Page last updated: 2024-08-17

edetic acid and acetaminophen

edetic acid has been researched along with acetaminophen in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19905 (26.32)18.7374
1990's1 (5.26)18.2507
2000's3 (15.79)29.6817
2010's8 (42.11)24.3611
2020's2 (10.53)2.80

Authors

AuthorsStudies
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dascombe, MJ; Milton, AS1
Dybing, E1
Fogg, AG; Summan, AM1
Beales, D; Hue, DP; McLean, AE1
Büch, H; Hey, D; Rummel, W; Staudinger, H; Ullrich, V1
Bateman, DN; Rawlins, MD; Woodhouse, KW1
Batteux, F; Bedda, S; Calmus, Y; Chéreau, C; Conti, F; Goulvestre, C; Jaffray, P; Laurent, A; Soubrane, O; Tran, A; Tran-Van Nhieu, J; Weill, B1
de Carvalho, RM; Freire, RS; Kubota, LT; Rath, S1
Guiry, KP; Kelleher, JM; Lawrence, SE; McAuliffe, MT; Moynihan, HA; Ryan, AL1
Barfield, M; Dopson, WJ; Gade, SD; Lovatt, CA; Melich, D; Moose, TA; Overvold, CR; Parry, SP; Spooner, N; Stokes, AH1
Dear, J1
Ignarro, LJ; Jynge, P; Karlsson, JOG; Lundström, I1
Black, P; Dear, JW; Gallagher, B; Grahamslaw, J; Henriksen, D; Lee, RJ; Morrison, EE; O'Brien, R; Oatey, K; Oosthuyzen, W; Weir, CJ1
Karlsson, JOG1
Dear, JW1
Freeman, WE; Mullins, ME; Yeager, LH1
Akakpo, JY; Jaeschke, H; Ramachandran, A1

Reviews

3 review(s) available for edetic acid and acetaminophen

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Metabolic and mitochondrial treatments for severe paracetamol poisoning: a systematic review.
    Clinical toxicology (Philadelphia, Pa.), 2020, Volume: 58, Issue:12

    Topics: Acetaminophen; Acetylcysteine; Acidosis; Animals; Antidotes; Cimetidine; Drug Overdose; Edetic Acid; Fomepizole; Humans; Mitochondria; Pyridoxal Phosphate

2020
Novel strategies for the treatment of acetaminophen hepatotoxicity.
    Expert opinion on drug metabolism & toxicology, 2020, Volume: 16, Issue:11

    Topics: Acetaminophen; Acetylcysteine; Animals; Antidotes; Chemical and Drug Induced Liver Injury; Drug Overdose; Edetic Acid; Fomepizole; Hepatocytes; Humans; Liver Failure, Acute; Pyridoxal Phosphate

2020

Trials

2 trial(s) available for edetic acid and acetaminophen

ArticleYear
Randomised open label exploratory, safety and tolerability study with calmangafodipir in patients treated with the 12-h regimen of N-acetylcysteine for paracetamol overdose-the PP100-01 for Overdose of Paracetamol (POP) trial: study protocol for a randomi
    Trials, 2019, Jan-08, Volume: 20, Issue:1

    Topics: Acetaminophen; Acetylcysteine; Chemical and Drug Induced Liver Injury; Clinical Trials Data Monitoring Committees; Clinical Trials, Phase I as Topic; Data Interpretation, Statistical; Drug Overdose; Drug Therapy, Combination; Edetic Acid; Female; Humans; Male; Outcome Assessment, Health Care; Pyridoxal Phosphate; Randomized Controlled Trials as Topic; Research Design

2019
Principal results of a randomised open label exploratory, safety and tolerability study with calmangafodipir in patients treated with a 12 h regimen of N-acetylcysteine for paracetamol overdose (POP trial).
    EBioMedicine, 2019, Volume: 46

    Topics: Acetaminophen; Acetylcysteine; Adult; Biomarkers; Chemical and Drug Induced Liver Injury; Drug Interactions; Drug Overdose; Edetic Acid; Female; Humans; Male; Protective Agents; Pyridoxal Phosphate; Time Factors; Young Adult

2019

Other Studies

14 other study(ies) available for edetic acid and acetaminophen

ArticleYear
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:1

    Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics

2011
The effects of cyclic adenosine 3',5'-monophosphate and other adenine nucleotides on body temperature.
    The Journal of physiology, 1975, Volume: 250, Issue:1

    Topics: Acetaminophen; Acetylcholine; Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Body Temperature; Body Temperature Regulation; Bucladesine; Calcium; Cats; Cyclic AMP; Edetic Acid; Female; Hypothalamus; Hypothermia; Norepinephrine; Physostigmine; Preoptic Area; Serotonin

1975
Methyldopa binding to cells in culture.
    Acta pharmacologica et toxicologica, 1977, Volume: 40, Issue:1

    Topics: Acetaminophen; Allopurinol; Animals; Ascorbic Acid; Carcinoma, Hepatocellular; Cells, Cultured; Deferoxamine; Dimethylnitrosamine; Edetic Acid; Furosemide; Glutathione; Liver Neoplasms; Maleates; Methyldopa; Neoplasms, Experimental; Protein Binding; Rats; Superoxide Dismutase; Time Factors; Xanthines

1977
Stabilization by ethylenediaminetetraacetic acid of amide and other groups in drug compounds.
    Journal of clinical pharmacy and therapeutics, 1992, Volume: 17, Issue:2

    Topics: Acetaminophen; Acetanilides; Drug Stability; Edetic Acid; Lidocaine; Sulfadiazine; Sulfathiazoles

1992
Lipid peroxidation, protein synthesis, and protection by calcium EDTA in paracetamol injury to isolated hepatocytes.
    Biochemical pharmacology, 1985, Jan-01, Volume: 34, Issue:1

    Topics: Acetaminophen; Animals; Calcium; Edetic Acid; In Vitro Techniques; Lipid Peroxides; Liver; Male; Protein Biosynthesis; Rats; Rats, Inbred Strains

1985
[Studies on the mechanism of hydroxylation and oxidative O-dealkylation of phenacetin in model systems].
    Biochemical pharmacology, 1967, Volume: 16, Issue:12

    Topics: Acetaminophen; Edetic Acid; Free Radicals; Hydroxides; Iron; Microsomes; Mixed Function Oxygenases; Models, Chemical; NAD; NADP; Phenacetin

1967
Adverse reactions to N-acetylcysteine.
    Human toxicology, 1984, Volume: 3, Issue:5

    Topics: Acetaminophen; Acetylcysteine; Adolescent; Adult; Aged; Edetic Acid; Female; Humans; Male; Skin Tests; Time Factors; Urticaria

1984
Mangafodipir prevents liver injury induced by acetaminophen in the mouse.
    Journal of hepatology, 2003, Volume: 39, Issue:5

    Topics: Acetaminophen; Animals; Antibodies, Monoclonal; Antioxidants; Carcinoma, Hepatocellular; Caspase 3; Caspase Inhibitors; Cell Line, Tumor; Cytochromes c; Edetic Acid; Enzymes; fas Receptor; Female; Glutathione; Humans; Liver; Liver Failure, Acute; Liver Neoplasms; Mice; Mice, Inbred BALB C; Oxidoreductases; Pyridoxal Phosphate; Reactive Oxygen Species; Superoxides; Survival Analysis

2003
Effects of EDTA on signal stability during electrochemical detection of acetaminophen.
    Journal of pharmaceutical and biomedical analysis, 2004, Mar-10, Volume: 34, Issue:5

    Topics: Acetaminophen; Edetic Acid; Electrochemistry; Flow Injection Analysis

2004
Crystal polymorphism of pharmaceuticals: probing crystal nucleation at the molecular level.
    Journal of enzyme inhibition and medicinal chemistry, 2007, Volume: 22, Issue:5

    Topics: Acetaminophen; Chemistry, Pharmaceutical; Crystallization; Crystallography, X-Ray; Edetic Acid; Glutamic Acid; Molecular Structure; Sulfathiazole; Sulfathiazoles

2007
Determination of drug concentrations using dried blood spots: investigation of blood sampling and collection techniques in Crl:CD(SD) rats.
    Laboratory animals, 2011, Volume: 45, Issue:2

    Topics: Acetaminophen; Animals; Area Under Curve; Blood Specimen Collection; Edetic Acid; Male; Pharmaceutical Preparations; Rats; Rats, Inbred Strains

2011
Letter in response to: "Randomised open label exploratory, safety and tolerability study with calmangafodipir in patients treated with the 12-h regimen of N acetylcysteine for paracetamol overdose-the PP100-01 for Overdose of Paracetamol (POP) trial: stud
    Trials, 2019, 06-24, Volume: 20, Issue:1

    Topics: Acetaminophen; Acetylcysteine; Drug Overdose; Edetic Acid; Humans; Pyridoxal Phosphate; Research Design

2019
Gastrointestinal AEs seen in the POP trial due to SOD mimetic activity of calmangafodipir?
    EBioMedicine, 2019, Volume: 47

    Topics: Acetaminophen; Acetylcysteine; Edetic Acid; Humans; Pyridoxal Phosphate; Superoxide Dismutase

2019
Gastrointestinal AEs seen in the POP trial due to SOD mimetic activity of calmangafodipir? - Authors' reply.
    EBioMedicine, 2019, Volume: 47

    Topics: Acetaminophen; Acetylcysteine; Edetic Acid; Humans; Pyridoxal Phosphate; Superoxide Dismutase

2019