econazole has been researched along with miconazole in 144 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 49 (34.03) | 18.7374 |
| 1990's | 39 (27.08) | 18.2507 |
| 2000's | 29 (20.14) | 29.6817 |
| 2010's | 24 (16.67) | 24.3611 |
| 2020's | 3 (2.08) | 2.80 |
| Authors | Studies |
|---|---|
| Kawamura, Y; Kida, S; Matsumoto, H; Ogata, M; Shimizu, S; Tawara, K | 1 |
| Brodie, AM; Clement, OO; Freeman, CM; Handratta, VD; Hartmann, RW; Njar, VC; Vasaitis, TS | 1 |
| Doman, TN; McGovern, SL; Seidler, J; Shoichet, BK | 1 |
| Artico, M; D'Auria, FD; De Martino, G; Di Pasquali, A; La Regina, G; Nencioni, L; Palamara, AT; Silvestri, R | 1 |
| Brien, JF; Dercho, RA; Kinobe, RT; Nakatsu, K; Szarek, WA; Vlahakis, JZ | 1 |
| Ekins, S; Harwood, HJ; Hoover, DJ; Lawton, MP; Mankowski, DC; Treadway, JL | 1 |
| Artico, M; Botta, M; Caporuscio, F; Cirilli, R; D'Auria, FD; De Melo, NR; Kelly, SL; La Regina, G; La Torre, F; Lamb, DC; Nencioni, L; Olla, S; Palamara, AT; Piscitelli, F; Silvestri, R; Tafi, A | 1 |
| Kelly, DE; Kelly, SL; Manning, NJ; Merkamm, M; Parker, JE; Pompon, D | 1 |
| Bergès, T; Bouchara, JP; Chabasse, D; Ernoult, E; Larcher, G; Tronchin, G; Vandeputte, P | 1 |
| Jackson, CJ; Kelly, DE; Kelly, SL; Lamb, DC; Marczylo, TH; Parker, JE; Warrilow, AG | 1 |
| Pratim Roy, P; Roy, K | 1 |
| Bergès, T; Bouchara, JP; Chabasse, D; Renier, G; Rocher, F; Tronchin, G; Vandeputte, P | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| DeGraw, AJ; Distefano, MD; Keiser, MJ; Ochocki, JD; Shoichet, BK | 1 |
| Driscoll, MD; Lafite, P; Levy, C; Leys, D; Mast, N; McLean, KJ; Munro, AW; Pikuleva, IA; Rigby, SE | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Bakmiwewa, SM; Ball, HJ; Fatokun, AA; Hunt, NH; Payne, RJ; Tran, A | 1 |
| Bron, S; Chambon, M; Colau, D; Majjigapu, SR; Michielin, O; Pilotte, L; Röhrig, UF; Turcatti, G; Van den Eynde, BJ; Vogel, P; Zoete, V | 1 |
| Balogh, I; Kim, HY; Koczok, K; Korade, Z; Liu, W; Mirnics, K; Porter, NA; Tallman, KA; Xu, L | 1 |
| Abell, C; Chan, DS; Coyne, AG; de Carvalho, LP; Hudson, SA; James, GG; Kavanagh, ME; Levy, CW; Leys, D; Marino, LB; McLean, KJ; Munro, AW; Surade, S | 1 |
| Azimi, I; Denny, WA; Flanagan, JU; Inserra, M; Monteith, GR; Stevenson, RJ; Vetter, I | 1 |
| Bian, Y; Chen, Y; Feng, F; He, SY; Jiang, X; Li, Q; Lin, H; Lu, X; Qu, W; Sun, H; Yang, H; Zhou, Y | 1 |
| Sun, B; Sun, N; Sun, Y; Tian, L; Zhao, D; Zhao, L; Zhao, S | 1 |
| Bernander, S; Faergemann, J | 1 |
| Drouhet, E | 1 |
| Negroni, R | 1 |
| Dupont, B; Lapresle, C | 1 |
| Plempel, M | 1 |
| François, J; Rijsselaere, M | 1 |
| Levine, HB | 1 |
| Fonteriz, R; García, AG; García-Sancho, J; López, MG; Villalobos, C | 1 |
| Clarkson, WD; Heemskerk, JW; Sage, SO; Sargeant, P | 1 |
| Hernández Molina, JM; Llosá, J; Martinez Brocal, A; Ventosa, A | 1 |
| Mahaut-Smith, MP; Merritt, JE; Rink, TJ; Sage, SO; Sargeant, P | 1 |
| Pearson, A; Salole, EG | 1 |
| Van Cutsem, J | 1 |
| D'Auria, FD; Simonetti, N; Strippqli, V | 1 |
| Guryn, R; Kotełko, B; Mikołajewska, H | 1 |
| Carlone, NA; Cuffini, AM; Tullio, V | 1 |
| Colli, E; Finzi, A; Pigatto, P; Scatigna, M | 1 |
| Cavrini, V; Di Pietra, AM; Gatti, R | 1 |
| Armelles, M | 1 |
| Abarca, L; Bragulat, M; Bruguera, T; Cabañes, FJ | 1 |
| Frosch, PJ; Raulin, C | 1 |
| Hopwood, V; Johnson, EM; Kennedy, CT; Smith, KJ; Van Cutsem, J; Vanden Bossche, H; Warnock, DW | 1 |
| Bastide, JM; Bastide, M; Jouvert, S; Lebecq, JC; Mallie, M; Montes, B | 1 |
| Kalter, DC; McBride, ME; Wolf, JE | 1 |
| Bossano, A; Cervetti, O; Forte, M; Pezzarossa, E | 1 |
| Bothe, C; Reinel, D; Riemann, U; Senff, H | 1 |
| Dix, BA; Freudenberger, J; Funke, PT; Georgopapadakou, NH; Smith, SA | 1 |
| Gugnani, HC; Okeke, CN | 1 |
| Bassiouny, A; Hindawy, DS; Kamel, T; Moawad, MK | 1 |
| De Bernardis, F; Lorenzini, R; Mercantini, R | 1 |
| Davies, RR; Zaini, F | 1 |
| Cohen, L | 1 |
| Bradbeer, CS; Thin, RN | 1 |
| Abbott, AB; Odds, FC; Webster, CE | 1 |
| Döring, HF; Ilgner, M | 1 |
| Docampo, R; Gonzalez-Cappa, SM; Katzin, AM; Moreno, SN; Stoppani, AO; Turrens, JF | 1 |
| Awouters, F; Janssen, PA; Levron, JC; Niemegeers, CJ | 1 |
| Bastide, JM; Bastide, M; Jouvert, S | 2 |
| Qadripur, SA | 1 |
| Ditrich, O; Otcenásek, M | 1 |
| Gorman, SP; Scott, EM; Wright, LR | 1 |
| Head, WS; O'Day, DM; Ray, WA; Robinson, RD | 1 |
| van der Stel, JJ; Voogd, CE | 1 |
| Harada, S; Kusunoki, T | 2 |
| Kawai, K; Nozawa, Y; Shiojiri, H; Watanabe, R | 1 |
| Henderson, JT; Jevons, S; O'Neill East, M | 1 |
| Dennerstein, GJ; Langley, R | 1 |
| Obolensky, W; Simon, U | 1 |
| Haass, R; Werk, R | 1 |
| Clayton, YM; Oji, EO | 1 |
| Georgopoulos, A; Mieth, H; Petranyi, G | 1 |
| Quiñones, CA | 1 |
| Bergan, T | 1 |
| Meyer-Rohn, J; Puschmann, M | 1 |
| Cazaux, M; Lepargneur, JP; Linas, MD; Riser, A; Saveres, C; Seguela, JP | 1 |
| Mücke, C | 1 |
| Bogle, RG; Johnstone, AP; Soo, SC; Vallance, P; Whitley, GS | 1 |
| Farndale, RW; Sage, SO; Sargeant, P | 1 |
| Aguirre, A; Goday, JJ; Ilardia, R; Soloeta, R; Yanguas, I | 1 |
| Brasini, S; De Luca, C; Fabbri, AA; Fanelli, C; Passi, S | 1 |
| Berry, M; Easty, DL; Gurung, A | 1 |
| Li, HX; Liao, YW | 1 |
| Hymel, LJ; Mason, MJ; Mayer, B | 1 |
| Ilavarasi, S; Ramakrishna, ES; Venugopal, PV; Venugopal, TV | 1 |
| Hegemann, L; Lahijani, KI; Toso, SM; Uitto, J; Webster, GF | 1 |
| Aussel, C; Breittmayer, JP | 1 |
| Friedman, FK; Hornstein, EH; Thomas, DE; Tsokos, GC; Vassilopoulos, D | 1 |
| Andrisano, V; Cavrini, V; Di Pietra, AM; Gotti, R | 1 |
| Graier, WF; Kostner, GM; Kukovetz, WR; Simecek, S | 1 |
| Adeyemi-Doro, FA; Chan, RC; Cheng, AF; Cheung, SW; Ng, TK | 1 |
| Williams, DC; Zisterer, DM | 1 |
| Kankaanranta, H; Li, L; Paakkari, I; Vaali, K; Vapaatalo, H | 1 |
| Blanco, JL; Garcia, ME; Guedeja-Marron, J | 1 |
| He, Y; Sun, B; Wang, Y | 1 |
| Benkó, I; Hernádi, F; Kovács, P; Megyeri, A | 1 |
| Helmeste, DM; Tang, SW; Vu, R | 1 |
| García, AG; García-Palomero, E; Herrero, CJ; Lomax, RB; Montiel, C | 1 |
| Venugopal, PV; Venugopal, TV | 1 |
| Daza, RM; Martín, JE; Martín, P; Martínez, MM; Mendaza, P; Portero, F; Sánchez, G | 1 |
| Benita, S; Korner, D; Piemi, MP | 1 |
| Jacobsen, J; Pedersen, M; Sørensen, AM | 1 |
| Benko, I; Hernádi, F; Kiss, A; Kovács, P; Kraicsovits, F; Megyeri, A; Somogyi, G; Tegyey, Z | 1 |
| Bouchara, JP; Chabasse, D; Declerk, P; Defontaine, A; Hallet, JN; Planchenault, C | 1 |
| Aikawa, K; Arai, H; Fujimoto, Y; Furuchi, T; Ikemoto, M; Inoue, K; Sato, Y | 1 |
| Bjerregaard, S; Jacobsen, J; Pedersen, M | 1 |
| Carson, CF; Hammer, KA; Riley, TV | 1 |
| Fowler, SM; Friedberg, T; Pritchard, MP; Riley, RJ; Sutcliffe, MJ; Wolf, CR | 1 |
| Jackson, CJ; Kelly, DE; Kelly, SL; Lamb, DC | 1 |
| Kuratko, CN; Stocco, DM; Walsh, LP | 1 |
| Charvalos, E; Tsatsakis, AM; Tzatzarakis, MN; Vakalounakis, D | 1 |
| Aboul-Enein, HY; Ali, I | 2 |
| Engelen, M; Rochette, F; Vanden Bossche, H | 1 |
| Kurdina, MI | 1 |
| Chiap, P; Crommen, J; Hubert, P | 1 |
| Hayashi, H; Katoh, H; Ohashi, K; Ozeki, M; Satoh, H; Takeuchi, K; Terada, H; Tran, QK; Uehara, A; Watanabe, H | 1 |
| Gangneux, JP; Guiguen, C; Preney, L; Théraud, M | 1 |
| Carrillo-Muñoz, AJ; Casals, J; del Valle, O; Guardià, C; Guglietta, A; Palacín, C; Quindós, G; Rodríguez, V | 1 |
| Holmén, J; Landgren, M; Mårdh, PA; Wågström, J | 1 |
| Crawford, F | 2 |
| Jiang, N; Liu, L; Zhang, C; Zhang, YL; Zhang, ZC; Zhang, ZM | 1 |
| Castro-Puyana, M; Crego, AL; García-Ruiz, C; Marina, ML | 1 |
| Fick, J; Lindberg, RH; Tysklind, M | 1 |
| Klemm, E; Vennewald, I | 1 |
| Carroll, P; Cheesman, MR; Driscoll, MD; Howard, M; Jowitt, TA; McLean, KJ; Munro, AW; Parish, T | 1 |
| Kelly, DE; Kelly, SL; Lamb, DC; Martel, CM; Melo, N; Nes, WD; Parker, JE; Warrilow, AG | 1 |
| Bureik, M; Drăgan, CA; Maurer, HH; Neunzig, I; Peters, FT; Schwaninger, AE; Widjaja, M | 1 |
| Bolanz, KA; Hediger, MA; Landowski, CP; Suzuki, Y | 1 |
| Busto, E; Gotor, V; Gotor-Fernández, V; Malpartida, F; Mangas-Sánchez, J | 1 |
| Huang, Q; Peng, X; Wang, C; Wang, Z; Yu, Y; Zhang, K | 1 |
| Baloğlu, E; Eraç, B; Gürsel, O; Karavana, SY; Limoncu, MH; Senyiğit, ZA | 1 |
| Cheng, X; Hu, Z; Zhang, J | 1 |
| Deng, M; Guo, X; Jiang, Z; Liu, Y; Yu, J | 1 |
| Brackman, G; Cappoen, D; Coenye, T; Cos, P; Crabbé, A; Rigole, P; Van den Driessche, F; Vanhoutte, B; Vercruysse, J; Verstraete, G; Vervaet, C | 1 |
| Eldridge, DS; Harding, IH; Palombo, EA; Shah, RM | 1 |
| Rathinasamy, K; Sebastian, J | 1 |
| Abastabar, M; Aghili, SR; Badali, H; Haghani, I; Hedayati, MT; Javidnia, J; Khojasteh, S; Meis, JF; Moazeni, M; Nargesi, S; Nosratabadi, M; Shabanzadeh, S; Shokohi, T; Zaedi, A | 1 |
| Carlson, HA; Liu, J; Scott, EE | 1 |
6 review(s) available for econazole and miconazole
| Article | Year |
|---|---|
Strategies for the development of highly selective cytochrome P450 inhibitors: Several CYP targets in current research.
Topics: Animals; Binding Sites; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Development; Heme; Humans; Hydrophobic and Hydrophilic Interactions; Protein Binding | 2019 |
Antifungal agents.
Topics: Amphotericin B; Antifungal Agents; Clotrimazole; Econazole; Flucytosine; Griseofulvin; Humans; Imidazoles; Intestinal Absorption; Miconazole; Nystatin; Peptides; Polyenes | 1978 |
Antifungal agents of use in animal health--chemical, biochemical and pharmacological aspects.
Topics: Animals; Antifungal Agents; Clotrimazole; Drug Resistance, Fungal; Econazole; Fluconazole; Flucytosine; Griseofulvin; Imidazoles; Itraconazole; Ketoconazole; Miconazole; Naphthalenes; Natamycin; Nystatin; Terbinafine; Thiabendazole; Tolnaftate; Veterinary Drugs | 2003 |
Athlete's foot.
Topics: Allylamine; Antifungal Agents; Clotrimazole; Econazole; Humans; Imidazoles; Miconazole; Naphthalenes; Terbinafine; Tinea Pedis | 2005 |
Otomycosis: Diagnosis and treatment.
Topics: Administration, Topical; Amphotericin B; Anti-Infective Agents; Antifungal Agents; Clotrimazole; Drug Resistance, Fungal; Econazole; Humans; Itraconazole; Miconazole; Mycoses; Ointments; Otitis Externa | 2010 |
Athlete's foot.
Topics: Administration, Oral; Administration, Topical; Clotrimazole; Drug Administration Schedule; Econazole; Evidence-Based Medicine; Humans; Hygiene; Miconazole; Tinea Pedis | 2009 |
6 trial(s) available for econazole and miconazole
| Article | Year |
|---|---|
Evaluation of skin irritation and contact sensitizing potential of fenticonazole.
Topics: Adult; Dermatitis, Contact; Drug Evaluation; Econazole; Female; Humans; Imidazoles; Irritants; Male; Miconazole; Skin Tests | 1990 |
Is more than one application of an antifungal necessary in the treatment of acute vaginal candidiasis?
Topics: Amphotericin B; Antifungal Agents; Candidiasis, Vulvovaginal; Clinical Trials as Topic; Clotrimazole; Double-Blind Method; Drug Administration Schedule; Econazole; Female; Follow-Up Studies; Humans; Imidazoles; Miconazole; Nystatin; Pessaries; Recurrence; Vaginal Creams, Foams, and Jellies; Wales | 1985 |
Comparison of econazole and isoconazole as single dose treatment for vaginal candidosis.
Topics: Adult; Candidiasis, Vulvovaginal; Clinical Trials as Topic; Econazole; Female; Humans; Imidazoles; Miconazole | 1985 |
Vulvovaginal candidiasis: treatment and recurrence.
Topics: Adolescent; Adult; Antifungal Agents; Candidiasis, Vulvovaginal; Child; Clotrimazole; Econazole; Female; Humans; Miconazole; Middle Aged; Nystatin; Recurrence; Vaginal Creams, Foams, and Jellies | 1982 |
Tinea versicolor: new topical treatments.
Topics: Administration, Topical; Double-Blind Method; Econazole; Humans; Imidazoles; Miconazole; Placebos; Tinea Versicolor | 1980 |
[Comparison of various types of imidazole derivatives for treatment of filamentous fungal keratitis].
Topics: Adolescent; Adult; Antifungal Agents; Drug Therapy, Combination; Econazole; Eye Infections, Fungal; Female; Humans; Keratitis; Male; Miconazole; Middle Aged | 1996 |
132 other study(ies) available for econazole and miconazole
| Article | Year |
|---|---|
Synthesis and antifungal activity of a series of novel 1,2-disubstituted propenones.
Topics: Animals; Aspergillus fumigatus; Candida albicans; Candidiasis; Chemical Phenomena; Chemistry; Fungi; Ketones; Mice; Propiophenones; Structure-Activity Relationship; Trichophyton | 1987 |
Three dimensional pharmacophore modeling of human CYP17 inhibitors. Potential agents for prostate cancer therapy.
Topics: Algorithms; Antineoplastic Agents; Azoles; Binding Sites; Enzyme Inhibitors; Humans; Hydrogen Bonding; Male; Models, Molecular; Prostatic Neoplasms; Protein Binding; Quantitative Structure-Activity Relationship; Steroid 17-alpha-Hydroxylase; Steroids | 2003 |
Identification and prediction of promiscuous aggregating inhibitors among known drugs.
Topics: Antifungal Agents; beta-Lactamase Inhibitors; Chemical Phenomena; Chemistry, Physical; Chymotrypsin; Enzyme Inhibitors; Kinetics; Light; Malate Dehydrogenase; Models, Molecular; Molecular Conformation; Scattering, Radiation; Structure-Activity Relationship | 2003 |
Imidazole analogues of fluoxetine, a novel class of anti-Candida agents.
Topics: Antifungal Agents; Candida albicans; Cell Line, Tumor; Cell Survival; Fluoxetine; Humans; Imidazoles; Microbial Sensitivity Tests; Structure-Activity Relationship | 2004 |
Inhibition of the enzymatic activity of heme oxygenases by azole-based antifungal drugs.
Topics: Animals; Antifungal Agents; Enzyme Inhibitors; Heme Oxygenase (Decyclizing); Ketoconazole; Kinetics; Male; Microsomes, Liver; Rats; Rats, Sprague-Dawley | 2006 |
Three-dimensional quantitative structure-activity relationship analysis of human CYP51 inhibitors.
Topics: Amides; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Humans; Indoles; Models, Molecular; Oxidoreductases; Quantitative Structure-Activity Relationship; Sterol 14-Demethylase | 2007 |
1-[(3-Aryloxy-3-aryl)propyl]-1H-imidazoles, new imidazoles with potent activity against Candida albicans and dermatophytes. Synthesis, structure-activity relationship, and molecular modeling studies.
Topics: Antifungal Agents; Arthrodermataceae; Candida albicans; Cell Line, Tumor; Cell Survival; Computer Simulation; Humans; Imidazoles; Models, Molecular; Molecular Structure; Stereoisomerism; Structure-Activity Relationship | 2008 |
Differential azole antifungal efficacies contrasted using a Saccharomyces cerevisiae strain humanized for sterol 14 alpha-demethylase at the homologous locus.
Topics: Antifungal Agents; Azoles; Base Sequence; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; DNA, Fungal; Drug Resistance, Fungal; Genes, Fungal; Humans; Molecular Sequence Data; Recombinant Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Species Specificity; Sterol 14-Demethylase | 2008 |
A nonsense mutation in the ERG6 gene leads to reduced susceptibility to polyenes in a clinical isolate of Candida glabrata.
Topics: Antifungal Agents; Azoles; Base Sequence; Candida glabrata; Candidiasis; Codon, Nonsense; DNA, Fungal; Drug Resistance, Fungal; Ergosterol; Genes, Fungal; Guanine; Humans; Molecular Sequence Data; Polyenes | 2008 |
Identification, characterization, and azole-binding properties of Mycobacterium smegmatis CYP164A2, a homolog of ML2088, the sole cytochrome P450 gene of Mycobacterium leprae.
Topics: Amino Acid Motifs; Amino Acid Sequence; Azoles; Base Sequence; Cloning, Molecular; Conserved Sequence; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Genes, Bacterial; Hydrogen-Ion Concentration; Molecular Sequence Data; Molecular Structure; Molecular Weight; Mycobacterium leprae; Mycobacterium smegmatis; Osmolar Concentration; Recombinant Proteins; Sequence Homology, Amino Acid; Sodium Chloride | 2009 |
Comparative chemometric modeling of cytochrome 3A4 inhibitory activity of structurally diverse compounds using stepwise MLR, FA-MLR, PLS, GFA, G/PLS and ANN techniques.
Topics: Algorithms; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Enzyme Inhibitors; Factor Analysis, Statistical; Least-Squares Analysis; Linear Models; Models, Molecular; Neural Networks, Computer; Quantitative Structure-Activity Relationship; Reproducibility of Results | 2009 |
Hypersusceptibility to azole antifungals in a clinical isolate of Candida glabrata with reduced aerobic growth.
Topics: Adult; Aerobiosis; Antifungal Agents; Azoles; Candida glabrata; Chromatography, High Pressure Liquid; Ergosterol; Female; Flow Cytometry; Genes, Fungal; Humans; Microbial Sensitivity Tests; Microscopy, Electron, Transmission; Molecular Sequence Data; Polyenes | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Prediction and evaluation of protein farnesyltransferase inhibition by commercial drugs.
Topics: Animals; Cell Line; Dose-Response Relationship, Drug; Enzyme Inhibitors; Farnesyltranstransferase; Green Fluorescent Proteins; Histamine H1 Antagonists, Non-Sedating; Ligands; Loratadine; Miconazole; Microscopy, Confocal; Molecular Structure; Pharmaceutical Preparations; Protein Interaction Mapping; Protein Prenylation; ras Proteins; Recombinant Fusion Proteins; Technology, Pharmaceutical | 2010 |
Structural and biochemical characterization of Mycobacterium tuberculosis CYP142: evidence for multiple cholesterol 27-hydroxylase activities in a human pathogen.
Topics: Cholesterol; Crystallography, X-Ray; Cytochrome P-450 Enzyme System; Host-Pathogen Interactions; Humans; Hydroxylation; Mycobacterium tuberculosis; Oxidation-Reduction; Protein Structure, Tertiary | 2010 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Identification of selective inhibitors of indoleamine 2,3-dioxygenase 2.
Topics: Animals; Dose-Response Relationship, Drug; Enzyme Inhibitors; HEK293 Cells; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Mice; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Substrate Specificity | 2012 |
Detailed analysis and follow-up studies of a high-throughput screening for indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors.
Topics: Animals; Antifungal Agents; Dose-Response Relationship, Drug; Enzyme Inhibitors; High-Throughput Screening Assays; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Mice; Molecular Dynamics Simulation; Molecular Structure; Structure-Activity Relationship | 2014 |
The Effect of Small Molecules on Sterol Homeostasis: Measuring 7-Dehydrocholesterol in Dhcr7-Deficient Neuro2a Cells and Human Fibroblasts.
Topics: Animals; Cell Line; Dehydrocholesterols; Dose-Response Relationship, Drug; Fibroblasts; Homeostasis; Humans; Mice; Molecular Conformation; Neurons; Oxidoreductases Acting on CH-CH Group Donors; Small Molecule Libraries; Sterols; Structure-Activity Relationship | 2016 |
Fragment-Based Approaches to the Development of Mycobacterium tuberculosis CYP121 Inhibitors.
Topics: Bacterial Proteins; Binding Sites; Crystallography, X-Ray; Cytochrome P-450 Enzyme System; Drug Design; Enzyme Inhibitors; Humans; Ligands; Mycobacterium tuberculosis; Protein Binding; Protein Structure, Tertiary; Tuberculosis | 2016 |
Evaluation of known and novel inhibitors of Orai1-mediated store operated Ca
Topics: Calcium Channel Blockers; Cell Line, Tumor; Databases, Chemical; Drug Stability; Fluorescence; HEK293 Cells; High-Throughput Screening Assays; Humans; ORAI1 Protein; Stereoisomerism; Structure-Activity Relationship; Triazoles | 2017 |
Investigation of multi-target-directed ligands (MTDLs) with butyrylcholinesterase (BuChE) and indoleamine 2,3-dioxygenase 1 (IDO1) inhibition: The design, synthesis of miconazole analogues targeting Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Butyrylcholinesterase; Dose-Response Relationship, Drug; Drug Design; Electrophorus; Enzyme Inhibitors; Horses; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Ligands; Miconazole; Molecular Docking Simulation; Molecular Structure; Structure-Activity Relationship | 2018 |
The activity in vitro of five different antimycotics against Pityrosporum orbiculare.
Topics: Antifungal Agents; Clotrimazole; Cyclic N-Oxides; Econazole; Malassezia; Miconazole; Microbial Sensitivity Tests; Pharmaceutical Vehicles; Pyridines; Solvents; Thiones; Thiosulfates | 1979 |
[Therapy of opportunistic mycoses].
Topics: Adult; Amphotericin B; Antifungal Agents; Drug Evaluation; Econazole; Flucytosine; Humans; Miconazole; Mycoses; Nystatin | 1979 |
[Recent progress in the treatment of systemic mycotic infections].
Topics: Antifungal Agents; Clotrimazole; Econazole; Flucytosine; Humans; Miconazole; Mycoses | 1979 |
Pharmacokinetics of imidazole antimycotics.
Topics: Adult; Animals; Antifungal Agents; Child; Clotrimazole; Econazole; Fungi; Guinea Pigs; Humans; Imidazoles; Kinetics; Mice; Miconazole; Rabbits; Time Factors | 1979 |
[Keratomycoses].
Topics: Corneal Diseases; Econazole; Humans; Keratitis; Miconazole; Mycoses | 1979 |
R34000, a dioxolane imidazole in the therapy for experimental coccidioidomycosis. Comparison with miconazole and econazole.
Topics: Administration, Oral; Animals; Coccidioides; Coccidioidomycosis; Dioxolanes; Dioxoles; Disease Models, Animal; Econazole; Female; Imidazoles; Injections, Intravenous; Mice; Miconazole; Microbial Sensitivity Tests | 1976 |
Inhibition of voltage-gated Ca2+ entry into GH3 and chromaffin cells by imidazole antimycotics and other cytochrome P450 blockers.
Topics: Animals; Biological Transport; Calcium; Calcium Channels; Carbon Monoxide; Cattle; Cells, Cultured; Chromaffin System; Cytochrome P-450 Enzyme Inhibitors; Econazole; Manganese; Membrane Potentials; Miconazole; Pituitary Gland | 1992 |
Calcium influx evoked by Ca2+ store depletion in human platelets is more susceptible to cytochrome P-450 inhibitors than receptor-mediated calcium entry.
Topics: Adenosine Diphosphate; Blood Platelets; Calcium; Calcium Channels; Calcium-Transporting ATPases; Cell Compartmentation; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Econazole; Humans; Hydroquinones; Inositol 1,4,5-Trisphosphate; Intracellular Fluid; Ion Channel Gating; Manganese; Miconazole; Osmolar Concentration; Platelet Activating Factor; Platelet Activation; Receptors, Cholinergic; Ryanodine Receptor Calcium Release Channel; Signal Transduction; Terpenes; Thapsigargin; Thrombin; Vasopressins | 1992 |
In vitro activity of cloconazole, sulconazole, butoconazole, isoconazole, fenticonazole, and five other antifungal agents against clinical isolates of Candida albicans and Candida spp.
Topics: Amphotericin B; Antifungal Agents; Candida; Candida albicans; Econazole; Flucytosine; Imidazoles; Ketoconazole; Miconazole; Microbial Sensitivity Tests | 1992 |
Agonist-evoked Ca2+ entry in human platelets.
Topics: Adenosine Diphosphate; Biological Transport; Blood Platelets; Calcium; Cell Membrane; Econazole; Humans; Imidazoles; Manganese; Miconazole; Platelet Aggregation Inhibitors | 1992 |
Antimycotic imidazoles: X-ray powder diffraction data for econazole and miconazole.
Topics: Econazole; Miconazole; Powders; X-Ray Diffraction | 1991 |
The in vitro activity of terconazole against yeasts: its topical long-acting therapeutic efficacy in experimental vaginal candidiasis in rats.
Topics: Administration, Topical; Amphotericin B; Animals; Antifungal Agents; Candida; Candidiasis, Vulvovaginal; Clotrimazole; Econazole; Female; Miconazole; Microbial Sensitivity Tests; Nystatin; Rats; Rats, Inbred Strains; Triazoles | 1991 |
In vitro antimicrobial activity of econazole and miconazole sulfosalicylate.
Topics: Animals; Arthrodermataceae; Aspergillus flavus; Aspergillus fumigatus; Candida; Econazole; Enterococcus faecalis; Miconazole; Microbial Sensitivity Tests; Staphylococcus aureus; Trichomonas vaginalis | 1990 |
[Trends in the search for new compounds with potential anti- trichomonal and anti-fungal effects].
Topics: Animals; Antifungal Agents; Antitrichomonal Agents; Candida; Culture Media; Drug Evaluation, Preclinical; Econazole; In Vitro Techniques; Miconazole; Trichomonas | 1990 |
In vitro antifungal activities of new imidazole salts towards dermatophytes.
Topics: Arthrodermataceae; Econazole; Miconazole; Salicylates | 1990 |
Analysis of miconazole and econazole in pharmaceutical formulations by derivative UV spectroscopy and liquid chromatography (HPLC).
Topics: Chromatography, High Pressure Liquid; Econazole; Indicators and Reagents; Miconazole; Ointments; Powders; Spectrophotometry, Ultraviolet | 1989 |
Azole sensitivity in Candida albicans.
Topics: Antifungal Agents; Azoles; Candida albicans; Drug Resistance, Microbial; Econazole; Genes, Fungal; Ketoconazole; Miconazole; Microbial Sensitivity Tests; Mutation; Protoplasts; Species Specificity | 1989 |
Sensitivity of some strains of the genus Epidermophyton to different antifungal agents.
Topics: Antifungal Agents; Clotrimazole; Econazole; Epidermophyton; Griseofulvin; Imidazoles; Ketoconazole; Miconazole; Natamycin; Nystatin | 1989 |
Contact allergy to imidazole antimycotics.
Topics: Adult; Aged; Antifungal Agents; Chemical Phenomena; Chemistry; Clotrimazole; Drug Eruptions; Econazole; Female; Humans; Imidazoles; Male; Miconazole; Middle Aged; Prospective Studies | 1988 |
Azole resistance in Candida albicans.
Topics: Adult; Animals; Antifungal Agents; Candida albicans; Candidiasis; Candidiasis, Chronic Mucocutaneous; Disease Models, Animal; Drug Resistance, Microbial; Econazole; Female; Fluconazole; Guinea Pigs; Humans; Imidazoles; Itraconazole; Ketoconazole; Male; Mice; Miconazole; Rats; Rats, Inbred Strains; Triazoles | 1986 |
[Comparative action of 8 azole derivatives against Candida albicans: fungistatic action and cytologic study by scanning electron microscopy].
Topics: Antifungal Agents; Candida albicans; Clotrimazole; Cytoplasm; Econazole; Imidazoles; Ketoconazole; Miconazole; Microbial Sensitivity Tests; Microscopy, Electron, Scanning; Spheroplasts; Triazoles | 1988 |
Antifungal susceptibility testing of Trichosporon beigelii to imidazole compounds.
Topics: Amphotericin B; Clotrimazole; Culture Media; Econazole; Genital Diseases, Male; Hair; Humans; Imidazoles; Ketoconazole; Male; Miconazole; Microbial Sensitivity Tests; Mitosporic Fungi; Mycoses; Piedra; Scrotum; Trichosporon | 1988 |
[In vitro study on the validity of the use of antimycograms in the target treatment of superficial candidiasis].
Topics: Adolescent; Adult; Aged; Antifungal Agents; Candida; Candidiasis, Cutaneous; Child; Ciclopirox; Clotrimazole; Econazole; Female; Humans; Imidazoles; Male; Miconazole; Middle Aged; Nystatin; Pyridones | 1988 |
[Local therapy of pityriasis versicolor with 3 imidazole derivatives--results of a therapeutic study. Studies of the rate of recurrence].
Topics: Administration, Topical; Adult; Clotrimazole; Econazole; Follow-Up Studies; Humans; Imidazoles; Male; Miconazole; Recurrence; Tinea Versicolor | 1988 |
Effect of antifungal agents on lipid biosynthesis and membrane integrity in Candida albicans.
Topics: Allylamine; Animals; Antifungal Agents; Candida albicans; Cell Membrane; Cerulenin; Cholestadienols; Chromatography, Gas; Chromatography, Thin Layer; Clotrimazole; Culture Techniques; Econazole; Ergosterol; Fatty Acids; Ketoconazole; Lipids; Miconazole; Tolnaftate | 1987 |
In vitro sensitivity of environmental isolates of pathogenic dematiaceous fungi to azole compounds and a phenylpropyl-morpholine derivative.
Topics: Animals; Antifungal Agents; Culture Media; Econazole; Fungi; Imidazoles; Ketoconazole; Mice; Miconazole; Microbial Sensitivity Tests; Morpholines; Thiabendazole; Triazoles | 1987 |
Broad spectrum antifungal agents in otomycosis.
Topics: Antifungal Agents; Ciclopirox; Clotrimazole; Ear Diseases; Econazole; Fungi; Humans; Miconazole; Microbial Sensitivity Tests; Mycoses; Pyridones | 1986 |
In vitro sensitivity of Malassezia spp. to various antimycotics.
Topics: Amphotericin B; Animals; Antifungal Agents; Clotrimazole; Dog Diseases; Dogs; Econazole; Humans; Ketoconazole; Malassezia; Miconazole; Microbial Sensitivity Tests; Nystatin; Otitis; Tinea Versicolor | 1985 |
Antifungal drugs affecting the chemotaxis of polymorphonuclear neutrophils.
Topics: Antifungal Agents; Cell Extracts; Chemotaxis, Leukocyte; Clotrimazole; Complement System Proteins; Econazole; Griseofulvin; Humans; Ketoconazole; Miconazole; Natamycin; Neutrophils; Trichophyton | 1985 |
Antifungal relative inhibition factors: BAY l-9139, bifonazole, butoconazole, isoconazole, itraconazole (R 51211), oxiconazole, Ro 14-4767/002, sulconazole, terconazole and vibunazole (BAY n-7133) compared in vitro with nine established antifungal agents.
Topics: Antifungal Agents; Aspergillus; Candida; Clotrimazole; Econazole; Imidazoles; In Vitro Techniques; Itraconazole; Ketoconazole; Miconazole; Morpholines; Triazoles | 1984 |
[Local treatment of rosacea with imidazole derivatives].
Topics: Administration, Topical; Adult; Aged; Clotrimazole; Econazole; Female; Humans; Imidazoles; Male; Metronidazole; Miconazole; Middle Aged; Rosacea | 1983 |
Biochemical and ultrastructural alterations produced by miconazole and econazole in Trypanosoma cruzi.
Topics: Agglutination; Animals; Cell Nucleus; Dose-Response Relationship, Drug; Econazole; Hydrogen Peroxide; Imidazoles; Lectins; Miconazole; Sterols; Superoxides; Trypanosoma cruzi | 1981 |
Inhibition and induction of microsomal enzymes in rat. A comparative study of four antimycotics: miconazole, econazole, clotrimazole and ketoconazole.
Topics: Animals; Antifungal Agents; Clotrimazole; Econazole; Enzyme Induction; Enzyme Inhibitors; Imidazoles; Ketoconazole; Male; Miconazole; Microsomes, Liver; Pharmaceutical Preparations; Piperazines; Rats | 1981 |
A comparison of the effects of several antifungal imidazole derivatives and polyenes on Candida albicans: an ultrastructural study by scanning electron microscopy.
Topics: Amphotericin B; Antifungal Agents; Candida albicans; Cell Membrane; Cell Wall; Clotrimazole; Econazole; Imidazoles; Ketoconazole; Miconazole; Microscopy, Electron, Scanning; Nystatin; Piperazines | 1982 |
[Antimycotic therapy. 2. Antimycotic chemotherapeutic agents: imidazole derivatives, tolciclate, haloprogin, ciclopiroxolamin].
Topics: Antifungal Agents; Chemical Phenomena; Chemistry; Ciclopirox; Clotrimazole; Dermatomycoses; Econazole; Humans; Imidazoles; Ketoconazole; Miconazole; Phenyl Ethers; Piperazines; Pyridones; Thiocarbamates | 1983 |
Comparative susceptibility of the agents of adiaspiromycosis to imidazole derivatives in vitro.
Topics: Antifungal Agents; Chrysosporium; Clotrimazole; Econazole; Imidazoles; Ketoconazole; Miconazole; Mitosporic Fungi; Spores, Fungal | 1983 |
The effect of imidazoles on germination of arthrospores and microconidia of Trichophyton mentagrophytes.
Topics: Clotrimazole; Econazole; Imidazoles; Ketoconazole; Miconazole; Microbial Sensitivity Tests; Spores, Fungal; Trichophyton | 1984 |
Influence of the corneal epithelium on the efficacy of topical antifungal agents.
Topics: Administration, Topical; Amphotericin B; Animals; Antifungal Agents; Candidiasis; Cornea; Corneal Diseases; Econazole; Epithelium; Flucytosine; Ketoconazole; Miconazole; Natamycin; Rabbits | 1984 |
Are econazole, miconazole and clotrimazole mutagenic to bacteria?
Topics: Bacteria; Clotrimazole; Econazole; Escherichia coli; Imidazoles; Klebsiella pneumoniae; Miconazole; Microbial Sensitivity Tests; Mutagenicity Tests; Mutation; Salmonella typhimurium | 1983 |
Comparison of the in vitro antifungal activities of clotrimazole, miconazole, econazole and exalamide against clinical isolates of dermatophytes.
Topics: Antifungal Agents; Arthrodermataceae; Benzamides; Clotrimazole; Econazole; Humans; In Vitro Techniques; Miconazole | 1984 |
Chlorination-induced enhancement of biological activities in imidazole antimycotics. A possible explanation to the molecular mechanism for their antimycotic activities.
Topics: Animals; Antifungal Agents; Chemical Phenomena; Chemistry; Chlorine; Clotrimazole; Econazole; Imidazoles; In Vitro Techniques; Miconazole; Mitochondria, Liver; Mitochondrial Swelling; Oxidative Phosphorylation; Rats; Structure-Activity Relationship | 1983 |
Tioconazole in the treatment of fungal infections of the skin. An international clinical research program.
Topics: Adolescent; Antifungal Agents; Clotrimazole; Dermatomycoses; Drug Evaluation; Econazole; Erythrasma; Female; Humans; Imidazoles; Male; Miconazole; Pharmaceutical Vehicles; Tinea | 1983 |
[Comparison of the in vitro antifungal activities of clotrimazole, miconazole, Econazole and exalamide against clinical isolates of dermatophytes (author's transl)].
Topics: Antifungal Agents; Arthrodermataceae; Benzamides; Clotrimazole; Econazole; Humans; Imidazoles; Miconazole | 1982 |
[Diagnosis and therapy of vulvovaginal mycosis (author's transl)].
Topics: Adult; Antifungal Agents; Bacteriological Techniques; Candidiasis, Vulvovaginal; Econazole; Female; Humans; Imidazoles; Miconazole; Mycoses; Pregnancy; Vaginitis | 1981 |
[The antimycotica disc elution test: a new quantitative antimycotica test for yeasts (author's transl)].
Topics: Antifungal Agents; Candida albicans; Clotrimazole; Econazole; Flucytosine; Miconazole; Microbial Sensitivity Tests | 1982 |
[Cytological study of the action of imidazoles on Candida albicans (author's transl)].
Topics: Antifungal Agents; Candida albicans; Cell Membrane; Cell Wall; Clotrimazole; Econazole; Imidazoles; Miconazole; Microscopy, Electron, Scanning; Spheroplasts | 1982 |
The role of econazole in the management of oculomycosis.
Topics: Animals; Candidiasis; Clotrimazole; Corneal Diseases; Disease Models, Animal; Econazole; Fungi; Imidazoles; In Vitro Techniques; Male; Miconazole; Mycoses; Rabbits | 1982 |
In vivo antimycotic activity of naftifine.
Topics: Animals; Antifungal Agents; Dermatomycoses; Econazole; Guinea Pigs; Male; Miconazole; Tolnaftate | 1981 |
[New antifungal agents: econazole and micronazole].
Topics: Antifungal Agents; Econazole; Humans; Imidazoles; Miconazole | 1980 |
[In vitro demonstration of the antibacterial and antimycotic efficacy of a preparation containing nystatin and chlorquinaldol compared with similar antimicrobial agents (author's transl)].
Topics: Bacteria; Chlorquinaldol; Clotrimazole; Drug Combinations; Econazole; Fungi; Miconazole; Nystatin; Species Specificity; Tolnaftate | 1980 |
Antifungal antibiotic sensitivity testing: use of Autobac 1 for standardization purposes.
Topics: Amphotericin B; Antifungal Agents; Candida; Clotrimazole; Econazole; Flucytosine; Miconazole; Microbial Sensitivity Tests; Nystatin | 1980 |
[A case of hypersensitivity to miconazole, econazole, and tolciclate (author's transl)].
Topics: Drug Hypersensitivity; Econazole; Hand Dermatoses; Humans; Imidazoles; Male; Miconazole; Middle Aged; Mycoses | 1980 |
Effect of anti-fungal imidazoles on mRNA levels and enzyme activity of inducible nitric oxide synthase.
Topics: Amino Acid Oxidoreductases; Animals; Cells, Cultured; Clotrimazole; Econazole; Enzyme Induction; Macrophages; Mice; Miconazole; Nitric Oxide Synthase; Nitrites; RNA, Messenger | 1994 |
The imidazole antimycotics econazole and miconazole reduce agonist-evoked protein-tyrosine phosphorylation and evoke membrane depolarisation in human platelets: cautions for their use in studying Ca2+ signalling pathways.
Topics: Adenosine Diphosphate; Benzothiazoles; Blood Platelets; Calcium; Carbocyanines; Cell Membrane; Cytochrome P-450 Enzyme Inhibitors; Econazole; Fluorescent Dyes; Humans; Membrane Potentials; Miconazole; Phosphorylation; Phosphotyrosine; Signal Transduction; Tyrosine | 1994 |
Allergic contact dermatitis from sertaconazole with cross-sensitivity to miconazole and econazole.
Topics: Adult; Antifungal Agents; Cross Reactions; Dermatitis, Allergic Contact; Econazole; Humans; Imidazoles; Male; Miconazole; Thiophenes | 1995 |
Effect of different inhibitors of sterol biosynthesis on both fungal growth and aflatoxin production.
Topics: Aflatoxins; Antifungal Agents; Aspergillus; Culture Media; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Econazole; Ergosterol; Fatty Acids; Itraconazole; Ketoconazole; Miconazole | 1995 |
Toxicity of antibiotics and antifungals on cultured human corneal cells: effect of mixing, exposure and concentration.
Topics: Anti-Bacterial Agents; Cell Division; Cell Survival; Cells, Cultured; Chloramphenicol; Clotrimazole; Cornea; Dose-Response Relationship, Drug; Drug Therapy, Combination; Econazole; Gentamicins; Humans; Methicillin; Miconazole | 1995 |
[Enantioselective synthesis and antifungal activity of optically active econazole and miconazole].
Topics: Candida albicans; Econazole; Miconazole; Microsporum; Stereoisomerism; Trichophyton | 1993 |
Inhibition of Ca2+ transport pathways in thymic lymphocytes by econazole, miconazole, and SKF 96365.
Topics: Animals; Biological Transport; Calcium; Calcium-Transporting ATPases; Cell Membrane Permeability; Cells, Cultured; Cytochrome P-450 Enzyme Inhibitors; Econazole; Fluorescence; Imidazoles; Lymphocytes; Male; Miconazole; Oxidation-Reduction; Proton Pump Inhibitors; Rats; Rats, Wistar; Sarcoplasmic Reticulum; Terpenes; Thapsigargin; Thymus Gland | 1993 |
Antimycotic susceptibility testing of agents of black grain eumycetoma.
Topics: Antifungal Agents; Econazole; Fungi; Humans; Itraconazole; Ketoconazole; Miconazole; Microbial Sensitivity Tests; Mycoses; Species Specificity | 1993 |
Direct interaction of antifungal azole-derivatives with calmodulin: a possible mechanism for their therapeutic activity.
Topics: Antifungal Agents; Calmodulin; Clotrimazole; Drug Interactions; Econazole; Imidazoles; Ketoconazole; Kinetics; Miconazole; Phosphodiesterase Inhibitors; Polymyxin B | 1993 |
Imidazole antimycotics inhibitors of cytochrome P450 increase phosphatidylserine synthesis similarly to K(+)-channel blockers in Jurkat T cells.
Topics: Antifungal Agents; Benzoflavones; Calcium; CD3 Complex; Cell Line; Clotrimazole; Cytochrome P-450 Enzyme Inhibitors; Econazole; Humans; Imidazoles; Membrane Potentials; Miconazole; Phosphatidylserines; Potassium Channels; Serine; T-Lymphocytes; Valinomycin | 1993 |
Modulation of human T-lymphocyte plasma membrane Ca2+ permeability by imidazole antimycotics.
Topics: Antifungal Agents; Calcium; Cell Membrane Permeability; Clotrimazole; Cytochrome P-450 Enzyme Inhibitors; Econazole; Enzyme Inhibitors; Humans; Imidazoles; Miconazole; T-Lymphocytes; Thapsigargin | 1996 |
On-line post-column photochemical derivatization in liquid chromatographic--diode-array detection analysis of binary drug mixtures.
Topics: Administration, Topical; Anti-Inflammatory Agents; Betamethasone Valerate; Chlorhexidine; Chromatography, Liquid; Clotrimazole; Cresols; Desonide; Dexamethasone; Econazole; Hydrocortisone; Miconazole; Ointments; Photochemistry; Spectrophotometry, Ultraviolet; Triamcinolone Acetonide | 1996 |
High D-glucose-induced changes in endothelial Ca2+/EDRF signaling are due to generation of superoxide anions.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Aorta; Bradykinin; Calcium; Cells, Cultured; Cyclic GMP; Cytochalasin B; Deferoxamine; Econazole; Endothelium, Vascular; Enzyme Inhibitors; Glucose; Gossypol; Imidazoles; Imidazolidines; Indomethacin; Kinetics; Masoprocol; Miconazole; Nitric Oxide; Nitric Oxide Synthase; Signal Transduction; Superoxides; Swine; Time Factors | 1996 |
Rapid high performance liquid chromatographic assay for antifungal agents in human sera.
Topics: Amphotericin B; Antifungal Agents; Chromatography, High Pressure Liquid; Econazole; Fluconazole; Flucytosine; Humans; Itraconazole; Ketoconazole; Miconazole; Spectrophotometry, Ultraviolet | 1996 |
Calmidazolium and other imidazole compounds affect steroidogenesis in Y1 cells: lack of involvement of the peripheral-type benzodiazepine receptor.
Topics: Adrenal Cortex; Animals; Binding, Competitive; Cholesterol Side-Chain Cleavage Enzyme; Dose-Response Relationship, Drug; Drug Interactions; Econazole; Imidazoles; Isoquinolines; Ligands; Mice; Miconazole; Pregnenolone; Receptors, GABA-A | 1997 |
Econazole, miconazole and SK & F 96365 inhibit depolarization-induced and receptor-operated contraction of guinea-pig isolated trachea in vitro.
Topics: Animals; Calcium Channel Blockers; Econazole; Egtazic Acid; Female; Guinea Pigs; Histamine; Imidazoles; In Vitro Techniques; Male; Methacholine Compounds; Miconazole; Muscle Contraction; Muscle, Smooth; Neuromuscular Depolarizing Agents; Potassium Chloride; Trachea | 1997 |
Antimicrobial sensitivity in microorganisms isolated from canine otitis externa.
Topics: Amphotericin B; Animals; Antifungal Agents; Dog Diseases; Dogs; Econazole; Miconazole; Microbial Sensitivity Tests; Nystatin; Otitis Externa | 1997 |
[Effect of imidazole antifungal agents on colony formation by murine bone marrow CFUc (colony forming units in culture].
Topics: Animals; Antifungal Agents; Bone Marrow Cells; Cells, Cultured; Clotrimazole; Colony-Forming Units Assay; Econazole; Hematopoietic Stem Cells; Humans; Imidazoles; Ketoconazole; Mice; Miconazole | 1996 |
Inhibition of platelet serotonin uptake by cytochrome P450 inhibitors miconazole and econazole.
Topics: Benzoflavones; beta-Naphthoflavone; Blood Platelets; Calcium; Clotrimazole; Cytochrome P-450 Enzyme Inhibitors; Drug Combinations; Drugs, Chinese Herbal; Econazole; Enzyme Inhibitors; Glycyrrhiza; Humans; Miconazole; Paeonia; Serotonin | 1998 |
Capacitative Ca2+ entry into Xenopus oocytes is sensitive to omega-conotoxins GVIA, MVIIA and MVIIC.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Acetates; Animals; Bungarotoxins; Calcium; Calcium Channel Blockers; Calcium Channels; Chlorides; Econazole; Elapid Venoms; Ethylenediamines; Flunarizine; Imidazoles; Inositol 1,4,5-Trisphosphate; Ion Transport; Lanthanum; Miconazole; Niflumic Acid; omega-Conotoxin GVIA; omega-Conotoxins; Oocytes; Patch-Clamp Techniques; Peptides; Phosphatidylinositols; Photolysis; Signal Transduction; Xenopus laevis | 1998 |
Disk diffusion susceptibility testing of dermatophytes with imidazoles.
Topics: Antifungal Agents; Arthrodermataceae; Dermatomycoses; Econazole; Griseofulvin; Humans; Imidazoles; In Vitro Techniques; Ketoconazole; Miconazole; Microbial Sensitivity Tests | 1995 |
[Study of the in vitro sensitivity of yeasts with the ATB-Fungus system].
Topics: Amphotericin B; Antifungal Agents; Candida; Cryptococcus; Econazole; Flucytosine; Ketoconazole; Miconazole; Nystatin; Saccharomyces cerevisiae; Yeasts | 1998 |
Positively and negatively charged submicron emulsions for enhanced topical delivery of antifungal drugs.
Topics: Administration, Topical; Animals; Antifungal Agents; Chemical Phenomena; Chemistry, Physical; Diffusion; Econazole; Electrochemistry; Emulsions; Excipients; Female; In Vitro Techniques; Miconazole; Particle Size; Rats; Triglycerides | 1999 |
Cyclodextrin inclusion complexes of miconazole and econazole--isolation, toxicity on human cells, and confirmation of a new interpretation of the drug supersaturation phenomenon.
Topics: Antifungal Agents; beta-Cyclodextrins; Cell Culture Techniques; Cell Line; Cell Survival; Cyclodextrins; Drug Interactions; Econazole; Erythrocytes; Hemolysis; Humans; Hydrogen-Ion Concentration; Miconazole; Mouth; Nitrates; Solubility; Temperature; Water | 1999 |
Comparison of the toxicity of fluconazole and other azole antifungal drugs to murine and human granulocyte-macrophage progenitor cells in vitro.
Topics: Animals; Antifungal Agents; Azoles; Bone Marrow; Cells, Cultured; Clotrimazole; Dose-Response Relationship, Drug; Econazole; Female; Fluconazole; Granulocytes; Hematopoietic Stem Cells; Humans; Imidazoles; Inhibitory Concentration 50; Ketoconazole; Macrophages; Male; Mice; Miconazole; Species Specificity; Stem Cells | 1999 |
In-vitro resistance to azoles associated with mitochondrial DNA deficiency in Candida glabrata.
Topics: Antifungal Agents; Azoles; Candida; Candidiasis; Clotrimazole; DNA, Fungal; DNA, Mitochondrial; Drug Resistance, Microbial; Econazole; Electrophoresis, Agar Gel; Fluconazole; Humans; Imidazoles; Ketoconazole; Miconazole; Microbial Sensitivity Tests; Polyenes | 1999 |
Inhibition of cholesteryl ester formation in macrophages by azole antimycotics.
Topics: Animals; Antifungal Agents; Azoles; Cells, Cultured; Cholesterol; Cholesterol Esters; Econazole; Endocytosis; Esterification; Female; Hydroxycholesterols; Ketoconazole; Macrophages, Peritoneal; Mice; Mice, Inbred ICR; Miconazole | 1999 |
Cyclodextrin inclusion complexes of antimycotics intended to act in the oral cavity--drug supersaturation, toxicity on TR146 cells and release from a delivery system.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Antifungal Agents; beta-Cyclodextrins; Candida albicans; Carcinoma, Squamous Cell; Cheek; Chewing Gum; Cyclodextrins; Drug Delivery Systems; Econazole; Head and Neck Neoplasms; Humans; Kinetics; Miconazole; Microscopy, Electron, Scanning; Mouth Mucosa; Mouth Neoplasms; Solubility; Tumor Cells, Cultured | 1999 |
In vitro activities of ketoconazole, econazole, miconazole, and Melaleuca alternifolia (tea tree) oil against Malassezia species.
Topics: Antifungal Agents; Econazole; Humans; Ketoconazole; Malassezia; Miconazole; Microbial Sensitivity Tests; Rosales; Tea Tree Oil | 2000 |
Amino acid 305 determines catalytic center accessibility in CYP3A4.
Topics: Alanine; Amino Acid Substitution; Aryl Hydrocarbon Hydroxylases; Binding Sites; Catalysis; Clotrimazole; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Diazepam; Econazole; Erythromycin; Humans; Imidazoles; Ketoconazole; Kinetics; Miconazole; Mixed Function Oxygenases; Multienzyme Complexes; Mutation; Nifedipine; Oxidoreductases, N-Demethylating; Substrate Specificity; Testosterone | 2000 |
Bactericidal and inhibitory effects of azole antifungal compounds on Mycobacterium smegmatis.
Topics: Antifungal Agents; Antitubercular Agents; Azoles; Clotrimazole; Econazole; Growth Inhibitors; Miconazole; Microbial Sensitivity Tests; Mycobacterium smegmatis; Triazoles | 2000 |
Econazole and miconazole inhibit steroidogenesis and disrupt steroidogenic acute regulatory (StAR) protein expression post-transcriptionally.
Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Antifungal Agents; Bucladesine; Cell Line; Cholesterol Side-Chain Cleavage Enzyme; Econazole; Gene Expression; Leydig Cells; Male; Mice; Miconazole; Phosphoproteins; Progesterone; Protein Biosynthesis; RNA Processing, Post-Transcriptional; RNA, Messenger; Steroids | 2000 |
Comparison of in vitro activities of amphotericin, clotrimazole, econazole, miconazole, and nystatin against Fusarium oxysporum.
Topics: Amphotericin B; Antifungal Agents; Clotrimazole; Cucurbitaceae; Econazole; Fusarium; Kinetics; Miconazole; Microbial Sensitivity Tests; Nystatin; Spores, Fungal | 2001 |
Comparison of the chiral resolution of econazole, miconazole, and sulconazole by HPLC using normal-phase amylose CSPs.
Topics: Amylose; Antifungal Agents; Chromatography, High Pressure Liquid; Econazole; Imidazoles; Miconazole; Molecular Conformation | 2001 |
Comparative study of the enantiomeric resolution of chiral antifungal drugs econazole, miconazole and sulconazole by HPLC on various cellulose chiral columns in normal phase mode.
Topics: Antifungal Agents; Cellulose; Chromatography, High Pressure Liquid; Econazole; Imidazoles; Miconazole; Stereoisomerism | 2002 |
[The problem of otomycosis treatment].
Topics: Adult; Aged; Antifungal Agents; Capsules; Clotrimazole; Ear Diseases; Econazole; Female; Humans; In Vitro Techniques; Itraconazole; Miconazole; Middle Aged; Ointments; Pulse Therapy, Drug | 2003 |
Strategy for the development of automated methods involving dialysis and trace enrichment as on-line sample preparation for the determination of basic drugs in plasma by liquid chromatography.
Topics: Antifungal Agents; Automation; Chromatography, Liquid; Clotrimazole; Dialysis; Econazole; Humans; Hydrogen-Ion Concentration; Indicators and Reagents; Miconazole; Solutions | 2002 |
Effects of cytochrome P450 inhibitors on agonist-induced Ca2+ responses and production of NO and PGI2 in vascular endothelial cells.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Antifungal Agents; Bradykinin; Calcium; Cyclic GMP; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug; Econazole; Endothelial Cells; Endothelium, Vascular; Enzyme Inhibitors; Epoprostenol; Miconazole; Nitric Oxide; Proadifen; Prostaglandins I; Signal Transduction; Swine; Thapsigargin; Time Factors | 2003 |
Experimental evaluation of antifungal and antiseptic agents against Rhodotorula spp.
Topics: Amphotericin B; Anti-Infective Agents, Local; Antifungal Agents; Drug Resistance, Fungal; Econazole; Fluconazole; Flucytosine; Humans; Itraconazole; Ketoconazole; Miconazole; Microbial Sensitivity Tests; Nystatin; Rhodotorula | 2003 |
In vitro antifungal activity of sertaconazole compared with nine other drugs against 250 clinical isolates of dermatophytes and Scopulariopsis brevicaulis.
Topics: Antifungal Agents; Arthrodermataceae; Ascomycota; Clotrimazole; Econazole; Fluconazole; Imidazoles; Itraconazole; Ketoconazole; Miconazole; Microbial Sensitivity Tests; Mitosporic Fungi; Naphthalenes; Terbinafine; Thiophenes | 2004 |
Usage of antifungal drugs for therapy of genital Candida infections, purchased as over-the-counter products or by prescription: I. Analyses of a unique database.
Topics: Adolescent; Adult; Antifungal Agents; Candidiasis, Vulvovaginal; Clotrimazole; Databases as Topic; Drug Prescriptions; Econazole; Female; Humans; Miconazole; Middle Aged; Nonprescription Drugs; Pharmacies; Recurrence; Self Medication; Sweden | 2004 |
Effects of Ca2+ channel blockers on store-operated Ca2+ channel currents of Kupffer cells after hepatic ischemia/reperfusion injury in rats.
Topics: Animals; Boron Compounds; Calcium Channel Blockers; Calcium Channels; Cell Survival; Dose-Response Relationship, Drug; Econazole; Imidazoles; Kupffer Cells; Liver; Male; Miconazole; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2006 |
Enantioselective separation of azole compounds by EKC. Reversal of migration order of enantiomers with CD concentration.
Topics: Azoles; beta-Cyclodextrins; Chromatography, Micellar Electrokinetic Capillary; Econazole; Imidazoles; Miconazole; Stereoisomerism | 2007 |
Screening of antimycotics in Swedish sewage treatment plants--waters and sludge.
Topics: Antifungal Agents; Clotrimazole; Econazole; Environmental Monitoring; Fluconazole; Ketoconazole; Miconazole; Naphthalenes; Sewage; Sweden; Terbinafine; Waste Disposal, Fluid; Water Pollutants, Chemical | 2010 |
Expression and characterization of Mycobacterium tuberculosis CYP144: common themes and lessons learned in the M. tuberculosis P450 enzyme family.
Topics: Anti-Infective Agents, Local; Bacterial Proteins; Binding, Competitive; Cell Division; Clotrimazole; Cytochrome P-450 Enzyme System; Econazole; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Gene Knockout Techniques; Kinetics; Miconazole; Mutation; Mycobacterium tuberculosis; Oxidation-Reduction; Potentiometry; Protein Binding; Recombinant Proteins; Spectrophotometry; Spectrum Analysis, Raman; Time Factors | 2011 |
Azole binding properties of Candida albicans sterol 14-alpha demethylase (CaCYP51).
Topics: Antifungal Agents; Azoles; Candida albicans; Econazole; Fluconazole; Itraconazole; Ketoconazole; Miconazole; Protein Binding; Pyrimidines; Sterol 14-Demethylase; Triazoles; Voriconazole | 2010 |
Whole-cell biotransformation assay for investigation of the human drug metabolizing enzyme CYP3A7.
Topics: Aryl Hydrocarbon Hydroxylases; Benzenesulfonates; Biocatalysis; Biotransformation; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Econazole; Firefly Luciferin; Gas Chromatography-Mass Spectrometry; Humans; Isoenzymes; Liver; Mass Spectrometry; Miconazole; Niacinamide; Pharmaceutical Preparations; Phenylurea Compounds; Polymorphism, Genetic; Pyridines; Schizosaccharomyces; Sorafenib; Testosterone | 2011 |
Chemical inhibitors of the calcium entry channel TRPV6.
Topics: Animals; Breast Neoplasms; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Proliferation; Cells, Cultured; Econazole; Female; Humans; Inhibitory Concentration 50; Male; Miconazole; Prostatic Neoplasms; Pyrrolidines; RNA, Small Interfering; TRPV Cation Channels | 2011 |
Asymmetric chemoenzymatic synthesis of miconazole and econazole enantiomers. The importance of chirality in their biological evaluation.
Topics: Animals; Antifungal Agents; Candida; Econazole; Humans; Hydrocarbons, Chlorinated; Lipase; Magnetic Resonance Spectroscopy; Miconazole; Microbial Sensitivity Tests; Molecular Structure; Stereoisomerism | 2011 |
Distribution, behavior and fate of azole antifungals during mechanical, biological, and chemical treatments in sewage treatment plants in China.
Topics: Antifungal Agents; Azoles; Biodegradation, Environmental; China; Clotrimazole; Econazole; Environmental Monitoring; Fluconazole; Ketoconazole; Miconazole; Sewage; Waste Disposal, Fluid; Water Pollutants, Chemical | 2012 |
Evaluation of chitosan based vaginal bioadhesive gel formulations for antifungal drugs.
Topics: Adhesiveness; Animals; Antifungal Agents; Chemistry, Pharmaceutical; Chitosan; Econazole; Female; Miconazole; Rats; Rats, Wistar; Rheology; Vaginal Creams, Foams, and Jellies; Viscosity | 2014 |
Antifungal efficiency of miconazole and econazole and the interaction with transport protein: a comparative study.
Topics: Antifungal Agents; Candida albicans; Carrier Proteins; Dose-Response Relationship, Drug; Econazole; Humans; Miconazole; Microscopy, Electron, Transmission; Molecular Docking Simulation; Protein Binding; Serum Albumin; Spectrometry, Fluorescence | 2015 |
Capillary electrophoretic enantioseparation of basic drugs using a new single-isomer cyclodextrin derivative and theoretical study of the chiral recognition mechanism.
Topics: Brompheniramine; Carbazoles; Carvedilol; Chlorpheniramine; Clenbuterol; Cyclodextrins; Econazole; Electrophoresis, Capillary; Isoproterenol; Miconazole; Molecular Structure; Pheniramine; Procaterol; Propanolamines; Stereoisomerism; Terbutaline; Tropanes | 2016 |
Evaluation of combination therapy for Burkholderia cenocepacia lung infection in different in vitro and in vivo models.
Topics: A549 Cells; Animals; Biofilms; Burkholderia cenocepacia; Burkholderia Infections; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Therapy, Combination; Econazole; Female; Humans; Mice; Mice, Inbred BALB C; Miconazole; Pneumonia, Bacterial; Tobramycin | 2017 |
Microwave-assisted microemulsion technique for production of miconazole nitrate- and econazole nitrate-loaded solid lipid nanoparticles.
Topics: A549 Cells; Antifungal Agents; Candida albicans; Cell Survival; Drug Compounding; Econazole; Emulsions; Humans; Lipids; Miconazole; Microwaves; Nanoparticles; X-Ray Diffraction | 2017 |
Sertaconazole induced toxicity in HeLa cells through mitotic arrest and inhibition of microtubule assembly.
Topics: A549 Cells; Animals; Antineoplastic Agents; Apoptosis; Cell Movement; Cell Proliferation; Drug Synergism; Econazole; Goats; HEK293 Cells; HeLa Cells; Humans; Imidazoles; Inhibitory Concentration 50; Miconazole; Microtubules; Mitosis; Thiophenes; Tubulin; Vinblastine | 2021 |
In vitro activity of 23 antifungal drugs against 54 clinical and environmental Aspergillus oryzae isolates.
Topics: Amphotericin B; Anidulafungin; Antifungal Agents; Aspergillus oryzae; Clotrimazole; Econazole; Fluconazole; Griseofulvin; Humans; Itraconazole; Ketoconazole; Miconazole; Microbial Sensitivity Tests; Natamycin; Nystatin; Terbinafine; Tolnaftate; Voriconazole | 2022 |
The structure and characterization of human cytochrome P450 8B1 supports future drug design for nonalcoholic fatty liver disease and diabetes.
Topics: Azoles; Bile Acids and Salts; Cholesterol; Cholic Acids; Cytochrome P-450 Enzyme System; Diabetes Mellitus, Type 2; Drug Design; Econazole; Heme; Humans; Iron; Miconazole; Nitrogen; Non-alcoholic Fatty Liver Disease; Steroid 12-alpha-Hydroxylase | 2022 |