ebselen and ascorbic acid

ebselen has been researched along with ascorbic acid in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.76)18.7374
1990's2 (9.52)18.2507
2000's13 (61.90)29.6817
2010's5 (23.81)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cavaleiro, JA; Fernandes, E; Gomes, A; Lima, JL; Pinto, DC; Santos, CM; Silva, AM1
Cavaleiro, JA; Couto, D; Fernandes, E; Figueiredo, AG; Freitas, M; Gomes, A; Lima, JL; Neuwirth, O; Pinto, DC; Ribeiro, D; Seixas, RS; Silva, AM; Tomé, AC1
Cavaleiro, JA; Fernandes, E; Freitas, M; Gomes, A; Ribeiro, D; Santos, CM; Silva, AM1
Negm, A; Shaaban, S; Sobh, MA; Wessjohann, LA1
Ashmawy, AM; Negm, A; Shaaban, S; Wessjohann, LA1
Narayanaswami, V; Sies, H1
Hayashi, M; Slater, TF1
Boireau, A; Bordier, F; Coimbra, M; Dubedat, P; Imperato, A; Meunier, M; Moussaoui, S1
Green, KN; Peers, C1
Bouhafs, RK; Jarstrand, C1
Blasiak, J; Drzewoski, J; Gloc, E; Pertynski, T; Skórski, T; Wozniak, K; Zadrozny, M1
Braga, AL; Emanuelli, T; Lobato, LP; Paixão, MW; Perottoni, J; Rocha, JB; Rodrigues, OE; Zeni, G1
Holmgren, A; Zhao, R1
Exner, M; Gmeiner, B; Hartmann, B; Hermann, M; Hofbauer, R; Kapiotis, S1
Dehnade, F; Li, WQ; Liacini, A; Qureshi, HY; Zafarullah, M1
Chaston, TB; Richardson, DR; Watts, RN; Yuan, J1
Barbosa, NB; Nogueira, CW; Perottoni, J; Rocha, JB; Wondracek, DC; Zeni, G1
Ardais, AP; Nogueira, CW; Santos, FW1
Brown, GC; Brown, RD; Burke, GA1
Billack, B; Lulla, A; Młochowski, J; Piętka-Ottlik, M; Pino, MA; Sparavalo, O1
Chai, C; Chen, H; Chen, X; Deng, F; Du, H; Gao, J; Lu, J; Peng, Y; Tang, S; Zhang, H; Zuo, X1

Other Studies

21 other study(ies) available for ebselen and ascorbic acid

ArticleYear
2-Styrylchromones: novel strong scavengers of reactive oxygen and nitrogen species.
    Bioorganic & medicinal chemistry, 2007, Sep-15, Volume: 15, Issue:18

    Topics: Antioxidants; Chromones; Free Radical Scavengers; Free Radicals; Reactive Nitrogen Species; Reactive Oxygen Species; Styrenes

2007
Synthesis and antioxidant properties of new chromone derivatives.
    Bioorganic & medicinal chemistry, 2009, Oct-15, Volume: 17, Issue:20

    Topics: Antioxidants; Chromones; Magnetic Resonance Spectroscopy; Mass Spectrometry; Methylation; Reactive Nitrogen Species; Reactive Oxygen Species

2009
2,3-diarylxanthones as strong scavengers of reactive oxygen and nitrogen species: a structure-activity relationship study.
    Bioorganic & medicinal chemistry, 2010, Sep-15, Volume: 18, Issue:18

    Topics: Free Radical Scavengers; Hydrogen Peroxide; Hypochlorous Acid; Nitric Oxide; Peroxides; Peroxynitrous Acid; Reactive Nitrogen Species; Reactive Oxygen Species; Singlet Oxygen; Structure-Activity Relationship; Superoxides; Xanthones

2010
Organoselenocyanates and symmetrical diselenides redox modulators: Design, synthesis and biological evaluation.
    European journal of medicinal chemistry, 2015, Jun-05, Volume: 97

    Topics: Anti-Infective Agents; Antineoplastic Agents; Antioxidants; Carboxylic Acids; Cell Survival; Cyanates; Drug Design; Hep G2 Cells; Humans; Organoselenium Compounds; Oxidation-Reduction; Selenium Compounds

2015
Synthesis and biochemical studies of novel organic selenides with increased selectivity for hepatocellular carcinoma and breast adenocarcinoma.
    European journal of medicinal chemistry, 2019, Oct-01, Volume: 179

    Topics: Antineoplastic Agents; Antioxidants; Biphenyl Compounds; Breast Neoplasms; Carcinoma, Hepatocellular; Cell Line; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Hep G2 Cells; Humans; Liver Neoplasms; MCF-7 Cells; Molecular Structure; Organoselenium Compounds; Picrates; Structure-Activity Relationship

2019
Antioxidant activity of ebselen and related selenoorganic compounds in microsomal lipid peroxidation.
    Free radical research communications, 1990, Volume: 10, Issue:4-5

    Topics: Adenosine Diphosphate; Animals; Antioxidants; Ascorbic Acid; Azoles; Intracellular Membranes; Iron; Isoindoles; Kinetics; Lipid Peroxidation; Luminescent Measurements; Male; Microsomes; Organoselenium Compounds; Rats; Rats, Inbred Strains; Selenium; Thiobarbiturates; Vitamin E

1990
Inhibitory effects of ebselen on lipid peroxidation in rat liver microsomes.
    Free radical research communications, 1986, Volume: 2, Issue:3

    Topics: Adenosine Diphosphate; Animals; Antioxidants; Ascorbic Acid; Azoles; Carbon Tetrachloride; In Vitro Techniques; Iron; Isoindoles; Lipid Peroxides; Male; Malondialdehyde; Microsomes, Liver; Organoselenium Compounds; Oxygen Consumption; Rats; Selenium

1986
Effects of ebselen, a glutathione peroxidase mimic, in several models of mitochondrial dysfunction.
    Annals of the New York Academy of Sciences, 1999, Volume: 893

    Topics: Animals; Antioxidants; Ascorbic Acid; Azoles; Ferrous Compounds; Glutathione Peroxidase; Isoindoles; Lipid Peroxidation; Mitochondria, Liver; Mitochondrial Swelling; Organoselenium Compounds; Rats

1999
Divergent pathways account for two distinct effects of amyloid beta peptides on exocytosis and Ca(2+) currents: involvement of ROS and NF-kappaB.
    Journal of neurochemistry, 2002, Volume: 81, Issue:5

    Topics: Amyloid beta-Peptides; Animals; Antioxidants; Ascorbic Acid; Azoles; Cadmium; Calcium; Calcium Channels, L-Type; Catecholamines; Enzyme Inhibitors; Exocytosis; Fluorescent Antibody Technique; Indoles; Isoindoles; Maleimides; Melatonin; NF-kappa B; Organoselenium Compounds; Patch-Clamp Techniques; PC12 Cells; Peptide Fragments; Peptides; Rats; Reactive Oxygen Species; Signal Transduction; Sulfasalazine

2002
Effects of antioxidants on surfactant peroxidation by stimulated human polymorphonuclear leukocytes.
    Free radical research, 2002, Volume: 36, Issue:7

    Topics: Animals; Antioxidants; Ascorbic Acid; Azoles; Biological Products; Humans; In Vitro Techniques; Isoindoles; Lipid Peroxidation; Malondialdehyde; Melatonin; Neutrophil Activation; Neutrophils; Nitroblue Tetrazolium; Organoselenium Compounds; Oxidation-Reduction; Phagocytes; Phospholipids; Pulmonary Surfactants; Reactive Oxygen Species; Superoxide Dismutase; Swine; Vitamin E

2002
Free radical scavengers can differentially modulate the genotoxicity of amsacrine in normal and cancer cells.
    Mutation research, 2003, Feb-05, Volume: 535, Issue:1

    Topics: Adult; Amifostine; Amsacrine; Animals; Ascorbic Acid; Azoles; Cell Line, Transformed; Comet Assay; Cyclic N-Oxides; DNA Damage; DNA Repair; Dose-Response Relationship, Drug; Free Radical Scavengers; HL-60 Cells; Humans; In Vitro Techniques; Isoindoles; Lymphocytes; Male; Mice; Mutagens; Nitrogen Oxides; Organoselenium Compounds

2003
Renal and hepatic ALA-D activity and selected oxidative stress parameters of rats exposed to inorganic mercury and organoselenium compounds.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2004, Volume: 42, Issue:1

    Topics: Animals; Antioxidants; Ascorbic Acid; Azoles; Glutathione; Isoindoles; Kidney; Liver; Male; Mercury; Organoselenium Compounds; Oxidative Stress; Peroxidases; Porphobilinogen Synthase; Rats; Rats, Wistar; Sulfhydryl Compounds; Thiobarbituric Acid Reactive Substances

2004
Ebselen is a dehydroascorbate reductase mimic, facilitating the recycling of ascorbate via mammalian thioredoxin systems.
    Antioxidants & redox signaling, 2004, Volume: 6, Issue:1

    Topics: Animals; Antioxidants; Ascorbic Acid; Azoles; Cattle; Dehydroascorbic Acid; Humans; Hydrogen-Ion Concentration; Isoindoles; Kinetics; Organoselenium Compounds; Oxidation-Reduction; Oxidoreductases; Thioredoxin-Disulfide Reductase; Thioredoxins

2004
Thiocyanate catalyzes myeloperoxidase-initiated lipid oxidation in LDL.
    Free radical biology & medicine, 2004, Jul-15, Volume: 37, Issue:2

    Topics: Antioxidants; Apoproteins; Ascorbic Acid; Azoles; Catalase; Catalysis; Chlorides; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Female; Free Radicals; Heme; Humans; Hydrogen Peroxide; Hypochlorous Acid; Isoindoles; Lipid Metabolism; Lipid Peroxidation; Lipids; Lipoproteins, LDL; Male; Neutrophils; Nitrites; Organoselenium Compounds; Oxygen; Peroxidase; Phagocytes; Phagocytosis; Risk Factors; Smoking; Thiocyanates; Time Factors; Ultracentrifugation

2004
Transforming growth factor Beta1 induction of tissue inhibitor of metalloproteinases 3 in articular chondrocytes is mediated by reactive oxygen species.
    Free radical biology & medicine, 2004, Jul-15, Volume: 37, Issue:2

    Topics: Acetylcysteine; Animals; Ascorbic Acid; Azoles; Blotting, Northern; Blotting, Western; Cartilage, Articular; Cattle; Cells, Cultured; Chondrocytes; Culture Media, Serum-Free; Cycloheximide; DNA-Binding Proteins; Down-Regulation; Free Radicals; Growth Substances; Humans; Hydrogen Peroxide; Isoindoles; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Oligonucleotides, Antisense; Organoselenium Compounds; Oxidation-Reduction; Phosphorylation; Reactive Oxygen Species; RNA; RNA, Messenger; Signal Transduction; Smad2 Protein; Species Specificity; Time Factors; Tissue Inhibitor of Metalloproteinase-3; Trans-Activators; Transfection; Transforming Growth Factor beta; Transforming Growth Factor beta1

2004
Potent antitumor activity of novel iron chelators derived from di-2-pyridylketone isonicotinoyl hydrazone involves fenton-derived free radical generation.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Nov-01, Volume: 10, Issue:21

    Topics: Antineoplastic Agents; Ascorbic Acid; Azoles; Catalase; Cell Line, Tumor; Chelating Agents; Coloring Agents; DNA; DNA Damage; DNA Topoisomerases, Type I; Dose-Response Relationship, Drug; Free Radicals; Humans; Hydrazones; Hydrogen Peroxide; Iron; Isoindoles; Ligands; Models, Chemical; Organoselenium Compounds; Oxidation-Reduction; Oxygen; Plasmids; Pyridines; Reactive Oxygen Species; Superoxide Dismutase; Tetrazolium Salts; Thiazoles

2004
Diphenyl diselenide reduces temporarily hyperglycemia: possible relationship with oxidative stress.
    Chemico-biological interactions, 2006, Nov-07, Volume: 163, Issue:3

    Topics: Alanine Transaminase; Aminolevulinic Acid; Animals; Antioxidants; Ascorbic Acid; Aspartate Aminotransferases; Azoles; Benzene Derivatives; Blood Glucose; Diabetes Mellitus, Experimental; Fructosamine; Glutathione; Glycated Hemoglobin; Hyperglycemia; Isoindoles; L-Lactate Dehydrogenase; Liver; Male; Organoselenium Compounds; Oxidative Stress; Random Allocation; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Superoxide Dismutase

2006
Ebselen attenuates cadmium-induced testicular damage in mice.
    Journal of applied toxicology : JAT, 2008, Volume: 28, Issue:3

    Topics: Alanine Transaminase; Animals; Antioxidants; Ascorbic Acid; Aspartate Aminotransferases; Azoles; Biomarkers; Cadmium Chloride; Disease Models, Animal; Drug Antagonism; Injections, Intraperitoneal; Isoindoles; Lipid Peroxidation; Male; Mice; Organoselenium Compounds; Porphobilinogen Synthase; Testicular Diseases; Testis; Thiobarbituric Acid Reactive Substances

2008
Dependence of leukemic cell proliferation and survival on H2O2 and L-arginine.
    Free radical biology & medicine, 2009, Apr-15, Volume: 46, Issue:8

    Topics: Acetylcysteine; Antioxidants; Arginase; Arginine; Ascorbic Acid; Azoles; Catalase; Cell Death; Cell Line, Tumor; Cell Proliferation; Humans; Hydrogen Peroxide; Isoindoles; Leukemia; Organoselenium Compounds

2009
Ebselen reduces the toxicity of mechlorethamine in A-431 cells via inhibition of apoptosis.
    Journal of biochemical and molecular toxicology, 2013, Volume: 27, Issue:6

    Topics: Antidotes; Antioxidants; Apoptosis; Ascorbic Acid; Azoles; Caspase 3; Caspase 9; Cell Line; Chemical Warfare Agents; Cytoprotection; Humans; Irritants; Isoindoles; Mechlorethamine; Organoselenium Compounds; Resveratrol; Stilbenes

2013
Characterization of synergistic antibacterial effect of silver nanoparticles and ebselen.
    Artificial cells, nanomedicine, and biotechnology, 2019, Volume: 47, Issue:1

    Topics: Anti-Bacterial Agents; Ascorbic Acid; Azoles; Drug Resistance, Multiple; Drug Synergism; Escherichia coli; HeLa Cells; Humans; Isoindoles; Metal Nanoparticles; Microbial Sensitivity Tests; Organoselenium Compounds; Reactive Oxygen Species; Silver; Staphylococcus aureus

2019