ebselen and mechlorethamine

ebselen has been researched along with mechlorethamine in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (55.56)29.6817
2010's3 (33.33)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Bischoff, PL; Coelho, D; Dufour, P; Holl, V; Keyser, JF; Silbernagel, L; Waltzinger, C1
Boisvieux-Ulrich, E; Brenner, C; Breton, P; Daulon, S; Deniaud, A; Lemaire, C; Marano, F; Sourdeval, M; Taysse, L1
Karayilanoglu, T; Korkmaz, A; Kurt, B; Mollaoglu, H; Oter, S; Topal, T; Yaren, H1
Billack, B; Hardej, D1
Billack, B; Pino, MA1
Billack, B; Lulla, A; Młochowski, J; Piętka-Ottlik, M; Pino, MA; Sparavalo, O1
Billack, B; Pietka-Ottlik, M; Pino, MA1
Billack, B; Lulla, A; Reznik, S; Trombetta, L1
Billack, B; Cuffari, BJ; Palus, J; Piętka-Ottlik, M; Pino, MA; Tumu, HCR1

Other Studies

9 other study(ies) available for ebselen and mechlorethamine

ArticleYear
Prevention of nitrogen mustard-induced apoptosis in normal and transformed lymphocytes by ebselen.
    Biochemical pharmacology, 2000, Dec-01, Volume: 60, Issue:11

    Topics: Animals; Antioxidants; Apoptosis; Azoles; Cell Line, Transformed; Drug Interactions; Humans; Isoindoles; Lymphocytes; Mechlorethamine; Mice; Mice, Inbred BALB C; Organoselenium Compounds; Spleen

2000
Inhibition of caspase-dependent mitochondrial permeability transition protects airway epithelial cells against mustard-induced apoptosis.
    Apoptosis : an international journal on programmed cell death, 2006, Volume: 11, Issue:9

    Topics: Animals; Apoptosis; Azoles; Caspases; Cell Adhesion; Cell Membrane Permeability; Cells, Cultured; Cyclosporine; HeLa Cells; Humans; Isoindoles; Mechlorethamine; Melatonin; Mice; Mitochondria; Models, Biological; Multiprotein Complexes; Mustard Gas; Organoselenium Compounds; Proto-Oncogene Proteins c-bcl-2; Respiratory Mucosa; Tumor Suppressor Protein p53

2006
Lung toxicity of nitrogen mustard may be mediated by nitric oxide and peroxynitrite in rats.
    Research in veterinary science, 2007, Volume: 83, Issue:1

    Topics: Alkylating Agents; Animals; Antioxidants; Azoles; Guanidines; Isoindoles; Lung Diseases; Male; Mechlorethamine; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type II; Nitrites; Organoselenium Compounds; Peroxynitrous Acid; Rats; Rats, Wistar

2007
Ebselen protects brain, skin, lung and blood cells from mechlorethamine toxicity.
    Toxicology and industrial health, 2007, Volume: 23, Issue:4

    Topics: Animals; Astrocytes; Azoles; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Survival; Chemical Warfare Agents; Cytoprotection; Drug Evaluation; Epithelial Cells; Hippocampus; Humans; Isoindoles; Mechlorethamine; Microscopy; Neuroprotective Agents; Organoselenium Compounds; Pleura; Rats; Rats, Sprague-Dawley; T-Lymphocytes

2007
Reduction of vesicant toxicity by butylated hydroxyanisole in A-431 skin cells.
    Cutaneous and ocular toxicology, 2008, Volume: 27, Issue:3

    Topics: Antioxidants; Azoles; Buthionine Sulfoximine; Butylated Hydroxyanisole; Cell Line, Tumor; Chemical Warfare Agents; DNA Fragmentation; Epidermal Cells; Glutathione; Humans; Isoindoles; Mechlorethamine; Molecular Structure; Mustard Gas; Organoselenium Compounds

2008
Ebselen reduces the toxicity of mechlorethamine in A-431 cells via inhibition of apoptosis.
    Journal of biochemical and molecular toxicology, 2013, Volume: 27, Issue:6

    Topics: Antidotes; Antioxidants; Apoptosis; Ascorbic Acid; Azoles; Caspase 3; Caspase 9; Cell Line; Chemical Warfare Agents; Cytoprotection; Humans; Irritants; Isoindoles; Mechlorethamine; Organoselenium Compounds; Resveratrol; Stilbenes

2013
Selected ebselen analogs reduce mechlorethamine toxicity in vitro.
    Cutaneous and ocular toxicology, 2014, Volume: 33, Issue:1

    Topics: Antioxidants; Azoles; Cell Line, Tumor; Cell Survival; Humans; Isoindoles; Lipid Peroxidation; Malondialdehyde; Mechlorethamine; Microscopy, Phase-Contrast; Molecular Structure; Mustard Gas; Organoselenium Compounds; Skin; Structure-Activity Relationship

2014
Use of the mouse ear vesicant model to evaluate the effectiveness of ebselen as a countermeasure to the nitrogen mustard mechlorethamine.
    Journal of applied toxicology : JAT, 2014, Volume: 34, Issue:12

    Topics: Administration, Cutaneous; Animals; Azoles; Dose-Response Relationship, Drug; Ear; Edema; Irritants; Isoindoles; Male; Mechlorethamine; Mice; Organoselenium Compounds; Protective Agents; Skin; Skin Irritancy Tests

2014
Ebselen oxide attenuates mechlorethamine dermatotoxicity in the mouse ear vesicant model.
    Drug and chemical toxicology, 2020, Volume: 43, Issue:4

    Topics: Alkylating Agents; Animals; Apoptosis; Azoles; Cytoprotection; Ear; Irritants; Isoindoles; Mechlorethamine; Mice; Organoselenium Compounds; Skin

2020