ebselen and valproic acid

ebselen has been researched along with valproic acid in 3 studies

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	1 (33.33)	24.3611
2020's	2 (66.67)	2.80

Authors

Authors	Studies
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M	1
Cowen, PJ; Godlewska, BR; Holder, AA; MacDonald, O; Shanyinde, M; Sharpley, AL; Singh, N; Williams, C	1

Trials

1 trial(s) available for ebselen and valproic acid

Article	Year
A phase 2a randomised, double-blind, placebo-controlled, parallel-group, add-on clinical trial of ebselen (SPI-1005) as a novel treatment for mania or hypomania. Psychopharmacology, 2020, Volume: 237, Issue:12 Topics: Adult; Aged; Antimanic Agents; Azoles; Bipolar Disorder; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Isoindoles; Male; Mania; Middle Aged; Neuroprotective Agents; Organoselenium Compounds; Treatment Outcome; Valproic Acid; Young Adult	2020

Article

Year

A phase 2a randomised, double-blind, placebo-controlled, parallel-group, add-on clinical trial of ebselen (SPI-1005) as a novel treatment for mania or hypomania.

Psychopharmacology, 2020, Volume: 237, Issue:12

Topics: Adult; Aged; Antimanic Agents; Azoles; Bipolar Disorder; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Isoindoles; Male; Mania; Middle Aged; Neuroprotective Agents; Organoselenium Compounds; Treatment Outcome; Valproic Acid; Young Adult

2020

Other Studies

2 other study(ies) available for ebselen and valproic acid

Article	Year
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology. Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3 Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries	2023

Article

Year

Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.

Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012

In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.

Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023