ebselen and cysteine

ebselen has been researched along with cysteine in 16 studies

Research

Studies (16)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	4 (25.00)	29.6817
2010's	8 (50.00)	24.3611
2020's	4 (25.00)	2.80

Authors

Authors	Studies
Aizenman, E; Du, S; Herin, GA	1
Borges, VC; Nogueira, CW; Rocha, JB; Zeni, G	1
Billack, B; Lau-Cam, C; Santoro, M	1
Freewan, M; Raftery, MJ; Sempértegui Plaza, TS; Stocker, R; Terentis, AC; Thomas, SR	1
Han, SG; Jin, BS; Lee, SJ; Lee, WK; Ryoo, SW; Suh, SW; Yu, YG	1
Favrot, L; Lajiness, DH; Ronning, DR	1
Borges, CR; Faigel, DO; Hanavan, PD; Ho, TH; Katchman, BA; Lake, DF; Ma, CT; Meurice, N; Petit, JL; Sergienko, EA	1
Huang, K; Xu, H; Zhou, J	1
de la Casa-Resino, I; Gonzalez, A; Izquierdo-Alvarez, A; Martinez-Ruiz, A; Perez-Lopez, M; Portilla, JC; Salido, GM; Santofimia-Castaño, P	1
Chen, C; Ge, Y; Liu, Y; Su, JP; Wang, WM; Xiang, Y; Yang, KW; Zhang, Y	1
Antonyuk, SV; Banci, L; Barbieri, L; Capper, MJ; Hasnain, SS; Luchinat, E; McAlary, L; Mercatelli, E; O'Neill, PM; Wright, GSA; Yerbury, JJ	1
Brem, J; de Munnik, M; Lang, PA; Langley, GW; Lohans, CT; Malla, TR; Schofield, CJ; Tumber, A	1
Atack, JR; Bax, BD; Fenn, GD; Waller-Evans, H	1
Døskeland, A; Gasparik, N; Haavik, J; Hritz, J; Jung-Kc, K; Kleppe, R; Martinez, A; Norton, WHJ; Pandey, S; Patil, S; Vecchia, ED; Waløen, K	1
Amporndanai, K; Jin, Z; Liu, ZJ; Meng, X; O'Neill, PM; Rao, Z; Rogers, M; Samar Hasnain, S; Shang, W; Yang, H; Zhang, L; Zhao, Y	1
Jiang, J; Li, Y; Peng, C; Tian, Q; Wang, Z; Wu, P; Yin, H; Zeng, H; Zhang, Y; Zhong, D; Zhou, J	1

Reviews

1 review(s) available for ebselen and cysteine

Article	Year
Organoselenium Small Molecules and Chromium(III) Complexes for Intervention in Chronic Low-grade Inflammation and Type 2 Diabetes. Current topics in medicinal chemistry, 2016, Volume: 16, Issue:8 Topics: Anti-Inflammatory Agents, Non-Steroidal; Azoles; Chromium Compounds; Cysteine; Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Inflammation; Isoindoles; Obesity; Organometallic Compounds; Organoselenium Compounds; Picolinic Acids; Small Molecule Libraries	2016

Article

Year

Organoselenium Small Molecules and Chromium(III) Complexes for Intervention in Chronic Low-grade Inflammation and Type 2 Diabetes.

Current topics in medicinal chemistry, 2016, Volume: 16, Issue:8

Topics: Anti-Inflammatory Agents, Non-Steroidal; Azoles; Chromium Compounds; Cysteine; Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Inflammation; Isoindoles; Obesity; Organometallic Compounds; Organoselenium Compounds; Picolinic Acids; Small Molecule Libraries

2016

Other Studies

15 other study(ies) available for ebselen and cysteine

Article	Year
The neuroprotective agent ebselen modifies NMDA receptor function via the redox modulatory site. Journal of neurochemistry, 2001, Volume: 78, Issue:6 Topics: Animals; Antioxidants; Azoles; Cells, Cultured; Cerebral Cortex; CHO Cells; Cricetinae; Cysteine; Isoindoles; N-Methylaspartate; Neurons; Neuroprotective Agents; Neurotoxins; Organoselenium Compounds; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic	2001
Organochalcogens effects on delta-aminolevulinate dehydratase activity from human erythrocytic cells in vitro. Toxicology, 2003, Sep-30, Volume: 191, Issue:2-3 Topics: Antioxidants; Azoles; Benzene Derivatives; Cysteine; Disulfides; Dithiothreitol; Drug Interactions; Erythrocytes; Glutathione Transferase; Humans; Isoindoles; Organometallic Compounds; Organoselenium Compounds; Porphobilinogen Synthase; Zinc	2003
Growth inhibitory action of ebselen on fluconazole-resistant Candida albicans: role of the plasma membrane H+-ATPase. Microbial drug resistance (Larchmont, N.Y.), 2009, Volume: 15, Issue:2 Topics: Amphotericin B; Antifungal Agents; Azoles; Candida albicans; Cyclooxygenase Inhibitors; Cysteine; Drug Resistance, Fungal; Fluconazole; Isoindoles; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Organoselenium Compounds; Proton-Translocating ATPases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins	2009
The selenazal drug ebselen potently inhibits indoleamine 2,3-dioxygenase by targeting enzyme cysteine residues. Biochemistry, 2010, Jan-26, Volume: 49, Issue:3 Topics: Azoles; Binding Sites; Catalysis; Circular Dichroism; Cysteine; Enzyme Inhibitors; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Isoindoles; Kinetics; Organoselenium Compounds; Protein Conformation; Spectrum Analysis, Raman	2010
Inhibitory mechanism of novel inhibitors of UDP-N-acetylglucosamine enolpyruvyl transferase from Haemophilus influenzae. Journal of microbiology and biotechnology, 2009, Volume: 19, Issue:12 Topics: Alkyl and Aryl Transferases; Antioxidants; Azoles; Catalytic Domain; Cell Wall; Cysteine; Escherichia coli; Fungicides, Industrial; Gram-Negative Bacterial Infections; Haemophilus influenzae; Humans; Isoindoles; Organoselenium Compounds; Preservatives, Pharmaceutical; Protein Conformation; Pseudomonas aeruginosa; Salmonella typhimurium; Thimerosal; Thiram	2009
Inactivation of the Mycobacterium tuberculosis antigen 85 complex by covalent, allosteric inhibitors. The Journal of biological chemistry, 2014, Sep-05, Volume: 289, Issue:36 Topics: Acyltransferases; Allosteric Regulation; Anti-Inflammatory Agents, Non-Steroidal; Antigens, Bacterial; Azoles; Biocatalysis; Catalytic Domain; Chloromercuribenzoates; Crystallography, X-Ray; Cysteine; Enzyme Activation; Enzyme Inhibitors; Hydrogen Bonding; Iodoacetamide; Isoindoles; Models, Molecular; Molecular Structure; Mutation; Organoselenium Compounds; Protein Conformation; Protein Structure, Secondary	2014
Ebselen inhibits QSOX1 enzymatic activity and suppresses invasion of pancreatic and renal cancer cell lines. Oncotarget, 2015, Jul-30, Volume: 6, Issue:21 Topics: Amino Acid Sequence; Animals; Anti-Inflammatory Agents, Non-Steroidal; Azoles; Blotting, Western; Carcinoma, Renal Cell; Cell Line, Tumor; Cell Proliferation; Cysteine; Humans; Isoindoles; Kidney Neoplasms; Mice, Nude; Molecular Sequence Data; Molecular Structure; Neoplasm Invasiveness; Organoselenium Compounds; Oxidoreductases Acting on Sulfur Group Donors; Pancreatic Neoplasms; RNA Interference; Sequence Homology, Amino Acid; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tumor Burden; Xenograft Model Antitumor Assays	2015
Ebselen alters cellular oxidative status and induces endoplasmic reticulum stress in rat hippocampal astrocytes. Toxicology, 2016, 05-16, Volume: 357-358 Topics: Animals; Antioxidants; Astrocytes; Azoles; Calcium; Cysteine; Dose-Response Relationship, Drug; Endoplasmic Reticulum Stress; Glial Fibrillary Acidic Protein; Glutathione Transferase; Hippocampus; Isoindoles; Malondialdehyde; Mitochondria; Mitogen-Activated Protein Kinases; Organoselenium Compounds; Oxidative Stress; Phosphorylation; Rats; Rats, Wistar; Reactive Oxygen Species	2016
A protein structure-guided covalent scaffold selectively targets the B1 and B2 subclass metallo-β-lactamases. Chemical communications (Cambridge, England), 2018, May-08, Volume: 54, Issue:38 Topics: Amino Acid Sequence; Azoles; beta-Lactamase Inhibitors; beta-Lactamases; Catalytic Domain; Cysteine; Escherichia coli; Fluorescent Dyes; Isoindoles; Lysine; Organoselenium Compounds; Rhodamines	2018
The cysteine-reactive small molecule ebselen facilitates effective SOD1 maturation. Nature communications, 2018, 04-27, Volume: 9, Issue:1 Topics: Amyotrophic Lateral Sclerosis; Antioxidants; Asthma; Azoles; Crystallography, X-Ray; Cysteine; Disulfides; Edaravone; HEK293 Cells; Humans; Isoindoles; Molecular Chaperones; Mutation; Nuclear Magnetic Resonance, Biomolecular; Organoselenium Compounds; Protein Binding; Protein Folding; Protein Multimerization; Protein Stability; Superoxide Dismutase-1	2018
Targeting the Mycobacterium tuberculosis transpeptidase Ldt Chemical communications (Cambridge, England), 2019, Aug-22, Volume: 55, Issue:69 Topics: Antitubercular Agents; Azoles; Benzene Derivatives; Cysteine; Enzyme Inhibitors; Humans; Isoindoles; Molecular Docking Simulation; Mycobacterium tuberculosis; Organoselenium Compounds; Peptidyl Transferases; Tuberculosis	2019
Crystallization and structure of ebselen bound to Cys141 of human inositol monophosphatase. Acta crystallographica. Section F, Structural biology communications, 2020, Oct-01, Volume: 76, Issue:Pt 10 Topics: Antioxidants; Azoles; Crystallography, X-Ray; Cysteine; Humans; Isoindoles; Organoselenium Compounds; Protein Binding; Protein Conformation; Protein Domains; Ubiquitin-Protein Ligases	2020
Cysteine Modification by Ebselen Reduces the Stability and Cellular Levels of 14-3-3 Proteins. Molecular pharmacology, 2021, Volume: 100, Issue:2 Topics: 14-3-3 Proteins; Animals; Binding Sites; Brain; Cell Line; Circular Dichroism; Cysteine; Down-Regulation; Female; Humans; Isoindoles; Male; Models, Molecular; Mutagenesis, Site-Directed; Organoselenium Compounds; Protein Binding; Protein Conformation; Protein Stability; Tyrosine 3-Monooxygenase; Zebrafish; Zebrafish Proteins	2021
Inhibition mechanism of SARS-CoV-2 main protease by ebselen and its derivatives. Nature communications, 2021, 05-24, Volume: 12, Issue:1 Topics: Antiviral Agents; Azoles; Catalytic Domain; Coronavirus 3C Proteases; Crystallography, X-Ray; Cysteine; Hydrolysis; Isoindoles; Models, Molecular; Organoselenium Compounds; Protease Inhibitors; Reference Standards; Salicylanilides; SARS-CoV-2; Selenium	2021
Investigating the Metabolic Mechanisms of Butaselen, An Ebselen Analog. Current drug metabolism, 2022, Volume: 23, Issue:11 Topics: Cysteine; Humans; Organoselenium Compounds; Serum Albumin	2022