edetic acid has been researched along with indomethacin in 63 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 22 (34.92) | 18.7374 |
| 1990's | 28 (44.44) | 18.2507 |
| 2000's | 9 (14.29) | 29.6817 |
| 2010's | 3 (4.76) | 24.3611 |
| 2020's | 1 (1.59) | 2.80 |
| Authors | Studies |
|---|---|
| Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Patscheke, H | 1 |
| Burke, G; Friedman, Y; Lang, M | 1 |
| Adkinson, NF | 1 |
| Ishikawa, Y; Newcombe, DS | 1 |
| Clothier, JL; Eastham, CL; Lamping, KG; Marcus, ML | 1 |
| Herrera, J; Manzanares, J; Marín, C; Rodríguez-Iturbe, B | 1 |
| Davies, GR; Marsh, FP; Rampton, DS; Wilkie, ME | 1 |
| Bjarnason, I; Fehilly, B; Levi, AJ; Menzies, IS; Smethurst, P | 2 |
| Bjarnason, I; Macpherson, A; McElnay, JC; Menzies, IS; Passmore, AP; Smethurst, P; Walker, F | 1 |
| Davies, GR; Rampton, DS | 1 |
| Clark, DA; Gu, XA; Miller, MJ; Zhang, XJ | 1 |
| Banerjee, AK; Peters, TJ | 1 |
| Fitzgerald, DJ; FitzGerald, GA; Murray, R; Takahara, K | 1 |
| Hechtman, HB; Morel, NM; Petruzzo, PP; Shepro, D | 1 |
| Bjarnason, I; Fenn, CG; Lee, CE; Levi, AJ; Menzies, IS; Smethurst, P | 1 |
| Giuliani, S; Maggi, CA; Meli, A; Patacchini, R | 1 |
| Harper, MJ; Jones, MA; Norris, CJ; Woodard, DS | 1 |
| Bjarnason, I; Clark, P; Levi, J; Menzies, I; Peters, T; Smethurst, P | 1 |
| Schneider, W; Wehmeier, A | 1 |
| Aruoma, OI; Halliwell, B | 1 |
| Dierichs, R; Patscheke, H | 1 |
| Kanai, K; Kondo, E | 1 |
| Ohshima, Y; Usui, Y; Yoshida, K | 1 |
| Conte, B; Giuliani, S; Maggi, CA; Manzini, S; Meli, A; Parlani, M | 1 |
| Carlini, CR; Guimarães, JA; Ribeiro, JM | 1 |
| Ziboh, VA | 1 |
| Görög, P; Kovács, IB | 1 |
| Emmrich, R | 1 |
| Nitta, T; Suzuki, T | 1 |
| Burka, JF; Saad, MH | 1 |
| Lebret, M; Rendu, F | 1 |
| Morris, HG; Shepperdson, FT; Sherman, NA | 1 |
| Andersson, H; Nylander, O; Sababi, M; Wilander, E | 1 |
| Barboza, M; Chaves, F; Gutiérrez, JM | 1 |
| Goto, Y; Horie, K; Isayama, T; Naono, T; Nobunaga, M; Shingu, M; Tomari, K; Yasutake, C | 1 |
| Li, ZY; Lian, EC; Yu, TF | 1 |
| Colony, PC; Gerstle, JT; Kauffman, GL; Seaton, J | 1 |
| Antoon, JS; Chmaisse, HM; Grisham, MB; Kvietys, PR; Perry, MA | 1 |
| Chayvialle, JA; Cuber, JC; Minaire, Y; Mion, F | 1 |
| Curtis, GH; Gall, DG; MacNaughton, WK | 1 |
| Davies, GR; Rampton, DS; Wilkie, ME | 1 |
| Choi, VM; Chooi, J; Coates, JE; Russell, AS; Thomson, AB | 1 |
| Berman, SK; Blank, MA; Ems, BL; Gibson, GW; Myers, WR; Phipps, RJ; Smith, PN | 1 |
| Davies, NM; Jamali, F | 1 |
| Davies, NM; Jamali, F; Wright, MR | 1 |
| Flemström, G; Hällgren, A; Hellgren, S; Hellström, PM; Lördal, M; Nylander, O | 1 |
| Antoon, JS; Perry, MA | 1 |
| Flemström, G; Hällgren, A; Nylander, O | 1 |
| Alican, I; Bozkurt, A; Gürbüz, V; Haklar, G; Kurtel, H; Oktar, B; Yegen, C; Yüksel, M | 1 |
| Flemström, G; Hellgren, S; Nylander, O | 1 |
| Duckles, SP; Geary, GG; Krause, DN | 1 |
| Bjarnason, I; Bolognese, J; Crane, R; Hoover, M; Quan, H; Sigthorsson, G; Simon, T | 1 |
| Huang, TF; Wang, WJ | 1 |
| Gevensleben, R; Grube, A; Grünefeld, J; Zinner, G | 1 |
| Dasgupta, SC; Gomes, A; Karmakar, S; Muhuri, DC; Nagchaudhuri, AK | 1 |
| Bon, C; Cruz-Höfling, MA; Ferreira de Araújo, PM; Guimarães, AQ; Lôbo de Araújo, A | 1 |
| Dasgupta, SC; Gomes, A; Muhuri, D | 1 |
| Jansook, P; Loftsson, T | 1 |
| Aihara, E; Hentz, CL; Korman, AM; Montrose, MH; Perry, NPJ; Prasad, V; Shull, GE | 1 |
| Cangiano, LR; DeVries, TJ; Ipharraguerre, IR; McNeil, B; Renaud, J; Steele, MA; Villot, C | 1 |
1 review(s) available for edetic acid and indomethacin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
7 trial(s) available for edetic acid and indomethacin
| Article | Year |
|---|---|
Effect of prostaglandin synthesis inhibition on glomerular filtration rate in renal transplant recipients.
Topics: Adolescent; Adult; Chromium Radioisotopes; Double-Blind Method; Edetic Acid; Female; Glomerular Filtration Rate; Humans; Indomethacin; Kidney Transplantation; Male; Middle Aged; Prostaglandins; Prostaglandins E | 1992 |
Effects of indomethacin and misoprostol on renal function in healthy volunteers.
Topics: Adult; Chromium Radioisotopes; Creatinine; Drug Therapy, Combination; Edetic Acid; Glomerular Filtration Rate; Humans; Indomethacin; Kidney; Male; Misoprostol | 1992 |
Misoprostol reduces indomethacin-induced changes in human small intestinal permeability.
Topics: 3-O-Methylglucose; Adult; Alprostadil; Edetic Acid; Humans; Indomethacin; Intestine, Small; Male; Methylglucosides; Misoprostol; Permeability; Rhamnose; Xylose | 1989 |
Effect of prostaglandin on indomethacin-induced increased intestinal permeability in man.
Topics: 3-O-Methylglucose; Adult; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Chromium Radioisotopes; Edetic Acid; Humans; Indomethacin; Intestinal Absorption; Male; Methylglucosides; Prostaglandins E; Prostaglandins, Synthetic; Rhamnose; Rioprostil; Xylose | 1989 |
Effects of metronidazole and misoprostol on indomethacin-induced changes in intestinal permeability.
Topics: Adult; Chromium Radioisotopes; Double-Blind Method; Edetic Acid; Female; Humans; Indomethacin; Intestinal Absorption; Male; Mannitol; Metronidazole; Middle Aged; Misoprostol; Permeability | 1993 |
COX-2 inhibition with rofecoxib does not increase intestinal permeability in healthy subjects: a double blind crossover study comparing rofecoxib with placebo and indomethacin.
Topics: Adolescent; Adult; Chromium Radioisotopes; Cross-Over Studies; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Double-Blind Method; Edetic Acid; Female; Humans; Indomethacin; Intestinal Mucosa; Isoenzymes; Lactones; Male; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Sulfones | 2000 |
Induction of leaky gut by repeated intramuscular injections of indomethacin to preweaning Holstein calves.
Topics: Animal Feed; Animals; Body Weight; Cattle; Chromium; Diet; Edetic Acid; Indomethacin; Injections, Intramuscular; Lactulose; Male; Milk; Weaning | 2022 |
55 other study(ies) available for edetic acid and indomethacin
| Article | Year |
|---|---|
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics | 2011 |
Correlation of activation and aggregation of platelets. Discrimination between anti-activating and anti-aggregating agents.
Topics: Adenosine Diphosphate; Blood Platelets; Calcium; Edetic Acid; Humans; In Vitro Techniques; Indomethacin; Platelet Aggregation; Prostaglandin Endoperoxides; Sialic Acids; Temperature; Thromboxanes | 1979 |
Further characterization of bovine thyroid prostaglandin synthase.
Topics: 5,8,11,14-Eicosatetraynoic Acid; 8,11,14-Eicosatrienoic Acid; Animals; Bucladesine; Cattle; Cyclic AMP; Edetic Acid; Fatty Acids, Unsaturated; In Vitro Techniques; Indomethacin; Kinetics; Mixed Function Oxygenases; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; Subcellular Fractions; Theophylline; Thyroid Gland; Thyrotropin | 1975 |
Prostaglandin production by human peripheral blood cells in vitro.
Topics: Anti-Inflammatory Agents; Blood Platelets; Calcimycin; Cell Separation; Edetic Acid; Humans; In Vitro Techniques; Indomethacin; Kinetics; Leukocytes; Prostaglandins E; Prostaglandins F; Temperature; Zymosan | 1977 |
The effect of anti-inflammatory agents on human synovial fibroblast prostaglandin synthetase.
Topics: Anti-Inflammatory Agents; Aspirin; Catecholamines; Cells, Cultured; Edetic Acid; Fibroblasts; Gold; Humans; Hydrocortisone; Indicators and Reagents; Indomethacin; Methods; Mixed Function Oxygenases; Penicillamine; Phenylbutazone; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; Prostaglandins F; Sulfhydryl Compounds; Synovial Membrane | 1976 |
Coronary microvascular response to endothelin is dependent on vessel diameter and route of administration.
Topics: Administration, Topical; Animals; Arteries; Arterioles; Coronary Circulation; Cyclooxygenase Inhibitors; Dogs; Edetic Acid; Endothelins; Female; Hemodynamics; Indomethacin; Injections, Intra-Arterial; Male; Microcirculation; Vasoconstriction | 1992 |
Effects of nonsteroidal antiinflammatory drugs on permeability of the small intestine in humans.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Edetic Acid; Female; Humans; Indomethacin; Intestine, Small; Male; Nabumetone; Permeability; Rhamnose | 1992 |
Glucose and citrate reduce the permeability changes caused by indomethacin in humans.
Topics: Adult; Citrates; Citric Acid; Edetic Acid; Female; Glucose; Humans; Indomethacin; Intestine, Small; Male; Permeability; Rhamnose | 1992 |
The pro-drug sulindac may reduce the risk of intestinal damage associated with the use of conventional non-steroidal anti-inflammatory drugs.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Edetic Acid; Humans; Indomethacin; Intestinal Diseases; Intestinal Mucosa; Intestines; Mannitol; Middle Aged; Permeability; Prodrugs; Sulindac; Urea | 1991 |
Importance of local versus systemic effects of non-steroidal anti-inflammatory drugs in increasing small intestinal permeability in man.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Double-Blind Method; Edetic Acid; Female; Glucose; Humans; Indomethacin; Intestinal Absorption; Intestine, Small; Male; Nabumetone; Random Allocation; Rhamnose; Xylose | 1991 |
Acute intestinal injury induced by acetic acid and casein: prevention by intraluminal misoprostol.
Topics: Acetates; Alprostadil; Animals; Calcium Gluconate; Caseins; Cell Membrane Permeability; Chromium Radioisotopes; Drug Synergism; Edetic Acid; Fluorescein-5-isothiocyanate; Fluoresceins; Fluorescent Dyes; Histamine; Histamine Antagonists; Hydrogen-Ion Concentration; Indomethacin; Intestine, Small; Male; Misoprostol; Rabbits; Serum Albumin, Bovine; Thiocyanates | 1991 |
Experimental non-steroidal anti-inflammatory drug-induced enteropathy in the rat: similarities to inflammatory bowel disease and effect of thromboxane synthetase inhibitors.
Topics: Animals; Cell Membrane Permeability; Chromium Radioisotopes; Disease Models, Animal; Edetic Acid; Ileum; Imidazoles; Indomethacin; Inflammatory Bowel Diseases; Jejunum; Male; Peroxidase; Prednisolone; Rats; Rats, Inbred Strains; Sulfasalazine; Tetracycline; Thromboxane-A Synthase | 1990 |
The response to thromboxane A2 analogues in human platelets. Discrimination of two binding sites linked to distinct effector systems.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Biphenyl Compounds; Blood Platelets; Bridged Bicyclo Compounds, Heterocyclic; Edetic Acid; Fatty Acids, Unsaturated; Heptanoic Acids; Humans; Hydrazines; In Vitro Techniques; Indomethacin; Kinetics; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Receptors, Prostaglandin; Receptors, Thromboxane; Structure-Activity Relationship; Thrombin; Thromboxane A2; Thromboxanes | 1990 |
Inflammatory agonists that increase microvascular permeability in vivo stimulate cultured pulmonary microvessel endothelial cell contraction.
Topics: Angiotensin II; Animals; Bradykinin; Calcium; Capillary Permeability; Cattle; Cells, Cultured; Cyclic GMP; Edetic Acid; Endothelium, Vascular; Epoprostenol; Gallic Acid; Indomethacin; Intercellular Junctions; Isoproterenol; Myosin-Light-Chain Kinase; Prostaglandin Endoperoxides, Synthetic; Protein Kinase C; Pulmonary Edema; Second Messenger Systems; Tetradecanoylphorbol Acetate; Thrombin; Trifluoperazine | 1990 |
Potent contractile effect of endothelin in isolated guinea-pig airways.
Topics: Animals; Bronchi; Edetic Acid; Endothelins; Guinea Pigs; In Vitro Techniques; Indomethacin; Isoproterenol; Muscle Contraction; Muscle, Smooth; Nifedipine; Peptides; Tetrodotoxin; Trachea | 1989 |
Prostaglandin synthesis by day-6 rabbit blastocysts in vitro.
Topics: Animals; Arachidonic Acids; Atropine; Blastocyst; Calcium; Carbachol; Culture Techniques; Edetic Acid; Female; Indomethacin; Prostaglandins; Rabbits | 1989 |
Platelet volume parameters as a diagnostic tool: the influence of anticoagulation and storage conditions on platelet impedance volume.
Topics: Anticoagulants; Blood Platelets; Blood Preservation; Citrates; Citric Acid; Colforsin; Edetic Acid; Glutaral; Humans; Hydrogen-Ion Concentration; Indomethacin; Platelet Count; Temperature; Theophylline | 1989 |
Inactivation of alpha 1-antiproteinase by hydroxyl radicals. The effect of uric acid.
Topics: alpha 1-Antitrypsin; Ascorbic Acid; Blood Proteins; Chemical Phenomena; Chemistry; Edetic Acid; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydroxides; Hydroxyl Radical; Hypoxanthine; Hypoxanthines; Indomethacin; Iron; Nitrous Oxide; Pancreatic Elastase; Piroxicam; Protease Inhibitors; Pulse Radiolysis; Superoxides; Uric Acid; Xanthine Oxidase | 1989 |
Cationized ferritin as a platelet-stimulating surface probe. Binding to platelets and effects on platelet function.
Topics: Agglutination; Alprostadil; Binding Sites; Blood Platelets; Dose-Response Relationship, Drug; Edetic Acid; Ferritins; Humans; Indomethacin; Neuraminidase; Plasma; Platelet Activating Factor; Platelet Aggregation; Serotonin; Tritium | 1986 |
Bactericidal activity of the membrane fraction isolated from phagocytes of mice and its stimulation by melittin.
Topics: Animals; Bee Venoms; Cell Membrane; Edetic Acid; Escherichia coli; Indomethacin; Male; Melitten; Mice; Mycobacterium; Mycobacterium bovis; Mycobacterium tuberculosis; Neutrophils; Phagocytes; Phospholipases A; Phospholipases A2; Staphylococcus aureus | 1986 |
Platelet aggregation by group B streptococci.
Topics: Aspirin; Blood Platelets; Edetic Acid; Humans; Indomethacin; L-Lactate Dehydrogenase; Platelet Aggregation; Platelet Count; Quinacrine; Serotonin; Streptococcus agalactiae | 1987 |
The effect of nifedipine on spontaneous, drug-induced and reflexly-activated contractions of the rat urinary bladder: evidence for the participation of an intracellular calcium store to micturition contraction.
Topics: Adenosine Triphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Carbachol; Edetic Acid; Hemodynamics; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Rats; Rats, Inbred Strains; Reflex; Urinary Bladder; Urination | 1988 |
Platelet release reaction and aggregation induced by canatoxin, a convulsant protein: evidence for the involvement of the platelet lipoxygenase pathway.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Adenosine Monophosphate; Animals; Arachidonate Lipoxygenases; Blood Platelets; Caffeine; Creatine Kinase; Drug Interactions; Edetic Acid; Epoprostenol; Guinea Pigs; Humans; In Vitro Techniques; Indicators and Reagents; Indomethacin; Lectins; Lipoxygenase; Phosphocreatine; Plant Proteins; Platelet Aggregation; Quinacrine; Rabbits; Species Specificity; Synaptosomes; Thrombin; Toxins, Biological | 1985 |
Biosynthesis of prostaglandin E 2 in human skin: subcellular localization and inhibition by unsaturated fatty acids and anti-inflammatory drugs.
Topics: Arachidonic Acids; Aspirin; Carbon Isotopes; Chromatography, Gas; Chromatography, Thin Layer; Dexamethasone; Edetic Acid; Fatty Acids, Unsaturated; Humans; Indomethacin; Kinetics; Microsomes; Prostaglandins; Skin; Subcellular Fractions; Time Factors; Triamcinolone Acetonide | 1973 |
The effect of anti-inflammatory drugs on the aggregation and adhesiveness of platelets, red cells and leukocytes.
Topics: Adenosine Diphosphate; Aminosalicylic Acids; Animals; Anti-Inflammatory Agents; Antigen-Antibody Complex; Cell Adhesion; Chloroquine; Collagen; Dextrans; Edetic Acid; Endotoxins; Erythrocytes; Fibrinogen; Flufenamic Acid; Gelatin; Humans; In Vitro Techniques; Indomethacin; Leukocytes; Phenylbutazone; Phenylpropionates; Platelet Adhesiveness; Prednisolone; Rats; Thrombosis | 1972 |
[Hydroxyproline excretion in urine in chronic connective tissue disease].
Topics: Adrenocorticotropic Hormone; Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Collagen Diseases; Dermatomyositis; Edetic Acid; Female; Humans; Hydroxyproline; Indomethacin; Lupus Erythematosus, Systemic; Male; Middle Aged; Phenylbutazone; Polyarteritis Nodosa; Prednisone; Psoriasis; Scleroderma, Systemic; Spondylitis, Ankylosing | 1970 |
Fc gamma 2b receptor-mediated prostaglandin synthesis by a murine macrophage cell line (P388D1).
Topics: Acetophenones; Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Cell Line; Chromatography, Thin Layer; Cytochalasin D; Cytochalasins; Edetic Acid; Indomethacin; Macrophages; Mice; Phagocytosis; Prostaglandins; Receptors, Fc; Receptors, IgG; Receptors, Immunologic; Rosette Formation | 1982 |
Role of calcium in arachidonic acid-induced contractions of guinea pig airways.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Calcium Channel Blockers; Edetic Acid; Gallic Acid; Guinea Pigs; In Vitro Techniques; Indomethacin; Lanthanum; Lung; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Nitrendipine; SRS-A; Trachea; Verapamil | 1984 |
Interaction of wheat germ agglutinin with human platelets: a model for studying platelet response.
Topics: Alprostadil; Arginine; Blood Platelets; Chlorpromazine; Colchicine; Creatine Kinase; Cytochalasin B; Edetic Acid; Humans; In Vitro Techniques; Indomethacin; Lectins; Phosphocreatine; Platelet Aggregation; Prostaglandins E; Wheat Germ Agglutinins | 1984 |
Variables associated with radioimmunoassay of prostaglandins in plasma.
Topics: Aspirin; Edetic Acid; False Positive Reactions; Humans; Indomethacin; Prostaglandins; Radioimmunoassay; Specimen Handling; Thromboxane B2 | 1981 |
Prostaglandins reduce hydrochloric acid-induced increase in duodenal mucosal permeability by a mechanism not related to stimulation of alkaline secretion.
Topics: Animals; Bicarbonates; Chromium Radioisotopes; Dinoprostone; Duodenum; Edetic Acid; Hydrochloric Acid; Hydrogen-Ion Concentration; In Vitro Techniques; Indomethacin; Intestinal Mucosa; Male; Permeability; Prostaglandins; Rats; Rats, Sprague-Dawley | 1995 |
Pharmacological study of edema induced by venom of the snake Bothrops asper (terciopelo) in mice.
Topics: Animals; Bothrops; Crotalid Venoms; Dexamethasone; Edema; Edetic Acid; Indomethacin; Mice; Prazosin; Receptors, Adrenergic, alpha | 1995 |
Role of oxygen radicals and IL-6 in IL-1-dependent cartilage matrix degradation.
Topics: alpha 1-Antitrypsin; Arthritis, Rheumatoid; Cartilage; Cells, Cultured; Collagenases; Edetic Acid; Free Radical Scavengers; Glycoproteins; Humans; Indomethacin; Interleukin-1; Interleukin-6; Matrix Metalloproteinase Inhibitors; Superoxides; Tissue Inhibitor of Metalloproteinases | 1994 |
Purification and characterization of L-amino acid oxidase from king cobra (Ophiophagus hannah) venom and its effects on human platelet aggregation.
Topics: Alprostadil; Amino Acid Oxidoreductases; Animals; Antimycin A; Aspirin; Blood Coagulation Tests; Blood Platelets; Catalase; Chromatography, Gel; Chromatography, Ion Exchange; Drug Interactions; Edetic Acid; Elapid Venoms; Electrophoresis, Polyacrylamide Gel; Heparin; Hirudins; Humans; Hydrogen Peroxide; Indomethacin; Isoelectric Point; L-Amino Acid Oxidase; Molecular Weight; Nitroprusside; Platelet Aggregation; Quinacrine; Thromboxane A2; Verapamil | 1994 |
The association between PGE2 activity and mucosal permeability in proximal small bowel.
Topics: Aging; Animals; Cell Membrane Permeability; Chromium Radioisotopes; Dinoprostone; Edetic Acid; Indomethacin; Intestinal Mucosa; Intestine, Small; Prostaglandin-Endoperoxide Synthases; Radioimmunoassay; Rats; Rats, Sprague-Dawley | 1994 |
Role of leukocytes in indomethacin-induced small bowel injury in the rat.
Topics: Animals; Blood Pressure; Edetic Acid; Indomethacin; Injections, Intravenous; Intestinal Mucosa; Intestine, Small; Jejunum; Leukocytes; Male; Perfusion; Permeability; Rats; Rats, Wistar | 1994 |
Short term effects of indomethacin on rat small intestinal permeability. Role of eicosanoids and platelet activating factor.
Topics: 16,16-Dimethylprostaglandin E2; Animals; Culture Techniques; Edetic Acid; Eicosanoids; Ileum; Indomethacin; Kinetics; Leukotriene B4; Leukotriene D4; Male; Permeability; Platelet Activating Factor; Rats; Rats, Wistar | 1994 |
Effect of cyclooxygenase inhibition on macromolecular transport in rat gastric mucosa.
Topics: Animals; Biological Transport; Chromium Radioisotopes; Dinoprostone; Edetic Acid; Gastric Mucosa; In Vitro Techniques; Indomethacin; Iodine Radioisotopes; Permeability; Piroxicam; Rats; Rats, Inbred Strains; Serum Albumin, Bovine; Sodium Fluoride; Stomach | 1993 |
Small bowel permeability--a variable effect of NSAIDS.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Chromium Radioisotopes; Diclofenac; Edetic Acid; Female; Humans; Indomethacin; Intestinal Absorption; Intestine, Small; Male; Mannitol; Middle Aged; Permeability; Piroxicam | 1995 |
Nonclinical model for assessing gastric effects of bisphosphonates.
Topics: Alendronate; Animals; Chelating Agents; Diphosphonates; Edetic Acid; Egtazic Acid; Etidronic Acid; Indomethacin; Male; Pamidronate; Rats; Rats, Sprague-Dawley; Risedronic Acid; Stomach | 1997 |
Pharmacological protection of NSAID-induced intestinal permeability in the rat: effect of tempo and metronidazole as potential free radical scavengers.
Topics: Administration, Oral; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Cyclic N-Oxides; Edetic Acid; Flurbiprofen; Free Radical Scavengers; Indomethacin; Intestinal Absorption; Intestinal Mucosa; Isotope Labeling; Male; Metronidazole; Peritonitis; Permeability; Protein-Losing Enteropathies; Rats; Rats, Sprague-Dawley; Spin Labels; Stomach Ulcer | 1997 |
Toxicokinetics of indomethacin-induced intestinal permeability in the rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Edetic Acid; Indomethacin; Intestinal Mucosa; Intestines; Male; Permeability; Rats; Rats, Sprague-Dawley | 1997 |
Neurokinin A increases duodenal mucosal permeability, bicarbonate secretion, and fluid output in the rat.
Topics: Animals; Bicarbonates; Chromium Radioisotopes; Duodenum; Edetic Acid; Gastrointestinal Motility; Hexamethonium; Indomethacin; Infusions, Intravenous; Intestinal Mucosa; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Peptides, Cyclic; Permeability; Pressure; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-2; Time Factors | 1997 |
Role of neutrophils and mast cells in acute indomethacin-induced small bowel injury in the rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chromium Radioisotopes; Dexamethasone; Edetic Acid; Immunohistochemistry; Indomethacin; Intestinal Diseases; Intestine, Small; Leukocytes; Male; Mast Cells; Neutrophils; Rats; Rats, Wistar; Time Factors | 1997 |
Interaction between neurokinin A, VIP, prostanoids, and enteric nerves in regulation of duodenal function.
Topics: Analysis of Variance; Animals; Bicarbonates; Chromium Radioisotopes; Duodenum; Edetic Acid; Gastrointestinal Motility; Indomethacin; Infusions, Intravenous; Intestinal Absorption; Intestinal Mucosa; Lidocaine; Male; Metabolic Clearance Rate; Muscle, Smooth; Neurokinin A; Neurons; Pressure; Prostaglandins; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Vasoactive Intestinal Peptide | 1998 |
Role of nitric oxide in indomethacin-induced gastric mucosal dysfunction in the rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chelating Agents; Edetic Acid; Enzyme Inhibitors; Female; Gastric Mucosa; Indomethacin; Lipid Peroxides; Luminescent Measurements; Male; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Oxidation-Reduction; Peroxidase; Proteins; Rats; Rats, Wistar; Stomach Ulcer; Sulfhydryl Compounds | 1999 |
Nitric oxide prevents rat duodenal contractions induced by potentially noxious agents.
Topics: Animals; Arginine; Bicarbonates; Capsaicin; Carbon Dioxide; Chromium Radioisotopes; Crosses, Genetic; Duodenum; Edetic Acid; Ethanol; Gastrointestinal Motility; Hydrochloric Acid; Indomethacin; Intestinal Mucosa; Intubation, Gastrointestinal; Male; Metabolic Clearance Rate; Muscle Contraction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Perfusion; Rats; Rats, Inbred Lew; Rats, Inbred Strains | 2000 |
Gonadal hormones affect diameter of male rat cerebral arteries through endothelium-dependent mechanisms.
Topics: Animals; Apamin; Body Weight; Cerebral Arteries; Edetic Acid; Endothelium, Vascular; Estradiol; In Vitro Techniques; Indomethacin; Male; Muscle Tonus; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Orchiectomy; Rats; Rats, Inbred F344; Testosterone; Tetraethylammonium | 2000 |
A novel tetrameric venom protein, agglucetin from Agkistrodon acutus, acts as a glycoprotein Ib agonist.
Topics: Agkistrodon; Alprostadil; Amino Acid Sequence; Animals; Antibodies, Monoclonal; Binding, Competitive; Blood Platelets; Calcium Signaling; Chelating Agents; Crotalid Venoms; Dose-Response Relationship, Drug; Edetic Acid; Epitopes; Fibrinolytic Agents; Heparin; Hirudins; Humans; Indomethacin; Intercellular Signaling Peptides and Proteins; Molecular Sequence Data; Molecular Weight; Peptides; Platelet Aggregation; Platelet Glycoprotein GPIb-IX Complex; Prostaglandin Antagonists; Protein Conformation; Protein Subunits; Sequence Alignment; Sequence Homology, Amino Acid; Spectrometry, Mass, Electrospray Ionization; Thromboxane B2; von Willebrand Factor | 2001 |
[The hydroxam reaction of indometacin and acemetacin].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chelating Agents; Chromatography, High Pressure Liquid; Edetic Acid; Hydroxamic Acids; Indicators and Reagents; Indomethacin; Spectrophotometry, Ultraviolet | 2003 |
Isolation of a haemorrhagic protein toxin (SA-HT) from the Indian venomous butterfish (Scatophagus argus, Linn) sting extract.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Capillaries; Chromatography, Ion Exchange; Cyproheptadine; Dose-Response Relationship, Drug; Edema; Edetic Acid; Electrophoresis, Polyacrylamide Gel; Female; Fish Proteins; Fish Venoms; Gastrointestinal Agents; Guinea Pigs; Indomethacin; Lipoxygenase; Mice; Muscle, Smooth; Perciformes; Permeability; Rats; Spine; Superoxide Dismutase; Time Factors; Trypsin; Ultraviolet Rays; Uterus | 2004 |
Pharmacological and histopathological characterization of Bothrops lanceolatus (Fer de lance) venom-induced edema.
Topics: Adrenergic beta-Antagonists; Animals; Antiemetics; Arachidonic Acid; Bothrops; Bradykinin; Cardiovascular Agents; Crotalid Venoms; Dexamethasone; Dose-Response Relationship, Drug; Edema; Edetic Acid; Extremities; Histamine; Histamine H1 Antagonists; Indomethacin; Mast Cells; Methysergide; Pyrilamine; Rats; Rats, Wistar; Serotonin; Time Factors; Vasoconstrictor Agents | 2004 |
Lethal, oedema, haemorrhagic activity of spotted butterfish (Scatophagus argus, Linn) sting extract and its neutralization by antiserum and pharmacological antagonists.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Cyproheptadine; Edema; Edetic Acid; Fish Venoms; Hemagglutination; Hemorrhage; Immune Sera; Indomethacin; Inflammation; Male; Mice; Perciformes; Rabbits; Rats; Temperature; Time Factors; Ultraviolet Rays | 2005 |
CDs as solubilizers: effects of excipients and competing drugs.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Amphotericin B; Benzalkonium Compounds; beta-Cyclodextrins; Chemistry, Pharmaceutical; Dexamethasone; Edetic Acid; Excipients; gamma-Cyclodextrins; Hydrocortisone; Hypromellose Derivatives; Indomethacin; Methylcellulose; Solubility | 2009 |
In vivo epithelial wound repair requires mobilization of endogenous intracellular and extracellular calcium.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Boron Compounds; Calcium; Calcium Channel Blockers; Calcium Signaling; Calcium-Transporting ATPases; Chelating Agents; Edetic Acid; Egtazic Acid; Estrenes; Gastric Mucosa; Indomethacin; Mice; Mice, Knockout; Phosphodiesterase Inhibitors; Pyrrolidinones; Verapamil; Wound Healing | 2013 |