ebselen and indomethacin

ebselen has been researched along with indomethacin in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19903 (20.00)18.7374
1990's6 (40.00)18.2507
2000's3 (20.00)29.6817
2010's2 (13.33)24.3611
2020's1 (6.67)2.80

Authors

AuthorsStudies
Abadie, C; Bernier, JL; Chalas, J; Galet, V; Hénichart, JP; Lesieur, D; Lindenbaum, A; Pfeiffer, B; Renaud de la Faverie, JF; Rochette, L1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Bast, A; Leurs, R; Timmerman, H1
Leyck, S; Parnham, MJ1
Akasaki, M; Kurebayashi, Y; Tabuchi, Y1
Kuhl, P; Leyck, S; Parnham, MJ; Schalkwijk, J; van den Berg, WB1
Tiegs, G; Wendel, A1
Gao, JX; Issekutz, AC2
Baran, H; Hornykiewicz, O; Lassmann, H; Vass, K1
Bubolz, AH; Gutterman, DD; Liu, Y; Newman, DK; Newman, PJ; Shi, Y1

Other Studies

15 other study(ies) available for ebselen and indomethacin

ArticleYear
Benzoselenazolinone derivatives designed to be glutathione peroxidase mimetics feature inhibition of cyclooxygenase/5-lipoxygenase pathways and anti-inflammatory activity.
    Journal of medicinal chemistry, 1994, Sep-02, Volume: 37, Issue:18

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Azoles; Cyclooxygenase Inhibitors; Glutathione Peroxidase; Hemolysis; Humans; In Vitro Techniques; Isoindoles; Lipid Peroxidation; Lipoxygenase Inhibitors; Male; Organoselenium Compounds; Rats; Rats, Wistar; Structure-Activity Relationship

1994
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Ebselen inhibits contractile responses of guinea-pig parenchymal lung strips.
    European journal of pharmacology, 1990, Apr-10, Volume: 179, Issue:1-2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Azoles; Catechols; Cyclooxygenase Inhibitors; Guinea Pigs; Histamine; Indomethacin; Isoindoles; Isoquinolines; Lung; Male; Masoprocol; Muscle Contraction; Muscle, Smooth; Organoselenium Compounds; Piperazines; Potassium Chloride; Selenium; Thiazoles

1990
Acute antiinflammatory and gastric effects of the seleno-organic compound ebselen.
    Agents and actions, 1990, Volume: 30, Issue:3-4

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Azoles; Diclofenac; Edema; Elapid Venoms; Female; Gastric Mucosa; Indomethacin; Isoindoles; Levamisole; Male; Organoselenium Compounds; Rats; Rats, Inbred Strains; Selenium

1990
Gastric cytoprotection by ebselen against the injury induced by necrotizing agents in rats.
    Arzneimittel-Forschung, 1989, Volume: 39, Issue:2

    Topics: Animals; Antioxidants; Azoles; Ethanol; Gastric Mucosa; Indomethacin; Isoindoles; Male; Necrosis; Organoselenium Compounds; Rats; Rats, Inbred Strains; Selenium; Stomach Ulcer

1989
Ebselen: a new approach to the inhibition of peroxide-dependent inflammation.
    International journal of tissue reactions, 1987, Volume: 9, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Azoles; Edema; Female; Indomethacin; Inflammation; Isoindoles; Leukotriene B4; Male; Organoselenium Compounds; Peroxides; Piroxicam; Rats; Rats, Inbred Strains; Selenium

1987
A novel biologically active seleno-organic compound--VI. Protection by ebselen (PZ 51) against galactosamine/endotoxin-induced hepatitis in mice.
    Biochemical pharmacology, 1986, Jul-01, Volume: 35, Issue:13

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Azoles; Chemical and Drug Induced Liver Injury; Dexamethasone; Diethylcarbamazine; Endotoxins; Galactosamine; Glutathione; Glutathione Disulfide; Hepatitis, Animal; Ibuprofen; Indomethacin; Isoindoles; L-Iditol 2-Dehydrogenase; Male; Mice; Organoselenium Compounds; Selenium; Time Factors

1986
The effect of ebselen on T-lymphocyte migration to arthritic joints and dermal inflammatory reactions in the rat.
    International journal of immunopharmacology, 1994, Volume: 16, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Azoles; Chemotaxis, Leukocyte; Cytokines; Dermatitis, Contact; Hypersensitivity, Delayed; Indicators and Reagents; Indomethacin; Injections, Intradermal; Isoindoles; Joints; Lymph Nodes; Male; Organoselenium Compounds; Rats; Rats, Inbred Lew; Skin; Spleen; T-Lymphocytes

1994
The cyclooxygenase and lipoxygenase inhibitor BW755C protects rats against kainic acid-induced seizures and neurotoxicity.
    Brain research, 1994, May-23, Volume: 646, Issue:2

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Azoles; Brain; Choline O-Acetyltransferase; Cyclooxygenase Inhibitors; Glutamate Decarboxylase; Ibuprofen; Indomethacin; Isoindoles; Kainic Acid; Lipoxygenase Inhibitors; Male; Organ Specificity; Organoselenium Compounds; Rats; Rats, Sprague-Dawley; Seizures

1994
The effect of ebselen on polymorphonuclear leukocyte migration to joints in rats with adjuvant arthritis.
    International journal of immunopharmacology, 1993, Volume: 15, Issue:7

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Arthritis, Experimental; Azoles; Cell Movement; Disease Models, Animal; Dose-Response Relationship, Drug; Indomethacin; Inflammation; Isoindoles; Joints; Male; Neutrophils; Organoselenium Compounds; Proteins; Rats; Rats, Inbred Strains; Skin

1993
Peroxynitrite reduces the endothelium-derived hyperpolarizing factor component of coronary flow-mediated dilation in PECAM-1-knockout mice.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2006, Volume: 290, Issue:1

    Topics: Animals; Azoles; Biological Factors; Coronary Vessels; Gene Deletion; Hydrogen Peroxide; Indomethacin; Isoindoles; Male; Mice; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide; Organoselenium Compounds; Peroxynitrous Acid; Platelet Endothelial Cell Adhesion Molecule-1; Prostaglandins; Tyrosine; Vasodilation

2006