ecteinascidin 743 has been researched along with guanine in 3 studies
| Studies (ecteinascidin 743) | Trials (ecteinascidin 743) | Recent Studies (post-2010) (ecteinascidin 743) | Studies (guanine) | Trials (guanine) | Recent Studies (post-2010) (guanine) |
|---|---|---|---|---|---|
| 660 | 102 | 404 | 16,278 | 822 | 4,809 |
| Protein | Taxonomy | ecteinascidin 743 (IC50) | guanine (IC50) |
|---|---|---|---|
| Purine nucleoside phosphorylase | Homo sapiens (human) | 5 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Bailly, C; Kohlhagen, G; Kohn, KW; Mazumder, A; Pommier, Y; Waring, M | 1 |
| Dean-Colomb, W; Esteva, FJ | 1 |
| Gago, F; Mills, A | 1 |
1 review(s) available for ecteinascidin 743 and guanine
| Article | Year |
|---|---|
Emerging agents in the treatment of anthracycline- and taxane-refractory metastatic breast cancer.
Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Camptothecin; Clinical Trials as Topic; Deoxycytidine; Dioxoles; Diphtheria Toxin; Drug Resistance, Neoplasm; Drugs, Investigational; Epothilones; Female; Furans; Gemcitabine; Glutamates; Guanine; Humans; Interleukin-2; Ketones; Lapatinib; Neoplasm Metastasis; Organoplatinum Compounds; Oxaliplatin; Pemetrexed; Quinazolines; Recombinant Fusion Proteins; Tetrahydroisoquinolines; Trabectedin; Vinblastine; Vinorelbine | 2008 |
2 other study(ies) available for ecteinascidin 743 and guanine
| Article | Year |
|---|---|
DNA sequence- and structure-selective alkylation of guanine N2 in the DNA minor groove by ecteinascidin 743, a potent antitumor compound from the Caribbean tunicate Ecteinascidia turbinata.
Topics: Alkylation; Animals; Anthramycin; Antineoplastic Agents, Alkylating; Base Sequence; Binding Sites; Dioxoles; DNA; DNA Footprinting; Guanine; Isoquinolines; Molecular Sequence Data; Molecular Structure; Tetrahydroisoquinolines; Trabectedin; Urochordata | 1996 |
Insight into the sequence-specific elements leading to increased DNA bending and ligase-mediated circularization propensity by antitumor trabectedin.
Topics: Antineoplastic Agents; Base Sequence; DNA; Guanine; Humans; Ligases; Molecular Dynamics Simulation; Nucleic Acid Conformation; Protein Binding; RNA Polymerase II; Trabectedin | 2021 |