Page last updated: 2024-09-02

ecteinascidin 743 and indazoles

ecteinascidin 743 has been researched along with indazoles in 14 studies

Compound Research Comparison

Studies
(ecteinascidin 743)
Trials
(ecteinascidin 743)
Recent Studies (post-2010)
(ecteinascidin 743)
Studies
(indazoles)
Trials
(indazoles)
Recent Studies (post-2010) (indazoles)
6601024045,6095503,265

Protein Interaction Comparison

ProteinTaxonomyecteinascidin 743 (IC50)indazoles (IC50)
Chain A, Cell Division Protein Kinase 2Homo sapiens (human)185
Chain A, CELL DIVISION PROTEIN KINASE 2Homo sapiens (human)185
Chain A, Cell Division Protein Kinase 2Homo sapiens (human)185
Chain A, CELL DIVISION PROTEIN KINASE 2Homo sapiens (human)185
Chain A, CELL DIVISION PROTEIN KINASE 2Homo sapiens (human)185
Chain A, CELL DIVISION PROTEIN KINASE 2Homo sapiens (human)185
Chain A, CELL DIVISION PROTEIN KINASE 2Homo sapiens (human)185
Chain A, CELL DIVISION PROTEIN KINASE 2Homo sapiens (human)185
Chain A, CELL DIVISION PROTEIN KINASE 2Homo sapiens (human)185
Chain A, CELL DIVISION PROTEIN KINASE 2Homo sapiens (human)185
Chain A, CELL DIVISION PROTEIN KINASE 2Homo sapiens (human)185
Chain A, CELL DIVISION PROTEIN KINASE 2Homo sapiens (human)185
Chain A, CELL DIVISION PROTEIN KINASE 2Homo sapiens (human)185
Chain A, Cell Division Protein Kinase 2Homo sapiens (human)185

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's12 (85.71)24.3611
2020's2 (14.29)2.80

Authors

AuthorsStudies
Manson, SC; Penel, N; Powell, S; Sharma, S; Takyar, S1
Cornillie, J; Hompes, D; Li, H; Schöffski, P; Wozniak, A1
Cuesta, M; Guix, M; Hernández-Pastor, LJ; Lavernia, J; Villa, G1
Carbini, M; Maki, RG; Pang, A1
Azvolinsky, A1
Fader, AN; Ricci, S; Stone, RL1
Araki, N; Kawai, A; Takahashi, S; Ueda, T; Yonemori, K1
Blay, JY; Boye, K; Brahmi, M; Casali, PG; Duffaud, F; Fedenko, A; Gelderblom, H; Hindi, N; Italiano, A; Kawai, A; Kobayashi, E; Kosela, H; Le Cesne, A; Maki, RG; Martin-Broto, J; Mir, O; Patel, S; Provenzano, S; Rutkowski, P; Somaiah, N; Stacchiotti, S; Sundby Hall, K; Vincenzi, B1
Sleijfer, S; Vos, M1
Desar, IME; Fleuren, EDG; van der Graaf, WTA1
Hayashi, K; Igarashi, K; Miwa, S; Takeuchi, A; Tsuchiya, H; Yamamoto, N1
Blay, JY1
Asanuma, K; Hagi, T; Nakamura, T; Sudo, A1
Caldari, E; De Paolis, M; Fiore, M; Giannini, C; Pirini, MG; Sambri, A; Spinnato, P; Zucchini, R1

Reviews

9 review(s) available for ecteinascidin 743 and indazoles

ArticleYear
Efficacy and safety of pharmacological interventions in second- or later-line treatment of patients with advanced soft tissue sarcoma: a systematic review.
    BMC cancer, 2013, Aug-13, Volume: 13

    Topics: Antineoplastic Agents; Dacarbazine; Deoxycytidine; Dioxoles; Gemcitabine; Humans; Indazoles; Pyrimidines; Randomized Controlled Trials as Topic; Sarcoma; Sulfonamides; Tetrahydroisoquinolines; Trabectedin; Treatment Failure

2013
Soft tissue sarcoma: an update on systemic treatment options for patients with advanced disease.
    Oncology research and treatment, 2014, Volume: 37, Issue:6

    Topics: Antineoplastic Agents; Dioxoles; Doxorubicin; Evidence-Based Medicine; Humans; Ifosfamide; Indazoles; Pyrimidines; Sarcoma; Sulfonamides; Tetrahydroisoquinolines; Trabectedin; Treatment Outcome

2014
Contemporary Therapy for Advanced Soft-Tissue Sarcomas in Adults: A Review.
    JAMA oncology, 2016, Jul-01, Volume: 2, Issue:7

    Topics: Adult; Antineoplastic Agents; Dioxoles; Furans; Humans; Indazoles; Ketones; Pyrimidines; Randomized Controlled Trials as Topic; Sarcoma; Sulfonamides; Tetrahydroisoquinolines; Trabectedin; Tumor Microenvironment

2016
Uterine leiomyosarcoma: Epidemiology, contemporary treatment strategies and the impact of uterine morcellation.
    Gynecologic oncology, 2017, Volume: 145, Issue:1

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Chemotherapy, Adjuvant; Deoxycytidine; Diagnostic Errors; Dioxoles; Docetaxel; Doxorubicin; Female; Gemcitabine; Humans; Hysterectomy; Indazoles; Laparoscopy; Leiomyoma; Leiomyosarcoma; Morcellation; Neoplasm Staging; Pyrimidines; Sulfonamides; Taxoids; Tetrahydroisoquinolines; Trabectedin; Uterine Myomectomy; Uterine Neoplasms

2017
Systemic Therapy for Soft Tissue Sarcoma: Proposals for the Optimal Use of Pazopanib, Trabectedin, and Eribulin.
    Advances in therapy, 2017, Volume: 34, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Dioxoles; Furans; Humans; Indazoles; Japan; Ketones; Pyrimidines; Sarcoma; Sulfonamides; Tetrahydroisoquinolines; Trabectedin

2017
EJC's biennial report on metastatic soft tissue sarcoma: State of the art and future perspectives.
    European journal of cancer (Oxford, England : 1990), 2018, Volume: 88

    Topics: Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Dioxoles; Doxorubicin; Drug Therapy; Forecasting; Humans; Indazoles; Neoplasm Metastasis; Pyrimidines; Sarcoma; Sulfonamides; Tetrahydroisoquinolines; Trabectedin

2018
Systemic Treatment for Adults with Synovial Sarcoma.
    Current treatment options in oncology, 2018, 03-07, Volume: 19, Issue:2

    Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Humans; Ifosfamide; Indazoles; Pyrimidines; Sarcoma, Synovial; Sulfonamides; Trabectedin

2018
Therapeutic Targets for Bone and Soft-Tissue Sarcomas.
    International journal of molecular sciences, 2019, Jan-04, Volume: 20, Issue:1

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bone Neoplasms; Drug Therapy; Furans; Humans; Immunotherapy, Adoptive; Indazoles; Ipilimumab; Ketones; Nivolumab; Osteosarcoma; Progression-Free Survival; Pyrimidines; Sarcoma; Soft Tissue Neoplasms; Sorafenib; Sulfonamides; Trabectedin

2019
The Biology of Synovial Sarcoma: State-of-the-Art and Future Perspectives.
    Current treatment options in oncology, 2021, 10-23, Volume: 22, Issue:12

    Topics: Anthracyclines; Antineoplastic Agents; Chemotherapy, Adjuvant; Epigenomics; Gene Expression Regulation, Neoplastic; Genomics; Humans; Ifosfamide; Indazoles; Molecular Targeted Therapy; Pyrimidines; Radiotherapy, Adjuvant; Sarcoma, Synovial; Soft Tissue Neoplasms; Sulfonamides; Surgical Procedures, Operative; Trabectedin

2021

Other Studies

5 other study(ies) available for ecteinascidin 743 and indazoles

ArticleYear
Cost-effectiveness analysis of pazopanib in second-line treatment of advanced soft tissue sarcoma in Spain.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2015, Volume: 17, Issue:1

    Topics: Antineoplastic Agents; Clinical Trials, Phase III as Topic; Cost-Benefit Analysis; Dioxoles; Disease Progression; Drug Costs; Humans; Indazoles; Probability; Pyrimidines; Quality-Adjusted Life Years; Sarcoma; Spain; Sulfonamides; Tetrahydroisoquinolines; Trabectedin; Treatment Outcome

2015
Heterogeneous and Rare: Toward Histology-Specific Treatment of Soft-Tissue Sarcoma.
    Journal of the National Cancer Institute, 2016, Volume: 108, Issue:6

    Topics: Antineoplastic Agents; Chromosomal Proteins, Non-Histone; Dioxoles; Disease-Free Survival; DNA-Binding Proteins; Furans; Humans; Indazoles; Ketones; Molecular Targeted Therapy; Mutation; Pyrimidines; Sarcoma; SMARCB1 Protein; Sulfonamides; Tetrahydroisoquinolines; Trabectedin; Transcription Factors

2016
Activity of Pazopanib and Trabectedin in Advanced Alveolar Soft Part Sarcoma.
    The oncologist, 2018, Volume: 23, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Female; Follow-Up Studies; Humans; Indazoles; Male; Middle Aged; Prognosis; Pyrimidines; Retrospective Studies; Sarcoma, Alveolar Soft Part; Sulfonamides; Survival Rate; Trabectedin

2018
Treatment of advanced soft tissue sarcoma by histological subtype: wish, prediction or reality?
    Future oncology (London, England), 2019, Volume: 15, Issue:26s

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Deoxycytidine; Doxorubicin; Female; Furans; Gemcitabine; Humans; Ifosfamide; Indazoles; Ketones; Liposarcoma; Middle Aged; Prognosis; Pyrimidines; Sulfonamides; Survival Rate; Trabectedin

2019
Clinical Outcome of Systemic Treatment for Advanced Soft Tissue Sarcoma: Real-Life Perspective in Japan.
    Drug design, development and therapy, 2020, Volume: 14

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Anthracyclines; Antineoplastic Agents; Female; Furans; Humans; Indazoles; Japan; Kaplan-Meier Estimate; Ketones; Male; Middle Aged; Neoplasm Metastasis; Prognosis; Pyrimidines; Retrospective Studies; Sarcoma; Soft Tissue Neoplasms; Sulfonamides; Survival Analysis; Trabectedin; Treatment Outcome

2020