ebselen and glutamic acid

ebselen has been researched along with glutamic acid in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's15 (75.00)29.6817
2010's3 (15.00)24.3611
2020's2 (10.00)2.80

Authors

AuthorsStudies
Boeck, CR; Porciúncula, LO; Rocha, JB; Souza, DO; Vendite, D1
Nogueira, CW; Rocha, JB; Rotta, LN; Souza, DO; Zeni, G1
Brusque, AM; Dahm, KC; Farina, M; Frizzo, ME; Rocha, JB; Schwalm, FD; Souza, DO; Zeni, G1
Dietrich, MO; Farina, M; Frizzo, ME; Rocha, JB; Schwalm, FD; Soares, FA; Souza, DO; Zeni, G1
Borges, VC; Nogueira, CW; Rocha, JB; Zeni, G1
Franco, J; Moretto, MB; Nogueira, CW; Posser, T; Rocha, JB; Zeni, G1
Braga, AL; Centurião, FB; Corte, CL; Emanuelli, T; Paixão, MW; Rocha, JB; Zeni, G1
Pourbakht, A; Sakamoto, T; Suzuki, M; Yamasoba, T1
Boff, B; Funchal, C; Gottfried, C; Moretto, MB; Pureur, RP; Rocha, JB; Santos, AQ; Souza, DO; Wofchuk, S; Zeni, G1
Hu, HT; Liu, Y; Liu, ZH; Qian, YH; Tan, QR; Xu, JH; Zhang, ZJ1
Godinho, G; Moretto, MB; Nogueira, CW; Rocha, JB; Roessler, TM; Souza, DO; Thomazi, AP; Wofchuk, S1
González, A; Pariente, JA; Salazar, M; Salido, GM1
Boeck, CR; Ghisleni, G; Mioranzza, S; Porciúncula, LO; Rocha, JB; Souza, DO1
Coelho, IS; Dafre, AL; Franco, JL; Meotti, FC; Rocha, JB; Santos, AR1
Aschner, M; Barbosa, NB; Burger, ME; Farina, M; Nogueira, CW; Puntel, RL; Rocha, JB; Roos, DH; Santos, MM; Souza, DO1
Fujisawa, H; Koizumi, H; Shirao, S; Suehiro, E; Suzuki, M1
Bastos, LL; Dalla Corte, CL; Dobrachinski, F; Rocha, JB; Soares, FA1
Berrington, A; Churchill, GC; Cowen, PJ; Emir, UE; Godlewska, BR; Hashimoto, T; Masaki, C; Sharpley, AL; Singh, N; Vasudevan, SR1
Bordoloi, J; Cash, D; Eykyn, T; Hader, S; Moses, N; Mota, F; Sementa, T; Singh, N; Taddei, C; Turkheimer, F; Veronese, M1
Chen, Y; Mao, H1

Reviews

1 review(s) available for ebselen and glutamic acid

ArticleYear
Noise-Induced Hearing Loss: Updates on Molecular Targets and Potential Interventions.
    Neural plasticity, 2021, Volume: 2021

    Topics: Animals; Autophagy; Calcium; Clinical Trials, Phase II as Topic; DNA Repair; Drugs, Investigational; Energy Metabolism; Gap Junctions; Glutamic Acid; Hair Cells, Auditory; Hearing Loss, Noise-Induced; Humans; Inflammation; Isoindoles; Nanoparticles; Organoselenium Compounds; Oxidative Stress; Potassium Channels; Stereocilia

2021

Trials

1 trial(s) available for ebselen and glutamic acid

ArticleYear
Effects of the potential lithium-mimetic, ebselen, on brain neurochemistry: a magnetic resonance spectroscopy study at 7 tesla.
    Psychopharmacology, 2016, Volume: 233, Issue:6

    Topics: Adult; Azoles; Cross-Over Studies; Double-Blind Method; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Inositol; Isoindoles; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Occipital Lobe; Organoselenium Compounds; Young Adult

2016

Other Studies

18 other study(ies) available for ebselen and glutamic acid

ArticleYear
Ebselen prevents excitotoxicity provoked by glutamate in rat cerebellar granule neurons.
    Neuroscience letters, 2001, Feb-23, Volume: 299, Issue:3

    Topics: Animals; Animals, Newborn; Antioxidants; Azoles; Cell Survival; Cells, Cultured; Cerebellar Cortex; Dose-Response Relationship, Drug; Glutamic Acid; Isoindoles; Lipid Peroxidation; Nerve Degeneration; Neurodegenerative Diseases; Neuroprotective Agents; Neurotoxins; Organoselenium Compounds; Rats; Rats, Wistar

2001
Exposure to ebselen changes glutamate uptake and release by rat brain synaptosomes.
    Neurochemical research, 2002, Volume: 27, Issue:4

    Topics: Animals; Azoles; Biological Transport; Brain; Glutamic Acid; Isoindoles; Male; Neuroprotective Agents; Organoselenium Compounds; Potassium; Rats; Rats, Wistar; Synaptic Vesicles; Synaptosomes

2002
Methylmercury increases glutamate release from brain synaptosomes and glutamate uptake by cortical slices from suckling rat pups: modulatory effect of ebselen.
    Toxicological sciences : an official journal of the Society of Toxicology, 2003, Volume: 73, Issue:1

    Topics: Aging; Animals; Animals, Suckling; Azoles; Brain Chemistry; Cerebral Cortex; Glutamic Acid; In Vitro Techniques; Isoindoles; L-Lactate Dehydrogenase; Methylmercury Compounds; Nerve Tissue Proteins; Neuroprotective Agents; Organoselenium Compounds; Presynaptic Terminals; Rats; Rats, Wistar; Synaptosomes

2003
Ebselen protects against methylmercury-induced inhibition of glutamate uptake by cortical slices from adult mice.
    Toxicology letters, 2003, Oct-15, Volume: 144, Issue:3

    Topics: Animals; Antioxidants; Astrocytes; Azoles; Catalase; Cerebral Cortex; Glutamic Acid; Glutathione Peroxidase; Hydrogen Peroxide; Isoindoles; Lipid Peroxidation; Male; Methylmercury Compounds; Mice; Organoselenium Compounds

2003
Organochalcogens affect the glutamatergic neurotransmission in human platelets.
    Neurochemical research, 2004, Volume: 29, Issue:8

    Topics: Azoles; Benzene Derivatives; Blood Platelets; Glutamic Acid; Humans; Isoindoles; Neuroprotective Agents; Organometallic Compounds; Organoselenium Compounds; Synaptic Transmission

2004
Ebselen protects Ca2+ influx blockage but does not protect glutamate uptake inhibition caused by Hg2+.
    Neurochemical research, 2004, Volume: 29, Issue:10

    Topics: Animals; Azoles; Calcium Signaling; Glutamic Acid; Isoindoles; Male; Mercury; Organoselenium Compounds; Rats; Rats, Wistar; Synaptosomes

2004
Effect of ebselen and organochalcogenides on excitotoxicity induced by glutamate in isolated chick retina.
    Brain research, 2005, Mar-28, Volume: 1039, Issue:1-2

    Topics: Animals; Azoles; Benzene Derivatives; Calcium; Calcium Channels; Chalcogens; Chick Embryo; Dose-Response Relationship, Drug; Glutamic Acid; Isoindoles; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Organometallic Compounds; Organoselenium Compounds; Retina; Tellurium; Tetrazolium Salts; Thiazoles

2005
Ebselen prevents noise-induced excitotoxicity and temporary threshold shift.
    Neuroscience letters, 2005, Jun-03, Volume: 380, Issue:3

    Topics: Animals; Auditory Threshold; Azoles; Cochlear Nerve; Dendrites; Disease Models, Animal; Evoked Potentials, Auditory, Brain Stem; Excitatory Amino Acid Antagonists; Free Radical Scavengers; Free Radicals; Glutamic Acid; Guinea Pigs; Hair Cells, Auditory; Hearing Loss, Sensorineural; Isoindoles; Male; Nerve Degeneration; Neurons, Afferent; Neuroprotective Agents; Noise; Organoselenium Compounds; Oxidative Stress; Synaptic Transmission; Treatment Outcome

2005
Ebselen protects glutamate uptake inhibition caused by methyl mercury but does not by Hg2+.
    Toxicology, 2005, Oct-15, Volume: 214, Issue:1-2

    Topics: Animals; Azoles; Benzene Derivatives; Cell Survival; Cerebral Cortex; Glutamic Acid; In Vitro Techniques; Isoindoles; Mercuric Chloride; Methylmercury Compounds; Neuroprotective Agents; Organoselenium Compounds; Rats; Rats, Wistar

2005
Neuroprotective effects of ebselen are associated with the regulation of Bcl-2 and Bax proteins in cultured mouse cortical neurons.
    Neuroscience letters, 2006, May-22, Volume: 399, Issue:3

    Topics: Analysis of Variance; Animals; Apoptosis; Azoles; bcl-2-Associated X Protein; Cell Count; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Gene Expression Regulation, Developmental; Glutamic Acid; Isoindoles; Mice; Neurons; Neuroprotective Agents; Organoselenium Compounds; Proto-Oncogene Proteins c-bcl-2; Time Factors

2006
Ebselen and diorganylchalcogenides decrease in vitro glutamate uptake by rat brain slices: prevention by DTT and GSH.
    Toxicology in vitro : an international journal published in association with BIBRA, 2007, Volume: 21, Issue:4

    Topics: Aging; Animals; Antidotes; Azoles; Benzene Derivatives; Brain; Brain Chemistry; Cerebral Cortex; Chalcogens; Dithiothreitol; Glutamic Acid; Glutathione; In Vitro Techniques; Isoindoles; Male; Organometallic Compounds; Organoselenium Compounds; Rats; Rats, Wistar

2007
Ebselen increases cytosolic free Ca2+ concentration, stimulates glutamate release and increases GFAP content in rat hippocampal astrocytes.
    Toxicology, 2008, Feb-28, Volume: 244, Issue:2-3

    Topics: Animals; Animals, Newborn; Astrocytes; Azoles; Calcium; Cell Survival; Cells, Cultured; Cytosol; Endoplasmic Reticulum; Glial Fibrillary Acidic Protein; Glutamic Acid; Hippocampus; Immunohistochemistry; Isoindoles; L-Lactate Dehydrogenase; Neuroprotective Agents; Organoselenium Compounds; Rats; Rats, Wistar

2008
Selenium compounds counteract the stimulation of ecto-nucleotidase activities in rat cultured cerebellar granule cells: putative correlation with neuroprotective effects.
    Brain research, 2008, Jul-24, Volume: 1221

    Topics: Adenosine Triphosphatases; Animals; Antioxidants; Azoles; Brain Damage, Chronic; Cells, Cultured; Cerebellum; Chromans; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ethylmaleimide; Glutamic Acid; Isoindoles; Nerve Degeneration; Neurons; Neuroprotective Agents; Nucleotides; Organoselenium Compounds; Oxidative Stress; Rats; Selenium

2008
Redox modulation at the peripheral site alters nociceptive transmission in vivo.
    Clinical and experimental pharmacology & physiology, 2009, Volume: 36, Issue:3

    Topics: Alkylating Agents; Analgesics; Animals; Azoles; Behavior, Animal; Buthionine Sulfoximine; Disease Models, Animal; Dithiothreitol; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Female; Glutamate-Cysteine Ligase; Glutamic Acid; Glutathione; Iodoacetates; Isoindoles; Mice; Organoselenium Compounds; Oxidation-Reduction; Pain; Receptors, N-Methyl-D-Aspartate; Reducing Agents; Signal Transduction; Sulfhydryl Compounds

2009
Guanosine and synthetic organoselenium compounds modulate methylmercury-induced oxidative stress in rat brain cortical slices: involvement of oxidative stress and glutamatergic system.
    Toxicology in vitro : an international journal published in association with BIBRA, 2009, Volume: 23, Issue:2

    Topics: Animals; Azoles; Benzene Derivatives; Brain; Cell Survival; Dizocilpine Maleate; Drug Combinations; Glutamic Acid; Guanosine; Isoindoles; L-Lactate Dehydrogenase; Male; Methylmercury Compounds; Organ Culture Techniques; Organoselenium Compounds; Oxidative Stress; Rats; Rats, Wistar

2009
Neuroprotective effects of ebselen following forebrain ischemia: involvement of glutamate and nitric oxide.
    Neurologia medico-chirurgica, 2011, Volume: 51, Issue:5

    Topics: Animals; Azoles; Brain Ischemia; CA1 Region, Hippocampal; Cerebrovascular Circulation; Disease Models, Animal; Enzyme Inhibitors; Glutamic Acid; Isoindoles; Male; Microdialysis; Neuroprotective Agents; Neurotransmitter Agents; Nitric Oxide; Nitric Oxide Synthase; Organoselenium Compounds; Presynaptic Terminals; Prosencephalon; Random Allocation; Rats; Rats, Wistar

2011
The combination of organoselenium compounds and guanosine prevents glutamate-induced oxidative stress in different regions of rat brains.
    Brain research, 2012, Jan-09, Volume: 1430

    Topics: Animals; Antioxidants; Azoles; Benzene Derivatives; Brain; Brain Diseases, Metabolic; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Glutamic Acid; Guanosine; Isoindoles; Male; Neuroprotective Agents; Neurotoxins; Organ Culture Techniques; Organoselenium Compounds; Oxidative Stress; Rats; Rats, Wistar

2012
Investigating the effects of ebselen, a potential new lithium mimetic, on glutamate transmission.
    Synapse (New York, N.Y.), 2020, Volume: 74, Issue:7

    Topics: Animals; Azoles; Brain; Glutamic Acid; Isoindoles; Organoselenium Compounds; Positron-Emission Tomography; Protein Binding; Psychotropic Drugs; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Synaptic Transmission

2020