ecteinascidin 743 has been researched along with pm 01183 in 10 studies
| Studies (ecteinascidin 743) | Trials (ecteinascidin 743) | Recent Studies (post-2010) (ecteinascidin 743) | Studies (pm 01183) | Trials (pm 01183) | Recent Studies (post-2010) (pm 01183) |
|---|---|---|---|---|---|
| 660 | 102 | 404 | 72 | 18 | 72 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 9 (90.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Escargueil, AE; Galmarini, CM; Henriques, JA; Larsen, AK; Machado, MS; Ouaret, D; Poindessous, V; Rocca, CJ; Sarasin, A; Soares, DG | 1 |
| Allavena, P; Bello, E; Cuevas, C; D'Incalci, M; Erba, E; Frapolli, R; Galmarini, CM; García-Fernández, LF; Porcu, L; Romano, M; Zangarini, M | 1 |
| Albella, B; Aracil, M; Bueren, JA; Gago, F; Galmarini, CM; Martínez, S; Pérez, L; Tercero, JC | 1 |
| Bouzid, H; Escargueil, AE; Galmarini, CM; Henriques, JA; Larsen, AK; Lima, M; Morel, C; Selle, F; Soares, DG | 1 |
| Allavena, P; Belgiovine, C; Bello, E; Beltrame, L; Craparotta, I; D'Incalci, M; Frapolli, R; Galmarini, CM; Liguori, M; Mannarino, L; Mantovani, A; Marchini, S; Paracchini, L | 1 |
| Caratti, G; Colmegna, B; D'Incalci, M; Erba, E; Ferrari, M; Fruscio, R; Gobbi, M; Lorusso, D; Matteo, C; Mezzanzanica, D; Panini, N; Perlangeli, MV; Porcu, L; Raspagliesi, F; Romano, M; Zucchetti, M | 1 |
| Aguilera, A; Barroso, S; Galmarini, CM; Herrera-Moyano, E; San Martín-Alonso, M; Tumini, E | 1 |
| He, W; Ma, D; Zhang, Z | 1 |
| Ballabio, S; Bello, E; Brich, S; Carrassa, L; Casali, PG; Craparotta, I; D'Incalci, M; Frapolli, R; Gatta, R; Gronchi, A; Mannarino, L; Marchini, S; Matteo, C; Pilotti, S; Sanfilippo, R | 1 |
| Alvarez-Lucena, C; Boscá, L; Cascante, M; Castrillo, A; de la Rosa Medina, JV; Fariñas, M; Fernández-Moreno, MA; Foguet, C; Landauro-Vera, R; Marin, S; Mas, F; Mojena, M; Povo-Retana, A; Sánchez-García, S | 1 |
10 other study(ies) available for ecteinascidin 743 and pm 01183
| Article | Year |
|---|---|
Trabectedin and its C subunit modified analogue PM01183 attenuate nucleotide excision repair and show activity toward platinum-resistant cells.
Topics: Antineoplastic Agents, Alkylating; Carbolines; Cell Line, Tumor; Chromatin; Cisplatin; Dioxoles; DNA Damage; DNA Repair; Drug Resistance, Neoplasm; Drug Synergism; HCT116 Cells; Heterocyclic Compounds, 4 or More Rings; HT29 Cells; Humans; Neoplasms; Organoplatinum Compounds; Oxaliplatin; Tetrahydroisoquinolines; Trabectedin; Ultraviolet Rays | 2011 |
Comparison of in vitro and in vivo biological effects of trabectedin, lurbinectedin (PM01183) and Zalypsis® (PM00104).
Topics: Alkaloids; Animals; Antineoplastic Agents, Alkylating; Apoptosis; Carbolines; Cell Cycle; Cell Proliferation; Cells, Cultured; Chickens; Dioxoles; DNA Damage; DNA Repair; Flow Cytometry; Heterocyclic Compounds, 4 or More Rings; Humans; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Nude; Molecular Structure; Neoplasms; Tetrahydroisoquinolines; Trabectedin; Xenograft Model Antitumor Assays | 2013 |
Inhibitory effects of marine-derived DNA-binding anti-tumour tetrahydroisoquinolines on the Fanconi anaemia pathway.
Topics: Animals; Antineoplastic Agents; Binding Sites; Carbolines; Cell Line, Tumor; Dioxoles; DNA; Dose-Response Relationship, Drug; Fanconi Anemia; Fanconi Anemia Complementation Group Proteins; Hematopoietic Stem Cells; Heterocyclic Compounds, 4 or More Rings; Humans; Mice; Mice, 129 Strain; Mice, Inbred BALB C; Mice, Transgenic; Mitomycin; Neoplasms; Signal Transduction; Tetrahydroisoquinolines; Trabectedin | 2013 |
Dual inhibition of ATR and ATM potentiates the activity of trabectedin and lurbinectedin by perturbing the DNA damage response and homologous recombination repair.
Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Ataxia Telangiectasia Mutated Proteins; Carbolines; Dioxoles; DNA Damage; HeLa Cells; Heterocyclic Compounds, 4 or More Rings; Humans; Recombinational DNA Repair; Tetrahydroisoquinolines; Trabectedin | 2016 |
Lurbinectedin reduces tumour-associated macrophages and the inflammatory tumour microenvironment in preclinical models.
Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Carbolines; Caspase 8; Cell Adhesion; Cell Movement; Chemokine CCL2; Dioxoles; Down-Regulation; Female; Fibrosarcoma; Gene Expression; Gene Expression Profiling; Heterocyclic Compounds, 4 or More Rings; HL-60 Cells; Humans; Interleukin-8; Leukocyte Count; Macrophages; Mice; Mice, Inbred C57BL; Monocytes; Neovascularization, Pathologic; Ovarian Neoplasms; rho GTP-Binding Proteins; Tetrahydroisoquinolines; Trabectedin; Tumor Microenvironment; U937 Cells; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays | 2017 |
Ascites interferes with the activity of lurbinectedin and trabectedin: Potential role of their binding to alpha 1-acid glycoprotein.
Topics: Animals; Antineoplastic Agents, Alkylating; Ascites; Carbolines; Cell Line, Tumor; Dioxoles; Dose-Response Relationship, Drug; Female; Heterocyclic Compounds, 4 or More Rings; Humans; Mice; Mice, Nude; Orosomucoid; Ovarian Neoplasms; Protein Binding; Tetrahydroisoquinolines; Trabectedin; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2017 |
The Antitumor Drugs Trabectedin and Lurbinectedin Induce Transcription-Dependent Replication Stress and Genome Instability.
Topics: Carbolines; Cell Proliferation; DNA Replication; Genomic Instability; HeLa Cells; Heterocyclic Compounds, 4 or More Rings; Humans; Trabectedin | 2019 |
A Scalable Total Synthesis of the Antitumor Agents Et-743 and Lurbinectedin.
Topics: Antineoplastic Agents; Carbolines; Heterocyclic Compounds, 4 or More Rings; Stereoisomerism; Trabectedin; Tyrosine | 2019 |
Establishment and characterisation of a new patient-derived model of myxoid liposarcoma with acquired resistance to trabectedin.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carbolines; Carrier Proteins; Cell Proliferation; Doxorubicin; Drug Resistance, Neoplasm; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Heterocyclic Compounds, 4 or More Rings; Humans; Liposarcoma, Myxoid; Mice; Mice, Nude; Trabectedin; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2019 |
Immunometabolic actions of trabectedin and lurbinectedin on human macrophages: relevance for their anti-tumor activity.
Topics: Humans; Lactic Acid; Macrophages; Neoplasms; Trabectedin; Tumor Microenvironment | 2023 |