edatrexate has been researched along with 10-deazaaminopterin in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (50.00) | 18.7374 |
| 1990's | 5 (41.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abraham, A; Galivan, J; Gaumont, Y; Kisliuk, RL; McGuire, JJ; Nair, MG; Nimec, Z | 1 |
| Christie, PH; DeGraw, JI; Gaumont, Y; Kisliuk, RL; Sirotnak, FM | 1 |
| Gaumont, Y; Kisliuk, RL; Kumar, P; Nair, MG; Nanavati, NT | 1 |
| Colwell, WT; DeGraw, JI; Piper, JR; Sirotnak, FM | 2 |
| Colwell, WT; Crase, J; DeGraw, JI; Piper, JR; Sirotnak, FM; Smith, RL; Waud, WR | 1 |
| Barnes, SW; Bonamy, GM; Bopp, SE; Borboa, R; Bright, AT; Chatterjee, A; Che, J; Cohen, S; Dharia, NV; Diagana, TT; Fidock, DA; Froissard, P; Gagaring, K; Gettayacamin, M; Glynne, RJ; Gordon, P; Groessl, T; Kato, N; Kuhen, KL; Lee, MC; Mazier, D; McNamara, CW; Meister, S; Nagle, A; Nam, TG; Plouffe, DM; Richmond, W; Roland, J; Rottmann, M; Sattabongkot, J; Schultz, PG; Tuntland, T; Walker, JR; Winzeler, EA; Wu, T; Zhou, B; Zhou, Y | 1 |
| Fanucchi, MP; Farag, F; Kinahan, JJ; Samuels, LL; Sirotnak, FM; Vidal, PM; Young, CW | 1 |
| Freisheim, JH; Gaumont, Y; Kisliuk, RL; Kumar, P; Nair, MG | 1 |
| Moccio, DM; Samuels, LL; Sirotnak, FM | 1 |
| DeGraw, JI; Goutas, LJ; Moccio, DM; Samuels, LL; Sirotnak, FM | 1 |
| DeGraw, JI; Goutas, LJ; Moccio, DM; Schmid, FA; Sirotnak, FM | 1 |
12 other study(ies) available for edatrexate and 10-deazaaminopterin
| Article | Year |
|---|---|
Folate analogues. 34. Synthesis and antitumor activity of non-polyglutamylatable inhibitors of dihydrofolate reductase.
Topics: Animals; Antimetabolites, Antineoplastic; Cell Division; Cell Line; Drug Screening Assays, Antitumor; Folic Acid Antagonists; Humans; Indicators and Reagents; Methotrexate; Molecular Structure; Recombinant Proteins; Structure-Activity Relationship | 1991 |
Synthesis and antifolate properties of 9-alkyl-10-deazaminopterins.
Topics: Aminopterin; Animals; Chemical Phenomena; Chemistry; Folic Acid Antagonists; Humans; Leukemia; Leukemia L1210; Methotrexate; Molecular Structure; Tumor Cells, Cultured | 1990 |
Synthesis and biological evaluation of poly-gamma-glutamyl metabolites of 10-deazaaminopterin and 10-ethyl-10-deazaaminopterin.
Topics: Aminopterin; Animals; Anti-Bacterial Agents; Female; Folic Acid Antagonists; gamma-Glutamyl Hydrolase; Humans; Lacticaseibacillus casei; Methotrexate; Mice; Mice, Inbred Strains; Microbial Sensitivity Tests; Peptides; Polyglutamic Acid; Streptococcus; Structure-Activity Relationship; Substrate Specificity | 1988 |
Synthesis and antitumor activity of 10-propargyl-10-deazaaminopterin.
Topics: Aminopterin; Animals; Antineoplastic Agents; Female; Leukemia L1210; Mammary Neoplasms, Experimental; Mice; Structure-Activity Relationship | 1993 |
Analogues of methotrexate in rheumatoid arthritis. 1. Effects of 10-deazaaminopterin analogues on type II collagen-induced arthritis in mice.
Topics: Aminopterin; Animals; Antirheumatic Agents; Arthritis, Rheumatoid; Cell Line; Cell Survival; Collagen; Humans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Methotrexate; Mice; Molecular Structure; Tumor Cells, Cultured | 1997 |
Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery.
Topics: Animals; Antimalarials; Cell Line, Tumor; Drug Discovery; Drug Evaluation, Preclinical; Drug Resistance; Erythrocytes; Humans; Imidazoles; Liver; Malaria; Mice; Mice, Inbred BALB C; Molecular Structure; Piperazines; Plasmodium; Plasmodium berghei; Plasmodium falciparum; Plasmodium yoelii; Polymorphism, Single Nucleotide; Protozoan Proteins; Random Allocation; Small Molecule Libraries; Sporozoites | 2011 |
Fluorometric high-performance liquid chromatographic analysis of 10-deazaaminopterin, 10-ethyl-10-deazaaminopterin, and known metabolites.
Topics: Aminopterin; Animals; Chromatography, High Pressure Liquid; Humans; Leukemia L1210; Mice; Mice, Nude; Neoplasms; Polyglutamic Acid; Spectrometry, Fluorescence | 1985 |
Inhibition of human dihydrofolate reductase by antifolyl polyglutamates.
Topics: Aminopterin; Folic Acid Antagonists; Humans; Methotrexate; Peptides; Polyglutamic Acid | 1989 |
Similar differential for total polyglutamylation and cytotoxicity among various folate analogues in human and murine tumor cells in vitro.
Topics: Aminopterin; Animals; Cells, Cultured; Folic Acid; Humans; Kinetics; Leukemia L1210; Methotrexate; Mice; Neoplasms; Pteroylpolyglutamic Acids; Tumor Stem Cell Assay | 1985 |
New folate analogs of the 10-deaza-aminopterin series. Basis for structural design and biochemical and pharmacologic properties.
Topics: Aminopterin; Animals; Cells, Cultured; Epithelium; Female; Folic Acid Antagonists; Intestine, Small; Kinetics; Mice; Structure-Activity Relationship | 1984 |
New folate analogs of the 10-deaza-aminopterin series. Further evidence for markedly increased antitumor efficacy compared with methotrexate in ascitic and solid murine tumor models.
Topics: Aminopterin; Animals; Drug Evaluation, Preclinical; Female; Methotrexate; Mice; Neoplasms, Experimental; Structure-Activity Relationship | 1984 |
A new analogue of 10-deazaaminopterin with markedly enhanced curative effects against human tumor xenografts in mice.
Topics: Aminopterin; Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Enzyme Inhibitors; Folic Acid Antagonists; Humans; Lung Neoplasms; Methotrexate; Mice; Mice, Nude; Structure-Activity Relationship; Substrate Specificity; Tetrahydrofolate Dehydrogenase; Tumor Cells, Cultured | 1998 |