edelfosine and tetradecanoylphorbol acetate

edelfosine has been researched along with tetradecanoylphorbol acetate in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19902 (8.33)18.7374
1990's19 (79.17)18.2507
2000's3 (12.50)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Chambers, TC; Kuo, JF; Zheng, B1
Bittman, R; Davenport, R; Dryden, P; Howard, S; Jones, K; Salari, H1
Hoffman, DR; Snyder, F; Thomas, VL1
Berkovic, D; Doenecke, D; Eibl, H; Hochhuth, C; Unger, C1
Heesbeen, EC; Hermans, SW; Rijksen, G; Staal, GE; van Heugten, HG; Verdonck, LF1
Eibl, H; Fleer, EA; Kuo, JF; Raynor, RL; Shoji, M; Vogler, WR1
Iaizzo, PA; Olsen, RA; Powis, G; Seewald, MJ; Sehgal, I1
Daniel, LW; Parker, J; Waite, M1
Daniel, LW; Etkin, LA; Morris-Natschke, S; Morrison, BT; Parker, J; Piantadosi, C; Surles, JR1
Civoli, F; Daniel, LW; Raju, PA; Roederer, M; Rogers, MA; Smitherman, PK1
Berkovic, D; Berkovic, K; Eibl, H; Fleer, EA; Unger, C1
Layne, MD; Modest, EJ; Schreiber, BM1
Berdel, WE; Fukuhara, T; Shoji, M; Vogler, WR; Winton, EF1
Kammer, GM; Laxminarayana, D1
Armant, DR; Stachecki, JJ1
Bjerve, KS; Bleivik, B; White, LR1
Bockman, RS; Rapuano, BE1
Crilly, KS; Kiss, Z1
Bartlett, ST; Kuo, PC; Schroeder, RA1
Civoli, F; Daniel, LW; Whitman, SP1
Civoli, F; Daniel, LW1
Janoff, AS; Mayhew, E; Pushkareva, MY; Wannberg, SL1
Ito, H; Ito, T; Kato, K; Kozawa, O; Matsuno, H; Niwa, M; Sakai, N; Tanabe, K; Uematsu, T1

Other Studies

24 other study(ies) available for edelfosine and tetradecanoylphorbol acetate

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Regulation by phorbol ester and protein kinase C inhibitors, and by a protein phosphatase inhibitor (okadaic acid), of P-glycoprotein phosphorylation and relationship to drug accumulation in multidrug-resistant human KB cells.
    Molecular pharmacology, 1992, Volume: 41, Issue:6

    Topics: Alkaloids; ATP Binding Cassette Transporter, Subfamily B, Member 1; Drug Resistance; Ethers, Cyclic; Humans; KB Cells; Membrane Glycoproteins; Naphthalenes; Okadaic Acid; Peptide Mapping; Phenotype; Phospholipid Ethers; Phosphopeptides; Phosphoprotein Phosphatases; Phosphorylation; Polycyclic Compounds; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Verapamil; Vinblastine

1992
Inhibition of protein kinase C by ether-linked lipids is not correlated with their antineoplastic activity on WEHI-3B and R6X-B15 cells.
    Biochimica et biophysica acta, 1992, Feb-19, Volume: 1134, Issue:1

    Topics: Antineoplastic Agents; Cell Compartmentation; Cell Division; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Phorbol 12,13-Dibutyrate; Phospholipid Ethers; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1992
Inhibition of cellular transport systems by alkyl phospholipid analogs in HL-60 human leukemia cells.
    Biochimica et biophysica acta, 1992, Jul-09, Volume: 1127, Issue:1

    Topics: Antineoplastic Agents; Biological Transport; Cell Line; Cell Survival; Choline; Humans; Leukemia, Promyelocytic, Acute; Monosaccharide Transport Proteins; Phosphatidylcholines; Phospholipid Ethers; Tetradecanoylphorbol Acetate

1992
Effects of antineoplastic phospholipids on parameters of cell differentiation in U937 cells.
    Journal of cancer research and clinical oncology, 1990, Volume: 116, Issue:5

    Topics: Antigens, Surface; Antineoplastic Agents; Blotting, Northern; Cell Transformation, Neoplastic; DNA Probes; Fatty Alcohols; Gene Expression Regulation, Neoplastic; Histones; Leukemia, Promyelocytic, Acute; Lysophosphatidylcholines; Phorbol Esters; Phospholipid Ethers; Phospholipids; Phosphorylcholine; RNA; RNA, Messenger; Tetradecanoylphorbol Acetate

1990
Alkyllysophospholipid ET-18-OCH3 acts as an activator of protein kinase C in HL-60 cells.
    FEBS letters, 1991, Sep-23, Volume: 290, Issue:1-2

    Topics: Cell Membrane; Cytosol; Enzyme Activation; Humans; In Vitro Techniques; Micelles; Phospholipid Ethers; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1991
Effects of hexadecylphosphocholine on protein kinase C and TPA-induced differentiation of HL60 cells.
    Lipids, 1991, Volume: 26, Issue:2

    Topics: Cell Differentiation; Cell Line; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Phospholipid Ethers; Phosphoproteins; Phosphorylation; Phosphorylcholine; Protein Kinase C; Tetradecanoylphorbol Acetate

1991
Platelet-derived growth factor stimulates non-mitochondrial Ca2+ uptake and inhibits mitogen-induced Ca2+ signaling in Swiss 3T3 fibroblasts.
    The Journal of biological chemistry, 1990, Jun-25, Volume: 265, Issue:18

    Topics: Alkaloids; Animals; Biological Transport, Active; Bradykinin; Calcimycin; Calcium; Cells, Cultured; Dinoprostone; Fibroblasts; Ionomycin; Kinetics; Mice; Mitogens; Phospholipid Ethers; Platelet-Derived Growth Factor; Protein Kinase C; Recombinant Proteins; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Vasopressins

1990
Evidence of protein kinase C involvement in phorbol diester-stimulated arachidonic acid release and prostaglandin synthesis.
    The Journal of biological chemistry, 1987, Apr-15, Volume: 262, Issue:11

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Dogs; Dose-Response Relationship, Drug; Enzyme Activation; Indomethacin; Isoquinolines; Kidney; Lysophosphatidylcholines; Molecular Weight; Phospholipid Ethers; Phosphorylation; Piperazines; Prostaglandins; Protein Kinase C; Tetradecanoylphorbol Acetate

1987
Ether lipids inhibit the effects of phorbol diester tumor promoters.
    Lipids, 1987, Volume: 22, Issue:11

    Topics: Animals; Antineoplastic Agents; Carcinogens; Glycerophosphates; Phospholipid Ethers; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1987
ET-18-OCH3 inhibits nuclear factor-kappa B activation by 12-O-tetradecanoylphorbol-13-acetate but not by tumor necrosis factor-alpha or interleukin 1 alpha.
    Cancer research, 1995, Nov-01, Volume: 55, Issue:21

    Topics: Antineoplastic Agents; Auranofin; Carcinogens; Cell Line; Cell Survival; Drug Interactions; Enzyme Inhibitors; Gene Expression; HIV; Humans; Interleukin-1; Kidney; NF-kappa B; Phospholipid Ethers; Protein Kinase C; Repetitive Sequences, Nucleic Acid; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Transfection; Tumor Necrosis Factor-alpha

1995
Inhibition of calcium-dependent protein kinase C by hexadecylphosphocholine and 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine do not correlate with inhibition of proliferation of HL60 and K562 cell lines.
    European journal of cancer (Oxford, England : 1990), 1994, Volume: 30A, Issue:4

    Topics: Antineoplastic Agents; Cell Division; Cell Membrane; Cytosol; Diglycerides; Dose-Response Relationship, Drug; Humans; Leukemia; Phospholipid Ethers; Phosphorylcholine; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1994
Superoxide production by macrophages stimulated in vivo with synthetic ether lipids.
    Lipids, 1994, Volume: 29, Issue:4

    Topics: Animals; Antineoplastic Agents; Cytochrome c Group; Humans; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C57BL; Oxidation-Reduction; Phospholipid Ethers; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1994
Different mechanisms of inhibition by alkyl-lysophospholipid and phorbol ester of granulocyte-macrophage colony-stimulating factor binding to human leukemic cell lines.
    Experimental hematology, 1994, Volume: 22, Issue:1

    Topics: Antineoplastic Agents; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Iodine Radioisotopes; Leukemia; Leukemia, Experimental; Phospholipid Ethers; Protein Binding; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1994
Activation of type I protein kinase A during receptor-mediated human T lymphocyte activation.
    Journal of immunology (Baltimore, Md. : 1950), 1996, Jan-15, Volume: 156, Issue:2

    Topics: Adult; Benzoquinones; Calcium; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Female; GTP-Binding Proteins; Humans; Interleukin-1; Interleukin-2; Isoenzymes; Lactams, Macrocyclic; Leukemia-Lymphoma, Adult T-Cell; Leukocyte Common Antigens; Lymphocyte Activation; Male; Membrane Proteins; Models, Biological; Muromonab-CD3; Phospholipase C gamma; Phospholipid Ethers; Phosphorylation; Protein Kinase C; Protein Processing, Post-Translational; Quinones; Receptor-CD3 Complex, Antigen, T-Cell; Receptors, Antigen, T-Cell, alpha-beta; Receptors, Interleukin-1; Recombinant Proteins; Rifabutin; RNA, Messenger; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thionucleotides; Tumor Cells, Cultured; Type C Phospholipases

1996
Regulation of blastocoele formation by intracellular calcium release is mediated through a phospholipase C-dependent pathway in mice.
    Biology of reproduction, 1996, Volume: 55, Issue:6

    Topics: Animals; Calcium; Calmodulin; Embryonic Development; Enzyme Inhibitors; Estrenes; Ethanol; Female; Inositol 1,4,5-Trisphosphate; Kinetics; Lysophospholipids; Mice; Morula; Phospholipid Ethers; Pregnancy; Protein Kinase C; Pyrrolidinones; Signal Transduction; Tetradecanoylphorbol Acetate; Type C Phospholipases

1996
Protein kinase C inhibitors and PAF stimulate phosphatidylserine synthesis in human leucocytes.
    Journal of lipid mediators and cell signalling, 1996, Volume: 15, Issue:1

    Topics: Antineoplastic Agents; Carbon Radioisotopes; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Female; Humans; Male; Neutrophils; Phosphatidylserines; Phospholipid Ethers; Platelet Activating Factor; Protein Kinase C; Serine; Stimulation, Chemical; Tetradecanoylphorbol Acetate

1996
Protein kinase C-independent activation of a novel nonspecific phospholipase C pathway by phorbol myristate acetate releases arachidonic acid for prostaglandin synthesis in MC3T3-E1 osteoblasts.
    Prostaglandins, 1997, Volume: 53, Issue:3

    Topics: Animals; Arachidonic Acid; Carcinogens; Cell Line; Cyclohexanones; Diglycerides; Dinoprostone; Down-Regulation; Eicosanoids; Enzyme Activation; Lipoprotein Lipase; Membrane Lipids; Mice; Osteoblasts; Phosphatidylethanolamines; Phosphatidylinositols; Phospholipases A; Phospholipases A2; Phospholipid Ethers; Phospholipids; Prostaglandins; Protease Inhibitors; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Type C Phospholipases

1997
Alkyl lysophospholipids inhibit phorbol ester-stimulated phospholipase D activity and DNA synthesis in fibroblasts.
    FEBS letters, 1997, Jul-28, Volume: 412, Issue:2

    Topics: 3T3 Cells; Animals; DNA Replication; Enzyme Activation; Fibroblasts; Mice; Phospholipase D; Phospholipid Ethers; Tetradecanoylphorbol Acetate

1997
Endotoxin-mediated synthesis of nitric oxide is dependent on Gq protein signal transduction.
    Surgery, 1997, Volume: 122, Issue:2

    Topics: Animals; Cell Line; Cholera Toxin; Endotoxins; Enzyme Inhibitors; Escherichia coli; Genistein; GTP-Binding Proteins; Guanosine Diphosphate; Isoflavones; Kinetics; Lipopolysaccharides; Macrophages; Mice; Naphthalenes; Nitric Oxide; Nitric Oxide Synthase; Pertussis Toxin; Phospholipid Ethers; Polymerase Chain Reaction; Protein Kinase C; Protein-Tyrosine Kinases; RNA, Messenger; Signal Transduction; Suramin; Tetradecanoylphorbol Acetate; Thionucleotides; Transcription, Genetic; Type C Phospholipases; Virulence Factors, Bordetella

1997
Protein kinase CbetaII activation by 1-beta-D-arabinofuranosylcytosine is antagonistic to stimulation of apoptosis and Bcl-2alpha down-regulation.
    The Journal of biological chemistry, 1997, Sep-19, Volume: 272, Issue:38

    Topics: Apoptosis; Biological Transport; Cytarabine; DNA Fragmentation; Down-Regulation; Enzyme Activation; HL-60 Cells; Humans; Oligonucleotides, Antisense; Phospholipid Ethers; Protein Kinase C; Protein Kinase C beta; Proto-Oncogene Proteins c-bcl-2; Tetradecanoylphorbol Acetate

1997
Quaternary ammonium analogs of ether lipids inhibit the activation of protein kinase C and the growth of human leukemia cell lines.
    Cancer chemotherapy and pharmacology, 1998, Volume: 42, Issue:4

    Topics: Antineoplastic Agents; Cell Differentiation; Cell Division; Cell Survival; Culture Media, Serum-Free; Drug Resistance; Enzyme Activation; Furans; HL-60 Cells; Humans; Phospholipid Ethers; Phosphorylcholine; Protein Kinase C; Quaternary Ammonium Compounds; Structure-Activity Relationship; Tetradecanoylphorbol Acetate

1998
Increased cell-surface receptor expression on U-937 cells induced by 1-O-octadecyl-2-O-methyl-sn-glycero-3-phosphocholine.
    Cancer immunology, immunotherapy : CII, 2000, Volume: 48, Issue:10

    Topics: Antigens, CD; Antigens, Differentiation, B-Lymphocyte; Antineoplastic Agents; Cell Differentiation; Drug Carriers; Drug Synergism; Humans; Kangai-1 Protein; Liposomes; Lymphoma, Large B-Cell, Diffuse; Macrophage-1 Antigen; Membrane Glycoproteins; Phagocytosis; Phospholipid Ethers; Proto-Oncogene Proteins; Receptors, Cell Surface; Receptors, Transferrin; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Necrosis Factor-alpha; U937 Cells

2000
p38 MAP kinase is required for vasopressin-stimulated HSP27 induction in aortic smooth muscle cells.
    Hypertension (Dallas, Tex. : 1979), 2000, Volume: 35, Issue:2

    Topics: Animals; Aorta; Arginine Vasopressin; Cell Line; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation; Imidazoles; Immunoassay; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Naphthalenes; Neoplasm Proteins; p38 Mitogen-Activated Protein Kinases; Phospholipid Ethers; Phosphorylation; Protein Kinase C; Pyridines; RNA, Messenger; Tetradecanoylphorbol Acetate; Vasopressins

2000