econazole and clotrimazole

econazole has been researched along with clotrimazole in 119 studies

Research

Studies (119)

TimeframeStudies, this research(%)All Research%
pre-199049 (41.18)18.7374
1990's18 (15.13)18.2507
2000's30 (25.21)29.6817
2010's19 (15.97)24.3611
2020's3 (2.52)2.80

Authors

AuthorsStudies
Kawamura, Y; Kida, S; Matsumoto, H; Ogata, M; Shimizu, S; Tawara, K1
Brodie, AM; Clement, OO; Freeman, CM; Handratta, VD; Hartmann, RW; Njar, VC; Vasaitis, TS1
Doman, TN; McGovern, SL; Seidler, J; Shoichet, BK1
Hill, K; McNulty, S; Randall, AD1
Brien, JF; Dercho, RA; Kinobe, RT; Nakatsu, K; Szarek, WA; Vlahakis, JZ1
Ekins, S; Harwood, HJ; Hoover, DJ; Lawton, MP; Mankowski, DC; Treadway, JL1
Kelly, DE; Kelly, SL; Manning, NJ; Merkamm, M; Parker, JE; Pompon, D1
Jackson, CJ; Kelly, DE; Kelly, SL; Lamb, DC; Marczylo, TH; Parker, JE; Warrilow, AG1
Pratim Roy, P; Roy, K1
Botta, M; Castagnolo, D; De Logu, A; Dessì, F; Manetti, F; Meleddu, R; Radi, M; Saddi, M1
Bergès, T; Bouchara, JP; Chabasse, D; Renier, G; Rocher, F; Tronchin, G; Vandeputte, P1
de Montellano, PR; Ouellet, H; Podust, LM; von Kries, JP1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
DeGraw, AJ; Distefano, MD; Keiser, MJ; Ochocki, JD; Shoichet, BK1
Driscoll, MD; Lafite, P; Levy, C; Leys, D; Mast, N; McLean, KJ; Munro, AW; Pikuleva, IA; Rigby, SE1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Bakmiwewa, SM; Ball, HJ; Fatokun, AA; Hunt, NH; Payne, RJ; Tran, A1
Bartlett, SJ; Bauche, A; Fliegert, R; Guse, AH; Harneit, A; Kirchberger, T; Moreau, C; Potter, BV; Swarbrick, JM; Yorgan, T1
Aleo, MD; Bonin, PD; Luo, Y; Potter, DM; Swiss, R; Will, Y1
Balogh, I; Kim, HY; Koczok, K; Korade, Z; Liu, W; Mirnics, K; Porter, NA; Tallman, KA; Xu, L1
Abell, C; Chan, DS; Coyne, AG; de Carvalho, LP; Hudson, SA; James, GG; Kavanagh, ME; Levy, CW; Leys, D; Marino, LB; McLean, KJ; Munro, AW; Surade, S1
Azimi, I; Denny, WA; Flanagan, JU; Inserra, M; Monteith, GR; Stevenson, RJ; Vetter, I1
Emami, S; Keighobadi, M; Tavangar, P1
Sun, B; Sun, N; Sun, Y; Tian, L; Zhao, D; Zhao, L; Zhao, S1
Jin, H; Jin, Z; Lin, H; Liu, Z; Xu, Q; Yang, W; Yu, P; Zhang, H; Zhang, L; Zhang, Y; Zhao, S1
Bernander, S; Faergemann, J1
Drouhet, E1
Dupont, B; Lapresle, C1
Plempel, M1
Chen, XS; Jiang, YY; Long, K; Zhang, B1
Bellotti, MG; Dubini, F; Pestellini, V; Riviera, L1
Van Cutsem, J1
Kinghorn, GR; Robinson, AJ; Spencer, RS; Wilson, JD1
Abarca, L; Bragulat, M; Bruguera, T; Cabañes, FJ1
Frosch, PJ; Raulin, C1
Bastide, JM; Bastide, M; Jouvert, S; Lebecq, JC; Mallie, M; Montes, B1
Kalter, DC; McBride, ME; Wolf, JE1
Bossano, A; Cervetti, O; Forte, M; Pezzarossa, E1
Bothe, C; Reinel, D; Riemann, U; Senff, H1
Gschwind, C; Krause, U; Pavić, N1
Glasser, A1
Dix, BA; Freudenberger, J; Funke, PT; Georgopapadakou, NH; Smith, SA1
Bellotti, MG; Fantò, N; Giannotti, D; Giolitti, A; Pestellini, V; Riviera, L1
Meingassner, JG; Mieth, H; Petranyi, G1
Bassiouny, A; Hindawy, DS; Kamel, T; Moawad, MK1
Bellotti, MG; Riviera, L1
De Bernardis, F; Lorenzini, R; Mercantini, R1
Davies, RR; Zaini, F1
Cohen, L1
Abbott, AB; Odds, FC; Webster, CE1
Döring, HF; Ilgner, M1
Awouters, F; Janssen, PA; Levron, JC; Niemegeers, CJ1
Bastide, JM; Bastide, M; Jouvert, S2
Qadripur, SA1
Ditrich, O; Otcenásek, M1
Gorman, SP; Scott, EM; Wright, LR1
Gabriel, G; Thin, RN1
van der Stel, JJ; Voogd, CE1
Harada, S; Kusunoki, T2
Benijts, G; Kreysing, W; Stettendorf, S; Vignali, M1
Kawai, K; Nozawa, Y; Shiojiri, H; Watanabe, R1
Henderson, JT; Jevons, S; O'Neill East, M1
Dennerstein, GJ; Langley, R1
Krause, U; Qadripur, SA1
Högl, F; Raab, W1
Kamalam, A; Thambiah, AS1
Beutler, HK1
Haass, R; Werk, R1
Clayton, YM; Oji, EO1
Keuser, HR1
Binder, GL; Brown, D; Gardner, HL; Wells, J1
Meyer-Rohn, J; Puschmann, M1
Cazaux, M; Lepargneur, JP; Linas, MD; Riser, A; Saveres, C; Seguela, JP1
Benijts, G; Kreysing, W; Stettendorf, S; Vignalli, M1
Bogle, RG; Johnstone, AP; Soo, SC; Vallance, P; Whitley, GS1
Berry, M; Easty, DL; Gurung, A1
Perera, J; Seneviratne, HR1
Ekokoski, E; Forss, L; Törnquist, K1
Aussel, C; Bernard, A; Berthe, P; Breittmayer, JP; Cousin, JL1
Hegemann, L; Lahijani, KI; Toso, SM; Uitto, J; Webster, GF1
Aussel, C; Breittmayer, JP1
Friedman, FK; Hornstein, EH; Thomas, DE; Tsokos, GC; Vassilopoulos, D1
Andrisano, V; Cavrini, V; Di Pietra, AM; Gotti, R1
Harada, Y; Kiyohara, T; Miyata, S; Nakashima, T1
Drews, G; Welker, S1
Benkó, I; Hernádi, F; Kovács, P; Megyeri, A1
Helmeste, DM; Tang, SW; Vu, R1
Benko, I; Hernádi, F; Kiss, A; Kovács, P; Kraicsovits, F; Megyeri, A; Somogyi, G; Tegyey, Z1
Bouchara, JP; Chabasse, D; Declerk, P; Defontaine, A; Hallet, JN; Planchenault, C1
Assmann, G; Junker, R; Nofer, JR; Seedorf, U; Tepel, M; Walter, M; Zidek, W1
Fowler, SM; Friedberg, T; Pritchard, MP; Riley, RJ; Sutcliffe, MJ; Wolf, CR1
Fauler, G; Köfeler, HC; Leis, HJ; Windischhofer, W1
Jackson, CJ; Kelly, DE; Kelly, SL; Lamb, DC1
Charvalos, E; Tsatsakis, AM; Tzatzarakis, MN; Vakalounakis, D1
Lima, SM; Martins, RS; Mesquita, RA; Péreira, ES; Santos, VR; Senna, MI1
Engelen, M; Rochette, F; Vanden Bossche, H1
Kurdina, MI1
Chiap, P; Crommen, J; Hubert, P1
Carrillo-Muñoz, AJ; Casals, J; del Valle, O; Guardià, C; Guglietta, A; Palacín, C; Quindós, G; Rodríguez, V1
Holmén, J; Landgren, M; Mårdh, PA; Wågström, J1
Besra, GS; Burguière, A; Dell, A; Dover, LG; Hitchen, PG1
Ahmad, Z; Khuller, GK; Pandey, R; Sharma, S1
Fonfria, E; McNulty, S1
Ahmad, Z; Khuller, GK; Sharma, S2
Crawford, F2
de Montellano, PR; Ouellet, H; Podust, LM1
Fick, J; Lindberg, RH; Tysklind, M1
Klemm, E; Vennewald, I1
Carroll, P; Cheesman, MR; Driscoll, MD; Howard, M; Jowitt, TA; McLean, KJ; Munro, AW; Parish, T1
Kang, NS; Kang, YK; Lee, JY1
Huang, Q; Peng, X; Wang, C; Wang, Z; Yu, Y; Zhang, K1
Borborema, SE; da Costa-Silva, TA; Mesquita, JT; Tempone, AG1
Dai, H; Li, Y; Qiu, W; Ren, B; Zhang, L; Zhang, Q; Zhou, X1
Ahmed, MB; Ahmed, S; Alam, MM; Islam, MR; Khan, L; Mostafa, MG; Rahman, MA1
Abastabar, M; Aghili, SR; Badali, H; Haghani, I; Hedayati, MT; Javidnia, J; Khojasteh, S; Meis, JF; Moazeni, M; Nargesi, S; Nosratabadi, M; Shabanzadeh, S; Shokohi, T; Zaedi, A1

Reviews

8 review(s) available for econazole and clotrimazole

ArticleYear
An overview of azoles targeting sterol 14α-demethylase for antileishmanial therapy.
    European journal of medicinal chemistry, 2017, Jul-28, Volume: 135

    Topics: 14-alpha Demethylase Inhibitors; Antiprotozoal Agents; Azoles; Humans; Leishmania; Molecular Structure; Sterol 14-Demethylase

2017
Strategies for the development of highly selective cytochrome P450 inhibitors: Several CYP targets in current research.
    Bioorganic & medicinal chemistry letters, 2019, 08-15, Volume: 29, Issue:16

    Topics: Animals; Binding Sites; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Development; Heme; Humans; Hydrophobic and Hydrophilic Interactions; Protein Binding

2019
Antifungal agents.
    Antibiotics and chemotherapy, 1978, Volume: 25

    Topics: Amphotericin B; Antifungal Agents; Clotrimazole; Econazole; Flucytosine; Griseofulvin; Humans; Imidazoles; Intestinal Absorption; Miconazole; Nystatin; Peptides; Polyenes

1978
Antifungal agents of use in animal health--chemical, biochemical and pharmacological aspects.
    Journal of veterinary pharmacology and therapeutics, 2003, Volume: 26, Issue:1

    Topics: Animals; Antifungal Agents; Clotrimazole; Drug Resistance, Fungal; Econazole; Fluconazole; Flucytosine; Griseofulvin; Imidazoles; Itraconazole; Ketoconazole; Miconazole; Naphthalenes; Natamycin; Nystatin; Terbinafine; Thiabendazole; Tolnaftate; Veterinary Drugs

2003
The role of TRPM channels in cell death.
    Pflugers Archiv : European journal of physiology, 2005, Volume: 451, Issue:1

    Topics: Animals; Cell Death; Clotrimazole; Econazole; Flufenamic Acid; Gene Expression Profiling; Humans; Neurodegenerative Diseases; Oligoribonucleotides, Antisense; Oxidative Stress; Protein Serine-Threonine Kinases; Rats; RNA Interference; TRPM Cation Channels

2005
Athlete's foot.
    Clinical evidence, 2005, Issue:14

    Topics: Allylamine; Antifungal Agents; Clotrimazole; Econazole; Humans; Imidazoles; Miconazole; Naphthalenes; Terbinafine; Tinea Pedis

2005
Otomycosis: Diagnosis and treatment.
    Clinics in dermatology, 2010, Mar-04, Volume: 28, Issue:2

    Topics: Administration, Topical; Amphotericin B; Anti-Infective Agents; Antifungal Agents; Clotrimazole; Drug Resistance, Fungal; Econazole; Humans; Itraconazole; Miconazole; Mycoses; Ointments; Otitis Externa

2010
Athlete's foot.
    BMJ clinical evidence, 2009, Jul-20, Volume: 2009

    Topics: Administration, Oral; Administration, Topical; Clotrimazole; Drug Administration Schedule; Econazole; Evidence-Based Medicine; Humans; Hygiene; Miconazole; Tinea Pedis

2009

Trials

14 trial(s) available for econazole and clotrimazole

ArticleYear
[One-day trial therapy with 500 mg clotrimazole vaginal tablets and 150 mg econazole nitrate-depot ovules in vaginal mycoses: results of an open comparative study].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1988, Apr-12, Volume: 77, Issue:15

    Topics: Administration, Intravaginal; Adult; Candidiasis, Vulvovaginal; Clotrimazole; Delayed-Action Preparations; Drug Evaluation; Econazole; Female; Humans; Imidazoles; Middle Aged

1988
[Single dose therapy of vaginal mycoses. Effectiveness of clotrimazole and econazole].
    Fortschritte der Medizin, 1986, Mar-27, Volume: 104, Issue:12

    Topics: Adolescent; Adult; Clinical Trials as Topic; Clotrimazole; Drug Administration Schedule; Econazole; Female; Humans; Imidazoles; Middle Aged; Mycoses; Pregnancy; Random Allocation; Vaginitis

1986
Is more than one application of an antifungal necessary in the treatment of acute vaginal candidiasis?
    American journal of obstetrics and gynecology, 1985, Aug-01, Volume: 152, Issue:7 Pt 2

    Topics: Amphotericin B; Antifungal Agents; Candidiasis, Vulvovaginal; Clinical Trials as Topic; Clotrimazole; Double-Blind Method; Drug Administration Schedule; Econazole; Female; Follow-Up Studies; Humans; Imidazoles; Miconazole; Nystatin; Pessaries; Recurrence; Vaginal Creams, Foams, and Jellies; Wales

1985
Clotrimazole and econazole in the treatment of vaginal candidosis. A single-blind comparison.
    The British journal of venereal diseases, 1983, Volume: 59, Issue:1

    Topics: Candidiasis, Vulvovaginal; Clinical Trials as Topic; Clotrimazole; Econazole; Female; Humans; Imidazoles; Random Allocation

1983
Three-day therapy of vaginal candidiasis with clotrimazole vaginal tablets and econazole ovules: a multicenter comparative study.
    Chemotherapy, 1982, Volume: 28 Suppl 1

    Topics: Adolescent; Adult; Candidiasis, Vulvovaginal; Clinical Trials as Topic; Clotrimazole; Econazole; Female; Follow-Up Studies; Humans; Imidazoles; Middle Aged; Pregnancy; Random Allocation; Tablets

1982
Vulvovaginal candidiasis: treatment and recurrence.
    The Australian & New Zealand journal of obstetrics & gynaecology, 1982, Volume: 22, Issue:4

    Topics: Adolescent; Adult; Antifungal Agents; Candidiasis, Vulvovaginal; Child; Clotrimazole; Econazole; Female; Humans; Miconazole; Middle Aged; Nystatin; Recurrence; Vaginal Creams, Foams, and Jellies

1982
[Double blind trial of clotrimazole and econazole in tinea pedis (author's transl)].
    Mykosen, 1980, Volume: 23, Issue:1

    Topics: Adolescent; Adult; Aged; Child; Clinical Trials as Topic; Clotrimazole; Double-Blind Method; Econazole; Female; Humans; Imidazoles; Male; Middle Aged; Ointments; Tinea Pedis

1980
Clotrimazole and econazole in dermatophytoses (double blind study).
    Mykosen, 1980, Volume: 23, Issue:12

    Topics: Adolescent; Adult; Child; Child, Preschool; Clinical Trials as Topic; Clotrimazole; Double-Blind Method; Econazole; Female; Humans; Imidazoles; Infant; Male; Ointments; Tinea

1980
[Treatment of vaginal mycosis - comparison of clotrimazole and econazole in a clinical trial within a 3-day-therapy (author's transl)].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1981, Jul-21, Volume: 70, Issue:30

    Topics: Adult; Clinical Trials as Topic; Clotrimazole; Econazole; Female; Humans; Imidazoles; Mycoses; Vaginitis

1981
[Treatment of vaginal yeast infections. 2% Clotrimazole vaginal cream in 3-day therapy and 1% econazolenitrate vaginal cream in 7-day therapy; clinical comparison].
    Fortschritte der Medizin, 1981, Jul-23, Volume: 99, Issue:27-28

    Topics: Clotrimazole; Dose-Response Relationship, Drug; Drug Administration Schedule; Econazole; Female; Humans; Imidazoles; Mycoses; Vaginitis

1981
Comparison of econazole and clotrimazole in the treatment of vulvovaginal candidiasis.
    Obstetrics and gynecology, 1980, Volume: 56, Issue:1

    Topics: Adolescent; Adult; Candidiasis, Vulvovaginal; Clotrimazole; Econazole; Female; Humans; Imidazoles; Middle Aged; Time Factors

1980
Three-day therapy of vaginal candidiasis with clotrimazole vaginal tablets and econazole ovules: a multicentre comparative study.
    Current medical research and opinion, 1980, Volume: 7, Issue:1

    Topics: Adolescent; Adult; Aged; Candidiasis, Vulvovaginal; Clotrimazole; Econazole; Female; Humans; Imidazoles; Middle Aged; Suppositories; Tablets; Vagina

1980
Econazole and clotrimazole in the treatment of vaginal candidiasis: a double blind comparative study.
    The Ceylon medical journal, 1994, Volume: 39, Issue:3

    Topics: Adolescent; Adult; Aged; Candidiasis, Vulvovaginal; Clotrimazole; Double-Blind Method; Econazole; Female; Humans; Middle Aged

1994
Efficacy of Clotrimazole 1% Solution Compared to Econazole Nitrate 1% + Triamcinolone Acetonide 0.1% Cream in Patient with Otomycosis.
    Mymensingh medical journal : MMJ, 2021, Volume: 30, Issue:3

    Topics: Administration, Topical; Antifungal Agents; Bangladesh; Clotrimazole; Econazole; Humans; Otomycosis; Triamcinolone Acetonide

2021

Other Studies

97 other study(ies) available for econazole and clotrimazole

ArticleYear
Synthesis and antifungal activity of a series of novel 1,2-disubstituted propenones.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:8

    Topics: Animals; Aspergillus fumigatus; Candida albicans; Candidiasis; Chemical Phenomena; Chemistry; Fungi; Ketones; Mice; Propiophenones; Structure-Activity Relationship; Trichophyton

1987
Three dimensional pharmacophore modeling of human CYP17 inhibitors. Potential agents for prostate cancer therapy.
    Journal of medicinal chemistry, 2003, Jun-05, Volume: 46, Issue:12

    Topics: Algorithms; Antineoplastic Agents; Azoles; Binding Sites; Enzyme Inhibitors; Humans; Hydrogen Bonding; Male; Models, Molecular; Prostatic Neoplasms; Protein Binding; Quantitative Structure-Activity Relationship; Steroid 17-alpha-Hydroxylase; Steroids

2003
Identification and prediction of promiscuous aggregating inhibitors among known drugs.
    Journal of medicinal chemistry, 2003, Oct-09, Volume: 46, Issue:21

    Topics: Antifungal Agents; beta-Lactamase Inhibitors; Chemical Phenomena; Chemistry, Physical; Chymotrypsin; Enzyme Inhibitors; Kinetics; Light; Malate Dehydrogenase; Models, Molecular; Molecular Conformation; Scattering, Radiation; Structure-Activity Relationship

2003
Inhibition of TRPM2 channels by the antifungal agents clotrimazole and econazole.
    Naunyn-Schmiedeberg's archives of pharmacology, 2004, Volume: 370, Issue:4

    Topics: Animals; Antifungal Agents; Cell Line; Clotrimazole; Dose-Response Relationship, Drug; Econazole; Humans; Ion Channels; Membrane Proteins; Rats; TRPM Cation Channels

2004
Inhibition of the enzymatic activity of heme oxygenases by azole-based antifungal drugs.
    The Journal of pharmacology and experimental therapeutics, 2006, Volume: 319, Issue:1

    Topics: Animals; Antifungal Agents; Enzyme Inhibitors; Heme Oxygenase (Decyclizing); Ketoconazole; Kinetics; Male; Microsomes, Liver; Rats; Rats, Sprague-Dawley

2006
Three-dimensional quantitative structure-activity relationship analysis of human CYP51 inhibitors.
    Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:3

    Topics: Amides; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Humans; Indoles; Models, Molecular; Oxidoreductases; Quantitative Structure-Activity Relationship; Sterol 14-Demethylase

2007
Differential azole antifungal efficacies contrasted using a Saccharomyces cerevisiae strain humanized for sterol 14 alpha-demethylase at the homologous locus.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:10

    Topics: Antifungal Agents; Azoles; Base Sequence; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; DNA, Fungal; Drug Resistance, Fungal; Genes, Fungal; Humans; Molecular Sequence Data; Recombinant Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Species Specificity; Sterol 14-Demethylase

2008
Identification, characterization, and azole-binding properties of Mycobacterium smegmatis CYP164A2, a homolog of ML2088, the sole cytochrome P450 gene of Mycobacterium leprae.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:3

    Topics: Amino Acid Motifs; Amino Acid Sequence; Azoles; Base Sequence; Cloning, Molecular; Conserved Sequence; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Genes, Bacterial; Hydrogen-Ion Concentration; Molecular Sequence Data; Molecular Structure; Molecular Weight; Mycobacterium leprae; Mycobacterium smegmatis; Osmolar Concentration; Recombinant Proteins; Sequence Homology, Amino Acid; Sodium Chloride

2009
Comparative chemometric modeling of cytochrome 3A4 inhibitory activity of structurally diverse compounds using stepwise MLR, FA-MLR, PLS, GFA, G/PLS and ANN techniques.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:7

    Topics: Algorithms; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Enzyme Inhibitors; Factor Analysis, Statistical; Least-Squares Analysis; Linear Models; Models, Molecular; Neural Networks, Computer; Quantitative Structure-Activity Relationship; Reproducibility of Results

2009
Synthesis and biological evaluation of new enantiomerically pure azole derivatives as inhibitors of Mycobacterium tuberculosis.
    Bioorganic & medicinal chemistry letters, 2009, Apr-15, Volume: 19, Issue:8

    Topics: Antitubercular Agents; Azoles; Drug Evaluation, Preclinical; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Stereoisomerism

2009
Hypersusceptibility to azole antifungals in a clinical isolate of Candida glabrata with reduced aerobic growth.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:7

    Topics: Adult; Aerobiosis; Antifungal Agents; Azoles; Candida glabrata; Chromatography, High Pressure Liquid; Ergosterol; Female; Flow Cytometry; Genes, Fungal; Humans; Microbial Sensitivity Tests; Microscopy, Electron, Transmission; Molecular Sequence Data; Polyenes

2009
Interaction of Mycobacterium tuberculosis CYP130 with heterocyclic arylamines.
    The Journal of biological chemistry, 2009, Sep-11, Volume: 284, Issue:37

    Topics: Amines; Amino Acid Sequence; Bacterial Proteins; Catalysis; Catalytic Domain; Crystallography, X-Ray; Cytochrome P-450 Enzyme System; Gene Library; Ligands; Molecular Conformation; Molecular Sequence Data; Mycobacterium tuberculosis; Protein Binding; Sequence Homology, Amino Acid; Spectrophotometry

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Prediction and evaluation of protein farnesyltransferase inhibition by commercial drugs.
    Journal of medicinal chemistry, 2010, Mar-25, Volume: 53, Issue:6

    Topics: Animals; Cell Line; Dose-Response Relationship, Drug; Enzyme Inhibitors; Farnesyltranstransferase; Green Fluorescent Proteins; Histamine H1 Antagonists, Non-Sedating; Ligands; Loratadine; Miconazole; Microscopy, Confocal; Molecular Structure; Pharmaceutical Preparations; Protein Interaction Mapping; Protein Prenylation; ras Proteins; Recombinant Fusion Proteins; Technology, Pharmaceutical

2010
Structural and biochemical characterization of Mycobacterium tuberculosis CYP142: evidence for multiple cholesterol 27-hydroxylase activities in a human pathogen.
    The Journal of biological chemistry, 2010, Dec-03, Volume: 285, Issue:49

    Topics: Cholesterol; Crystallography, X-Ray; Cytochrome P-450 Enzyme System; Host-Pathogen Interactions; Humans; Hydroxylation; Mycobacterium tuberculosis; Oxidation-Reduction; Protein Structure, Tertiary

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Identification of selective inhibitors of indoleamine 2,3-dioxygenase 2.
    Bioorganic & medicinal chemistry letters, 2012, Dec-15, Volume: 22, Issue:24

    Topics: Animals; Dose-Response Relationship, Drug; Enzyme Inhibitors; HEK293 Cells; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Mice; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Substrate Specificity

2012
Structure-activity relationship of adenosine 5'-diphosphoribose at the transient receptor potential melastatin 2 (TRPM2) channel: rational design of antagonists.
    Journal of medicinal chemistry, 2013, Dec-27, Volume: 56, Issue:24

    Topics: Adenosine Diphosphate Ribose; Dose-Response Relationship, Drug; Drug Design; Humans; Models, Molecular; Molecular Structure; Structure-Activity Relationship; TRPM Cation Channels

2013
Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump.
    Hepatology (Baltimore, Md.), 2014, Volume: 60, Issue:3

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Chemical and Drug Induced Liver Injury; Humans; Male; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Severity of Illness Index

2014
The Effect of Small Molecules on Sterol Homeostasis: Measuring 7-Dehydrocholesterol in Dhcr7-Deficient Neuro2a Cells and Human Fibroblasts.
    Journal of medicinal chemistry, 2016, Feb-11, Volume: 59, Issue:3

    Topics: Animals; Cell Line; Dehydrocholesterols; Dose-Response Relationship, Drug; Fibroblasts; Homeostasis; Humans; Mice; Molecular Conformation; Neurons; Oxidoreductases Acting on CH-CH Group Donors; Small Molecule Libraries; Sterols; Structure-Activity Relationship

2016
Fragment-Based Approaches to the Development of Mycobacterium tuberculosis CYP121 Inhibitors.
    Journal of medicinal chemistry, 2016, Apr-14, Volume: 59, Issue:7

    Topics: Bacterial Proteins; Binding Sites; Crystallography, X-Ray; Cytochrome P-450 Enzyme System; Drug Design; Enzyme Inhibitors; Humans; Ligands; Mycobacterium tuberculosis; Protein Binding; Protein Structure, Tertiary; Tuberculosis

2016
Evaluation of known and novel inhibitors of Orai1-mediated store operated Ca
    Bioorganic & medicinal chemistry, 2017, 01-01, Volume: 25, Issue:1

    Topics: Calcium Channel Blockers; Cell Line, Tumor; Databases, Chemical; Drug Stability; Fluorescence; HEK293 Cells; High-Throughput Screening Assays; Humans; ORAI1 Protein; Stereoisomerism; Structure-Activity Relationship; Triazoles

2017
The Discovery of Novel ACA Derivatives as Specific TRPM2 Inhibitors that Reduce Ischemic Injury Both In Vitro and In Vivo.
    Journal of medicinal chemistry, 2021, 04-08, Volume: 64, Issue:7

    Topics: Animals; Cell Line, Tumor; Cinnamates; Glucose; HEK293 Cells; Humans; Infarction, Middle Cerebral Artery; Male; Mice, Inbred C57BL; Molecular Structure; Neuroprotective Agents; ortho-Aminobenzoates; Oxygen; Reperfusion Injury; Structure-Activity Relationship; TRPM Cation Channels

2021
The activity in vitro of five different antimycotics against Pityrosporum orbiculare.
    Acta dermato-venereologica, 1979, Volume: 59, Issue:6

    Topics: Antifungal Agents; Clotrimazole; Cyclic N-Oxides; Econazole; Malassezia; Miconazole; Microbial Sensitivity Tests; Pharmaceutical Vehicles; Pyridines; Solvents; Thiones; Thiosulfates

1979
[Recent progress in the treatment of systemic mycotic infections].
    Acquisitions medicales recentes, 1979

    Topics: Antifungal Agents; Clotrimazole; Econazole; Flucytosine; Humans; Miconazole; Mycoses

1979
Pharmacokinetics of imidazole antimycotics.
    Postgraduate medical journal, 1979, Volume: 55, Issue:647

    Topics: Adult; Animals; Antifungal Agents; Child; Clotrimazole; Econazole; Fungi; Guinea Pigs; Humans; Imidazoles; Kinetics; Mice; Miconazole; Rabbits; Time Factors

1979
[Effects of econazole and clotrimazole on TXB2 and PGE2 production in calcimycin-stimulated neutrophils and arachidonic acid-stimulated platelets].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1991, Volume: 12, Issue:3

    Topics: Animals; Blood Platelets; Clotrimazole; Dinoprostone; Econazole; Male; Neutrophils; Rabbits; Rats; Rats, Inbred Strains; Thromboxane B2

1991
Antifungal activity of two benzofuran-imidazoles in different experimental conditions.
    Journal of chemotherapy (Florence, Italy), 1991, Volume: 3, Issue:5

    Topics: Antifungal Agents; Arthrodermataceae; Candida; Candida albicans; Clotrimazole; Culture Media; Drug Resistance, Microbial; Econazole; Hydrogen-Ion Concentration; Imidazoles; Microbial Sensitivity Tests; Microsporum; Trichophyton

1991
The in vitro activity of terconazole against yeasts: its topical long-acting therapeutic efficacy in experimental vaginal candidiasis in rats.
    American journal of obstetrics and gynecology, 1991, Volume: 165, Issue:4 Pt 2

    Topics: Administration, Topical; Amphotericin B; Animals; Antifungal Agents; Candida; Candidiasis, Vulvovaginal; Clotrimazole; Econazole; Female; Miconazole; Microbial Sensitivity Tests; Nystatin; Rats; Rats, Inbred Strains; Triazoles

1991
Econazole nitrate (150 mg) single dose vaginal pessary compared with clotrimazole (10%) single dose vaginal cream to treat women with vaginal candidiasis.
    Genitourinary medicine, 1989, Volume: 65, Issue:3

    Topics: Candidiasis, Vulvovaginal; Clotrimazole; Drug Evaluation; Econazole; Female; Humans; Imidazoles; Pessaries; Vaginal Creams, Foams, and Jellies

1989
Sensitivity of some strains of the genus Epidermophyton to different antifungal agents.
    Mycopathologia, 1989, Volume: 105, Issue:3

    Topics: Antifungal Agents; Clotrimazole; Econazole; Epidermophyton; Griseofulvin; Imidazoles; Ketoconazole; Miconazole; Natamycin; Nystatin

1989
Contact allergy to imidazole antimycotics.
    Contact dermatitis, 1988, Volume: 18, Issue:2

    Topics: Adult; Aged; Antifungal Agents; Chemical Phenomena; Chemistry; Clotrimazole; Drug Eruptions; Econazole; Female; Humans; Imidazoles; Male; Miconazole; Middle Aged; Prospective Studies

1988
[Comparative action of 8 azole derivatives against Candida albicans: fungistatic action and cytologic study by scanning electron microscopy].
    Pathologie-biologie, 1988, Volume: 36, Issue:5

    Topics: Antifungal Agents; Candida albicans; Clotrimazole; Cytoplasm; Econazole; Imidazoles; Ketoconazole; Miconazole; Microbial Sensitivity Tests; Microscopy, Electron, Scanning; Spheroplasts; Triazoles

1988
Antifungal susceptibility testing of Trichosporon beigelii to imidazole compounds.
    Canadian journal of microbiology, 1988, Volume: 34, Issue:7

    Topics: Amphotericin B; Clotrimazole; Culture Media; Econazole; Genital Diseases, Male; Hair; Humans; Imidazoles; Ketoconazole; Male; Miconazole; Microbial Sensitivity Tests; Mitosporic Fungi; Mycoses; Piedra; Scrotum; Trichosporon

1988
[In vitro study on the validity of the use of antimycograms in the target treatment of superficial candidiasis].
    Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia, 1988, Volume: 123, Issue:6

    Topics: Adolescent; Adult; Aged; Antifungal Agents; Candida; Candidiasis, Cutaneous; Child; Ciclopirox; Clotrimazole; Econazole; Female; Humans; Imidazoles; Male; Miconazole; Middle Aged; Nystatin; Pyridones

1988
[Local therapy of pityriasis versicolor with 3 imidazole derivatives--results of a therapeutic study. Studies of the rate of recurrence].
    Zeitschrift fur Hautkrankheiten, 1988, Dec-15, Volume: 63, Issue:12

    Topics: Administration, Topical; Adult; Clotrimazole; Econazole; Follow-Up Studies; Humans; Imidazoles; Male; Miconazole; Recurrence; Tinea Versicolor

1988
Effect of antifungal agents on lipid biosynthesis and membrane integrity in Candida albicans.
    Antimicrobial agents and chemotherapy, 1987, Volume: 31, Issue:1

    Topics: Allylamine; Animals; Antifungal Agents; Candida albicans; Cell Membrane; Cerulenin; Cholestadienols; Chromatography, Gas; Chromatography, Thin Layer; Clotrimazole; Culture Techniques; Econazole; Ergosterol; Fatty Acids; Ketoconazole; Lipids; Miconazole; Tolnaftate

1987
New benzofuran-imidazoles as antimycotic agents. II. In vitro studies.
    Chemioterapia : international journal of the Mediterranean Society of Chemotherapy, 1987, Volume: 6, Issue:4

    Topics: Antifungal Agents; Arthrodermataceae; Benzofurans; Clotrimazole; Econazole; Fungi; Griseofulvin; Hydrogen-Ion Concentration; Imidazoles; Microbial Sensitivity Tests; Yeasts

1987
Antifungal activity of the allylamine derivative terbinafine in vitro.
    Antimicrobial agents and chemotherapy, 1987, Volume: 31, Issue:9

    Topics: Agar; Antifungal Agents; Arthrodermataceae; Candida; Clotrimazole; Econazole; Ketoconazole; Microbial Sensitivity Tests; Naphthalenes; Species Specificity; Terbinafine

1987
Broad spectrum antifungal agents in otomycosis.
    The Journal of laryngology and otology, 1986, Volume: 100, Issue:8

    Topics: Antifungal Agents; Ciclopirox; Clotrimazole; Ear Diseases; Econazole; Fungi; Humans; Miconazole; Microbial Sensitivity Tests; Mycoses; Pyridones

1986
Siccanin: a new antifungal antibiotic with antidermatophytic properties. In vitro studies.
    Chemioterapia : international journal of the Mediterranean Society of Chemotherapy, 1985, Volume: 4, Issue:6

    Topics: Arthrodermataceae; Candida; Clotrimazole; Econazole; Epidermophyton; Flucytosine; Griseofulvin; Microbial Sensitivity Tests; Microsporum; Trichophyton; Xanthenes

1985
In vitro sensitivity of Malassezia spp. to various antimycotics.
    Drugs under experimental and clinical research, 1985, Volume: 11, Issue:6

    Topics: Amphotericin B; Animals; Antifungal Agents; Clotrimazole; Dog Diseases; Dogs; Econazole; Humans; Ketoconazole; Malassezia; Miconazole; Microbial Sensitivity Tests; Nystatin; Otitis; Tinea Versicolor

1985
Antifungal drugs affecting the chemotaxis of polymorphonuclear neutrophils.
    Sabouraudia, 1985, Volume: 23, Issue:2

    Topics: Antifungal Agents; Cell Extracts; Chemotaxis, Leukocyte; Clotrimazole; Complement System Proteins; Econazole; Griseofulvin; Humans; Ketoconazole; Miconazole; Natamycin; Neutrophils; Trichophyton

1985
Antifungal relative inhibition factors: BAY l-9139, bifonazole, butoconazole, isoconazole, itraconazole (R 51211), oxiconazole, Ro 14-4767/002, sulconazole, terconazole and vibunazole (BAY n-7133) compared in vitro with nine established antifungal agents.
    The Journal of antimicrobial chemotherapy, 1984, Volume: 14, Issue:2

    Topics: Antifungal Agents; Aspergillus; Candida; Clotrimazole; Econazole; Imidazoles; In Vitro Techniques; Itraconazole; Ketoconazole; Miconazole; Morpholines; Triazoles

1984
[Local treatment of rosacea with imidazole derivatives].
    Zeitschrift fur Hautkrankheiten, 1983, Feb-01, Volume: 58, Issue:3

    Topics: Administration, Topical; Adult; Aged; Clotrimazole; Econazole; Female; Humans; Imidazoles; Male; Metronidazole; Miconazole; Middle Aged; Rosacea

1983
Inhibition and induction of microsomal enzymes in rat. A comparative study of four antimycotics: miconazole, econazole, clotrimazole and ketoconazole.
    Archives internationales de pharmacodynamie et de therapie, 1981, Volume: 251, Issue:1

    Topics: Animals; Antifungal Agents; Clotrimazole; Econazole; Enzyme Induction; Enzyme Inhibitors; Imidazoles; Ketoconazole; Male; Miconazole; Microsomes, Liver; Pharmaceutical Preparations; Piperazines; Rats

1981
A comparison of the effects of several antifungal imidazole derivatives and polyenes on Candida albicans: an ultrastructural study by scanning electron microscopy.
    Canadian journal of microbiology, 1982, Volume: 28, Issue:10

    Topics: Amphotericin B; Antifungal Agents; Candida albicans; Cell Membrane; Cell Wall; Clotrimazole; Econazole; Imidazoles; Ketoconazole; Miconazole; Microscopy, Electron, Scanning; Nystatin; Piperazines

1982
[Antimycotic therapy. 2. Antimycotic chemotherapeutic agents: imidazole derivatives, tolciclate, haloprogin, ciclopiroxolamin].
    Fortschritte der Medizin, 1983, Mar-10, Volume: 101, Issue:9

    Topics: Antifungal Agents; Chemical Phenomena; Chemistry; Ciclopirox; Clotrimazole; Dermatomycoses; Econazole; Humans; Imidazoles; Ketoconazole; Miconazole; Phenyl Ethers; Piperazines; Pyridones; Thiocarbamates

1983
Comparative susceptibility of the agents of adiaspiromycosis to imidazole derivatives in vitro.
    Sabouraudia, 1983, Volume: 21, Issue:3

    Topics: Antifungal Agents; Chrysosporium; Clotrimazole; Econazole; Imidazoles; Ketoconazole; Miconazole; Mitosporic Fungi; Spores, Fungal

1983
The effect of imidazoles on germination of arthrospores and microconidia of Trichophyton mentagrophytes.
    The Journal of antimicrobial chemotherapy, 1984, Volume: 13, Issue:2

    Topics: Clotrimazole; Econazole; Imidazoles; Ketoconazole; Miconazole; Microbial Sensitivity Tests; Spores, Fungal; Trichophyton

1984
Are econazole, miconazole and clotrimazole mutagenic to bacteria?
    Mutation research, 1983, Volume: 120, Issue:2-3

    Topics: Bacteria; Clotrimazole; Econazole; Escherichia coli; Imidazoles; Klebsiella pneumoniae; Miconazole; Microbial Sensitivity Tests; Mutagenicity Tests; Mutation; Salmonella typhimurium

1983
Comparison of the in vitro antifungal activities of clotrimazole, miconazole, econazole and exalamide against clinical isolates of dermatophytes.
    The Journal of dermatology, 1984, Volume: 11, Issue:3

    Topics: Antifungal Agents; Arthrodermataceae; Benzamides; Clotrimazole; Econazole; Humans; In Vitro Techniques; Miconazole

1984
Chlorination-induced enhancement of biological activities in imidazole antimycotics. A possible explanation to the molecular mechanism for their antimycotic activities.
    Research communications in chemical pathology and pharmacology, 1983, Volume: 40, Issue:2

    Topics: Animals; Antifungal Agents; Chemical Phenomena; Chemistry; Chlorine; Clotrimazole; Econazole; Imidazoles; In Vitro Techniques; Miconazole; Mitochondria, Liver; Mitochondrial Swelling; Oxidative Phosphorylation; Rats; Structure-Activity Relationship

1983
Tioconazole in the treatment of fungal infections of the skin. An international clinical research program.
    Dermatologica, 1983, Volume: 166 Suppl 1

    Topics: Adolescent; Antifungal Agents; Clotrimazole; Dermatomycoses; Drug Evaluation; Econazole; Erythrasma; Female; Humans; Imidazoles; Male; Miconazole; Pharmaceutical Vehicles; Tinea

1983
[Comparison of the in vitro antifungal activities of clotrimazole, miconazole, Econazole and exalamide against clinical isolates of dermatophytes (author's transl)].
    Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology, 1982, Volume: 92, Issue:6

    Topics: Antifungal Agents; Arthrodermataceae; Benzamides; Clotrimazole; Econazole; Humans; Imidazoles; Miconazole

1982
[Effect of imidazole derivatives on various numbers of microbes to determine microbial sensitivity].
    Zeitschrift fur Hautkrankheiten, 1980, Sep-01, Volume: 55, Issue:17

    Topics: Candida albicans; Clotrimazole; Econazole; Imidazoles; Microbial Sensitivity Tests; Saccharomyces cerevisiae; Staphylococcus aureus

1980
[The antimycotica disc elution test: a new quantitative antimycotica test for yeasts (author's transl)].
    Immunitat und Infektion, 1982, Volume: 10, Issue:3

    Topics: Antifungal Agents; Candida albicans; Clotrimazole; Econazole; Flucytosine; Miconazole; Microbial Sensitivity Tests

1982
[Cytological study of the action of imidazoles on Candida albicans (author's transl)].
    Pathologie-biologie, 1982, Volume: 30, Issue:6

    Topics: Antifungal Agents; Candida albicans; Cell Membrane; Cell Wall; Clotrimazole; Econazole; Imidazoles; Miconazole; Microscopy, Electron, Scanning; Spheroplasts

1982
The role of econazole in the management of oculomycosis.
    International ophthalmology, 1982, Volume: 4, Issue:3

    Topics: Animals; Candidiasis; Clotrimazole; Corneal Diseases; Disease Models, Animal; Econazole; Fungi; Imidazoles; In Vitro Techniques; Male; Miconazole; Mycoses; Rabbits

1982
[In vitro demonstration of the antibacterial and antimycotic efficacy of a preparation containing nystatin and chlorquinaldol compared with similar antimicrobial agents (author's transl)].
    Mykosen, 1980, Volume: 23, Issue:6

    Topics: Bacteria; Chlorquinaldol; Clotrimazole; Drug Combinations; Econazole; Fungi; Miconazole; Nystatin; Species Specificity; Tolnaftate

1980
Antifungal antibiotic sensitivity testing: use of Autobac 1 for standardization purposes.
    Mycopathologia, 1980, Aug-29, Volume: 72, Issue:1

    Topics: Amphotericin B; Antifungal Agents; Candida; Clotrimazole; Econazole; Flucytosine; Miconazole; Microbial Sensitivity Tests; Nystatin

1980
Effect of anti-fungal imidazoles on mRNA levels and enzyme activity of inducible nitric oxide synthase.
    British journal of pharmacology, 1994, Volume: 111, Issue:4

    Topics: Amino Acid Oxidoreductases; Animals; Cells, Cultured; Clotrimazole; Econazole; Enzyme Induction; Macrophages; Mice; Miconazole; Nitric Oxide Synthase; Nitrites; RNA, Messenger

1994
Toxicity of antibiotics and antifungals on cultured human corneal cells: effect of mixing, exposure and concentration.
    Eye (London, England), 1995, Volume: 9 ( Pt 1)

    Topics: Anti-Bacterial Agents; Cell Division; Cell Survival; Cells, Cultured; Chloramphenicol; Clotrimazole; Cornea; Dose-Response Relationship, Drug; Drug Therapy, Combination; Econazole; Gentamicins; Humans; Methicillin; Miconazole

1995
Thapsigargin-induced calcium entry in FRTL-5 cells: possible dependence on phospholipase A2 activation.
    Journal of cellular physiology, 1994, Volume: 160, Issue:1

    Topics: Acetophenones; Animals; Arachidonic Acid; Biological Transport; Calcium; Calcium-Transporting ATPases; Cell Line; Clotrimazole; Dose-Response Relationship, Drug; Econazole; Enzyme Activation; Indomethacin; Leukotrienes; Masoprocol; Phospholipases A; Phospholipases A2; Rats; Terpenes; Thapsigargin; Thyroid Gland

1994
CD3 monoclonal antibodies evoke the same cytochrome P450-regulated capacitative entry of calcium as thapsigargin in Jurkat T cells.
    Cellular immunology, 1993, Volume: 152, Issue:1

    Topics: Calcium; Cell Line; Cell Membrane Permeability; Clotrimazole; Econazole; Humans; Indoles; Indomethacin; Masoprocol; Membrane Potentials; Muromonab-CD3; T-Lymphocytes; Terpenes; Thapsigargin

1993
Direct interaction of antifungal azole-derivatives with calmodulin: a possible mechanism for their therapeutic activity.
    The Journal of investigative dermatology, 1993, Volume: 100, Issue:3

    Topics: Antifungal Agents; Calmodulin; Clotrimazole; Drug Interactions; Econazole; Imidazoles; Ketoconazole; Kinetics; Miconazole; Phosphodiesterase Inhibitors; Polymyxin B

1993
Imidazole antimycotics inhibitors of cytochrome P450 increase phosphatidylserine synthesis similarly to K(+)-channel blockers in Jurkat T cells.
    FEBS letters, 1993, Mar-15, Volume: 319, Issue:1-2

    Topics: Antifungal Agents; Benzoflavones; Calcium; CD3 Complex; Cell Line; Clotrimazole; Cytochrome P-450 Enzyme Inhibitors; Econazole; Humans; Imidazoles; Membrane Potentials; Miconazole; Phosphatidylserines; Potassium Channels; Serine; T-Lymphocytes; Valinomycin

1993
Modulation of human T-lymphocyte plasma membrane Ca2+ permeability by imidazole antimycotics.
    Immunopharmacology and immunotoxicology, 1996, Volume: 18, Issue:2

    Topics: Antifungal Agents; Calcium; Cell Membrane Permeability; Clotrimazole; Cytochrome P-450 Enzyme Inhibitors; Econazole; Enzyme Inhibitors; Humans; Imidazoles; Miconazole; T-Lymphocytes; Thapsigargin

1996
On-line post-column photochemical derivatization in liquid chromatographic--diode-array detection analysis of binary drug mixtures.
    Journal of pharmaceutical and biomedical analysis, 1996, Volume: 14, Issue:8-10

    Topics: Administration, Topical; Anti-Inflammatory Agents; Betamethasone Valerate; Chlorhexidine; Chromatography, Liquid; Clotrimazole; Cresols; Desonide; Dexamethasone; Econazole; Hydrocortisone; Miconazole; Ointments; Photochemistry; Spectrophotometry, Ultraviolet; Triamcinolone Acetonide

1996
Inhibitors of cytochrome P-450 augment fever induced by interleukin-1 beta.
    The American journal of physiology, 1996, Volume: 271, Issue:5 Pt 2

    Topics: Animals; Antifungal Agents; Body Temperature; Clotrimazole; Cytochrome P-450 Enzyme Inhibitors; Econazole; Fever; Hypothalamus, Anterior; Interleukin-1; Male; Preoptic Area; Rats; Rats, Wistar; Sesame Oil

1996
Imidazole antimycotics affect the activity of various ion channels and insulin secretion in mouse pancreatic B-cells.
    Naunyn-Schmiedeberg's archives of pharmacology, 1997, Volume: 356, Issue:5

    Topics: Animals; Antifungal Agents; Clotrimazole; Culture Techniques; Econazole; Electrophysiology; Female; Imidazoles; Insulin; Insulin Secretion; Ion Channels; Islets of Langerhans; Ketoconazole; Mice; Patch-Clamp Techniques

1997
[Effect of imidazole antifungal agents on colony formation by murine bone marrow CFUc (colony forming units in culture].
    Acta pharmaceutica Hungarica, 1996, Volume: 66, Issue:6

    Topics: Animals; Antifungal Agents; Bone Marrow Cells; Cells, Cultured; Clotrimazole; Colony-Forming Units Assay; Econazole; Hematopoietic Stem Cells; Humans; Imidazoles; Ketoconazole; Mice; Miconazole

1996
Inhibition of platelet serotonin uptake by cytochrome P450 inhibitors miconazole and econazole.
    Life sciences, 1998, Volume: 62, Issue:24

    Topics: Benzoflavones; beta-Naphthoflavone; Blood Platelets; Calcium; Clotrimazole; Cytochrome P-450 Enzyme Inhibitors; Drug Combinations; Drugs, Chinese Herbal; Econazole; Enzyme Inhibitors; Glycyrrhiza; Humans; Miconazole; Paeonia; Serotonin

1998
Comparison of the toxicity of fluconazole and other azole antifungal drugs to murine and human granulocyte-macrophage progenitor cells in vitro.
    The Journal of antimicrobial chemotherapy, 1999, Volume: 43, Issue:5

    Topics: Animals; Antifungal Agents; Azoles; Bone Marrow; Cells, Cultured; Clotrimazole; Dose-Response Relationship, Drug; Econazole; Female; Fluconazole; Granulocytes; Hematopoietic Stem Cells; Humans; Imidazoles; Inhibitory Concentration 50; Ketoconazole; Macrophages; Male; Mice; Miconazole; Species Specificity; Stem Cells

1999
In-vitro resistance to azoles associated with mitochondrial DNA deficiency in Candida glabrata.
    Journal of medical microbiology, 1999, Volume: 48, Issue:7

    Topics: Antifungal Agents; Azoles; Candida; Candidiasis; Clotrimazole; DNA, Fungal; DNA, Mitochondrial; Drug Resistance, Microbial; Econazole; Electrophoresis, Agar Gel; Fluconazole; Humans; Imidazoles; Ketoconazole; Miconazole; Microbial Sensitivity Tests; Polyenes

1999
Phospholipase A(2) is involved in thapsigargin-induced sodium influx in human lymphocytes.
    Archives of biochemistry and biophysics, 2000, Feb-15, Volume: 374, Issue:2

    Topics: Acetophenones; Acrylates; Arachidonic Acid; Benzoates; Cell Membrane; Clotrimazole; Econazole; Humans; In Vitro Techniques; Indomethacin; Kinetics; Lymphocytes; Masoprocol; Naphthalenes; Phosphodiesterase Inhibitors; Phospholipases A; Pyrones; Sodium; Thapsigargin

2000
Amino acid 305 determines catalytic center accessibility in CYP3A4.
    Biochemistry, 2000, Apr-18, Volume: 39, Issue:15

    Topics: Alanine; Amino Acid Substitution; Aryl Hydrocarbon Hydroxylases; Binding Sites; Catalysis; Clotrimazole; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Diazepam; Econazole; Erythromycin; Humans; Imidazoles; Ketoconazole; Kinetics; Miconazole; Mixed Function Oxygenases; Multienzyme Complexes; Mutation; Nifedipine; Oxidoreductases, N-Demethylating; Substrate Specificity; Testosterone

2000
Effect of cytochrome P-450 inhibitors econazole, bifonazole and clotrimazole on prostanoid formation.
    British journal of pharmacology, 2000, Volume: 130, Issue:6

    Topics: Animals; Blood Platelets; Cell Line; Clotrimazole; Cyclooxygenase 1; Cytochrome P-450 Enzyme Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Econazole; Enzyme Inhibitors; Humans; Imidazoles; Ionomycin; Isoenzymes; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Thromboxane B2; Tumor Cells, Cultured

2000
Bactericidal and inhibitory effects of azole antifungal compounds on Mycobacterium smegmatis.
    FEMS microbiology letters, 2000, Nov-15, Volume: 192, Issue:2

    Topics: Antifungal Agents; Antitubercular Agents; Azoles; Clotrimazole; Econazole; Growth Inhibitors; Miconazole; Microbial Sensitivity Tests; Mycobacterium smegmatis; Triazoles

2000
Comparison of in vitro activities of amphotericin, clotrimazole, econazole, miconazole, and nystatin against Fusarium oxysporum.
    Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes, 2001, Volume: 36, Issue:3

    Topics: Amphotericin B; Antifungal Agents; Clotrimazole; Cucurbitaceae; Econazole; Fusarium; Kinetics; Miconazole; Microbial Sensitivity Tests; Nystatin; Spores, Fungal

2001
Effect of commercial ethanol propolis extract on the in vitro growth of Candida albicans collected from HIV-seropositive and HIV-seronegative Brazilian patients with oral candidiasis.
    Journal of oral science, 2002, Volume: 44, Issue:1

    Topics: AIDS-Related Opportunistic Infections; Anti-Infective Agents; Antifungal Agents; Brazil; Candida albicans; Candidiasis, Oral; Clotrimazole; Complementary Therapies; Drug Resistance, Fungal; Econazole; Ethanol; Fluconazole; HIV Seronegativity; HIV Seropositivity; Humans; Nystatin; Propolis; Solvents; Statistics, Nonparametric

2002
[The problem of otomycosis treatment].
    Voenno-meditsinskii zhurnal, 2003, Volume: 324, Issue:2

    Topics: Adult; Aged; Antifungal Agents; Capsules; Clotrimazole; Ear Diseases; Econazole; Female; Humans; In Vitro Techniques; Itraconazole; Miconazole; Middle Aged; Ointments; Pulse Therapy, Drug

2003
Strategy for the development of automated methods involving dialysis and trace enrichment as on-line sample preparation for the determination of basic drugs in plasma by liquid chromatography.
    Journal of chromatography. A, 2002, Mar-01, Volume: 948, Issue:1-2

    Topics: Antifungal Agents; Automation; Chromatography, Liquid; Clotrimazole; Dialysis; Econazole; Humans; Hydrogen-Ion Concentration; Indicators and Reagents; Miconazole; Solutions

2002
In vitro antifungal activity of sertaconazole compared with nine other drugs against 250 clinical isolates of dermatophytes and Scopulariopsis brevicaulis.
    Chemotherapy, 2004, Volume: 50, Issue:6

    Topics: Antifungal Agents; Arthrodermataceae; Ascomycota; Clotrimazole; Econazole; Fluconazole; Imidazoles; Itraconazole; Ketoconazole; Miconazole; Microbial Sensitivity Tests; Mitosporic Fungi; Naphthalenes; Terbinafine; Thiophenes

2004
Usage of antifungal drugs for therapy of genital Candida infections, purchased as over-the-counter products or by prescription: I. Analyses of a unique database.
    Infectious diseases in obstetrics and gynecology, 2004, Volume: 12, Issue:2

    Topics: Adolescent; Adult; Antifungal Agents; Candidiasis, Vulvovaginal; Clotrimazole; Databases as Topic; Drug Prescriptions; Econazole; Female; Humans; Miconazole; Middle Aged; Nonprescription Drugs; Pharmacies; Recurrence; Self Medication; Sweden

2004
Altered expression profile of mycobacterial surface glycopeptidolipids following treatment with the antifungal azole inhibitors econazole and clotrimazole.
    Microbiology (Reading, England), 2005, Volume: 151, Issue:Pt 6

    Topics: Antitubercular Agents; Cell Wall; Clotrimazole; Econazole; Ethionamide; Glycolipids; Glycopeptides; Isoniazid; Molecular Structure; Mycobacterium; Mycobacterium avium; Mycobacterium smegmatis

2005
Nano-encapsulation of azole antifungals: potential applications to improve oral drug delivery.
    International journal of pharmaceutics, 2005, Sep-14, Volume: 301, Issue:1-2

    Topics: Administration, Oral; Alginates; Animals; Antifungal Agents; Area Under Curve; Azoles; Biological Availability; Chemistry, Pharmaceutical; Clotrimazole; Drug Compounding; Drug Delivery Systems; Econazole; Female; Injections, Intravenous; Male; Mice; Nanostructures; Particle Size; Reproducibility of Results; Tissue Distribution

2005
In vitro and ex vivo antimycobacterial potential of azole drugs against Mycobacterium tuberculosis H37Rv.
    FEMS microbiology letters, 2005, Oct-01, Volume: 251, Issue:1

    Topics: Anti-Bacterial Agents; Clotrimazole; Colony Count, Microbial; Drug Synergism; Econazole; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Rifampin

2005
The potential of azole antifungals against latent/persistent tuberculosis.
    FEMS microbiology letters, 2006, Volume: 258, Issue:2

    Topics: Animals; Antitubercular Agents; Clotrimazole; Colony Count, Microbial; Econazole; Lung; Mice; Mycobacterium tuberculosis; Spleen; Tuberculosis

2006
Mycobacterium tuberculosis CYP130: crystal structure, biophysical characterization, and interactions with antifungal azole drugs.
    The Journal of biological chemistry, 2008, Feb-22, Volume: 283, Issue:8

    Topics: Antifungal Agents; Bacterial Proteins; Binding Sites; Clotrimazole; Crystallography, X-Ray; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dimerization; Econazole; Entropy; Hydrophobic and Hydrophilic Interactions; Mycobacterium tuberculosis; Protein Binding; Protein Structure, Quaternary; Spectrophotometry, Ultraviolet

2008
Screening of antimycotics in Swedish sewage treatment plants--waters and sludge.
    Water research, 2010, Volume: 44, Issue:2

    Topics: Antifungal Agents; Clotrimazole; Econazole; Environmental Monitoring; Fluconazole; Ketoconazole; Miconazole; Naphthalenes; Sewage; Sweden; Terbinafine; Waste Disposal, Fluid; Water Pollutants, Chemical

2010
Expression and characterization of Mycobacterium tuberculosis CYP144: common themes and lessons learned in the M. tuberculosis P450 enzyme family.
    Biochimica et biophysica acta, 2011, Volume: 1814, Issue:1

    Topics: Anti-Infective Agents, Local; Bacterial Proteins; Binding, Competitive; Cell Division; Clotrimazole; Cytochrome P-450 Enzyme System; Econazole; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Gene Knockout Techniques; Kinetics; Miconazole; Mutation; Mycobacterium tuberculosis; Oxidation-Reduction; Potentiometry; Protein Binding; Recombinant Proteins; Spectrophotometry; Spectrum Analysis, Raman; Time Factors

2011
Binding free energies of inhibitors to iron porphyrin complex as a model for Cytochrome P450.
    Biopolymers, 2012, Volume: 97, Issue:4

    Topics: Biophysics; Clotrimazole; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Econazole; Enzyme Inhibitors; Heme; Humans; Iron; Models, Molecular; Molecular Mimicry; Piroxicam; Porphyrins; Protein Binding; Protein Conformation; Quantum Theory; Thermodynamics; Water; Xenobiotics

2012
Distribution, behavior and fate of azole antifungals during mechanical, biological, and chemical treatments in sewage treatment plants in China.
    The Science of the total environment, 2012, Jun-01, Volume: 426

    Topics: Antifungal Agents; Azoles; Biodegradation, Environmental; China; Clotrimazole; Econazole; Environmental Monitoring; Fluconazole; Ketoconazole; Miconazole; Sewage; Waste Disposal, Fluid; Water Pollutants, Chemical

2012
Activity of imidazole compounds on Leishmania (L.) infantum chagasi: reactive oxygen species induced by econazole.
    Molecular and cellular biochemistry, 2014, Volume: 389, Issue:1-2

    Topics: Antiprotozoal Agents; Cell Membrane; Cell Membrane Permeability; Clotrimazole; Econazole; Imidazoles; Leishmania; Leishmania infantum; Leishmaniasis, Visceral; Membrane Potential, Mitochondrial; Reactive Oxygen Species

2014
Clotrimazole and econazole inhibit Streptococcus mutans biofilm and virulence in vitro.
    Archives of oral biology, 2017, Volume: 73

    Topics: Anti-Bacterial Agents; Antifungal Agents; Biofilms; Clotrimazole; Econazole; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Microbial Sensitivity Tests; Microscopy, Electron, Scanning; Real-Time Polymerase Chain Reaction; Streptococcus mutans; Virulence Factors

2017
In vitro activity of 23 antifungal drugs against 54 clinical and environmental Aspergillus oryzae isolates.
    Mycoses, 2022, Volume: 65, Issue:11

    Topics: Amphotericin B; Anidulafungin; Antifungal Agents; Aspergillus oryzae; Clotrimazole; Econazole; Fluconazole; Griseofulvin; Humans; Itraconazole; Ketoconazole; Miconazole; Microbial Sensitivity Tests; Natamycin; Nystatin; Terbinafine; Tolnaftate; Voriconazole

2022