edatrexate has been researched along with carboplatin in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (66.67) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Benner, SE; Dimery, IW; Esparaz, B; Frenning, D; Guillory-Perez, C; Hong, WK; Huber, MH; Lippman, SM; Shirinian, M | 1 |
| Chou, TC; Fletcher, TS; Hack, FM; Perez, EA | 1 |
| Crowley, JJ; Edelman, MJ; Gandara, DR; Lau, DH; Livingston, RB | 1 |
| Edelman, MJ; Gandara, DR; Lau, D; Lauder, I; Meyers, F; Perez, EA; Turrell, C; Uhrich, M | 1 |
| Kris, MG; Miller, VA; Scher, HI; Sirotnak, FM; Zakowski, MF | 1 |
| Khokhar, NZ; Rusch, VW; She, Y; Sirotnak, FM | 1 |
3 trial(s) available for edatrexate and carboplatin
| Article | Year |
|---|---|
Phase II study of carboplatin and edatrexate (10-EdAM) with leucovorin rescue for patients with recurrent squamous cell carcinoma of the head and neck.
Topics: Adult; Aged; Aminopterin; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Leucovorin; Male; Middle Aged; Neoplasm Recurrence, Local | 1994 |
Phase II trial of edatrexate plus carboplatin in metastatic non-small-cell lung cancer: a Southwest Oncology Group study.
Topics: Adult; Aged; Aminopterin; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Non-Small-Cell Lung; Drug Administration Schedule; Female; Humans; Lung Neoplasms; Male; Middle Aged; Mouth Mucosa; Neutropenia; Survival Analysis; Treatment Outcome | 1997 |
Phase I trial of edatrexate plus carboplatin in advanced solid tumors: amelioration of dose-limiting mucositis by ice chip cryotherapy.
Topics: Adult; Aged; Aminopterin; Anemia; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cryotherapy; Exanthema; Female; Humans; Leukopenia; Male; Middle Aged; Mucous Membrane; Neoplasms; Vomiting | 1998 |
3 other study(ies) available for edatrexate and carboplatin
| Article | Year |
|---|---|
Modulation of intrinsic in vitro resistance to carboplatin by edatrexate in the A549 human nonsmall cell lung cancer cell line.
Topics: Aminopterin; Antineoplastic Agents; Carboplatin; Carcinoma, Non-Small-Cell Lung; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Drug Interactions; Drug Resistance; Humans; Kinetics; Lung Neoplasms; Time Factors; Tumor Cells, Cultured | 1994 |
Efficacy of cytotoxic agents against human tumor xenografts is markedly enhanced by coadministration of ZD1839 (Iressa), an inhibitor of EGFR tyrosine kinase.
Topics: Aminopterin; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Carboplatin; Cell Division; Cisplatin; Docetaxel; Dose-Response Relationship, Drug; ErbB Receptors; Female; Gefitinib; Humans; Immunohistochemistry; Lung Neoplasms; Male; Maximum Tolerated Dose; Mice; Mice, Nude; Neoplasm Transplantation; Paclitaxel; Prostatic Neoplasms; Quinazolines; Reverse Transcriptase Polymerase Chain Reaction; Taxoids; Time Factors; Tumor Cells, Cultured; Vinblastine; Vinorelbine; Vulvar Neoplasms | 2000 |
Experimental therapeutics with a new 10-deazaaminopterin in human mesothelioma: further improving efficacy through structural design, pharmacologic modulation at the level of MRP ATPases, and combined therapy with platinums.
Topics: Adenosine Triphosphatases; Aminopterin; Animals; Anion Transport Proteins; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cell Cycle Proteins; Cell Division; Cisplatin; Drug Design; Fungal Proteins; Gene Expression Regulation, Neoplastic; Humans; Inhibitory Concentration 50; Mesothelioma; Methotrexate; Mice; Mice, Nude; Multidrug Resistance-Associated Proteins; Platinum Compounds; Protein Isoforms; Protein Kinases; RNA, Neoplasm; Schizosaccharomyces pombe Proteins; Treatment Outcome; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2001 |