ebselen and tyrosine

ebselen has been researched along with tyrosine in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's11 (68.75)29.6817
2010's4 (25.00)24.3611
2020's1 (6.25)2.80

Authors

AuthorsStudies
Alexander, RW; Becker, PL; Griendling, KK; Halleran, S; Hilenski, L; Ushio-Fukai, M1
Akaike, T; Hayashida, K; Maeda, H; Okamoto, T; Okuyama, A; Wu, J1
Brodsky, S; Fujita, T; Goligorsky, MS; Nakao, A; Noiri, E; Ohno, M; Tsukahara, H; Uchida, K1
Hirano, K; Iijima, H; Iishii, Y; Masuyama, K; Mochizuki, M; Morishima, Y; Nomura, A; Sakamoto, T; Sekizawa, K; Uchida, Y; Zhang, M1
Bauer, G; Bechtel, W; Heigold, S; Ivanovas, B; Schäfer, R; Sers, C1
Brodsky, SV; Chen, J; Crabtree, M; Gealekman, O; Goligorsky, MS; Gross, SS; Nasjletti, A; Togashi, N; Zhang, F1
Cho, EJ; Rhyu, DY; Yokozawa, T1
Dekhuijzen, PN; Ennen, L; Heunks, LM; van der Heijden, HF; van Kuppevelt, TH; Versteeg, EM; Vina, J; Zhu, X1
Bubolz, AH; Gutterman, DD; Liu, Y; Newman, DK; Newman, PJ; Shi, Y1
Bubolz, AH; Gutterman, DD; Larsen, BT; Liu, Y; Wu, Q1
Chew, P; Cooper, ME; de Haan, JB; Febbraio, MA; Koh, P; Kola, I; Stefanovic, N; Yuen, DY1
Chew, P; Cooper, ME; Coughlan, MT; de Haan, JB; Jandeleit-Dahm, KA; Pete, J; Rosenfeldt, F; Stefanovic, N; Thomas, MC; Yuen, DY1
Fukushima, K; Kagota, S; Maruyama, K; Shinozuka, K; Tada, Y; Umetani, K; Wakuda, H1
Arias, P; Del Rio, R; Iturriaga, R; Moya, EA; Oyarce, MP; Varela, C1
Beckman, JA; Creager, MA; Goldfine, AB; Leopold, JA1
Chen, M; Li, Q; Li, S; Lu, T; Min, S; Zhang, C1

Trials

1 trial(s) available for ebselen and tyrosine

ArticleYear
Ebselen does not improve oxidative stress and vascular function in patients with diabetes: a randomized, crossover trial.
    American journal of physiology. Heart and circulatory physiology, 2016, 12-01, Volume: 311, Issue:6

    Topics: Adult; Antioxidants; Azoles; Brachial Artery; Case-Control Studies; Cross-Over Studies; Diabetes Mellitus; Dinoprost; Double-Blind Method; Endothelium, Vascular; Female; Forearm; Glutathione; Humans; Isoindoles; Male; Methacholine Chloride; Middle Aged; Organoselenium Compounds; Oxidative Stress; Parasympathomimetics; Plethysmography; Tyrosine; Ultrasonography; Vasodilation

2016

Other Studies

15 other study(ies) available for ebselen and tyrosine

ArticleYear
Epidermal growth factor receptor transactivation by angiotensin II requires reactive oxygen species in vascular smooth muscle cells.
    Arteriosclerosis, thrombosis, and vascular biology, 2001, Volume: 21, Issue:4

    Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Angiotensin II; Animals; Antioxidants; Azoles; ErbB Receptors; Isoindoles; Male; Muscle, Smooth, Vascular; Onium Compounds; Organoselenium Compounds; Phosphorylation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptor, ErbB-2; Transcriptional Activation; Tyrosine

2001
Enhanced vascular permeability in solid tumor involving peroxynitrite and matrix metalloproteinases.
    Japanese journal of cancer research : Gann, 2001, Volume: 92, Issue:4

    Topics: Adenocarcinoma; Animals; Azoles; Bradykinin; Capillary Permeability; Collagenases; Colonic Neoplasms; Dose-Response Relationship, Drug; Enzyme Precursors; Free Radical Scavengers; Gelatinases; Guinea Pigs; Isoindoles; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Metalloendopeptidases; Mice; Mice, Inbred C57BL; Nitrates; Oligopeptides; Organoselenium Compounds; Protease Inhibitors; Sarcoma 180; Skin; Tyrosine; Uric Acid

2001
Oxidative and nitrosative stress in acute renal ischemia.
    American journal of physiology. Renal physiology, 2001, Volume: 281, Issue:5

    Topics: Animals; Azoles; Blotting, Western; Cell Line; Cyclic N-Oxides; DNA Damage; Enzyme Inhibitors; Free Radical Scavengers; Immunohistochemistry; Ischemia; Isoindoles; Kidney; Lipid Peroxidation; Lysine; Macrophages; Male; Mice; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Organoselenium Compounds; Oxidative Stress; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Spin Labels; Superoxide Dismutase; Tyrosine

2001
Ebselen suppresses late airway responses and airway inflammation in guinea pigs.
    Free radical biology & medicine, 2002, Mar-01, Volume: 32, Issue:5

    Topics: Airway Resistance; Animals; Antineoplastic Agents, Alkylating; Antioxidants; Area Under Curve; Asthma; Azoles; Bronchitis; Bronchoalveolar Lavage Fluid; Cyclophosphamide; Disease Models, Animal; Endothelium, Vascular; Enzyme Activation; Female; Guinea Pigs; Hydrogen Peroxide; Immunoenzyme Techniques; Isoindoles; Lung; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Organoselenium Compounds; Ovalbumin; Peptide Fragments; Rabbits; Reactive Nitrogen Species; Reactive Oxygen Species; Respiratory Function Tests; Respiratory Hypersensitivity; Superoxides; Tyrosine

2002
Nitric oxide mediates apoptosis induction selectively in transformed fibroblasts compared to nontransformed fibroblasts.
    Carcinogenesis, 2002, Volume: 23, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Azoles; Biomarkers; Cell Line; Cell Line, Transformed; Cell Transformation, Neoplastic; Fibroblasts; Genes, src; Glutathione; Isoindoles; Kinetics; Mitochondria; Nitric Oxide; Nitric Oxide Donors; Nitrogen Oxides; Nitroprusside; Organoselenium Compounds; Rats; S-Nitrosoglutathione; Spermine; Tyrosine

2002
Prevention and reversal of premature endothelial cell senescence and vasculopathy in obesity-induced diabetes by ebselen.
    Circulation research, 2004, Feb-20, Volume: 94, Issue:3

    Topics: Acetylcholine; Animals; Antioxidants; Aorta, Thoracic; Azoles; Cell Cycle Proteins; Cellular Senescence; Diabetes Mellitus; Endothelial Cells; Endothelium, Vascular; In Vitro Techniques; Isoindoles; Microcirculation; Muscle, Skeletal; Neovascularization, Physiologic; Nitric Oxide; Obesity; Organoselenium Compounds; Rats; Rats, Zucker; Tyrosine; Vasodilation; Vasodilator Agents

2004
(-)-Epicatechin 3-O-gallate ameliorates the damages related to peroxynitrite production by mechanisms distinct from those of other free radical inhibitors.
    The Journal of pharmacy and pharmacology, 2004, Volume: 56, Issue:2

    Topics: Animals; Azoles; Blood Urea Nitrogen; Catechin; Copper; Creatinine; Disease Models, Animal; Dose-Response Relationship, Drug; Free Radical Scavengers; Isoindoles; Japan; Kidney; Lipopolysaccharides; Lysine; Male; Nitric Oxide; Organoselenium Compounds; Peroxidase; Phytotherapy; Plant Extracts; Plant Roots; Proteinuria; Rats; Rats, Wistar; Reperfusion Injury; Rheum; Superoxide Dismutase; Tyrosine; Uric Acid; Zinc

2004
Hypoxia-induced dysfunction of rat diaphragm: role of peroxynitrite.
    American journal of physiology. Lung cellular and molecular physiology, 2005, Volume: 288, Issue:1

    Topics: Animals; Azoles; Diaphragm; Enzyme Inhibitors; Hypoxia; In Vitro Techniques; Isoindoles; Lipid Peroxidation; Male; Muscle Contraction; Muscle Fatigue; omega-N-Methylarginine; Organoselenium Compounds; Peroxynitrous Acid; Rats; Rats, Wistar; Tyrosine

2005
Peroxynitrite reduces the endothelium-derived hyperpolarizing factor component of coronary flow-mediated dilation in PECAM-1-knockout mice.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2006, Volume: 290, Issue:1

    Topics: Animals; Azoles; Biological Factors; Coronary Vessels; Gene Deletion; Hydrogen Peroxide; Indomethacin; Isoindoles; Male; Mice; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide; Organoselenium Compounds; Peroxynitrous Acid; Platelet Endothelial Cell Adhesion Molecule-1; Prostaglandins; Tyrosine; Vasodilation

2006
Ebselen reduces nitration and restores voltage-gated potassium channel function in small coronary arteries of diabetic rats.
    American journal of physiology. Heart and circulatory physiology, 2007, Volume: 293, Issue:4

    Topics: Adenylyl Cyclases; Animals; Antioxidants; Azoles; Colforsin; Coronary Vessels; Cyclic AMP; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Enzyme Activators; Isoindoles; Kv1.2 Potassium Channel; Kv1.5 Potassium Channel; Male; Membrane Potentials; Muscle, Smooth, Vascular; Organoselenium Compounds; Oxidative Stress; Peroxynitrous Acid; Potassium Channel Blockers; Protein Subunits; Rats; Rats, Sprague-Dawley; Research Design; Triterpenes; Tyrosine; Vasodilation

2007
Site-specific antiatherogenic effect of the antioxidant ebselen in the diabetic apolipoprotein E-deficient mouse.
    Arteriosclerosis, thrombosis, and vascular biology, 2009, Volume: 29, Issue:6

    Topics: Administration, Oral; Animals; Antioxidants; Aorta, Abdominal; Aorta, Thoracic; Aortic Diseases; Apolipoproteins E; Atherosclerosis; Azoles; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Endothelial Cells; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Humans; I-kappa B Kinase; Isoindoles; JNK Mitogen-Activated Protein Kinases; Macrophages; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; NADPH Oxidase 2; NADPH Oxidases; Organoselenium Compounds; Phenotype; Phosphorylation; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Time Factors; Tumor Necrosis Factor-alpha; Tyrosine; Vascular Endothelial Growth Factor A

2009
Antiatherosclerotic and renoprotective effects of ebselen in the diabetic apolipoprotein E/GPx1-double knockout mouse.
    Diabetes, 2010, Volume: 59, Issue:12

    Topics: Aldehydes; Animals; Antioxidants; Apolipoproteins E; Atherosclerosis; Azoles; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Diabetic Nephropathies; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Isoindoles; Kidney; Male; Mice; Mice, Knockout; Organoselenium Compounds; Reactive Oxygen Species; Tyrosine; Vascular Cell Adhesion Molecule-1

2010
Chronic oxidative-nitrosative stress impairs coronary vasodilation in metabolic syndrome model rats.
    Microvascular research, 2013, Volume: 88

    Topics: Animals; Azoles; Coronary Vessels; Cyclic N-Oxides; Disease Models, Animal; Down-Regulation; Free Radical Scavengers; Guanylate Cyclase; Heart; Isoindoles; Male; Metabolic Syndrome; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrogen; Organoselenium Compounds; Oxidative Stress; Phosphorylation; Rats; Receptor, Angiotensin, Type 1; RNA, Messenger; Spin Labels; Superoxides; Tyrosine; Vasodilation

2013
Intermittent Hypoxia-Induced Carotid Body Chemosensory Potentiation and Hypertension Are Critically Dependent on Peroxynitrite Formation.
    Oxidative medicine and cellular longevity, 2016, Volume: 2016

    Topics: Animals; Azoles; Blood Pressure; Carotid Body; Diastole; Hypertension; Hypoxia; Isoindoles; Male; Neuronal Plasticity; Organoselenium Compounds; Peroxynitrous Acid; Rats, Sprague-Dawley; Systole; Tyrosine

2016
The role of oxidative stress in the susceptibility of noise-impaired cochleae to synaptic loss induced by intracochlear electrical stimulation.
    Neuropharmacology, 2021, 09-15, Volume: 196

    Topics: Action Potentials; Aldehydes; Animals; Antioxidants; Cochlea; Cochlear Implants; Electric Stimulation; Evoked Potentials, Auditory, Brain Stem; Fatty Acids, Unsaturated; Guinea Pigs; Hair Cells, Auditory, Inner; Hearing Loss, Noise-Induced; Hydroxy Acids; Isoindoles; Organoselenium Compounds; Oxidative Stress; Severity of Illness Index; Synapses; Tyrosine

2021