echinocandin-b and glyoxylic-acid

echinocandin-b has been researched along with glyoxylic-acid* in 1 studies

Other Studies

1 other study(ies) available for echinocandin-b and glyoxylic-acid

Article	Year
Synthesis of β,γ-dihydroxyhomotyrosines by a tandem Petasis-asymmetric dihydroxylation approach. Organic letters, 2011, Jun-03, Volume: 13, Issue:11 Petasis reactions of substituted styrenylboronic acids and glyoxylic acid, employing tert-butylsulfinamide as the 'amine' component, proceed with high stereoselectivity to produce β,γ-dehydrohomoarylalanine derivatives. Subsequent asymmetric dihydroxylation under neutral conditions gives the corresponding protected β,γ-dihydroxyhomoarylalanines with up to 15:1 dr. The method has been exploited in the efficient, stereoselective synthesis of protected β,γ-dihydroxyhomotyrosine, a component of the antifungal cyclic peptide echinocandin B. Topics: Antifungal Agents; Echinocandins; Fungal Proteins; Glyoxylates; Molecular Structure; Stereoisomerism; Tyrosine	2011

Article

Year

Synthesis of β,γ-dihydroxyhomotyrosines by a tandem Petasis-asymmetric dihydroxylation approach.

Organic letters, 2011, Jun-03, Volume: 13, Issue:11

Petasis reactions of substituted styrenylboronic acids and glyoxylic acid, employing tert-butylsulfinamide as the 'amine' component, proceed with high stereoselectivity to produce β,γ-dehydrohomoarylalanine derivatives. Subsequent asymmetric dihydroxylation under neutral conditions gives the corresponding protected β,γ-dihydroxyhomoarylalanines with up to 15:1 dr. The method has been exploited in the efficient, stereoselective synthesis of protected β,γ-dihydroxyhomotyrosine, a component of the antifungal cyclic peptide echinocandin B.

Topics: Antifungal Agents; Echinocandins; Fungal Proteins; Glyoxylates; Molecular Structure; Stereoisomerism; Tyrosine

2011