Page last updated: 2024-09-04

echinoside a and holothurin

echinoside a has been researched along with holothurin in 15 studies

Compound Research Comparison

Studies
(echinoside a)
Trials
(echinoside a)
Recent Studies (post-2010)
(echinoside a)
Studies
(holothurin)
Trials
(holothurin)
Recent Studies (post-2010) (holothurin)
1501260020

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19902 (13.33)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's11 (73.33)24.3611
2020's2 (13.33)2.80

Authors

AuthorsStudies
Fuchida, M; Inamoto, T; Kitagawa, I; Kobayashi, M; Kyogoku, Y1
Jo, IH; Yu, BS1
Chen, Q; Chen, Z; Ding, J; Gui, M; Li, M; Lin, LP; Miao, ZH; Sun, P; Yi, YH1
Dong, P; Li, H; Liu, ZD; Tang, QJ; Wang, JF; Wang, YM; Xue, CH; Xue, Y; Zhao, Q1
Dong, P; Li, H; Li, Z; Long, TT; Wang, JF; Wang, YM; Xue, CH; Xue, Y; Zhao, Q1
Hassan, MH; Melek, FR; Selim, MA; Tadros, MM; Yousif, F1
Dong, P; Hu, X; Liu, C; Wang, J; Wang, Y; Xue, C; Xue, Y; Yanagita, RC1
Chen, Y; Gao, Z; Guo, F; Guo, L; Huang, C; Li, Y; Zhang, L1
Jiang, T; Li, S; Lv, Z; Wang, H; Wang, Y; Yang, S1
Dong, P; Fu, X; Han, X; Hu, X; Wang, J; Wang, Y; Wen, M; Xu, J; Xue, C; Xue, Y1
Chen, X; Li, W; Shao, X; Yu, B; Zhang, X1
Cao, J; Cong, P; Dong, P; Li, Z; Song, S; Wang, Y; Xiang, G; Xue, C; Xue, Y; Zhang, L1
Shao, X; Xiao, G; Yu, B; Zhu, D1
Chi, N; Chu, Y; Dong, P; Han, X; Li, R; Li, Z; Wang, C; Wang, Y; Xue, C; Zhang, T1
Bai, X; Li, Y; Li, Z; Tian, Y; Wang, J; Wang, X; Wang, Y; Xue, C; Yue, H1

Reviews

1 review(s) available for echinoside a and holothurin

ArticleYear
Chemical synthesis of marine saponins.
    Natural product reports, 2019, 05-22, Volume: 36, Issue:5

    Topics: Aminoglycosides; Animals; Aquatic Organisms; Cholestenones; Cholesterol; Holothurin; Saponins; Sea Cucumbers; Starfish; Steroids

2019

Other Studies

14 other study(ies) available for echinoside a and holothurin

ArticleYear
Marine natural products. XIV. Structures of echinosides A and B, antifungal lanostane-oligosides from the sea cucumber Actinopyga echinites (Jaeger).
    Chemical & pharmaceutical bulletin, 1985, Volume: 33, Issue:12

    Topics: Antifungal Agents; Chemical Phenomena; Chemistry; Echinodermata; Holothurin; Magnetic Resonance Spectroscopy; Saponins; Sea Cucumbers

1985
Interaction of sea cucumber saponins with multilamellar liposomes.
    Chemico-biological interactions, 1984, Volume: 52, Issue:2

    Topics: Animals; Cholesterol; Holothurin; Kinetics; Liposomes; Microscopy, Electron; Molecular Conformation; Phosphatidic Acids; Phosphatidylcholines; Saponins; Sea Cucumbers; Structure-Activity Relationship

1984
Echinoside A, a new marine-derived anticancer saponin, targets topoisomerase2alpha by unique interference with its DNA binding and catalytic cycle.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2010, Volume: 21, Issue:3

    Topics: Animals; Antigens, Neoplasm; Apoptosis; Blotting, Western; Catalysis; Cell Proliferation; DNA; DNA Breaks, Double-Stranded; DNA Topoisomerases, Type II; DNA-Binding Proteins; Female; Holothurin; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Models, Molecular; Neoplasms, Experimental; Poly-ADP-Ribose Binding Proteins; Protein Conformation; Sea Cucumbers; Topoisomerase II Inhibitors; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2010
Ds-echinoside A, a new triterpene glycoside derived from sea cucumber, exhibits antimetastatic activity via the inhibition of NF-κB-dependent MMP-9 and VEGF expressions.
    Journal of Zhejiang University. Science. B, 2011, Volume: 12, Issue:7

    Topics: Animals; Antineoplastic Agents; Cell Adhesion; Cell Movement; Cell Proliferation; Chick Embryo; Endothelial Cells; Hep G2 Cells; Holothurin; Humans; Matrix Metalloproteinase Inhibitors; Neoplasm Invasiveness; Neoplasm Metastasis; NF-kappa B; Sea Cucumbers; Vascular Endothelial Growth Factor A

2011
In vitro and in vivo anti-tumour activities of echinoside A and ds-echinoside A from Pearsonothuria graeffei.
    Journal of the science of food and agriculture, 2012, Mar-15, Volume: 92, Issue:4

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle Proteins; Cell Proliferation; Cell Survival; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Holothurin; Humans; Liver Neoplasms; Male; Mice; Mice, Inbred BALB C; Neoplasm Proteins; NF-kappa B; Random Allocation; Resting Phase, Cell Cycle; RNA, Messenger; Sea Cucumbers; Structure-Activity Relationship

2012
Screening of marine extracts for schistosomicidal activity in vitro. Isolation of the triterpene glycosides echinosides A and B with potential activity from the Sea Cucumbers Actinopyga echinites and Holothuria polii.
    Pharmaceutical biology, 2012, Volume: 50, Issue:4

    Topics: Animals; Biological Assay; Chromatography; Holothuria; Holothurin; Magnetic Resonance Spectroscopy; Methanol; Molecular Structure; Schistosoma mansoni; Schistosomicides; Sea Cucumbers; Solvents

2012
Effects of two sulfated triterpene saponins echinoside A and holothurin A on the inhibition of dietary fat absorption and obesity reduction.
    Bioscience, biotechnology, and biochemistry, 2014, Volume: 78, Issue:1

    Topics: Absorption, Physicochemical; Animals; Body Weight; Dietary Fats; Eating; Holothurin; Lipase; Liver; Male; Mice; Molecular Docking Simulation; Obesity; Organ Size; Pancreas; Protein Conformation; Rats

2014
Saponin-enriched sea cucumber extracts exhibit an antiobesity effect through inhibition of pancreatic lipase activity and upregulation of LXR-β signaling.
    Pharmaceutical biology, 2016, Volume: 54, Issue:8

    Topics: Adipocytes, White; Animals; Anti-Obesity Agents; Diet, High-Fat; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Hep G2 Cells; Holothurin; Humans; Intestinal Absorption; Lipase; Lipids; Liver; Liver X Receptors; Mice, Inbred C57BL; Obesity; Pancreas; Saponins; Sea Cucumbers; Signal Transduction; Time Factors; Up-Regulation; Weight Gain

2016
Absorption and Transport of Sea Cucumber Saponins from Apostichopus japonicus.
    Marine drugs, 2016, Jun-17, Volume: 14, Issue:6

    Topics: Animals; Biological Availability; Biological Transport; Caco-2 Cells; Cell Line, Tumor; Glycosides; Holothurin; Humans; Intestinal Absorption; Intestinal Mucosa; Male; Rats; Rats, Wistar; Saponins; Sea Cucumbers; Stichopus; Triterpenes

2016
Sea Cucumber Saponin Echinoside A (EA) Stimulates Hepatic Fatty Acid β-Oxidation and Suppresses Fatty Acid Biosynthesis Coupling in a Diurnal Pattern.
    Journal of nutritional science and vitaminology, 2016, Volume: 62, Issue:3

    Topics: Animals; Circadian Rhythm; Fatty Acids; Gene Expression; Holothurin; Lipid Metabolism; Lipogenesis; Lipolysis; Liver; Male; Mice; Mice, Inbred ICR; Oxidation-Reduction; Sea Cucumbers

2016
Total Synthesis of Echinoside A, a Representative Triterpene Glycoside of Sea Cucumbers.
    Angewandte Chemie (International ed. in English), 2017, 06-19, Volume: 56, Issue:26

    Topics: Animals; Antifungal Agents; Antineoplastic Agents; Carbohydrate Conformation; Carbohydrate Sequence; Feasibility Studies; Holothurin; Sea Cucumbers; Triterpenes

2017
Characterization of Metabolic Pathways and Absorption of Sea Cucumber Saponins, Holothurin A and Echinoside A, in Vitro and in Vivo.
    Journal of food science, 2017, Volume: 82, Issue:8

    Topics: Animals; Chromatography, High Pressure Liquid; Feces; Gastrointestinal Microbiome; Holothurin; Intestinal Mucosa; Intestines; Male; Mass Spectrometry; Metabolic Networks and Pathways; Rats; Saponins; Sea Cucumbers

2017
Relationship between structure and efficacy of sea cucumber saponins echinoside A and its derivatives on hemolytic activity and prevention of nonalcoholic fatty liver disease.
    Journal of food science, 2020, Volume: 85, Issue:7

    Topics: Animals; Holothurin; Humans; Lipid Metabolism; Lipogenesis; Lipolysis; Liver; Male; Non-alcoholic Fatty Liver Disease; Rats; Rats, Wistar; Saponins; Sea Cucumbers

2020
Comparative study of holothurin A and echinoside A on inhibiting the high bone turnover
    Food & function, 2022, Apr-20, Volume: 13, Issue:8

    Topics: Animals; beta Catenin; Bone Resorption; Catenins; Female; Holothurin; Humans; Mice; NF-kappa B; Osteoclasts; Osteogenesis; Osteoporosis; Ovariectomy; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; RANK Ligand; Signal Transduction

2022