Page last updated: 2024-08-17

edetic acid and propofol

edetic acid has been researched along with propofol in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (18.18)18.2507
2000's25 (75.76)29.6817
2010's2 (6.06)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Andresen, C; Gambus, PL; Goodale, DB; Minto, CF; Schnider, TW; Shafer, SL; Youngs, EJ1
Armijo, JA; Cuadrado, A; González, S; Sánchez, B; Solares, G1
Craig, DB1
Peterson, LR; Vidovich, MI; Wong, HY1
Anwar, M; Banister, R; Banister, RE; Feng, C; Feng, CJ; Kadowitz, P; Kadowitz, PJ; Kaye, A; Kaye, AD; Nossaman, B; Nossaman, BD; Turner, K1
Doyle, TJ; Gravenstein, N; Gulig, PA; Langevin, PB; Langevin, SO; Roberts, SA; Skinner, S1
Hart, B1
Haus, M1
Teres, D; Zaloga, GP1
Goodale, DB; Thompson, KA1
Teres, D; Youngs, E; Zaloga, GP1
Dedhia, HV; Fulda, G; Gelmont, D; Higgins, TL; Kett, DH; Ko, H; Kramer, KM; Levy, H; Murray, M; Teres, D; Thompson, KA; Zaloga, GP1
Abraham, E; Hall, JB; Papadakos, PJ; Tharratt, RS; Williams, GJ1
Bandi, V; Barr, J; Haupt, MT; Murray, MJ; Teres, D; Weinmann, M; Zaloga, GP1
Gilbert, HC; Horrow, JC; Maddi, R; Spiess, B; Vender, J; Wahr, J1
Cason, B; Fulda, GJ; Hall, JB; Herr, DL; Hickey, R; Kelly, K; Nejman, AM; Teres, D; Ulatowski, J; Zaloga, GP1
Cohen, IT; Goodale, DB; Hannallah, RS1
Baker, MT; Dehring, DJ; Gregerson, MS1
Janicki, PK; LaFleur, BJ; Rieschke, P1
Baker, MT; Buettner, GR; Gregerson, MS; Martin, SM1
Marik, P; Zaloga, GP1
Ganzberg, S; Harvey, BR1
Hashimoto, M; Inaba, S; Kouchi, A; Motomura, Y; Takahashi, M1
Cohen, IT; Finkel, JC; Goodale, DB; Hannallah, RS1
Marik, PE1
Baker, MT; Naguib, M1
Fukada, T; Jansson, JR; Kimura, S; Ozaki, M1
Fukada, T; Ozaki, M1
Cork, R; Rao, A; Wang, H1
Hara, H; Hasegawa, T; Iwama, T; Kotani, Y; Nagase, H; Nakajima, Y; Satoh, M; Shimazawa, M; Yoshimura, S1
Haitsma, JJ; Lachmann, B; Papadakos, PJ1
Bushuven, S; Heise, D1

Reviews

7 review(s) available for edetic acid and propofol

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Sulfite-induced propofol oxidation: a cause for radical concern.
    Critical care medicine, 2003, Volume: 31, Issue:3

    Topics: Chemistry, Pharmaceutical; Drug Contamination; Drug Stability; Edetic Acid; Free Radicals; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Lipid Peroxidation; Propofol; Safety; Sulfites

2003
Propofol: an immunomodulating agent.
    Pharmacotherapy, 2005, Volume: 25, Issue:5 Pt 2

    Topics: Anesthetics, Intravenous; Antioxidants; Chelating Agents; Chemistry, Pharmaceutical; Edetic Acid; Emulsions; Humans; Hypnotics and Sedatives; Immunologic Factors; Lipid Peroxidation; Propofol

2005
Propofol: the challenges of formulation.
    Anesthesiology, 2005, Volume: 103, Issue:4

    Topics: Chemistry, Pharmaceutical; Cyclodextrins; Drug Stability; Edetic Acid; Emulsions; Glycerol; Micelles; Particle Size; Prodrugs; Propofol; Sulfites

2005
Propofol EDTA and reduced incidence of infection.
    Anaesthesia and intensive care, 2006, Volume: 34, Issue:3

    Topics: Anesthetics, Intravenous; Anti-Infective Agents; Bacteria; Cross Infection; Drug Contamination; Edetic Acid; Humans; Incidence; Propofol; United States

2006
Development of a new generation of propofol.
    Current opinion in anaesthesiology, 2007, Volume: 20, Issue:4

    Topics: Chemistry, Pharmaceutical; Drug Stability; Edetic Acid; Emulsions; Glycerol; Nanotechnology; Particle Size; Prodrugs; Propofol

2007
[Propofol up2date. Part 1: history and pharmacological characteristics].
    Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 2013, Volume: 48, Issue:6

    Topics: Anesthetics, Intravenous; Antiemetics; Capital Punishment; Conscious Sedation; Contraindications; Drug Contamination; Edetic Acid; Emulsions; Excipients; Germany; Hemodynamics; History, 20th Century; Humans; Immunologic Factors; Propofol

2013

Trials

10 trial(s) available for edetic acid and propofol

ArticleYear
The influence of method of administration and covariates on the pharmacokinetics of propofol in adult volunteers.
    Anesthesiology, 1998, Volume: 88, Issue:5

    Topics: Adult; Aged; Aging; Anesthetics, Intravenous; Antidotes; Cross-Over Studies; Double-Blind Method; Drug Interactions; Edetic Acid; Female; Humans; Infusions, Intravenous; Injections, Intravenous; Male; Middle Aged; Propofol

1998
Propofol-containing sedatives increase levels of parathyroid hormone.
    Intensive care medicine, 2000, Volume: 26 Suppl 4

    Topics: Adult; Aged; Anesthetics, Intravenous; Calcium; Chelating Agents; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Edetic Acid; Female; Humans; Magnesium; Male; Middle Aged; Parathyroid Hormone; Preservatives, Pharmaceutical; Propofol

2000
Trace element homeostasis during continuous sedation with propofol containing EDTA versus other sedatives in critically ill patients.
    Intensive care medicine, 2000, Volume: 26 Suppl 4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthetics, Intravenous; APACHE; Calcium; Chelating Agents; Chi-Square Distribution; Critical Illness; Edetic Acid; Female; Hemodynamics; Humans; Male; Middle Aged; Odds Ratio; Preservatives, Pharmaceutical; Propofol; Prospective Studies; Statistics, Nonparametric; Trace Elements

2000
Effects of propofol containing EDTA on mineral metabolism in medical ICU patients with pulmonary dysfunction.
    Intensive care medicine, 2000, Volume: 26 Suppl 4

    Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Anesthetics, Intravenous; Calcium; Chelating Agents; Consumer Product Safety; Double-Blind Method; Edetic Acid; Female; Humans; Lung Diseases; Magnesium; Male; Middle Aged; Minerals; Odds Ratio; Preservatives, Pharmaceutical; Propofol; Respiration, Artificial; Respiratory Distress Syndrome; Treatment Outcome

2000
Cation metabolism during propofol sedation with and without EDTA in patients with impaired renal function.
    Intensive care medicine, 2000, Volume: 26 Suppl 4

    Topics: Adolescent; Adult; Anesthetics, Intravenous; Calcium; Cations; Chelating Agents; Double-Blind Method; Edetic Acid; Female; Humans; Intensive Care Units; Kidney; Logistic Models; Magnesium; Male; Middle Aged; Parathyroid Hormone; Preservatives, Pharmaceutical; Propofol; Renal Insufficiency; Respiration, Artificial; Statistics, Nonparametric

2000
Effect of propofol with and without EDTA on haemodynamics and calcium and magnesium homeostasis during and after cardiac surgery.
    Intensive care medicine, 2000, Volume: 26 Suppl 4

    Topics: Adult; Aged; Analysis of Variance; Anesthetics, Intravenous; Calcium; Cardiac Surgical Procedures; Chelating Agents; Double-Blind Method; Edetic Acid; Female; Hemodynamics; Homeostasis; Humans; Magnesium; Male; Middle Aged; Preservatives, Pharmaceutical; Propofol; Statistics, Nonparametric

2000
Safety and efficacy of propofol with EDTA when used for sedation of surgical intensive care unit patients.
    Intensive care medicine, 2000, Volume: 26 Suppl 4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analysis of Variance; Anesthetics, Intravenous; Calcium; Chelating Agents; Consumer Product Safety; Edetic Acid; Female; Hemodynamics; Homeostasis; Humans; Intensive Care Units; Magnesium; Male; Middle Aged; Postoperative Care; Preservatives, Pharmaceutical; Propofol; Prospective Studies; Statistics, Nonparametric

2000
The clinical and biochemical effects of propofol infusion with and without EDTA for maintenance anesthesia in healthy children undergoing ambulatory surgery.
    Anesthesia and analgesia, 2001, Volume: 93, Issue:1

    Topics: Adolescent; Ambulatory Surgical Procedures; Anesthesia Recovery Period; Anesthesia, Intravenous; Anesthetics, Intravenous; Calcium; Chelating Agents; Child; Child, Preschool; Double-Blind Method; Edetic Acid; Female; Hemodynamics; Homeostasis; Humans; Infant; Infusions, Intravenous; Kidney Function Tests; Male; Monitoring, Intraoperative; Propofol; Water-Electrolyte Balance

2001
Effects of EDTA- and sulfite-containing formulations of propofol on respiratory system resistance after tracheal intubation in smokers.
    Anesthesiology, 2003, Volume: 98, Issue:2

    Topics: Adult; Airway Resistance; Algorithms; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Chelating Agents; Double-Blind Method; Edetic Acid; Female; Humans; Intubation, Intratracheal; Male; Middle Aged; Monitoring, Intraoperative; Propofol; Respiratory Function Tests; Smoking; Sulfites

2003
Clinical and biochemical effects of propofol EDTA vs sevoflurane in healthy infants and young children.
    Paediatric anaesthesia, 2004, Volume: 14, Issue:2

    Topics: Ambulatory Surgical Procedures; Analysis of Variance; Anesthesia Recovery Period; Anesthetics, Inhalation; Anesthetics, Intravenous; Blood Pressure; Calcium; Chelating Agents; Child, Preschool; Edetic Acid; Heart Rate; Humans; Infant; Magnesium; Methyl Ethers; Nitrous Oxide; Oxygen; Propofol; Reference Values; Sevoflurane; Time Factors

2004

Other Studies

16 other study(ies) available for edetic acid and propofol

ArticleYear
Propofol concentrations in whole blood: influence of anticoagulants and storage time.
    Methods and findings in experimental and clinical pharmacology, 1998, Volume: 20, Issue:4

    Topics: Anticoagulants; Blood Preservation; Edetic Acid; Heparin; Humans; Oxalates; Propofol; Time Factors

1998
"Preservatives" in propofol.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1998, Volume: 45, Issue:9

    Topics: Anesthetics, Intravenous; Bacteria; Canada; Chelating Agents; Chemistry, Pharmaceutical; Drug Contamination; Edetic Acid; Humans; Preservatives, Pharmaceutical; Propofol; United States; United States Food and Drug Administration

1998
The effect of lidocaine on bacterial growth in propofol.
    Anesthesia and analgesia, 1999, Volume: 88, Issue:4

    Topics: Bacteria; Candida albicans; Edetic Acid; Lidocaine; Microbial Sensitivity Tests; Propofol; Pseudomonas aeruginosa; Serratia marcescens; Solutions; Staphylococcus aureus; Time Factors

1999
Responses to propofol in the pulmonary vascular bed of the rat.
    Acta anaesthesiologica Scandinavica, 1999, Volume: 43, Issue:4

    Topics: Acetylcholine; Adamantane; Adenosine Triphosphate; Adrenergic beta-Agonists; Anesthetics, Intravenous; Animals; Arachidonic Acid; Arginine; Blood Pressure; Chelating Agents; Cyclooxygenase Inhibitors; Dimethyl Sulfoxide; Diuretics; Dose-Response Relationship, Drug; Edetic Acid; Enzyme Inhibitors; Isoproterenol; Lung; Male; Meclofenamic Acid; Morpholines; Nitric Oxide Synthase; Nitroglycerin; Potassium Channel Blockers; Propofol; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; Solvents; Vasodilator Agents

1999
Growth of Staphylococcus aureus in Diprivan and Intralipid: implications on the pathogenesis of infections.
    Anesthesiology, 1999, Volume: 91, Issue:5

    Topics: Anesthetics, Intravenous; Animals; Edetic Acid; Fat Emulsions, Intravenous; Kinetics; Propofol; Rabbits; Staphylococcal Infections; Staphylococcus aureus; Temperature

1999
'Diprivan': a change of formulation.
    European journal of anaesthesiology, 2000, Volume: 17, Issue:1

    Topics: Anesthetics, Intravenous; Bacterial Infections; Chelating Agents; Chemistry, Pharmaceutical; Drug Contamination; Edetic Acid; Humans; Hypnotics and Sedatives; Postoperative Complications; Preservatives, Pharmaceutical; Propofol; Safety; United States; United States Food and Drug Administration

2000
Serious consequences to misuse of propofol anaesthetic.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 2000, Volume: 90, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Anesthetics, Intravenous; Drug Contamination; Edetic Acid; Humans; Propofol; South Africa

2000
The safety and efficacy of propofol containing EDTA: a randomised clinical trial programme focusing on cation and trace metal homeostasis in critically ill patients.
    Intensive care medicine, 2000, Volume: 26 Suppl 4

    Topics: Anesthetics, Intravenous; Cations; Chelating Agents; Consumer Product Safety; Critical Illness; Edetic Acid; Homeostasis; Humans; Preservatives, Pharmaceutical; Propofol; Trace Elements

2000
The recent development of propofol (DIPRIVAN).
    Intensive care medicine, 2000, Volume: 26 Suppl 4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthetics, Intravenous; Chelating Agents; Child; Child, Preschool; Consumer Product Safety; Drug Approval; Drug Contamination; Edetic Acid; Humans; Infections; Intensive Care Units; Middle Aged; Postoperative Complications; Preservatives, Pharmaceutical; Propofol; United States

2000
Sulfite supported lipid peroxidation in propofol emulsions.
    Anesthesiology, 2002, Volume: 97, Issue:5

    Topics: Ascorbic Acid; Edetic Acid; Emulsions; Fat Emulsions, Intravenous; Hydrogen-Ion Concentration; Lipid Peroxidation; Propofol; Soybean Oil; Sulfites

2002
Free radical and drug oxidation products in an intensive care unit sedative: propofol with sulfite.
    Critical care medicine, 2003, Volume: 31, Issue:3

    Topics: Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Critical Care; Dimerization; Drug Contamination; Drug Evaluation, Preclinical; Drug Stability; Edetic Acid; Electron Spin Resonance Spectroscopy; Emulsions; Free Radicals; Humans; Hypnotics and Sedatives; Oxidation-Reduction; Propofol; Quinones; Sulfites; Time Factors

2003
Growth of microorganisms in propofol and methohexital mixtures.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2003, Volume: 61, Issue:7

    Topics: Analysis of Variance; Anesthetics, Intravenous; Candida albicans; Chelating Agents; Colony Count, Microbial; Drug Contamination; Drugs, Generic; Edetic Acid; Escherichia coli; Humans; Methohexital; Preservatives, Pharmaceutical; Propofol; Pseudomonas aeruginosa; Staphylococcus aureus; Sulfites; Time Factors

2003
[Anesthetic management of a patient with suspected pseudothrombocytopenia].
    Masui. The Japanese journal of anesthesiology, 2003, Volume: 52, Issue:10

    Topics: Aged; Anesthesia, Epidural; Anesthesia, General; Anticoagulants; Edetic Acid; Heparin; Humans; Male; Methyl Ethers; Propofol; Sevoflurane; Sigmoid Neoplasms; Thrombocytopenia

2003
Microbial growth in propofol formulations with disodium edetate and the influence of venous access system dead space.
    Anaesthesia, 2007, Volume: 62, Issue:6

    Topics: Anesthetics, Intravenous; Bacteria; Chemistry, Pharmaceutical; Cross Infection; Drug Contamination; Drug Delivery Systems; Edetic Acid; Equipment Contamination; Equipment Design; Humans; Propofol

2007
Propofol exerts greater neuroprotection with disodium edetate than without it.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2008, Volume: 28, Issue:2

    Topics: Anesthetics, Intravenous; Animals; Apoptosis; Benzimidazoles; Brain Ischemia; Cell Count; Cell Survival; Chelating Agents; Drug Synergism; Edetic Acid; Fluorescent Dyes; Glucose; Hypoxia; In Situ Nick-End Labeling; Infarction, Middle Cerebral Artery; Male; Mice; Neuroprotective Agents; Neurotoxicity Syndromes; PC12 Cells; Propofol; Rats; Zinc

2008
Additives in intravenous anesthesia modulate pulmonary inflammation in a model of LPS-induced respiratory distress.
    Acta anaesthesiologica Scandinavica, 2009, Volume: 53, Issue:2

    Topics: Acute Lung Injury; Adjuvants, Anesthesia; Anesthesia, Intravenous; Animals; Bronchoalveolar Lavage Fluid; Chemokine CXCL2; Edetic Acid; Interleukin-6; Ketamine; Lipopolysaccharides; Midazolam; Propofol; Pulmonary Gas Exchange; Random Allocation; Rats; Rats, Sprague-Dawley; Respiration, Artificial; Respiratory Distress Syndrome; Sulfites; Systemic Inflammatory Response Syndrome; Tumor Necrosis Factor-alpha

2009