edatrexate has been researched along with trimetrexate in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (90.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bader, H; Keyomarsi, K; Matherly, LH; Rosowsky, A; Wright, JE | 1 |
| Bertino, JR; Brennan, MF; Li, WW; Lin, JT; Tong, WP; Trippett, TM | 1 |
| Yoshimura, A | 1 |
| Fleming, GF; Schilsky, RL | 1 |
| Bertino, JR; Li, WW; Lin, JT; Schweitzer, BI | 1 |
| Bertino, JR; Chang, YM; Li, WW; Lin, JT; Schweitzer, B | 1 |
| Tsukagoshi, S | 1 |
| Allegra, CJ; Takimoto, CH | 1 |
| Blakley, RL; Lewis, WS; Mareya, SM; Patel, M; Sleep, SE; Sorrentino, BP; Spencer, HT | 1 |
| Strømhaug, A; Warren, DJ | 1 |
4 review(s) available for edatrexate and trimetrexate
| Article | Year |
|---|---|
[New analogues of methotrexate].
Topics: Aminopterin; Animals; Antineoplastic Agents; Drug Administration Schedule; Female; Humans; Lung Neoplasms; Male; Methotrexate; Trimetrexate | 1992 |
Antifolates: the next generation.
Topics: Aminopterin; Animals; Antineoplastic Agents; Chemistry, Pharmaceutical; Clinical Trials as Topic; Drug Evaluation; Folic Acid Antagonists; Forecasting; Humans; Neoplasms; Pyrimidines; Quinazolines; Tetrahydrofolates; Thiophenes; Trimetrexate | 1992 |
[Development of antimetabolites, II].
Topics: Aminopterin; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Cytarabine; Deoxycytidine; Humans; Leukemia L1210; Methotrexate; Mice; Trimetrexate | 1993 |
New antifolates in clinical development.
Topics: Aminopterin; Antimetabolites, Antineoplastic; Antineoplastic Agents; Drugs, Investigational; Folic Acid Antagonists; Humans; Neoplasms; Pyrimidines; Quinazolines; Thiophenes; Trimetrexate | 1995 |
6 other study(ies) available for edatrexate and trimetrexate
| Article | Year |
|---|---|
Synthesis and biological activity of N omega-hemiphthaloyl-alpha,omega- diaminoalkanoic acid analogues of aminopterin and 3',5-dichloroaminopterin.
Topics: Aminopterin; Animals; Antineoplastic Agents; Cell Division; Folic Acid Antagonists; Humans; Methotrexate; Mice; Ornithine; Pterins; Structure-Activity Relationship; Tumor Cells, Cultured | 1994 |
Mechanisms of natural resistance to antifolates in human soft tissue sarcomas.
Topics: Aminopterin; Chromatography, High Pressure Liquid; Drug Resistance; Folic Acid Antagonists; Humans; Methotrexate; Peptide Synthases; Polyglutamic Acid; Sarcoma; Soft Tissue Neoplasms; Tetrahydrofolate Dehydrogenase; Thymidylate Synthase; Trimetrexate; Tumor Stem Cell Assay | 1992 |
Mechanisms of sensitivity and natural resistance to antifolates in a methylcholanthrene-induced rat sarcoma.
Topics: Aminopterin; Animals; Drug Resistance; Folic Acid Antagonists; Leucovorin; Methotrexate; Methylcholanthrene; Polyglutamic Acid; Rats; Sarcoma, Experimental; Tetrahydrofolate Dehydrogenase; Trimetrexate; Tumor Cells, Cultured | 1991 |
Prediction of antifolate efficacy in a rat sarcoma model.
Topics: Aminopterin; Animals; Drug Screening Assays, Antitumor; Folic Acid Antagonists; Male; Methotrexate; Methylcholanthrene; Quinazolines; Rats; Sarcoma, Experimental; Thymidylate Synthase; Trimetrexate | 1991 |
Comparison of the protection of cells from antifolates by transduced human dihydrofolate reductase mutants.
Topics: Aminopterin; Animals; Cell Survival; Drug Resistance, Neoplasm; Folic Acid Antagonists; Gene Expression; Genetic Variation; Growth Inhibitors; Humans; Kinetics; Methotrexate; Pyrimidines; Rabbits; Tetrahydrofolate Dehydrogenase; Thymidine; Transfection; Trimetrexate | 1997 |
A comparison of the effects of nine folate analogs on early and late murine hematopoietic progenitor cells in vitro.
Topics: Aminopterin; Animals; Cell Division; Cells, Cultured; Enzyme Inhibitors; Female; Folic Acid; Folic Acid Antagonists; Hematopoietic Stem Cells; Methotrexate; Mice; Mice, Inbred BALB C; Quinazolines; Tetrahydrofolates; Thiophenes; Trimetrexate | 2000 |