ecteinascidin 743 has been researched along with ly335979 in 1 studies
| Studies (ecteinascidin 743) | Trials (ecteinascidin 743) | Recent Studies (post-2010) (ecteinascidin 743) | Studies (ly335979) | Trials (ly335979) | Recent Studies (post-2010) (ly335979) |
|---|---|---|---|---|---|
| 660 | 102 | 404 | 112 | 12 | 54 |
| Protein | Taxonomy | ecteinascidin 743 (IC50) | ly335979 (IC50) |
|---|---|---|---|
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | 0.0589 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Beijnen, JH; Beumer, JH; Buckle, T; Franke, NE; Lopez-Lazaro, L; Ouwehand, M; Schellens, JH; van Tellingen, O | 1 |
1 other study(ies) available for ecteinascidin 743 and ly335979
| Article | Year |
|---|---|
Trabectedin (ET-743, Yondelis) is a substrate for P-glycoprotein, but only high expression of P-glycoprotein confers the multidrug resistance phenotype.
Topics: Animals; Antineoplastic Agents, Alkylating; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Carbon Radioisotopes; Cell Line; Cell Membrane Permeability; Cell Survival; Dibenzocycloheptenes; Dioxoles; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Inhibitory Concentration 50; Intracellular Fluid; LLC-PK1 Cells; Membrane Transport Proteins; Mice; Paclitaxel; Quinolines; Swine; Tetrahydroisoquinolines; Trabectedin; Transfection | 2007 |