ectoine has been researched along with pyrostatin a in 56 studies
| Studies (ectoine) | Trials (ectoine) | Recent Studies (post-2010) (ectoine) | Studies (pyrostatin a) | Trials (pyrostatin a) | Recent Studies (post-2010) (pyrostatin a) |
|---|---|---|---|---|---|
| 318 | 10 | 183 | 83 | 0 | 43 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (1.79) | 18.2507 |
| 2000's | 21 (37.50) | 29.6817 |
| 2010's | 30 (53.57) | 24.3611 |
| 2020's | 4 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Abdel-Aziz, H; Efferth, T; Khayyal, MT; Scherner, O; Wadie, W | 1 |
| Borges, N; Cánovas, D; Nieto, JJ; Santos, H; Vargas, C; Ventosa, A | 1 |
| Nagata, S; Wang, YB | 1 |
| Grammann, K; Kunte, HJ; Volke, A | 1 |
| Kunte, HJ; Vermeulen, V | 1 |
| Bernhard, M; Grammel, N; Keller, U; Prabhu, J; Schauwecker, F | 1 |
| Gambacorta, A; Motta, A; Romano, I | 1 |
| Bernard, T; Blanco, C; Bremer, E; Jebbar, M; Sohn-Bösser, L | 1 |
| Kanapathipillai, M; Lentzen, G; Park, CB; Sierks, M | 1 |
| Blanco, C; Calderón, MI; Carrasco, R; Iglesias-Guerra, F; Jebbar, M; Nieto, JJ; Vargas, C | 1 |
| Cánovas, D; Csonka, LN; García-Estepa, R; Iglesias-Guerra, F; Nieto, JJ; Vargas, C; Ventosa, A | 1 |
| Nagata, S; Wang, C; Zhu, D | 1 |
| Argandoña, M; Capote, N; García-Estepa, R; Iglesias-Guerra, F; Nieto, JJ; Reina-Bueno, M; Vargas, C | 1 |
| Galinski, EA; Gütschow, M; Kolp, S; Pietsch, M | 1 |
| Catapano, A; De Rosa, M; Galinski, EA; Maresca, C; Schiraldi, C | 1 |
| Castellanos, L; Duque, C; Espada, A; Jiménez, C; Rodríguez, J; Zea, S | 1 |
| Bremer, E; Bursy, J; Pica, N; Pierik, AJ | 1 |
| André, P; Cornacchione, S; de Quéral, D; Heusèle, C; Kurfurst, R; Lazou, K; Neveu, M; Perrier, E; Renimel, I; Sadick, NS; Schnebert, S; Talbourdet, S; Viron, C | 1 |
| Bremer, E; Hanekop, N; Höing, M; Jebbar, M; Schmitt, L; Sohn-Bösser, L | 1 |
| Bremer, E; Bursy, J; Hartmann, H; Jebbar, M; Kuhlmann, AU; Pierik, AJ; Pittelkow, M | 1 |
| Bönig, T; Bremer, E; Bursy, J; Lecher, J; Pittelkow, M; Schmitt, L; Smits, SH; Zobel, S | 1 |
| Appel, D; Lentzen, G | 1 |
| Alvarez, HM; Cesari, AC; Keller, U; Malkus, U; Maskow, T; Mayer, F; Peressutti, SR; Rasch, C; Reichelt, R; Silva, RA; Steinbüchel, A; Zamit, AL | 1 |
| Galla, HJ; Harishchandra, RK; Lentzen, G; Neuhaus, T; Wulff, S | 1 |
| Bremer, E; Bursy, J; Craan, T; Heine, A; Pittelkow, M; Reuter, K | 1 |
| Fallet, C; Franco-Lara, E; Rohe, P | 1 |
| Held, C; Neuhaus, T; Sadowski, G | 1 |
| Argandoña, M; Iglesias-Guerra, F; Jebbar, M; Nieto, JJ; Reina-Bueno, M; Rodríguez-Moya, J; Vargas, C | 1 |
| Bremer, E; Heider, J; Jensen, RA; Pittelkow, M; Sinner, T; Stöveken, N | 1 |
| Bremer, E; Bursy, J; Hoffmann, T; Jebbar, M; Kuhlmann, AU | 1 |
| Cao, Z; Dong, L; Fang, F; He, M; Li, W; Li, Y; Liang, Y; Tang, S; Wang, L | 1 |
| Galla, HJ; Harishchandra, RK; Kerth, A; Lentzen, G; Neuhaus, T; Sachan, AK | 1 |
| Galla, HJ; Harishchandra, RK; Heuer, A; Rubner, O; Smiatek, J | 1 |
| Cai, L; Gong, J; Grass, G; Hu, Y; Johnstone, L; Li, X; Rensing, C; Wang, G | 1 |
| Ablinger, E; Hellweger, M; Leitgeb, S; Zimmer, A | 1 |
| Gur, E; Meijler, M; Niederweis, M; Ofer, N; Speer, A; Wang, Y; Wishkautzan, M | 1 |
| Bremer, E; Buckel, W; Gohlke, H; Höppner, A; Mulnaes, D; Pittelkow, M; Smits, SH; Widderich, N | 1 |
| Avanti, C; Frijlink, HW; Hinrichs, WL; Saluja, V; van Streun, EL | 1 |
| Bremer, E; Heider, J; Höppner, A; Pittelkow, M; Smits, SH; Widderich, N | 1 |
| Amendt, B; Galinski, EA; Moritz, KD; Witt, EM | 1 |
| Argandoña, M; Bernal, V; Cánovas, M; Csonka, LN; Nieto, JJ; Pastor, JM; Salvador, M; Vargas, C | 1 |
| Cai, Z; Deng, W; He, J; Huang, W; Li, S; Lu, Y; Ren, S; Shao, Z; Wang, J; Zhao, G | 1 |
| Bremer, E; Czech, L; Dickschat, JS; Elling, FJ; Heider, J; Könneke, M; Pittelkow, M; Riclea, R; Stöveken, N; Widderich, N | 1 |
| Bashir, A; Bashir, S; Fazili, KM; Habib, M; Hazari, YM; Hilal, N; Irfan, S; Ul Haq, E | 1 |
| Gu, J; Li, H; Liu, Y; Tao, P; Yu, Y | 1 |
| Binzen, IM; Bremer, E; Heider, J; Hoffmann, T; Schulz, A; Stöveken, N | 1 |
| Bremer, E; Czech, L; Stöveken, N | 1 |
| Nafissi-Varcheh, N; Salmannejad, F | 1 |
| Bönig, T; Bremer, E; Dickschat, JS; Freibert, SA; Heider, J; Hermann, L; Hoffmann, T; Riclea, R; Schulz, A | 1 |
| Bremer, E; Czech, L | 1 |
| Castner, DG; Killian, MS; Taylor, AJ | 1 |
| Chang, YK; Chen, WC; Hsu, CC; Lan, JC; Wang, LF; Wei, YH | 1 |
| Altegoer, F; Bange, G; Bremer, E; Czech, L; Hermann, L; Mais, CN; Richter, AA; Seubert, A; Wernersbach, I | 1 |
| Chang, DP; Goode, M; Nayak, PK; Rajagopal, K | 1 |
| Dick, HB; Joachim, SC; Kuehn, S; Mueller-Buehl, AM; Satgunarajah, Y; Tsai, T | 1 |
| Jiang, M; Li, L; Liu, H; Liu, M; Shi, M; Zheng, Y | 1 |
1 review(s) available for ectoine and pyrostatin a
| Article | Year |
|---|---|
Microbial production of ectoine and hydroxyectoine as high-value chemicals.
Topics: Amino Acids, Diamino; Bacterial Proteins; Bioreactors; Biosynthetic Pathways; Fermentation; Halomonas; Osmotic Pressure; Salinity | 2021 |
55 other study(ies) available for ectoine and pyrostatin a
| Article | Year |
|---|---|
Bacteria-Derived Compatible Solutes Ectoine and 5α-Hydroxyectoine Act as Intestinal Barrier Stabilizers to Ameliorate Experimental Inflammatory Bowel Disease.
Topics: Amino Acids, Diamino; Animals; Bacteria; Colitis; Colon; Egypt; Glutathione; Humans; Inflammatory Bowel Diseases; Intercellular Adhesion Molecule-1; Interleukin-1beta; Intestines; Male; Molecular Structure; Peroxidase; Rats; Rats, Wistar; Solutions; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha | 2015 |
Role of Ngamma-acetyldiaminobutyrate as an enzyme stabilizer and an intermediate in the biosynthesis of hydroxyectoine.
Topics: Amino Acids, Diamino; Aminobutyrates; Animals; Enzyme Stability; Gammaproteobacteria; Hydro-Lyases; Magnetic Resonance Spectroscopy; Rabbits; Sodium Chloride; Temperature | 1999 |
Interrelation between synthesis and uptake of ectoine for the growth of the halotolerant Brevibacterium species JCM 6894 at high osmolarity.
Topics: Alanine; Amino Acids, Diamino; Betaine; Brevibacterium; Chromatography, High Pressure Liquid; Glutamic Acid; Magnetic Resonance Spectroscopy; Osmotic Pressure; Sodium Chloride | 2001 |
New type of osmoregulated solute transporter identified in halophilic members of the bacteria domain: TRAP transporter TeaABC mediates uptake of ectoine and hydroxyectoine in Halomonas elongata DSM 2581(T).
Topics: Acetyltransferases; Amino Acids, Diamino; Bacterial Proteins; Biological Transport; Culture Media; DNA Transposable Elements; Halomonas; Molecular Sequence Data; Mutagenesis, Insertional; Open Reading Frames; Osmotic Pressure; RNA-Binding Proteins; Sodium Chloride; Transcription Factors | 2002 |
Marinococcus halophilus DSM 20408T encodes two transporters for compatible solutes belonging to the betaine-carnitine-choline transporter family: identification and characterization of ectoine transporter EctM and glycine betaine transporter BetM.
Topics: Amino Acid Sequence; Amino Acids, Diamino; Bacterial Proteins; Betaine; Biological Transport, Active; Cloning, Molecular; DNA, Bacterial; Escherichia coli; Genes, Bacterial; Gram-Positive Bacteria; Kinetics; Membrane Transport Proteins; Molecular Sequence Data; Osmotic Pressure; Plasmids; Recombinant Proteins; Restriction Mapping; Sequence Homology, Amino Acid | 2004 |
Functional expression of the ectoine hydroxylase gene (thpD) from Streptomyces chrysomallus in Halomonas elongata.
Topics: Amino Acids, Diamino; Bacterial Proteins; Biotechnology; Gene Expression Regulation, Bacterial; Halomonas; Mixed Function Oxygenases; Molecular Sequence Data; Sequence Analysis, DNA; Streptomyces | 2004 |
Rapid and sensitive NMR method for osmolyte determination.
Topics: Amino Acids, Diamino; Betaine; Glutamic Acid; Halomonas; Hydrogen; Magnetic Resonance Spectroscopy; Microbiological Techniques; Osmosis; Sensitivity and Specificity; Sulfolobus; Trehalose | 2004 |
Ectoine-induced proteins in Sinorhizobium meliloti include an Ectoine ABC-type transporter involved in osmoprotection and ectoine catabolism.
Topics: Amino Acids, Diamino; ATP-Binding Cassette Transporters; Bacterial Proteins; Betaine; Electrophoresis, Gel, Two-Dimensional; Gene Expression Regulation, Bacterial; Genes, Bacterial; Multigene Family; Mutation; Operon; Plasmids; Proteome; Sinorhizobium meliloti; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Water-Electrolyte Balance | 2005 |
Ectoine and hydroxyectoine inhibit aggregation and neurotoxicity of Alzheimer's beta-amyloid.
Topics: Aged; Alzheimer Disease; Amino Acids, Diamino; Amyloid beta-Peptides; Cell Line, Tumor; Cell Survival; Humans; Microscopy, Atomic Force; Molecular Structure; Neuroblastoma; Peptide Fragments | 2005 |
Ectoines as compatible solutes and carbon and energy sources for the halophilic bacterium Chromohalobacter salexigens.
Topics: Amino Acids, Diamino; Betaine; Biological Transport; Carbon; Culture Media; Energy Intake; Glucose; Halomonadaceae; Osmosis; Sodium Chloride; Solutions | 2006 |
Osmoprotection of Salmonella enterica serovar Typhimurium by Ngamma-acetyldiaminobutyrate, the precursor of the compatible solute ectoine.
Topics: Amino Acids, Diamino; Aminobutyrates; Chromatography, High Pressure Liquid; Halomonadaceae; Heat-Shock Response; Hydro-Lyases; Magnetic Resonance Spectroscopy; Mutation; Osmolar Concentration; Salmonella typhimurium; Sodium Chloride; Symporters; Water-Electrolyte Balance | 2006 |
Supplementation effects of hydroxyectoine on proline uptake of downshocked Brevibacterium sp. JCM 6894.
Topics: Amino Acids, Diamino; Brevibacterium; Carbohydrates; Carbon; Cell Proliferation; Culture Media; Osmotic Pressure; Proline | 2006 |
The ectD gene, which is involved in the synthesis of the compatible solute hydroxyectoine, is essential for thermoprotection of the halophilic bacterium Chromohalobacter salexigens.
Topics: Adaptation, Physiological; Amino Acid Sequence; Amino Acids, Diamino; Chromosome Mapping; Conserved Sequence; DNA, Bacterial; Halomonadaceae; Hot Temperature; Hydro-Lyases; Kinetics; Molecular Sequence Data; Plasmids; Sequence Alignment; Sequence Homology; Sodium Chloride; Temperature | 2006 |
Compatible solutes as protectants for zymogens against proteolysis.
Topics: Amino Acids, Diamino; Animals; Betaine; Catalysis; Cattle; Chymotrypsinogen; Endopeptidases; Enteropeptidase; Enzyme Activation; Enzyme Precursors; Enzyme Stability; Molecular Structure; Swine; Trypsin; Trypsinogen | 2006 |
High-yield cultivation of Marinococcus M52 for production and recovery of hydroxyectoine.
Topics: Amino Acids, Diamino; Biomass; Bioreactors; Biotechnology; Filtration; Gram-Positive Cocci; Oxygen | 2006 |
Isolation and synthesis of (-)-(5S)-2-imino-1-methylpyrrolidine-5- carboxylic acid from Cliona tenuis: structure revision of pyrostatins.
Topics: Amino Acids, Diamino; Animals; Imines; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Porifera; Pyrrolidines; Stereoisomerism | 2006 |
Osmotically induced synthesis of the compatible solute hydroxyectoine is mediated by an evolutionarily conserved ectoine hydroxylase.
Topics: Amino Acid Motifs; Amino Acid Sequence; Amino Acids, Diamino; Bacillus; Bacterial Proteins; Carbon Isotopes; Chromatography, High Pressure Liquid; Conserved Sequence; Culture Media; Databases, Protein; Dose-Response Relationship, Drug; Escherichia coli; Evolution, Molecular; Genes, Bacterial; Mixed Function Oxygenases; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Osmosis; Sequence Homology, Amino Acid; Sodium Chloride; Solutions; Transcription, Genetic | 2007 |
In vivo skin antioxidant effect of a new combination based on a specific Vitis vinifera shoot extract and a biotechnological extract.
Topics: Adult; Amino Acids, Diamino; Antioxidants; Biotechnology; Cells, Cultured; Female; Humans; Keratinocytes; Middle Aged; Plant Extracts; Reactive Oxygen Species; Skin Aging; Vitis | 2007 |
Crystal structure of the ligand-binding protein EhuB from Sinorhizobium meliloti reveals substrate recognition of the compatible solutes ectoine and hydroxyectoine.
Topics: Amino Acids, Diamino; Bacterial Proteins; Binding Sites; Crystallography; Ligands; Mutagenesis, Site-Directed; Protein Binding; Protein Conformation; Sinorhizobium meliloti; Spectrometry, Fluorescence | 2007 |
Synthesis and uptake of the compatible solutes ectoine and 5-hydroxyectoine by Streptomyces coelicolor A3(2) in response to salt and heat stresses.
Topics: Amino Acids, Diamino; Bacterial Proteins; Carbon Radioisotopes; Hot Temperature; Hydrolases; Metabolic Networks and Pathways; Multigene Family; Salts; Streptomyces coelicolor | 2008 |
The crystal structure of UehA in complex with ectoine-A comparison with other TRAP-T binding proteins.
Topics: Amino Acids, Diamino; Bacterial Proteins; Binding Sites; Biological Transport; Crystallography, X-Ray; Genome, Bacterial; Halomonas; Kinetics; Ligands; Models, Molecular; Protein Binding; Protein Structure, Secondary; Rhodobacteraceae; Substrate Specificity | 2009 |
The pyrostatins A and B do not inhibit N-acetyl-beta-D-glucosaminidase.
Topics: Amino Acids, Diamino; Animals; beta-N-Acetylhexosaminidases; Cattle; Enzyme Activation; Imines; Kidney; Magnetic Resonance Spectroscopy; Molecular Structure; Pyrrolidines | 2009 |
Physiological and morphological responses of the soil bacterium Rhodococcus opacus strain PD630 to water stress.
Topics: Alkanes; Amino Acids, Diamino; Cell Wall; Dehydration; Energy Metabolism; Gluconates; Microbial Viability; Osmotic Pressure; Polysaccharides, Bacterial; Rhodococcus; Soil Microbiology; Stress, Physiological; Trehalose; Triglycerides | 2004 |
The effect of compatible solute ectoines on the structural organization of lipid monolayer and bilayer membranes.
Topics: Amino Acids, Diamino; Calorimetry, Differential Scanning; Lipid Bilayers; Lipids; Microscopy, Fluorescence; Temperature | 2010 |
Synthesis of 5-hydroxyectoine from ectoine: crystal structure of the non-heme iron(II) and 2-oxoglutarate-dependent dioxygenase EctD.
Topics: Amino Acid Motifs; Amino Acids; Amino Acids, Diamino; Bacillus; Bacterial Proteins; Binding Sites; Crystallography, X-Ray; Dioxygenases; Genome, Bacterial; Heme; Hydroxylation; Iron; Ketoglutaric Acids; Ligands; Models, Molecular; Pliability; Protein Structure, Secondary; Static Electricity | 2010 |
Process optimization of the integrated synthesis and secretion of ectoine and hydroxyectoine under hyper/hypo-osmotic stress.
Topics: Amino Acids, Diamino; Bioreactors; Cell Culture Techniques; Chromohalobacter; Osmotic Pressure; Systems Integration | 2010 |
Compatible solutes: Thermodynamic properties and biological impact of ectoines and prolines.
Topics: Amino Acids, Diamino; Osmotic Pressure; Proline; Salts; Solubility; Solutions; Temperature; Thermodynamics; Urea; Water | 2010 |
Involvement of EupR, a response regulator of the NarL/FixJ family, in the control of the uptake of the compatible solutes ectoines by the halophilic bacterium Chromohalobacter salexigens.
Topics: Amino Acids, Diamino; Bacterial Proteins; Biological Transport; Carbon; Chromohalobacter; DNA Transposable Elements; DNA, Bacterial; Frameshift Mutation; Gene Expression Regulation, Bacterial; Genes, Bacterial; Glucose; Membrane Transport Modulators; Membrane Transport Proteins; Mutagenesis, Insertional; Osmolar Concentration; Osmotic Pressure; Promoter Regions, Genetic; Salinity; Signal Transduction; Sodium Chloride | 2010 |
A specialized aspartokinase enhances the biosynthesis of the osmoprotectants ectoine and hydroxyectoine in Pseudomonas stutzeri A1501.
Topics: Amino Acids, Diamino; Aspartate Kinase; Aspartate-Semialdehyde Dehydrogenase; Aspartic Acid; Bacterial Proteins; Computational Biology; DNA, Bacterial; Escherichia coli; Gene Expression Regulation, Bacterial; Lysine; Multigene Family; Plasmids; Pseudomonas stutzeri; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Stress, Physiological; Threonine; Transcription, Genetic | 2011 |
Ectoine and hydroxyectoine as protectants against osmotic and cold stress: uptake through the SigB-controlled betaine-choline- carnitine transporter-type carrier EctT from Virgibacillus pantothenticus.
Topics: Amino Acids, Diamino; Bacterial Proteins; Blotting, Northern; Carbon Radioisotopes; Cold-Shock Response; DNA, Bacterial; Escherichia coli; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Genetic Complementation Test; Membrane Transport Proteins; Molecular Sequence Data; Osmotic Pressure; Sequence Analysis, DNA; Sigma Factor; Staining and Labeling; Stress, Physiological; Substrate Specificity; Transcription Initiation Site; Virgibacillus | 2011 |
[Cloning and characterization of gene cluster for biosynthesis of ectoine and 5-hydroxyectoine from extreme halotolerant actinomycete strain Prauserella alba YIM 90005(T)].
Topics: Actinomycetales; Acyltransferases; Amino Acid Sequence; Amino Acids, Diamino; Bacterial Proteins; Base Sequence; Cloning, Molecular; Gene Expression Regulation, Bacterial; Genes, Bacterial; Hydro-Lyases; Molecular Sequence Data; Multigene Family; Osmotic Pressure; Sequence Analysis, DNA; Sodium Chloride; Transaminases | 2011 |
Compatible solutes: ectoine and hydroxyectoine improve functional nanostructures in artificial lung surfactants.
Topics: Amino Acids, Diamino; Microscopy, Atomic Force; Nanostructures; Pulmonary Surfactants; Solubility | 2011 |
Properties of compatible solutes in aqueous solution.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Amino Acids, Diamino; Molecular Conformation; Molecular Dynamics Simulation; Solutions; Stereoisomerism; Urea; Water | 2012 |
Genome sequence of the moderately halotolerant, arsenite-oxidizing bacterium Pseudomonas stutzeri TS44.
Topics: Amino Acids, Diamino; Arsenites; DNA, Bacterial; Genome, Bacterial; Molecular Sequence Data; Oxidation-Reduction; Pseudomonas stutzeri; Sequence Analysis, DNA; Soil Microbiology; Soil Pollutants | 2012 |
Evaluating the effects of buffer conditions and extremolytes on thermostability of granulocyte colony-stimulating factor using high-throughput screening combined with design of experiments.
Topics: Amino Acids, Diamino; Buffers; Carbohydrates; Chemistry, Pharmaceutical; Drug Stability; Granulocyte Colony-Stimulating Factor; High-Throughput Screening Assays; Hot Temperature; Hydrogen-Ion Concentration | 2012 |
Ectoine biosynthesis in Mycobacterium smegmatis.
Topics: Amino Acids, Diamino; Mycobacterium smegmatis; Osmotic Pressure; Salinity; Water-Electrolyte Balance | 2012 |
Molecular dynamics simulations and structure-guided mutagenesis provide insight into the architecture of the catalytic core of the ectoine hydroxylase.
Topics: Amino Acids, Diamino; Catalytic Domain; Iron; Ketoglutaric Acids; Mixed Function Oxygenases; Molecular Dynamics Simulation; Mutagenesis, Site-Directed; Mutation; Protein Conformation | 2014 |
Stability of lysozyme in aqueous extremolyte solutions during heat shock and accelerated thermal conditions.
Topics: Amino Acids, Diamino; Betaine; Enzyme Stability; Glyceric Acids; Hot Temperature; Mannose; Muramidase; Protein Unfolding; Solutions; Trehalose | 2014 |
Biochemical properties of ectoine hydroxylases from extremophiles and their wider taxonomic distribution among microorganisms.
Topics: Amino Acids, Diamino; Bacteria; Bacterial Proteins; Enzyme Stability; Gene Expression Regulation, Bacterial; Genes, Bacterial; Kinetics; Mixed Function Oxygenases; Models, Molecular; Multigene Family; Phylogeny | 2014 |
The hydroxyectoine gene cluster of the non-halophilic acidophile Acidiphilium cryptum.
Topics: Acidiphilium; Alum Compounds; Amino Acids, Diamino; Computational Biology; Gene Expression Regulation, Bacterial; Genes, Bacterial; Genetic Vectors; Hydro-Lyases; Hydrogen-Ion Concentration; Isoelectric Point; Multigene Family; Osmotic Pressure; Sodium Chloride | 2015 |
Contribution of RpoS to metabolic efficiency and ectoines synthesis during the osmo- and heat-stress response in the halophilic bacterium Chromohalobacter salexigens.
Topics: Amino Acids, Diamino; Bacterial Proteins; Chromohalobacter; Gene Expression Regulation, Bacterial; Gene Knockout Techniques; Heat-Shock Response; Osmotic Pressure; Sigma Factor | 2015 |
GlnR-Mediated Regulation of ectABCD Transcription Expands the Role of the GlnR Regulon to Osmotic Stress Management.
Topics: Amino Acids, Diamino; Bacterial Proteins; Gene Expression Regulation, Bacterial; Glutamates; Mutation; Osmotic Pressure; Regulon; Streptomyces coelicolor; Trans-Activators; Transcription, Genetic | 2015 |
Strangers in the archaeal world: osmostress-responsive biosynthesis of ectoine and hydroxyectoine by the marine thaumarchaeon Nitrosopumilus maritimus.
Topics: Amino Acid Sequence; Amino Acids, Diamino; Archaea; Escherichia coli; Gene Transfer, Horizontal; Hydro-Lyases; Mechanoreceptors; Mixed Function Oxygenases; Multigene Family; Osmotic Pressure; Phylogeny | 2016 |
Natural osmolytes alleviate GRP78 and ATF-4 levels: Corroboration for potential modulators of unfolded protein response.
Topics: Activating Transcription Factor 4; Amino Acids, Diamino; Betaine; Biomarkers; Cell Survival; Dose-Response Relationship, Drug; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Heat-Shock Proteins; HEK293 Cells; Humans; Sarcosine; Tunicamycin; Unfolded Protein Response | 2016 |
Ectoine and 5-hydroxyectoine accumulation in the halophile Virgibacillus halodenitrificans PDB-F2 in response to salt stress.
Topics: Amino Acids, Diamino; Gene Expression Regulation, Bacterial; Osmotic Pressure; Salinity; Salt Tolerance; Sodium Chloride; Stress, Physiological; Virgibacillus | 2016 |
Feeding on compatible solutes: A substrate-induced pathway for uptake and catabolism of ectoines and its genetic control by EnuR.
Topics: Amino Acids, Diamino; Aspartic Acid; Bacterial Proteins; Carbon; Culture Media; Membrane Transport Proteins; Multigene Family; Nitrogen; Rhodobacteraceae; Transcription Factors | 2017 |
EctD-mediated biotransformation of the chemical chaperone ectoine into hydroxyectoine and its mechanosensitive channel-independent excretion.
Topics: Amino Acids, Diamino; Bacterial Proteins; Biological Transport; Biotransformation; Escherichia coli; Mixed Function Oxygenases; Molecular Chaperones; Pseudomonas stutzeri | 2016 |
Ectoine and hydroxyectoine inhibit thermal-induced aggregation and increase thermostability of recombinant human interferon Alfa2b.
Topics: Amino Acids, Diamino; Cell Line; Drug Stability; Hot Temperature; Humans; Interferon alpha-2; Interferon-alpha; Protein Aggregates; Protein Stability; Recombinant Proteins | 2017 |
Transcriptional regulation of ectoine catabolism in response to multiple metabolic and environmental cues.
Topics: Amino Acids, Diamino; Aminobutyrates; Bacterial Proteins; Biological Transport; Cues; DNA, Bacterial; Gene Expression Regulation, Bacterial; Multigene Family; Regulatory Elements, Transcriptional; Rhodobacteraceae; Trans-Activators | 2017 |
With a pinch of extra salt-Did predatory protists steal genes from their food?
Topics: Amino Acids, Diamino; Archaea; Bacteria; Bacterial Physiological Phenomena; Betaine; Biological Transport; Genes, Archaeal; Genes, Bacterial; Inositol; Introns; Models, Biological; Osmotic Pressure; Phylogeny; Salinity; Salt Stress; Transcription, Genetic | 2018 |
Stabilization of dry protein coatings with compatible solutes.
Topics: Amino Acids, Diamino; Colorimetry; Desiccation; Fluid Therapy; Horseradish Peroxidase; Immobilized Proteins; Protein Stability; Spectrometry, Mass, Secondary Ion; Titanium; Water | 2018 |
Exploring useful fermentation strategies for the production of hydroxyectoine with a halophilic strain, Halomonas salina BCRC 17875.
Topics: Amino Acids, Diamino; Bioreactors; Culture Media; Fermentation; Halomonas; Iron; Ketoglutaric Acids; Metabolic Engineering; Microbiological Techniques; Mixed Function Oxygenases; Salt Tolerance | 2019 |
Degradation of the microbial stress protectants and chemical chaperones ectoine and hydroxyectoine by a bacterial hydrolase-deacetylase complex.
Topics: Amino Acids, Diamino; Bacterial Proteins; Catalytic Domain; Gene Expression Regulation, Bacterial; Halomonas; Histone Deacetylases; Hydrolases; Molecular Chaperones; Multigene Family; Osmoregulation; Rhodobacteraceae | 2020 |
Ectoine and Hydroxyectoine Stabilize Antibodies in Spray-Dried Formulations at Elevated Temperature and during a Freeze/Thaw Process.
Topics: Amino Acids, Diamino; Antibodies; Chemistry, Pharmaceutical; Drug Stability; Excipients; Freeze Drying; Freezing; Protein Stability; Proteins; Temperature; Trehalose | 2020 |
Protective effect of the extremolytes ectoine and hydroxyectoine in a porcine organ culture.
Topics: Amino Acids, Diamino; Animals; Humans; Organ Culture Techniques; Retinal Ganglion Cells; Swine | 2020 |