edelfosine has been researched along with lysophosphatidylcholines in 39 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 27 (69.23) | 18.7374 |
| 1990's | 8 (20.51) | 18.2507 |
| 2000's | 1 (2.56) | 29.6817 |
| 2010's | 2 (5.13) | 24.3611 |
| 2020's | 1 (2.56) | 2.80 |
| Authors | Studies |
|---|---|
| Berkovic, D; Doenecke, D; Eibl, H; Hochhuth, C; Unger, C | 1 |
| Eibl, H; Krisch, B; Nagel, GA; Unger, C; von Heyden, HW | 1 |
| Colvin, OM; Santos, GW | 1 |
| Girard, PR; Kuo, JF; Mazzei, GJ; Shoji, M; Su, HD; Turner, RS | 1 |
| Eibl, H; Kim, DJ; Nagel, GA; Unger, C; Vehmeyer, K | 1 |
| Kuo, JF; Oishi, K; Vogler, WR; White, JF; Zheng, B | 1 |
| Berger, MR; Schmähl, D | 1 |
| Daniel, LW; Parker, J; Waite, M | 1 |
| Bartsch, HH; Eibl, H; Fleer, EA; Kim, DJ; Kötting, J; Nagel, GA; Pfizenmaier, K; Unger, C | 1 |
| Okamoto, S; Olson, AC; Vogler, WR | 1 |
| Berdel, WE; Eibl, H; Fink, U; Rastetter, J; Reichert, A; Schick, HD; Unger, C; Von Hoff, DD | 1 |
| Hoffman, DR; Hoffman, LH; Snyder, F | 1 |
| Cordeiro, RS; Henriques, MG; Martins, MA; Silva, PM; Vargaftig, BB | 1 |
| Bennett, WD; Olson, AC; Vogler, WR; Whigham, E | 1 |
| Andreesen, R; Dulisch, I; Löhr, GW; Neumann, HA | 1 |
| Jann, K; Munder, PG; Vassilev, TL | 1 |
| Ferber, E; Herrmann, DB; Munder, PG | 1 |
| Berdel, WE; Roos, G | 1 |
| Berdel, WE; Bruyneel, EA; De Bruyne, GK; Mareel, MM; Storme, GA; van Blitterswijk, WJ | 1 |
| Glasser, L; Somberg, LB; Vogler, WR | 1 |
| Berger, MR; Munder, PG; Schmähl, D; Westphal, O | 1 |
| Long, RC; Somberg, LB; Vogler, WR; Whigham, EA; Winton, EF | 1 |
| Andreesen, R; Costabel, U; Löhr, GW; Luckenbach, GA; Munder, PG; Osterholz, J; Schulz, A; Speth, V | 1 |
| Bador, H; Louisot, P; Morelis, R | 1 |
| Berdel, WE; Fink, U; Gössner, W; Luz, A; Messerschmidt, O; Rastetter, J | 1 |
| Berdel, WE; Eckhardt, K; Gocke, E; King, MT; Munder, PG; Wild, D | 1 |
| Andreesen, R; Evers, P; Maistry, L; Munder, PG; Robinson, KM | 1 |
| Bausert, WR; Berdel, WE; Modolell, ML; Munder, PG; Weltzien, HU; Widmann, KH | 1 |
| Borel, JF; Chabannes, D; Kovarik, J | 1 |
| Boggs, KP; Jackowski, S; Rock, CO | 2 |
| Layne, MD; Modest, EJ; Zoeller, RA | 1 |
| Baburina, I; Jackowski, S | 1 |
| Boggs, K; Jackowski, S; Rock, CO | 1 |
| Janoff, AS; Mayhew, E; Pushkareva, MY | 1 |
| Birchmore, JL; Hanson, PK; Malone, L; Nichols, JW | 1 |
| Krishnaiah, S; Tambellini, NP; Turner, RJ; Weljie, AM; Zaremberg, V | 1 |
| Coorssen, JR; Dabral, D | 1 |
| Dahlström, M; Hamakubo, T; Hamano, F; Ishii, S; Kobayashi, D; Masuda, K; Sato, N; Shimizu, T; Yasuda, D | 1 |
1 review(s) available for edelfosine and lysophosphatidylcholines
| Article | Year |
|---|---|
Pharmacological purging of bone marrow with reference to autografting.
Topics: Adolescent; Adult; Animals; Bleomycin; Bone Marrow; Bone Marrow Transplantation; Cell Separation; Child; Child, Preschool; Clinical Trials as Topic; Cyclophosphamide; Drug Evaluation; Etoposide; Graft vs Host Disease; Hematopoietic Stem Cells; Humans; Leukemia; Leukemia, Lymphoid; Lymphoma; Lysophosphatidylcholines; Methylprednisolone; Neoplasms, Experimental; Phospholipid Ethers; Pyrimidinones; Transplantation, Autologous; Transplantation, Isogeneic | 1986 |
1 trial(s) available for edelfosine and lysophosphatidylcholines
| Article | Year |
|---|---|
Pharmacological purging of bone marrow with reference to autografting.
Topics: Adolescent; Adult; Animals; Bleomycin; Bone Marrow; Bone Marrow Transplantation; Cell Separation; Child; Child, Preschool; Clinical Trials as Topic; Cyclophosphamide; Drug Evaluation; Etoposide; Graft vs Host Disease; Hematopoietic Stem Cells; Humans; Leukemia; Leukemia, Lymphoid; Lymphoma; Lysophosphatidylcholines; Methylprednisolone; Neoplasms, Experimental; Phospholipid Ethers; Pyrimidinones; Transplantation, Autologous; Transplantation, Isogeneic | 1986 |
38 other study(ies) available for edelfosine and lysophosphatidylcholines
| Article | Year |
|---|---|
Effects of antineoplastic phospholipids on parameters of cell differentiation in U937 cells.
Topics: Antigens, Surface; Antineoplastic Agents; Blotting, Northern; Cell Transformation, Neoplastic; DNA Probes; Fatty Alcohols; Gene Expression Regulation, Neoplastic; Histones; Leukemia, Promyelocytic, Acute; Lysophosphatidylcholines; Phorbol Esters; Phospholipid Ethers; Phospholipids; Phosphorylcholine; RNA; RNA, Messenger; Tetradecanoylphorbol Acetate | 1990 |
[Blood-brain barrier and the penetration of cytostatic drugs].
Topics: Animals; Anthraquinones; Antineoplastic Agents; Biological Availability; Bleomycin; Blood-Brain Barrier; Brain; Butanols; Capillary Permeability; Carbon Radioisotopes; Diglycerides; Doxorubicin; Lysophosphatidylcholines; Methotrexate; Mitoxantrone; Phospholipid Ethers; Rats; Tritium | 1985 |
Phospholipid/calcium-dependent protein kinase (protein kinase C) system: a major site of bioregulation.
Topics: Animals; Antineoplastic Agents; Electrophoresis, Polyacrylamide Gel; Estrogen Antagonists; Humans; Kinetics; Leukemia, Experimental; Lysophosphatidylcholines; Microscopy, Electron; Myelin Basic Protein; Peptides; Phospholipid Ethers; Protein Kinase C; Rats; Substrate Specificity | 1986 |
Effect of ether lipids on mouse granulocyte-macrophage progenitor cells.
Topics: Animals; Antineoplastic Agents; Bone Marrow; Bone Marrow Cells; Cell Division; Cells, Cultured; Female; Hematopoietic Stem Cells; Leukocyte Count; Lysophosphatidylcholines; Mice; Phospholipid Ethers; Phosphorylcholine | 1989 |
Inhibition of Na,K-ATPase and sodium pump by anticancer ether lipids and protein kinase C inhibitors ET-18-OCH3 and BM 41.440.
Topics: Animals; Antineoplastic Agents; Cell Membrane; Cerebral Cortex; Erythrocytes; Humans; Leukemia; Lysophosphatidylcholines; Ouabain; Phospholipid Ethers; Protein Kinase C; Rats; Sodium Channels; Sodium Radioisotopes; Sodium-Potassium-Exchanging ATPase; Synaptosomes; Tumor Cells, Cultured | 1988 |
Protection by the alkyllysophospholipid, 1-octadecyl-2-methoxy-rac-glycero-3-phosphocholine, but not by the retinoid etretinate against leukemia development in DMBA-treated Long-Evans rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Etretinate; Female; Leukemia, Experimental; Lysophosphatidylcholines; Lysophospholipids; Male; Mammary Neoplasms, Experimental; Phospholipid Ethers; Phospholipids; Rats | 1986 |
Evidence of protein kinase C involvement in phorbol diester-stimulated arachidonic acid release and prostaglandin synthesis.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Dogs; Dose-Response Relationship, Drug; Enzyme Activation; Indomethacin; Isoquinolines; Kidney; Lysophosphatidylcholines; Molecular Weight; Phospholipid Ethers; Phosphorylation; Piperazines; Prostaglandins; Protein Kinase C; Tetradecanoylphorbol Acetate | 1987 |
Sensitivity of leukemia cell lines to cytotoxic alkyl-lysophospholipids in relation to O-alkyl cleavage enzyme activities.
Topics: Animals; Antineoplastic Agents; Cell Division; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Humans; Hydrolases; Leukemia; Leukemia L1210; Lysophosphatidylcholines; Mice; Phosphatidylcholines; Phospholipid Ethers; Phospholipids | 1987 |
Elimination of leukemic cells by the combined use of ether lipids in vitro.
Topics: Blood; Cell Line; Cell Survival; Clone Cells; Drug Synergism; Humans; In Vitro Techniques; Leukemia, Myeloid, Acute; Lysophosphatidylcholines; Phospholipid Ethers; Piperidines; Stem Cells; Temperature | 1987 |
Ether lipid derivatives: antineoplastic activity in vitro and the structure-activity relationship.
Topics: Antineoplastic Agents; Cell Survival; Female; Humans; Lysophosphatidylcholines; Neoplasms; Phospholipid Ethers; Piperidines; Structure-Activity Relationship | 1986 |
Cytotoxicity and metabolism of alkyl phospholipid analogues in neoplastic cells.
Topics: Animals; Antineoplastic Agents; Cell Line; Cell Membrane; Dogs; Humans; Lysophosphatidylcholines; Microsomes, Liver; Mixed Function Oxygenases; Phospholipid Ethers; Platelet Activating Factor; Rats; Substrate Specificity | 1986 |
Platelet involvement in rat paw edema induced by 2-methoxy-PAF.
Topics: Animals; Blood Platelets; Edema; Female; Lysophosphatidylcholines; Male; Phospholipid Ethers; Platelet Activating Factor; Rabbits; Rats; Rats, Inbred Strains; Time Factors | 1986 |
Effect of alkyl-lysophospholipids on phosphatidylcholine biosynthesis in leukemic cell lines.
Topics: Carbon Radioisotopes; Cell Line; Choline; Humans; Leukemia, Myeloid; Lysophosphatidylcholines; Methionine; Phosphatidylcholines; Phospholipid Ethers; Phospholipids | 1985 |
Clonogenicity of normal and malignant hematopoietic progenitor cells after exposure to synthetic alkyl-lymphospholipids.
Topics: Animals; Antineoplastic Agents; Cell Line; Dose-Response Relationship, Drug; Hematopoiesis; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid, Acute; Lysophosphatidylcholines; Lysophospholipids; Mice; Phospholipid Ethers; Phospholipids | 1985 |
Effect of a lysolecithin analogue on nonspecific resistance to infection of mice.
Topics: Animals; Brain; Immunity, Innate; Kidney; Lysophosphatidylcholines; Lysosomes; Macrophages; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Phagocytosis; Phospholipid Ethers; Salmonella Infections, Animal; Salmonella typhimurium; Sepsis; Spleen | 1985 |
Ether phospholipids as inhibitors of the arachidonoyl-CoA: 1-acyl-sn-glycero-3-phosphocholine acyltransferase in macrophages.
Topics: 1-Acylglycerophosphocholine O-Acyltransferase; Acyl Coenzyme A; Acylation; Acyltransferases; Animals; Dose-Response Relationship, Drug; Female; Kinetics; Lysophosphatidylcholines; Macrophages; Mice; Phospholipid Ethers; Phospholipids; Platelet Activating Factor | 1986 |
Sensitivity of human hematopoietic cell lines to an alkyl-lysophospholipid-derivative.
Topics: Cell Cycle; Cell Division; Cell Line; Cell Survival; DNA, Neoplasm; Hematopoietic Stem Cells; Humans; Kinetics; Leukemia; Lymphoma; Lysophosphatidylcholines; Phospholipid Ethers | 1986 |
Antiinvasive effect of racemic 1-O-octadecyl-2-O-methylglycero-3-phosphocholine on MO4 mouse fibrosarcoma cells in vitro.
Topics: Animals; Cell Division; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Chickens; Drug Evaluation, Preclinical; Fibrosarcoma; Lung Neoplasms; Lysophosphatidylcholines; Membrane Fluidity; Mice; Mice, Inbred C3H; Muscular Diseases; Neoplasm Invasiveness; Phospholipid Ethers; Stereoisomerism; Tubulin | 1985 |
Purging murine leukemic marrow with alkyl-lysophospholipids.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Bone Marrow Transplantation; Colony-Forming Units Assay; Graft vs Host Disease; Leukemia, Experimental; Lysophosphatidylcholines; Lysophospholipids; Mice; Phospholipid Ethers; Phospholipids | 1984 |
Influence of the alkyllysophospholipid ET-18-OCH3 on methylnitrosourea-induced rat mammary carcinomas.
Topics: Animals; Antineoplastic Agents; Body Weight; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Lysophosphatidylcholines; Mammary Neoplasms, Experimental; Methylnitrosourea; Nitrosourea Compounds; Phospholipid Ethers; Rats; Rats, Inbred Strains; Time Factors | 1984 |
The effect of alkyl-lysophospholipids on tritiated thymidine incorporation and clonogenicity in vitro of normal and leukemic human cells.
Topics: Bone Marrow Cells; Cell Line; Circadian Rhythm; Colony-Forming Units Assay; Humans; Leukemia; Lysophosphatidylcholines; Phospholipid Ethers; Thymidine; Time Factors; Tritium; Tumor Stem Cell Assay | 1984 |
Tumor cytotoxicity of human macrophages after incubation with synthetic analogues of 2-lysophosphatidylcholine.
Topics: Antineoplastic Agents; Cell Line; Cytotoxicity, Immunologic; Humans; In Vitro Techniques; Lymphoma; Lysophosphatidylcholines; Macrophage Activation; Macrophages; Phospholipid Ethers; Platelet Activating Factor | 1984 |
Biochemical evidence for the role of alkyl-lysophospholipids on liver sialyltransferase.
Topics: Animals; Antineoplastic Agents; Dose-Response Relationship, Drug; Kinetics; Liver; Lysophosphatidylcholines; Lysophospholipids; Mice; Mice, Inbred Strains; Phospholipid Ethers; Phospholipids; Sialyltransferases; Structure-Activity Relationship; Transferases | 1983 |
Alkyl-lysophospholipids lack influence on the occurrence of radiation-induced lymphomas and AKR-leukemia.
Topics: Animals; Female; Leukemia, Radiation-Induced; Lymphoma; Lysophosphatidylcholines; Male; Mice; Mice, Inbred AKR; Neoplasms, Radiation-Induced; Phospholipid Ethers; Time Factors | 1983 |
Failure to detect mutagenic effects of anti-tumor alkyl-lysophospholipids.
Topics: Animals; Antineoplastic Agents; Bone Marrow; Drosophila melanogaster; Female; Genes, Recessive; Lysophosphatidylcholines; Male; Mice; Mutagenicity Tests; Mutagens; Phospholipid Ethers; Salmonella typhimurium | 1981 |
Morphological effects of an antitumor agent on human esophageal carcinoma cells in vitro.
Topics: Carcinoma; Cell Line; Cell Membrane; Drug Evaluation, Preclinical; Esophageal Neoplasms; Humans; Lysophosphatidylcholines; Membrane Lipids; Microvilli; Mitosis; Phospholipid Ethers; Phospholipids | 1980 |
The influence of alkyl-lysophospholipids and lysophospholipid-activated macrophages on the development of metastasis of 3-Lewis lung carcinoma.
Topics: Animals; Female; Lung Neoplasms; Lysophosphatidylcholines; Macrophages; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Phospholipid Ethers; Transplantation, Isogeneic | 1980 |
Immunoregulation and drug treatment in chronic relapsing experimental allergic encephalomyelitis in the Lewis rat.
Topics: Animals; Autoimmune Diseases; Concanavalin A; Corticosterone; Cyclosporine; Dexamethasone; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Furans; Guinea Pigs; Lymph Nodes; Lymphocyte Activation; Lysophosphatidylcholines; Multiple Sclerosis; Myelin Basic Protein; Phospholipid Ethers; Rats; Rats, Inbred Lew; Tuberculin | 1995 |
Lysophosphatidylcholine and 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine inhibit the CDP-choline pathway of phosphatidylcholine synthesis at the CTP:phosphocholine cytidylyltransferase step.
Topics: Animals; Antineoplastic Agents; Cell Line; Choline; Choline Kinase; Cytidine Diphosphate Choline; Dose-Response Relationship, Drug; Kinetics; Lysophosphatidylcholines; Macrophages; Mice; Nucleotidyltransferases; Phosphatidylcholines; Phospholipid Ethers; RNA Nucleotidyltransferases | 1995 |
Lysophosphatidylcholine attenuates the cytotoxic effects of the antineoplastic phospholipid 1-O-octadecyl-2-O-methyl-rac-glycero-3- phosphocholine.
Topics: Animals; Antineoplastic Agents; Cell Cycle; Cell Division; Cell Line; Cell Survival; Kinetics; Lysophosphatidylcholines; Macrophages; Mice; Mice, Inbred Strains; Phospholipid Ethers; Simian virus 40; Time Factors; Transfection | 1995 |
Animal cell mutants unable to take up biologically active glycerophospholipids.
Topics: Animals; Cell Line; Drug Resistance; Endocytosis; Glycerophosphates; Glycerylphosphorylcholine; Lysophosphatidylcholines; Lysophospholipids; Macrophages; Mice; Mutation; Phosphatidic Acids; Phospholipid Ethers | 1995 |
Apoptosis triggered by 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine is prevented by increased expression of CTP:phosphocholine cytidylyltransferase.
Topics: Antineoplastic Agents; Apoptosis; Choline-Phosphate Cytidylyltransferase; Drug Interactions; Drug Resistance, Neoplasm; HeLa Cells; Humans; Lysophosphatidylcholines; Phospholipid Ethers; Promoter Regions, Genetic | 1998 |
The antiproliferative effect of hexadecylphosphocholine toward HL60 cells is prevented by exogenous lysophosphatidylcholine.
Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Division; Cell Survival; Choline; Choline-Phosphate Cytidylyltransferase; Cytidine Diphosphate Choline; DNA Fragmentation; Enzyme Inhibitors; Flow Cytometry; HL-60 Cells; Humans; Lysophosphatidylcholines; Phosphatidylcholines; Phospholipid Ethers; Phospholipids; Phosphorylcholine; Recombinant Proteins | 1998 |
Inhibition of cell division but not nuclear division by 1-O- octadecyl-2-O-methyl-Sn-glycero-3-phosphocholine.
Topics: 3T3 Cells; Animals; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Division; Cell Nucleus; Cyclin B; Cyclin B1; DNA Fragmentation; Dose-Response Relationship, Drug; Humans; Liposomes; Lysophosphatidylcholines; Mice; Mitosis; Phospholipid Ethers; Tumor Cells, Cultured | 1999 |
Lem3p is essential for the uptake and potency of alkylphosphocholine drugs, edelfosine and miltefosine.
Topics: Alleles; Antiprotozoal Agents; Biological Transport; Cell Division; Cell Membrane; Cycloheximide; Dose-Response Relationship, Drug; Drug Resistance; Drug Resistance, Multiple; Endocytosis; Gene Deletion; Ketoconazole; Leishmaniasis; Lipid Metabolism; Lysophosphatidylcholines; Membrane Transport Proteins; Microscopy, Fluorescence; Mutation; Nuclear Envelope; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylserines; Phosphodiesterase Inhibitors; Phospholipid Ethers; Phosphorylcholine; Point Mutation; Protein Structure, Tertiary; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Time Factors | 2003 |
Primary Metabolism and Medium-Chain Fatty Acid Alterations Precede Long-Chain Fatty Acid Changes Impacting Neutral Lipid Metabolism in Response to an Anticancer Lysophosphatidylcholine Analogue in Yeast.
Topics: Citric Acid Cycle; Dietary Fats; Fatty Acids; Fatty Acids, Nonesterified; Lipid Metabolism; Lysophosphatidylcholines; Metabolomics; Oxidative Stress; Phospholipid Ethers; Saccharomyces cerevisiae | 2017 |
Arachidonic acid and lysophosphatidylcholine inhibit multiple late steps of regulated exocytosis.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Anthocidaris; Arachidonic Acid; Exocytosis; In Vitro Techniques; Lysophosphatidylcholines; Membrane Fusion; Phospholipases A2; Phospholipid Ethers; Secretory Vesicles | 2019 |
Inverse agonism of lysophospholipids with cationic head groups at Gi-coupled receptor GPR82.
Topics: Animals; Drug Inverse Agonism; Ligands; Lysophosphatidylcholines; Lysophospholipids; Mice; Phosphorylcholine | 2023 |