eckol has been researched along with dieckol in 20 studies
| Studies (eckol) | Trials (eckol) | Recent Studies (post-2010) (eckol) | Studies (dieckol) | Trials (dieckol) | Recent Studies (post-2010) (dieckol) |
|---|---|---|---|---|---|
| 47 | 0 | 32 | 97 | 2 | 82 |
| Protein | Taxonomy | eckol (IC50) | dieckol (IC50) |
|---|---|---|---|
| Replicase polyprotein 1ab | Severe acute respiratory syndrome-related coronavirus | 2.7 | |
| Beta-secretase 1 | Homo sapiens (human) | 2.21 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (25.00) | 29.6817 |
| 2010's | 14 (70.00) | 24.3611 |
| 2020's | 1 (5.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ishimaru, A; Okada, Y; Okuyama, T; Suzuki, R | 1 |
| Kim, MM; Kim, SK; Lee, SH; Li, Y; Qian, ZJ; Ryu, B | 1 |
| Choi, JS; Jung, HA; Oh, SH | 1 |
| Bae, JS; Kim, TH; Ku, SK; Lee, T | 2 |
| Jeong, HJ; Kim, D; Kim, JH; Kim, YM; Kwon, HJ; Kwon, JM; Lee, WS; Park, JY; Ryu, YB | 1 |
| Cao, W; Jian, Y; Ju, X; Li, H; Liang, C; Liu, H; Liu, Y; Ren, X; Tian, L; Wang, Y; Xie, X; Xin, L; Zhang, D; Zhao, Q | 1 |
| Choi, HY; Joe, MJ; Kang, DW; Kim, SN; Kim, YK; Park, GM; Shin, WS | 1 |
| Chen, T; Hwang, H; Nines, RG; Shin, HC; Stoner, GD | 1 |
| Choi, JS; Chung, HY; Kim, HR; Yoon, NY | 1 |
| Choi, JS; Goo, HR; Na, DH | 1 |
| Ahn, BR; Choi, JS; Chowdhury, SS; Islam, N; Jung, HA; Moon, HE; Sohn, HS | 1 |
| Eom, SH; Kim, TH; Kim, YM; Lee, EW; Lee, MS | 1 |
| Bae, JS; Kim, TH; Ku, SK | 1 |
| Cha, SH; Jeon, YJ; Kang, MC; Kang, SM; Kim, EA; Lee, SH; Song, CB; Wijesinghe, WA | 1 |
| Choi, JS; Choung, SY; Jung, HA; Kim, JI | 1 |
| Choi, JS; Jung, HA; Jung, JH; Roy, A | 1 |
| Ahn, MR; Jun, M; Kim, DH; Kim, OY; Lee, S; Yoon, E; Youn, K | 1 |
| Jun, M; Lee, J | 1 |
| Choi, JS; Jung, HA; Paudel, P; Seong, SH | 1 |
1 review(s) available for eckol and dieckol
| Article | Year |
|---|---|
The development of Coronavirus 3C-Like protease (3CL
Topics: Antiviral Agents; Coronavirus 3C Proteases; Cysteine Endopeptidases; Humans; Peptidomimetics; Protease Inhibitors; Viral Nonstructural Proteins | 2020 |
19 other study(ies) available for eckol and dieckol
| Article | Year |
|---|---|
A new phloroglucinol derivative from the brown alga Eisenia bicyclis: potential for the effective treatment of diabetic complications.
Topics: alpha-Amylases; Diabetes Mellitus; Enzyme Inhibitors; Glycation End Products, Advanced; Japan; Molecular Structure; Phaeophyceae; Phloroglucinol | 2004 |
Chemical components and its antioxidant properties in vitro: an edible marine brown alga, Ecklonia cava.
Topics: Animals; Antioxidants; Cell Line; Dioxins; Free Radical Scavengers; HL-60 Cells; Humans; Mice; Phaeophyceae; Reactive Oxygen Species; Sterols; Structure-Activity Relationship; Tannins | 2009 |
Molecular docking studies of phlorotannins from Eisenia bicyclis with BACE1 inhibitory activity.
Topics: Amyloid Precursor Protein Secretases; Aspartic Acid Endopeptidases; Enzyme Inhibitors; Kinetics; Models, Molecular; Tannins | 2010 |
Vascular barrier protective effects of eckol and its derivatives.
Topics: Acetic Acid; Animals; Carboxymethylcellulose Sodium; Cell Membrane Permeability; Cell Movement; Dioxins; Human Umbilical Vein Endothelial Cells; Humans; Leukocytes; Lipopolysaccharides; Mice; Protective Agents | 2012 |
Dieckol, a SARS-CoV 3CL(pro) inhibitor, isolated from the edible brown algae Ecklonia cava.
Topics: Antiviral Agents; Benzofurans; Cysteine Proteases; Cysteine Proteinase Inhibitors; Humans; Molecular Docking Simulation; Phaeophyceae; Quantitative Structure-Activity Relationship; Severe Acute Respiratory Syndrome; Severe acute respiratory syndrome-related coronavirus | 2013 |
The inhibitory effects of eckol and dieckol from Ecklonia stolonifera on the expression of matrix metalloproteinase-1 in human dermal fibroblasts.
Topics: Base Sequence; Benzofurans; Blotting, Western; Cells, Cultured; Dioxins; DNA Primers; Fibroblasts; Humans; Matrix Metalloproteinase 1; Phaeophyceae; Reverse Transcriptase Polymerase Chain Reaction; Skin | 2006 |
Photochemoprevention of UVB-induced skin carcinogenesis in SKH-1 mice by brown algae polyphenols.
Topics: Administration, Cutaneous; Administration, Oral; Animals; Benzofurans; Blotting, Western; Cell Proliferation; Cyclooxygenase 2; Dinoprostone; Dioxins; Epidermis; Female; Flavonoids; Gene Expression; Immunohistochemistry; Mice; Molecular Structure; Neoplasms, Radiation-Induced; Phaeophyceae; Phenols; Polyphenols; Proliferating Cell Nuclear Antigen; Random Allocation; Reverse Transcriptase Polymerase Chain Reaction; Skin; Skin Neoplasms; Ultraviolet Rays | 2006 |
Anti-hyperlipidemic effect of an edible brown algae, Ecklonia stolonifera, and its constituents on poloxamer 407-induced hyperlipidemic and cholesterol-fed rats.
Topics: Animals; Benzofurans; Cholesterol, Dietary; Diet; Dioxins; Ethanol; Freeze Drying; Hyperlipidemias; Hypolipidemic Agents; Male; Phaeophyceae; Poloxamer; Rats; Rats, Sprague-Dawley; Solvents; Tannins; Triglycerides | 2008 |
Quantitative determination of major phlorotannins in Ecklonia stolonifera.
Topics: Benzofurans; Chromatography, High Pressure Liquid; Dioxins; Phaeophyceae; Plants, Medicinal; Spectrometry, Mass, Electrospray Ionization; Tannins | 2010 |
Protein tyrosine phosphatase 1B and α-glucosidase inhibitory Phlorotannins from edible brown algae, Ecklonia stolonifera and Eisenia bicyclis.
Topics: alpha-Glucosidases; Benzofurans; Blood Glucose; Complex Mixtures; Diabetes Mellitus; Dioxins; Enzyme Inhibitors; Glycoside Hydrolase Inhibitors; Humans; Hyperglycemia; Hypoglycemic Agents; Kinetics; Magnetic Resonance Spectroscopy; Phaeophyceae; Phloroglucinol; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Solutions; Spectrophotometry; Tannins; Yeasts | 2011 |
Pancreatic lipase inhibitory activity of phlorotannins isolated from Eisenia bicyclis.
Topics: Animals; Benzofurans; Dioxins; Inhibitory Concentration 50; Lipase; Oxindoles; Phaeophyceae; Swine; Tannins | 2013 |
Vascular barrier protective effects of phlorotannins on HMGB1-mediated proinflammatory responses in vitro and in vivo.
Topics: Animals; Benzofurans; Blood Vessels; Blotting, Western; Cell Adhesion Molecules; Cell Membrane Permeability; Cell Movement; Cell Survival; Dioxins; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Female; HMGB1 Protein; Humans; Inflammation; Kelp; Lipopolysaccharides; Mice; Mice, Inbred ICR; Phloroglucinol; Spectrometry, Mass, Electrospray Ionization; Tannins; Toll-Like Receptor 4 | 2012 |
Antithrombotic and profibrinolytic activities of eckol and dieckol.
Topics: Animals; Benzofurans; Dioxins; Enzyme-Linked Immunosorbent Assay; Factor Xa; Fibrinolysis; Fibrinolytic Agents; Human Umbilical Vein Endothelial Cells; Humans; Male; Mice; Mice, Inbred ICR; Prothrombin; Thrombin; Tissue Plasminogen Activator; Tumor Necrosis Factor-alpha | 2012 |
Protective effect of marine algae phlorotannins against AAPH-induced oxidative stress in zebrafish embryo.
Topics: Amidines; Animals; Antioxidants; Benzofurans; Dioxins; Oxidative Stress; Phaeophyceae; Phloroglucinol; Protective Agents; Zebrafish | 2013 |
Protective effect of the edible brown alga Ecklonia stolonifera on doxorubicin-induced hepatotoxicity in primary rat hepatocytes.
Topics: Animals; Benzofurans; Dioxins; Doxorubicin; Hepatocytes; Male; Phaeophyceae; Phloroglucinol; Protective Agents; Rats; Rats, Sprague-Dawley; Seaweed | 2014 |
Evaluation of the inhibitory effects of eckol and dieckol isolated from edible brown alga Eisenia bicyclis on human monoamine oxidases A and B.
Topics: Benzofurans; Dioxins; Dose-Response Relationship, Drug; Humans; Molecular Docking Simulation; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Phaeophyceae; Structure-Activity Relationship | 2017 |
Anti-Neuroinflammatory Property of Phlorotannins from
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Apoptosis; Benzofurans; Cyclooxygenase 2; Dioxins; Down-Regulation; Drug Evaluation, Preclinical; MAP Kinase Signaling System; Neuroprotective Agents; NF-kappa B; Nitric Oxide Synthase Type II; PC12 Cells; Peptide Fragments; Phaeophyceae; Rats; Seaweed | 2018 |
Dual BACE1 and Cholinesterase Inhibitory Effects of Phlorotannins from
Topics: ADAM17 Protein; Alzheimer Disease; Amyloid Precursor Protein Secretases; Aspartic Acid Endopeptidases; Benzofurans; Cholinesterase Inhibitors; Cholinesterases; Dioxins; Molecular Docking Simulation; Seaweed; Tannins | 2019 |
Identifying Phlorofucofuroeckol-A as a Dual Inhibitor of Amyloid-β
Topics: Amyloid beta-Peptides; Benzofurans; Dioxins; Glycation End Products, Advanced; Lipid Peroxidation; Molecular Docking Simulation; Molecular Structure; Phaeophyceae; Phloroglucinol; Protein Aggregation, Pathological | 2019 |