ebselen and tacrine

ebselen has been researched along with tacrine in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's5 (83.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Huang, L; Li, X; Liu, A; Lu, C; Luo, HB; Luo, Z; Sheng, J; Sun, Y; Yan, J1
Chen, J; Huang, L; Li, X; Luo, Z; Mao, F; Zhou, Q1
Huang, L; Li, J; Li, X; Liang, L; Luo, Z; Pang, Y; Sheng, J1
Alejandre-Ramos, D; Bartolini, M; Bolognesi, ML; Fernández-Bolaños, JG; Lagunes, I; López, Ó; Maya, I; Monti, B; Padrón, JM; Peña-Altamira, LE; Roldán-Peña, JM1
Hiraka, Y; Manabe, T; Shimazaki, Y; Uesugi, M1

Other Studies

6 other study(ies) available for ebselen and tacrine

ArticleYear
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Synthesis and evaluation of multi-target-directed ligands against Alzheimer's disease based on the fusion of donepezil and ebselen.
    Journal of medicinal chemistry, 2013, Nov-27, Volume: 56, Issue:22

    Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Azoles; Butyrylcholinesterase; Chemistry Techniques, Synthetic; Cholinesterase Inhibitors; Donepezil; Electrophorus; Glutathione Peroxidase; Humans; Indans; Isoindoles; Kinetics; Ligands; Mice; Molecular Docking Simulation; Molecular Targeted Therapy; Organoselenium Compounds; Peptide Fragments; Peroxynitrous Acid; Piperidines; Protein Multimerization; Protein Structure, Secondary; Thioredoxin-Disulfide Reductase; Toxicity Tests, Acute

2013
Novel tacrine-ebselen hybrids with improved cholinesterase inhibitory, hydrogen peroxide and peroxynitrite scavenging activity.
    Bioorganic & medicinal chemistry letters, 2013, Dec-15, Volume: 23, Issue:24

    Topics: Acetylcholinesterase; Animals; Azoles; Binding Sites; Butyrylcholinesterase; Cell Line; Cell Survival; Cholinesterase Inhibitors; Free Radical Scavengers; Horses; Humans; Hydrogen Peroxide; Isoindoles; Kinetics; Molecular Docking Simulation; Organoselenium Compounds; Peroxynitrous Acid; Protein Binding; Protein Structure, Tertiary; Tacrine

2013
Synthesis and biological evaluation of a new series of ebselen derivatives as glutathione peroxidase (GPx) mimics and cholinesterase inhibitors against Alzheimer's disease.
    Bioorganic & medicinal chemistry, 2014, Feb-15, Volume: 22, Issue:4

    Topics: Acetylcholinesterase; Alzheimer Disease; Antioxidants; Azoles; Biocompatible Materials; Butyrylcholinesterase; Cholinesterase Inhibitors; Glutathione Peroxidase; Humans; Isoindoles; Organoselenium Compounds; Protein Binding

2014
New tacrine dimers with antioxidant linkers as dual drugs: Anti-Alzheimer's and antiproliferative agents.
    European journal of medicinal chemistry, 2017, Sep-29, Volume: 138

    Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Antineoplastic Agents; Antioxidants; Cell Line, Tumor; Cell Proliferation; Chalcogens; Cholinesterase Inhibitors; Dimerization; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Mice; Molecular Structure; Organoselenium Compounds; Peptide Fragments; Protein Aggregates; Structure-Activity Relationship; Tacrine

2017
Simultaneous analysis of esterase and transferase activities in cytosol proteins from the bovine retina by using microscale non-denaturing two-dimensional electrophoresis.
    Biochimica et biophysica acta, 2004, Jan-14, Volume: 1696, Issue:1

    Topics: Animals; Azoles; Cattle; Cytosol; Electrophoresis, Gel, Two-Dimensional; Esterases; Glutathione Transferase; Immunoblotting; Isoindoles; Organoselenium Compounds; Phosphoric Diester Hydrolases; Retina; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tacrine; Transferases

2004