ecteinascidin 743 has been researched along with etoposide in 5 studies
| Studies (ecteinascidin 743) | Trials (ecteinascidin 743) | Recent Studies (post-2010) (ecteinascidin 743) | Studies (etoposide) | Trials (etoposide) | Recent Studies (post-2010) (etoposide) |
|---|---|---|---|---|---|
| 660 | 102 | 404 | 18,306 | 3,693 | 4,900 |
| Protein | Taxonomy | ecteinascidin 743 (IC50) | etoposide (IC50) |
|---|---|---|---|
| nuclear receptor coactivator 1 isoform 1 [Homo sapiens] | Homo sapiens (human) | 1.153 | |
| nuclear receptor coactivator 3 isoform a | Homo sapiens (human) | 1.4284 | |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Oryctolagus cuniculus (rabbit) | 3.187 | |
| Caspase-3 | Homo sapiens (human) | 1 | |
| DNA topoisomerase 2-beta | Homo sapiens (human) | 0.4299 | |
| Solute carrier organic anion transporter family member 1B3 | Homo sapiens (human) | 4.18 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Corey, EJ; Martinez, EJ; Owa, T; Schreiber, SL | 1 |
| Bertino, JR; Cordon-Cardo, C; Elisseyeff, Y; Faircloth, G; Jhanwar, S; Jimeno, J; Li, WW; Takahashi, N | 1 |
| Douer, D; Liu, SV; Tahbaz, A; Zneimer, S | 1 |
5 other study(ies) available for ecteinascidin 743 and etoposide
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Phthalascidin, a synthetic antitumor agent with potency and mode of action comparable to ecteinascidin 743.
Topics: Antineoplastic Agents, Alkylating; Bleomycin; Camptothecin; Cell Division; Cisplatin; Cross-Linking Reagents; Dioxoles; DNA Topoisomerases, Type I; DNA, Neoplasm; Doxorubicin; Etoposide; Female; Humans; Isoquinolines; Male; Mitomycin; Models, Molecular; Molecular Structure; Neoplasm Proteins; Paclitaxel; Phthalimides; Structure-Activity Relationship; Tetrahydroisoquinolines; Trabectedin; Tumor Cells, Cultured | 1999 |
Sensitivity of soft tissue sarcoma cell lines to chemotherapeutic agents: identification of ecteinascidin-743 as a potent cytotoxic agent.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Cell Cycle; Cell Survival; Dioxoles; Dose-Response Relationship, Drug; Doxorubicin; Etoposide; Humans; Inhibitory Concentration 50; Isoquinolines; Methotrexate; Proto-Oncogene Proteins c-bcl-2; Retinoblastoma Protein; Sarcoma; Sensitivity and Specificity; Tetrahydroisoquinolines; Trabectedin; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2001 |
Therapy-related acute myeloid leukemia following treatment with trabectedin for Ewing's sarcoma.
Topics: Adult; Antineoplastic Agents, Alkylating; Bone Neoplasms; Dioxoles; Etoposide; Fatal Outcome; Female; Gene Deletion; Gene Rearrangement; Humans; Leukemia, Myeloid, Acute; Myeloid-Lymphoid Leukemia Protein; Neoplasms, Second Primary; Sarcoma, Ewing; Tetrahydroisoquinolines; Topoisomerase Inhibitors; Trabectedin; Young Adult | 2011 |