; Lead Poisoning; Male; Retrospective Studies; Succimer; Vomiting	1997
Full reversal of Pb++ block of L-type Ca++ channels requires treatment with heavy metal antidotes. The Journal of pharmacology and experimental therapeutics, 1997, Volume: 282, Issue:1 Topics: Animals; Antidotes; Calcium Channel Blockers; Dose-Response Relationship, Drug; Edetic Acid; Humans; Lead; Rabbits; Succimer; Xenopus laevis	1997
The effect of succimer therapy in lead intoxication using postural balance as a measure: a case study in a nine year old child. Neurotoxicology, 1998, Volume: 19, Issue:1 Topics: Administration, Oral; Child; Dimercaprol; Drug Administration Schedule; Edetic Acid; Humans; Lead Poisoning; Male; Patient Compliance; Postural Balance; Succimer	1998
Mobilization of lead by calcium versenate and dimercaptosuccinate in the rat. Clinical and experimental pharmacology & physiology, 1998, Volume: 25, Issue:9 Topics: Animals; Body Burden; Bone and Bones; Brain; Calcium; Chelating Agents; Edetic Acid; Iron; Lead; Male; Rats; Succimer; Zinc	1998
The presence of lead decreases the availability of meso-2, 3-dimercaptosuccinic acid for analysis in the monobromobimane assay. Chemical research in toxicology, 1999, Volume: 12, Issue:11 Topics: Bridged Bicyclo Compounds; Chelating Agents; Chromatography, High Pressure Liquid; Dithiothreitol; Edetic Acid; Lead; Organometallic Compounds; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Succimer; Sulfhydryl Compounds; Sulfhydryl Reagents	1999
A comparison of the effects of three chelating agents on the root canals of extracted human teeth. Journal of endodontics, 1999, Volume: 25, Issue:11 Topics: Chelating Agents; Dental Pulp Cavity; Dentin; Dentin Permeability; Edetic Acid; Humans; Smear Layer; Succimer; Trientine	1999
Influence of combined therapeutic potential of meso 2,3-dimercaptosuccinic acid and calcium disodium edetate on lead-induced testicular alterations in rats. Biomedical and environmental sciences : BES, 1999, Volume: 12, Issue:4 Topics: Animals; Chelating Agents; Edetic Acid; Lead; Male; Rats; Succimer; Testicular Neoplasms; Testis	1999
Comparison of two heavy metal chelators for treatment of lead toxicosis in cockatiels. American journal of veterinary research, 2000, Volume: 61, Issue:8 Topics: Animals; Bird Diseases; Body Weight; Chelating Agents; Edetic Acid; Female; Kidney; Lead; Lead Poisoning; Liver; Male; Psittaciformes; Random Allocation; Spectrophotometry, Atomic; Spleen; Succimer; Survival Analysis; Thyroid Gland	2000
Bite the bullet: lead poisoning after ingestion of 206 lead bullets. Veterinary and human toxicology, 2001, Volume: 43, Issue:5 Topics: Antidotes; Chelating Agents; Colon; Edetic Acid; Foreign Bodies; Gastrointestinal Hemorrhage; Humans; Lead; Lead Poisoning; Male; Middle Aged; Schizophrenia; Succimer; Suicide, Attempted; Therapeutic Irrigation; Treatment Outcome	2001
Lead poisoning and chelation in a mother-neonate pair. Journal of toxicology. Clinical toxicology, 2001, Volume: 39, Issue:7 Topics: Adult; Chelating Agents; Chelation Therapy; Dimercaprol; Edetic Acid; Female; Fetal Blood; Humans; Infant, Newborn; Lead Poisoning; Maternal-Fetal Exchange; Pregnancy; Pregnancy Complications; Pregnancy Trimester, Third; Succimer	2001
Lead poisoning: case studies. British journal of clinical pharmacology, 2002, Volume: 53, Issue:5 Topics: Acute Disease; Adult; Chelating Agents; Edetic Acid; Humans; Lead; Lead Poisoning; Male; Middle Aged; Occupational Diseases; Succimer	2002
Anti microbial activity of dimercaptosuccinic acid (DMSA): a new chelating agent. Journal of the Indian Society of Pedodontics and Preventive Dentistry, 2001, Volume: 19, Issue:4 Topics: Anti-Infective Agents, Local; Chelating Agents; Edetic Acid; Microbial Sensitivity Tests; Root Canal Irrigants; Smear Layer; Staphylococcus aureus; Streptococcus; Succimer	2001
Analysis of meso-2,3-dimercaptosuccinic acid in human urine by capillary electrophoresis using direct injection. Analytical and bioanalytical chemistry, 2003, Volume: 377, Issue:4 Topics: Chelating Agents; Dithiothreitol; Edetic Acid; Electrophoresis, Capillary; Humans; Stereoisomerism; Succimer; Time Factors; Urine	2003
Arsenic uptake by native fern species in Thailand: effect of chelating agents on hyperaccumulation of arsenic by Pityrogramma calomelanos. Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering, 2003, Volume: 38, Issue:12 Topics: Arsenic; Chelating Agents; Edetic Acid; Ferns; Plant Leaves; Soil Pollutants; Succimer; Thailand; Tissue Distribution	2003
Lead-induced oxidative stress and hematological alterations and their response to combined administration of calcium disodium EDTA with a thiol chelator in rats. Journal of biochemical and molecular toxicology, 2004, Volume: 18, Issue:4 Topics: Animals; Brain; Chelating Agents; Drug Therapy, Combination; Edetic Acid; Glutathione; Hemoglobins; Kidney; Lead; Lead Poisoning; Male; Metals; Oxidative Stress; Porphobilinogen Synthase; Protoporphyrins; Rats; Rats, Wistar; Succimer; Unithiol	2004
The need for vigilance: the persistence of lead poisoning in children. Pediatrics, 2005, Volume: 115, Issue:6 Topics: Cheek; Chelation Therapy; Child, Preschool; Dimercaprol; Drug Therapy, Combination; Edema; Edetic Acid; Environmental Exposure; Foreign Bodies; Humans; Lead; Lead Poisoning; Male; Pica; Play and Playthings; Protoporphyrins; Seizures; Self-Injurious Behavior; Succimer; Wounds, Gunshot	2005
Deaths resulting from hypocalcemia after administration of edetate disodium: 2003-2005. Pediatrics, 2006, Volume: 118, Issue:2 Topics: Autistic Disorder; Calcium; Chelating Agents; Chelation Therapy; Child, Preschool; Death, Sudden, Cardiac; Drug Therapy, Combination; Edetic Acid; Fatal Outcome; Female; Humans; Hypocalcemia; Hypoxia-Ischemia, Brain; Infusions, Intravenous; Lead Poisoning; Male; Medication Errors; Middle Aged; Naturopathy; Risk Management; Sodium; Succimer	2006
Reversal of lead-induced neuronal apoptosis by chelation treatment in rats: role of reactive oxygen species and intracellular Ca(2+). The Journal of pharmacology and experimental therapeutics, 2007, Volume: 322, Issue:1 Topics: Animals; Apoptosis; Behavior, Animal; Brain; Calcium; Chelating Agents; Edetic Acid; Lead; Male; Mitochondria; Neurons; Neurotransmitter Agents; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Succimer	2007
Infantile lead poisoning from an Asian tongue powder: a case report & subsequent public health inquiry. Clinical toxicology (Philadelphia, Pa.), 2008, Volume: 46, Issue:9 Topics: Chelating Agents; Drug Contamination; Edetic Acid; Fluorescence; Humans; Infant; Lead; Lead Poisoning; Male; Medicine, East Asian Traditional; Plant Preparations; Spectrometry, X-Ray Emission; Succimer; Thailand; Tongue	2008
Effects of chelators on mercury, iron, and lead neurotoxicity in cortical culture. Neurotoxicology, 2009, Volume: 30, Issue:1 Topics: Animals; Brain Chemistry; Cell Death; Cells, Cultured; Cerebral Cortex; Chelating Agents; Drug Synergism; Edetic Acid; Female; Iron; Lead; Mercuric Chloride; Methylmercury Compounds; Mice; Penicillamine; Pregnancy; Succimer; Thimerosal; Unithiol	2009
Fatal mercury poisoning and chelating agents. Forensic science international, 2010, Oct-10, Volume: 202, Issue:1-3 Topics: Chelating Agents; Dimercaprol; Edetic Acid; Humans; Male; Mercury Poisoning; Succimer; Suicide; Unithiol	2010
EDTA redistribution of lead and cadmium into the soft tissues in a human with a high lead burden - should DMSA always be used to follow EDTA in such cases? Alternative medicine review : a journal of clinical therapeutic, 2011, Volume: 16, Issue:2 Topics: Cadmium; Chelation Therapy; Dose-Response Relationship, Drug; Drug Therapy, Combination; Edetic Acid; Humans; Lead; Lead Poisoning; Male; Middle Aged; Occupational Exposure; Succimer; Tissue Distribution; Treatment Outcome	2011
[Outbreak of lead poisoning associated with Ayurvedic medicine]. Medicina clinica, 2015, Feb-20, Volume: 144, Issue:4 Topics: Abdominal Pain; Anemia, Hypochromic; beta-Thalassemia; Bursitis; Chelation Therapy; Edetic Acid; Female; Fibromyalgia; Humans; Lead Poisoning, Nervous System, Adult; Medicine, Ayurvedic; Middle Aged; Succimer	2015
Rare etiology of abdominal pain in an adolescent female. Clinical pediatrics, 2015, Volume: 54, Issue:1 Topics: Abdominal Pain; Adolescent; Chelating Agents; Diagnosis, Differential; Dimercaprol; Edetic Acid; Female; Hematemesis; Humans; Lead Poisoning; Succimer	2015
What is your diagnosis? Comminuted compression fracture of the last (free) thoracic vertebra. Journal of the American Veterinary Medical Association, 2015, Mar-15, Volume: 246, Issue:6 Topics: Animals; Bird Diseases; Chelating Agents; Eagles; Edetic Acid; Fatal Outcome; Female; Fractures, Comminuted; Mercury Poisoning; Radiography; Sarcocystis; Sarcocystosis; Seizures; Succimer; Thoracic Vertebrae	2015
Reversing the adverse biochemical effects in lead-intoxicated rats by N,N`- bis[(1,2-didehydro-1-hydroxy-2-thioxopyrid-4-yl)-carbonyl]- L-lysine. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 2018, Volume: 50 Topics: Animals; Chelating Agents; Chelation Therapy; Edetic Acid; Lead; Lead Poisoning; Male; Porphobilinogen Synthase; Protoporphyrins; Rats; Rats, Wistar; Succimer	2018
Clinical Chemistry of Abdominal X-Rays. Clinical chemistry, 2020, 06-01, Volume: 66, Issue:6 Topics: Edetic Acid; Humans; Infant; Lead; Lead Poisoning; Male; Paint; Radiography, Abdominal; Succimer	2020