Page last updated: 2024-08-24

ebrotidine and thiazoles

ebrotidine has been researched along with thiazoles in 86 studies

Research

Studies (86)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	80 (93.02)	18.2507
2000's	6 (6.98)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Liu, J; Piotrowski, J; Slomiany, A; Slomiany, BL	1
Morita, M; Piotrowski, J; Slomiany, A; Slomiany, BL; Yamaki, K	1
Kaminski, K; Konturek, SJ; Maczka, J; Oleksy, J; Sito, E; Torres, J	1
Brzozowski, T; Konturek, SJ; Majka, J	1
Gabryelewicz, A; Kamiński, K; Konturek, SJ; Kwiecień, N; Maczka, M; Obtułowicz, W; Oleksy, J; Torres, J	1
Murty, VL; Piotrowski, J; Slomiany, A; Slomiany, BL	2
Morita, M; Piotrowski, J; Slomiany, A; Slomiany, BL	1
Lopez, RA; Slomiany, A; Slomiany, BL	1
Mojtahed, H; Piotrowski, J; Slomiany, A; Slomiany, BL	1
Czajkowski, A; Liu, J; Piotrowski, J; Slomiany, A; Slomiany, BL; Yotsumoto, F	1
Gabryelewicz, A; Majka, J; Murty, VL; Piotrowski, E; Piotrowski, J; Slomiany, A; Slomiany, BL	1
Gómez, F; Ortíz, JA; Romero, A; Sacristán, A; Villamayor, F	2
Czajkowski, A; Gabryelewicz, A; Majka, J; Piotrowski, J; Slomiany, A; Slomiany, BL	1
Butruk, E; Dzieniszewski, J; Gabryelewicz, A; Konturek, SJ; Marlicz, K; Marquez, M; Nowak, A; Ortiz, JA; Torres, J	1
Liau, YH; Murty, VL; Piotrowski, E; Piotrowski, J; Slomiany, A; Slomiany, BL; Zirvi, KA	1
Kaminski, K; Konturek, SJ; Kwiecien, N; Obtulowicz, W; Oleksy, J; Sito, E	1
Albet, C; Anglada, L; Galcerán, MT; Rozman, E	2
Czajkowski, A; Majka, J; Piotrowski, J; Slomiany, A; Slomiany, BL; Yotsumoto, F	1
Czajkowski, A; Kawai, T; Liu, J; Slomiany, A; Slomiany, BL	1
Czajkowski, A; Piotrowski, J; Slomiany, A; Slomiany, BL; Yotsumoto, F	2
Konturek, SJ; Lorens, K; Maj, A; M[aczka, M; Sito, E; Thor, PJ	1
Liau, YH; Lopez, RA; Slomiany, A; Slomiany, BL	1
Albet, C; Galcerán, MT; Rozman, E	2
Piotrowski, J; Slomiany, A; Slomiany, BL	8
Patel, SS; Wilde, MI	1
Piotrowski, E; Piotrowski, J; Slomiany, A; Slomiany, BL	1
Elizalde, JI	1
Piqué, JM	1
Piotrowski, J; Skrodzka, D; Slomiany, A; Slomiany, BL	1
Ortiz, JA	1
Albet, C; Castelló, JM; Fernández, JM; Ortiz, JA; Sacristán, A	1
Agut, J; Conejo, L; Márquez, M; Ortiz, JA; Palop, D; Sacristán, A	1
Agut, J; Ortiz, JA; Sacristán, A; Sánchez, JC	1
Conejo, L; Ortiz, JA; Palop, D; Romero, A; Sacristán, A; Villamayor, F	1
Falcó, J; Ortiz, JA; Palop, D; Romero, A; Sacristán, A; Villamayor, F	1
Conejo, L; Ortiz, JA; Palop, D; Sacristán, A	1
Ortiz, JA; Palacín, C; Sacristán, A; Tarragó, C	1
Albet, C; Ortiz, JA; Pérez, JA; Sacristán, A	1
Albet, C; Ortiz, JA; Rozman, E; Sacristán, A	1
Grau, MT; Ortiz, JA; Romero, A; Sacristán, A; Villamayor, F	4
Ciliutti, P; García, M; Marcos, R; Montero, R; Palacín, C; Romero, A; Vericat, JA; Villamayor, F	1
Grau, MT; Ortiz, JA; Rives, A; Romero, A; Sacristán, A; Villamayor, F	2
Ballesta, A; Gómez, F; Ortiz, JA; Romero, A; Sacristán, A; Villamayor, F	1
Albet, C; Badenas, JM; Farré, M; Herrero, E; Márquez, M; Ortiz, JA; Roset, PN; Ugena, B	1
Albet, C; Carcas, AJ; Esteban, C; Frías, J; Márquez, M; Ortiz, JA; Sánchez-García, P; Torres, J	1
Albet, C; Herrero, E; Márquez, M; Ortiz, JA; Pérez, JA; Rozman, E	1
Camps, F; Fíllat, O; Herrero, E; Honorato, J; Márquez, M; Muñoz-Navas, M; Ortiz, JA; Reina-Ariño, M; Roset, PN; Torres, J; Villamayor, F	1
Aldeguer, M; Chantar, C; Czajkowski, A; Gabryelewicz, A; Luca de Tena, F; Marlicz, K; Márquez, M; Ortiz, JA; Skrodzka, D; Torres, J	1
Döbrönte, Z; Farkas, I; Juhász, L; Márquez, M; Prónai, L; Simon, L; Torres, J; Tulassay, Z	1
Fillat, O; Herrero, E; Krastev, Z; Márquez, M; Matov, V; Metchkov, G; Mitova, R; Ortiz, JA; Tchernev, K; Torres, J	1
Bobrzynski, A; Camps, F; Fillat, O; Gedliczka, O; Herrero, E; Márquez, M; Ortiz, JA; Rembiasz, K; Torres, J	1
Coltau, M; Fillat, O; Herrero, E; Márquez, M; Ortiz, JA; Puscas, C; Puscas, I; Torres, J	1
Coltau, M; Fillat, O; Herrero, E; Márquez, M; Ortiz, JA; Pasca, R; Puscas, C; Puscas, I; Torres, J	1
Fillat, O; Herrero, E; Karcz, D; Kulig, J; Márquez, M; Ortiz, JA; Popiela, T; Tabor, J; Torres, J	1
Brzozowski, T; Konturek, PC; Konturek, SI; Márquez, M; Ortiz, JA; Torres, J	1
Piotrowski, E; Piotrowski, J; Skrodzka, D; Slomiany, A; Slomiany, BL	1
Domschke, WW; Konturek, JW; Piotrowski, J; Slomiany, A; Slomiany, BL	1
Alarcón, T; Domingo, D; López-Brea, M; Martínez, MJ; Sánchez, I; Sanz, JC	1
Castellote, J; Porta, F	1
Hallal, H; Pérez-Gracia, A; Rausell, V; Salinas, E	1
Agúndez, JA; Albet, C; Benítez, J; Carrillo, JA; Herrero, E; Márquez, M; Martínez, C; Ortiz, JA	1
Andrade, RJ; Bellot, V; Bermudez, F; Cárdenas, F; Fernandez, MC; Garcia-Escaño, MD; Gomez-Outes, A; Hervás, A; Lucena, MI; Martin-Vivaldi, R; Nogueras, F; Pelaez, G; Romero, M; Salmerón, J	1
Aguilar, J; Gavilán, F; Guijarro, J; Hernández, A; Larrauri, J; Lissen, E; Macías, J; Pineda, JA; Sayago, M	1
Belda, G; Chuliá, T; Griñó, P; Jover, R; Martínez, R; Palazón, JM; Quílez, C	1
Arroyo, MT; Lanas, A; Sáinz, R	1
Castillo, JR; Hernandez, A; Torelló, J	1
Galceran, MT; Moyano, E; Puignou, L; Sentellas, S	1
Galceran, MT; Hernández-Cassou, S; Puignou, L; Saurina, J; Sentellas, S	1
Kamiya, S; Taguchi, H	1
Galceran, MT; Puignou, L; Sentellas, S	1

Reviews

8 review(s) available for ebrotidine and thiazoles

Article	Year
Ebrotidine. Drugs, 1996, Volume: 51, Issue:6 Topics: Animals; Anti-Ulcer Agents; Benzenesulfonates; Duodenal Ulcer; Histamine H2 Antagonists; Humans; Thiazoles	1996
[Ebrotidine]. Gastroenterologia y hepatologia, 1997, Volume: 20, Issue:2 Topics: Animals; Anti-Ulcer Agents; Benzenesulfonates; Controlled Clinical Trials as Topic; Drug Evaluation, Preclinical; Helicobacter pylori; Histamine H2 Antagonists; Humans; Thiazoles	1997
Gastroprotective properties of ebrotidine. A review. Arzneimittel-Forschung, 1997, Volume: 47, Issue:4A Topics: Animals; Anti-Ulcer Agents; Benzenesulfonates; Gastric Mucins; Gastric Mucosa; Histamine H2 Antagonists; Humans; Mucus; Peptic Ulcer; Phospholipids; Rats; Receptors, Growth Factor; Thiazoles	1997
Anti-Helicobacter pylori activities of ebrotidine. A review of biochemical and animal experimental studies and data. Arzneimittel-Forschung, 1997, Volume: 47, Issue:4A Topics: Animals; Benzenesulfonates; Gastric Mucins; Gastric Mucosa; Helicobacter pylori; Histamine H2 Antagonists; Humans; Lipase; Microbial Sensitivity Tests; Peptide Hydrolases; Polysaccharides, Bacterial; Receptors, Somatostatin; Sulfatases; Thiazoles; Urease	1997
Metabolism of ebrotidine. A review. Arzneimittel-Forschung, 1997, Volume: 47, Issue:4A Topics: Benzenesulfonates; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Histamine H2 Antagonists; Humans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Thiazoles	1997
Studies on the cytoprotective and antisecretory activity of ebrotidine. A review. Arzneimittel-Forschung, 1997, Volume: 47, Issue:4A Topics: Adult; Animals; Benzenesulfonates; Gastric Acid; Gastric Mucosa; Gastrins; Histamine H2 Antagonists; Humans; Male; Peptic Ulcer; Ranitidine; Rats; Rats, Wistar; Thiazoles	1997
[Ebrotidine-induced acute hepatitis]. Gastroenterologia y hepatologia, 1999, Volume: 22, Issue:1 Topics: Acute Disease; Adult; Benzenesulfonates; Chemical and Drug Induced Liver Injury; Chronic Disease; Female; Gastritis; Histamine H2 Antagonists; Humans; Thiazoles	1999
[Prospect of the development of new bactericidal drugs against Helicobacter pylori for eradication therapy]. Nihon rinsho. Japanese journal of clinical medicine, 2002, Volume: 60 Suppl 2 Topics: Animals; Anti-Bacterial Agents; Benzenesulfonates; Carbapenems; Cetylpyridinium; Drug Design; Drug Resistance, Bacterial; Ellagic Acid; Fish Oils; Food Analysis; Glycyrrhizic Acid; Helicobacter Infections; Helicobacter pylori; Nitrofurantoin; Rifamycins; Thiazoles	2002

Trials

18 trial(s) available for ebrotidine and thiazoles

Article	Year
Gastroprotective and antisecretory effects of ebrotidine. Scandinavian journal of gastroenterology, 1992, Volume: 27, Issue:6 Topics: Adult; Benzenesulfonates; Duodenal Ulcer; Ethanol; Gastric Acidity Determination; Gastric Juice; Gastric Mucosa; Gastrins; Gastroscopy; Histamine H2 Antagonists; Humans; Male; Thiazoles	1992
Gastric acid inhibitory profile of ebrotidine, a novel H2-receptor antagonist in humans. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 1992, Volume: 43, Issue:2 Topics: Administration, Oral; Adult; Antacids; Benzenesulfonates; Dose-Response Relationship, Drug; Double-Blind Method; Gastric Acid; Gastric Acidity Determination; Gastric Mucosa; Histamine H2 Antagonists; Humans; Hydrogen-Ion Concentration; Male; Models, Biological; Placebos; Thiazoles	1992
Enhancement in the protective qualities of gastric mucus by ebrotidine during duodenal ulcer healing. General pharmacology, 1995, Volume: 26, Issue:5 Topics: Adult; Anti-Ulcer Agents; Benzenesulfonates; Chemical Phenomena; Chemistry, Physical; Duodenal Ulcer; Gastric Acidity Determination; Gastric Mucosa; Helicobacter pylori; Humans; Molecular Weight; Mucins; Mucus; Thiazoles; Viscosity	1995
Efficacy and safety of ebrotidine compared with ranitidine in patients with duodenal ulcer. European journal of gastroenterology & hepatology, 1995, Volume: 7, Issue:4 Topics: Adult; Anti-Ulcer Agents; Benzenesulfonates; Double-Blind Method; Duodenal Ulcer; Female; Gastrins; Humans; Male; Pancreatic Polypeptide; Ranitidine; Thiazoles	1995
Effects of ebrotidine on aspirin-induced gastric mucosal damage and blood flow in humans. Scandinavian journal of gastroenterology, 1993, Volume: 28, Issue:12 Topics: Adult; Analysis of Variance; Anti-Ulcer Agents; Aspirin; Benzenesulfonates; Blood Flow Velocity; Double-Blind Method; Gastric Mucosa; Histamine H2 Antagonists; Humans; Male; Reference Values; Thiazoles	1993
Double-blind crossover study of ranitidine and ebrotidine in gastro-esophageal reflux disease. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 1993, Volume: 44, Issue:3 Topics: Adult; Aged; Anti-Ulcer Agents; Benzenesulfonates; Double-Blind Method; Endoscopy; Esophagus; Gastroesophageal Reflux; Humans; Hydrogen-Ion Concentration; Male; Middle Aged; Ranitidine; Thiazoles	1993
Investigation of the metabolism of ebrotidine in human urine by liquid chromatography-atmospheric pressure chemical ionization mass spectrometry. Drug metabolism and disposition: the biological fate of chemicals, 1995, Volume: 23, Issue:9 Topics: Benzenesulfonates; Biotransformation; Chromatography, High Pressure Liquid; Histamine H2 Antagonists; Humans; Mass Spectrometry; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Thiazoles	1995
Pharmacokinetic study of ebrotidine administered in multiple doses to healthy volunteers for 4 days. Arzneimittel-Forschung, 1997, Volume: 47, Issue:4A Topics: Adult; Area Under Curve; Benzenesulfonates; Chromatography, High Pressure Liquid; Female; Half-Life; Histamine H2 Antagonists; Humans; Male; Thiazoles	1997
Pharmacokinetics of ebrotidine in healthy volunteers. A summary. Arzneimittel-Forschung, 1997, Volume: 47, Issue:4A Topics: Adult; Area Under Curve; Benzenesulfonates; Chromatography, High Pressure Liquid; Female; Histamine H2 Antagonists; Humans; Male; Thiazoles	1997
Continuous intragastric pH monitoring in the evaluation of ebrotidine, cimetidine and placebo on gastric acidity in healthy volunteers. Arzneimittel-Forschung, 1997, Volume: 47, Issue:4A Topics: Adult; Benzenesulfonates; Double-Blind Method; Female; Gastric Acid; Gastric Acidity Determination; Histamine H2 Antagonists; Humans; Hydrogen-Ion Concentration; Male; Monitoring, Physiologic; Thiazoles	1997
Comparison of the efficacy and safety of ebrotidine in the treatment of duodenal ulcer. A multicentre, double-blind, placebo-controlled phase II study. Arzneimittel-Forschung, 1997, Volume: 47, Issue:4A Topics: Abdominal Pain; Adult; Benzenesulfonates; Double-Blind Method; Duodenal Ulcer; Female; Histamine H2 Antagonists; Humans; Male; Middle Aged; Thiazoles	1997
Ebrotidine versus ranitidine in the healing and prevention of relapse of duodenal ulcer. A multicentre, double-blind, parallel, randomized, controlled study. Arzneimittel-Forschung, 1997, Volume: 47, Issue:4A Topics: Adult; Benzenesulfonates; Double-Blind Method; Female; Follow-Up Studies; Histamine H2 Antagonists; Humans; Male; Middle Aged; Ranitidine; Recurrence; Smoking; Thiazoles	1997
Ebrotidine versus ranitidine in the treatment of acute duodenal ulcer. A multicentre, randomized, double-blind, controlled clinical trial. Arzneimittel-Forschung, 1997, Volume: 47, Issue:4A Topics: Abdominal Pain; Adult; Benzenesulfonates; Double-Blind Method; Duodenal Ulcer; Female; Histamine H2 Antagonists; Humans; Male; Middle Aged; Ranitidine; Smoking; Thiazoles	1997
Efficacy of ebrotidine and ranitidine in the treatment of benign gastric ulcer. Arzneimittel-Forschung, 1997, Volume: 47, Issue:4A Topics: Adult; Aged; Benzenesulfonates; Double-Blind Method; Female; Histamine H2 Antagonists; Humans; Male; Middle Aged; Ranitidine; Stomach Ulcer; Thiazoles	1997
Studies on the protective effect of ebrotidine on experimental ulcers induced by non-steroidal anti-inflammatory drugs in healthy volunteers. Arzneimittel-Forschung, 1997, Volume: 47, Issue:4A Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Benzenesulfonates; Carbonic Anhydrases; Female; Gastric Mucosa; Histamine H2 Antagonists; Humans; Indomethacin; Male; Middle Aged; Stomach Ulcer; Thiazoles	1997
Comparative study of the safety and efficacy of ebrotidine versus ranitidine and placebo in the prevention of piroxicam-induced gastroduodenal lesions. Arzneimittel-Forschung, 1997, Volume: 47, Issue:4A Topics: Adult; Benzenesulfonates; Duodenal Ulcer; Female; Histamine H2 Antagonists; Humans; Male; Middle Aged; Piroxicam; Ranitidine; Stomach Ulcer; Thiazoles	1997
Efficacy of ebrotidine and ranitidine combined with amoxicillin and metronidazole in the eradication of Helicobacter pylori in patients with duodenal ulcer. Arzneimittel-Forschung, 1997, Volume: 47, Issue:4A Topics: Adult; Amoxicillin; Benzenesulfonates; Double-Blind Method; Duodenal Ulcer; Female; Gastritis; Helicobacter Infections; Helicobacter pylori; Histamine H2 Antagonists; Humans; Male; Metronidazole; Middle Aged; Ranitidine; Thiazoles	1997
Comparative in vitro and in vivo inhibition of cytochrome P450 CYP1A2, CYP2D6, and CYP3A by H2-receptor antagonists. Clinical pharmacology and therapeutics, 1999, Volume: 65, Issue:4 Topics: Adult; Anti-Anxiety Agents; Antitussive Agents; Aryl Hydrocarbon Hydroxylases; Benzenesulfonates; Caffeine; Central Nervous System Stimulants; Cimetidine; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Dextromethorphan; Double-Blind Method; Histamine H2 Antagonists; Humans; In Vitro Techniques; Male; Methylation; Microsomes, Liver; Midazolam; Oxidoreductases, N-Demethylating; Psychomotor Performance; Ranitidine; Thiazoles	1999

Other Studies

60 other study(ies) available for ebrotidine and thiazoles

Article	Year
Inhibition of EGF-induced gastric mucosal calcium channel phosphorylation by ebrotidine. Biochemistry international, 1992, Volume: 28, Issue:4 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Anti-Ulcer Agents; Benzenesulfonates; Calcium Channels; Calcium Radioisotopes; Epidermal Growth Factor; Gastric Mucosa; Isradipine; Phosphorylation; Phosphotyrosine; Rats; Thiazoles; Tyrosine	1992
Ebrotidine--a new H2-receptor antagonist with mucosal strengthening activity. Biochemistry international, 1992, Volume: 26, Issue:4 Topics: Animals; Benzenesulfonates; Dose-Response Relationship, Drug; Ethanol; Gastric Mucosa; Gels; Glycoproteins; Histamine H2 Antagonists; Mucus; Phospholipids; Rats; Thiazoles; Viscosity	1992
Gastroprotective and ulcer-healing activities of a new H2-receptor antagonist: ebrotidine. Digestion, 1992, Volume: 51, Issue:1 Topics: Acetates; Acetic Acid; Animals; Benzenesulfonates; Epidermal Growth Factor; Ethanol; Gastric Acid; Gastric Mucosa; Gastrins; Histamine H2 Antagonists; Male; Ranitidine; Rats; Rats, Inbred Strains; Regional Blood Flow; Stomach Ulcer; Thiazoles	1992
Mechanism of ebrotidine protection against gastric mucosal injury induced by ethanol. General pharmacology, 1992, Volume: 23, Issue:4 Topics: Animals; Benzenesulfonates; Chemical Phenomena; Chemistry, Physical; Ethanol; Gastric Mucosa; Histamine H2 Antagonists; Hydrogen; Male; Mucus; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Thiazoles; Viscosity	1992
Inhibition of gastric mucosal laminin receptor by Helicobacter pylori lipopolysaccharide: effect of ebrotidine. Biochemistry international, 1992, Volume: 27, Issue:1 Topics: Animals; Benzenesulfonates; Gastric Mucosa; Helicobacter pylori; In Vitro Techniques; Laminin; Lipopolysaccharides; Rats; Receptors, Antigen; Receptors, Immunologic; Receptors, Laminin; Thiazoles	1992
Synthesis and secretion of gastric sulfomucin in the presence of ebrotidine, a new antiulcer agent. Biochemistry international, 1992, Volume: 28, Issue:4 Topics: Animals; Anti-Ulcer Agents; Benzenesulfonates; Dose-Response Relationship, Drug; Gastric Mucosa; Glucosamine; Glycosylation; Kinetics; Mucins; Proline; Rats; Sulfates; Thiazoles	1992
Ebrotidine effect on the proteolytic and lipolytic activities of Helicobacter pylori. General pharmacology, 1992, Volume: 23, Issue:2 Topics: Anti-Ulcer Agents; Benzenesulfonates; Endopeptidases; Gastric Mucosa; Helicobacter pylori; Humans; In Vitro Techniques; Lipase; Lipolysis; Male; Phospholipases; Protease Inhibitors; Thiazoles	1992
Regulation of gastric mucosal calcium channel activity by an antiulcer agent, ebrotidine. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 1994, Volume: 45, Issue:1 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Anti-Ulcer Agents; Benzenesulfonates; Calcium; Calcium Channels; Calcium Radioisotopes; Epidermal Growth Factor; Gastric Mucosa; Histamine H2 Antagonists; Isradipine; Liposomes; Male; Membranes; Phosphorylation; Rats; Rats, Sprague-Dawley; Thiazoles	1994
Helicobacter pylori aggregating activity of gastric mucin with ulcer healing by ebrotidine. Biochemistry and molecular biology international, 1994, Volume: 34, Issue:5 Topics: Anti-Ulcer Agents; Benzenesulfonates; Duodenal Ulcer; Gastric Mucins; Helicobacter pylori; Humans; Thiazoles	1994
Effect of ebrotidine on the density of antral G-cells in the gastric mucosa in the rat. Cell proliferation, 1995, Volume: 28, Issue:7 Topics: Animals; Benzenesulfonates; Cell Count; Cell Division; Cimetidine; Gastric Mucosa; Histamine H2 Antagonists; Immunohistochemistry; Male; Pyloric Antrum; Rats; Rats, Sprague-Dawley; Thiazoles	1995
Enhancement of gastric mucus phospholipid secretion by an antiulcer agent, ebrotidine. General pharmacology, 1994, Volume: 25, Issue:5 Topics: Animals; Anti-Ulcer Agents; Benzenesulfonates; Choline; Cyclic AMP; Gastric Mucosa; Male; Mucus; Phospholipids; Ranitidine; Rats; Rats, Sprague-Dawley; Thiazoles	1994
Metabolites of ebrotidine, a new H2-receptor antagonist, in human urine. Journal of pharmaceutical sciences, 1994, Volume: 83, Issue:2 Topics: Benzenesulfonates; Biotransformation; Bromobenzenes; Chromatography, High Pressure Liquid; Histamine H2 Antagonists; Humans; Magnetic Resonance Spectroscopy; Male; Spectrophotometry, Infrared; Sulfonamides; Thiazoles	1994
Gastric mucosal laminin receptor expression with ulcer healing by ebrotidine. General pharmacology, 1994, Volume: 25, Issue:3 Topics: Amino Acid Sequence; Animals; Anti-Ulcer Agents; Benzenesulfonates; Cell Division; Cell Membrane; Gastric Mucosa; Male; Molecular Sequence Data; Rats; Rats, Sprague-Dawley; Receptors, Laminin; Stomach Ulcer; Thiazoles; Wound Healing	1994
Effect of ebrotidine on gastric mucosal calcium channel activity. The American journal of gastroenterology, 1993, Volume: 88, Issue:6 Topics: Animals; Benzenesulfonates; Calcium; Calcium Channels; Chromatography, Affinity; Epidermal Growth Factor; Gastric Mucosa; Histamine H2 Antagonists; Male; Rats; Rats, Sprague-Dawley; Thiazoles	1993
Effect of ebrotidine on gastric mucosal EGF and PDGF receptor expression. Biochemistry and molecular biology international, 1993, Volume: 30, Issue:6 Topics: Animals; Benzenesulfonates; Cell Membrane; Epidermal Growth Factor; ErbB Receptors; Gastric Mucosa; Histamine H2 Antagonists; Phosphorylation; Platelet-Derived Growth Factor; Ranitidine; Rats; Receptors, Platelet-Derived Growth Factor; Thiazoles; Tyrosine	1993
Gastric mucosal EGF and PDGF receptor expression with ulcer healing by ebrotidine. The American journal of gastroenterology, 1994, Volume: 89, Issue:6 Topics: Animals; Anti-Ulcer Agents; Benzenesulfonates; ErbB Receptors; Gastric Mucosa; Male; Rats; Rats, Sprague-Dawley; Receptors, Platelet-Derived Growth Factor; Stomach Ulcer; Thiazoles	1994
Effect of ebrotidine on the synthesis and secretion of gastric sulfomucin. General pharmacology, 1993, Volume: 24, Issue:3 Topics: Animals; Anti-Ulcer Agents; Benzenesulfonates; Gastric Mucosa; Glucosamine; Glycoproteins; In Vitro Techniques; Mucins; Proline; Rats; Sulfates; Sulfur Radioisotopes; Thiazoles	1993
Ebrotidine and its metabolites studied by mass spectrometry with electrospray ionization. Comparison of tandem and in-source fragmentation... Rapid communications in mass spectrometry : RCM, 1995, Volume: 9, Issue:15 Topics: Benzenesulfonates; Gas Chromatography-Mass Spectrometry; Histamine H2 Antagonists; Humans; Thiazoles	1995
Inhibition of Helicobacter pylori urease activity by ebrotidine. Biochemistry and molecular biology international, 1995, Volume: 37, Issue:2 Topics: Anti-Ulcer Agents; Benzenesulfonates; Dose-Response Relationship, Drug; Helicobacter pylori; Ranitidine; Thiazoles; Urease	1995
Inhibition of gastric mucosal mucin receptor by H. pylori lipopolysaccharide: effect of ebrotidine. General pharmacology, 1995, Volume: 26, Issue:7 Topics: Animals; Anti-Ulcer Agents; Benzenesulfonates; Gastric Mucins; Helicobacter pylori; Lipopolysaccharides; Male; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Thiazoles	1995
Susceptibility of Helicobacter pylori to antimicrobial agents: effect of ebrotidine and ranitidine. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 1995, Volume: 46, Issue:4 Topics: Anti-Bacterial Agents; Benzenesulfonates; Drug Interactions; Helicobacter pylori; Histamine H2 Antagonists; Microbial Sensitivity Tests; Ranitidine; Thiazoles	1995
Susceptibility of growth factors to degradation by Helicobacter pylori protease: effect of ebrotidine and sucralfate. Biochemistry and molecular biology international, 1996, Volume: 40, Issue:1 Topics: Benzenesulfonates; Endopeptidases; Helicobacter pylori; Histamine H2 Antagonists; Platelet-Derived Growth Factor; Sucralfate; Thiazoles; Transforming Growth Factor beta	1996
Determination of ebrotidine and its metabolites in human urine by reversed-phase ion-pair high-performance liquid chromatography. Journal of chromatography. B, Biomedical sciences and applications, 1997, Jan-10, Volume: 688, Issue:1 Topics: Administration, Oral; Anti-Ulcer Agents; Benzenesulfonates; Chromatography, High Pressure Liquid; Circadian Rhythm; Histamine H2 Antagonists; Humans; Hydrogen-Ion Concentration; Linear Models; Reproducibility of Results; Sensitivity and Specificity; Thiazoles; Time Factors	1997
[Ebrotidine: an new alternative in peptic acid diseases]. Medicina clinica, 1997, Mar-01, Volume: 108, Issue:8 Topics: Anti-Ulcer Agents; Benzenesulfonates; Histamine H2 Antagonists; Humans; Peptic Ulcer; Thiazoles	1997
Reversal of gastric somatostatin receptor inhibition by Helicobacter pylori lipopolysaccharide with ebrotidine and sulglycotide. General pharmacology, 1997, Volume: 28, Issue:5 Topics: Animals; Anti-Ulcer Agents; Benzenesulfonates; Cell Membrane; Gastric Mucosa; Helicobacter pylori; Lipopolysaccharides; Rats; Receptors, Somatostatin; Sialoglycoproteins; Somatostatin; Thiazoles	1997
Ebrotidine. A new generation H2-receptor antagonist and gastroprotective agent. Introduction. Arzneimittel-Forschung, 1997, Volume: 47, Issue:4A Topics: Animals; Benzenesulfonates; Histamine H2 Antagonists; Humans; Thiazoles	1997
Physicochemical properties, analytical determinations and stability of ebrotidine. Arzneimittel-Forschung, 1997, Volume: 47, Issue:4A Topics: Benzenesulfonates; Chromatography, High Pressure Liquid; Histamine H2 Antagonists; Magnetic Resonance Spectroscopy; Mass Spectrometry; Potentiometry; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Thiazoles; X-Ray Diffraction	1997
Histamine H2-receptor antagonist action of ebrotidine. Effects on gastric acid secretion, gastrin levels and NSAID-induced gastrotoxicity in the rat. Arzneimittel-Forschung, 1997, Volume: 47, Issue:4A Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzenesulfonates; Diclofenac; Dose-Response Relationship, Drug; Female; Gastric Acid; Gastrins; Guinea Pigs; Heart Atria; Heart Rate; Histamine; Histamine H2 Antagonists; In Vitro Techniques; Indomethacin; Ketoprofen; Male; Naproxen; Pentagastrin; Ranitidine; Rats; Rats, Sprague-Dawley; Rats, Wistar; Thiazoles	1997
Action of ebrotidine, ranitidine and cimetidine on the specific binding to histamine H1- and H2-receptors. Arzneimittel-Forschung, 1997, Volume: 47, Issue:4A Topics: Animals; Benzenesulfonates; Cell Membrane; Cerebellum; Cerebral Cortex; Cimetidine; Depression, Chemical; Guinea Pigs; Histamine H2 Antagonists; In Vitro Techniques; Isotope Labeling; Male; Protein Binding; Pyrilamine; Ranitidine; Receptors, Histamine H1; Receptors, Histamine H2; Thiazoles; Tritium	1997
Effect of ebrotidine on ethanol-induced gastric mucosal damage in the rat. Comparative study with other H2-receptor antagonists. Arzneimittel-Forschung, 1997, Volume: 47, Issue:4A Topics: Animals; Benzenesulfonates; Cimetidine; Dose-Response Relationship, Drug; Ethanol; Famotidine; Female; Gastric Mucosa; Histamine H2 Antagonists; Indomethacin; Peptic Ulcer; Ranitidine; Rats; Rats, Sprague-Dawley; Thiazoles	1997
Study on the increment of the amount of gastric mucus in rats after repeated-dose administration of ebrotidine. Arzneimittel-Forschung, 1997, Volume: 47, Issue:4A Topics: Animals; Benzenesulfonates; Female; Gastric Mucosa; Histamine H2 Antagonists; Mucus; Rats; Rats, Sprague-Dawley; Specific Pathogen-Free Organisms; Thiazoles	1997
Involvement of endogenous nitric oxide and sulfhydryl compounds in ebrotidine-induced gastroprotection. Arzneimittel-Forschung, 1997, Volume: 47, Issue:4A Topics: Animals; Arginine; Benzenesulfonates; Ethanol; Ethylmaleimide; Gastric Mucosa; Histamine H2 Antagonists; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peptic Ulcer; Rats; Rats, Sprague-Dawley; Specific Pathogen-Free Organisms; Sulfhydryl Compounds; Thiazoles	1997
In vitro anti-Helicobacter pylori activity of ebrotidine. Arzneimittel-Forschung, 1997, Volume: 47, Issue:4A Topics: Amoxicillin; Benzenesulfonates; Clarithromycin; Drug Synergism; Erythromycin; Helicobacter pylori; Histamine H2 Antagonists; Metronidazole; Microbial Sensitivity Tests; Ranitidine; Tetracycline; Thiazoles	1997
Pharmacokinetics of ebrotidine in rats and dogs. Arzneimittel-Forschung, 1997, Volume: 47, Issue:4A Topics: Administration, Oral; Animals; Area Under Curve; Benzenesulfonates; Dogs; Female; Half-Life; Histamine H2 Antagonists; Injections, Intravenous; Intestinal Absorption; Male; Models, Biological; Rats; Rats, Sprague-Dawley; Thiazoles	1997
Acute toxicity studies of ebrotidine. Arzneimittel-Forschung, 1997, Volume: 47, Issue:4A Topics: Administration, Oral; Animals; Benzenesulfonates; Female; Histamine H2 Antagonists; Injections, Intraperitoneal; Injections, Intravenous; Lethal Dose 50; Male; Mice; Rats; Rats, Sprague-Dawley; Specific Pathogen-Free Organisms; Thiazoles	1997
Subacute toxicity of ebrotidine in rats and dogs. Arzneimittel-Forschung, 1997, Volume: 47, Issue:4A Topics: Animals; Benzenesulfonates; Blood Chemical Analysis; Body Weight; Dogs; Eating; Female; Histamine H2 Antagonists; Male; Organ Size; Rats; Rats, Sprague-Dawley; Thiazoles; Urinalysis	1997
Chronic toxicity of ebrotidine in rats and dogs. Arzneimittel-Forschung, 1997, Volume: 47, Issue:4A Topics: Animals; Benzenesulfonates; Blood Chemical Analysis; Body Weight; Dogs; Eating; Female; Histamine H2 Antagonists; Male; Organ Size; Rats; Rats, Sprague-Dawley; Thiazoles	1997
Toxicity of ebrotidine on reproduction. Toxicity on fertility and general reproductive performance, embryo-fetal toxicity and peri- and postnatal toxicity. Arzneimittel-Forschung, 1997, Volume: 47, Issue:4A Topics: Abnormalities, Drug-Induced; Animals; Benzenesulfonates; Embryonic and Fetal Development; Female; Fertility; Fetal Viability; Histamine H2 Antagonists; Male; Pregnancy; Rabbits; Rats; Rats, Sprague-Dawley; Reproduction; Thiazoles	1997
Genotoxicity studies on ebrotidine. Arzneimittel-Forschung, 1997, Volume: 47, Issue:4A Topics: Animals; Benzenesulfonates; Chromosome Aberrations; Drosophila melanogaster; Erythrocytes; Genes; Genes, Bacterial; Histamine H2 Antagonists; Humans; Lymphocytes; Mice; Micronucleus Tests; Mutagenicity Tests; Salmonella typhimurium; Sister Chromatid Exchange; Thiazoles	1997
Carcinogenicity studies on ebrotidine. Arzneimittel-Forschung, 1997, Volume: 47, Issue:4A Topics: Animals; Benzenesulfonates; Body Weight; Carcinogenicity Tests; Female; Histamine H2 Antagonists; Male; Mice; Neoplasms; Rats; Rats, Sprague-Dawley; Specific Pathogen-Free Organisms; Survival Rate; Thiazoles	1997
Study of the population of antral G-cells and enterochromaffin-like cells in the rat and mouse gastric mucosa after long-term treatment with ebrotidine. Arzneimittel-Forschung, 1997, Volume: 47, Issue:4A Topics: Animals; Benzenesulfonates; Cell Count; Enterochromaffin Cells; Female; Gastric Mucosa; Histamine H2 Antagonists; Male; Mice; Pyloric Antrum; Rats; Rats, Sprague-Dawley; Specific Pathogen-Free Organisms; Thiazoles	1997
Comparative study of plasma gastrin levels in rats after two months of ebrotidine administration. Arzneimittel-Forschung, 1997, Volume: 47, Issue:4A Topics: Animals; Benzenesulfonates; Cimetidine; Gastrins; Histamine H2 Antagonists; Male; Omeprazole; Ranitidine; Rats; Rats, Sprague-Dawley; Specific Pathogen-Free Organisms; Thiazoles	1997
Tolerability and pharmacokinetics of ebrotidine in healthy subjects given single and repeated oral doses. Arzneimittel-Forschung, 1997, Volume: 47, Issue:4A Topics: Administration, Oral; Adult; Benzenesulfonates; Half-Life; Histamine H2 Antagonists; Humans; Male; Thiazoles	1997
Gastric mucosal apoptosis induced by ethanol: effect of antiulcer agents. Biochemistry and molecular biology international, 1997, Volume: 42, Issue:2 Topics: Animals; Anti-Ulcer Agents; Apoptosis; Benzenesulfonates; Ethanol; Gastric Mucosa; Histamine H2 Antagonists; Omeprazole; Proton Pump Inhibitors; Rats; Rats, Sprague-Dawley; Sucralfate; Thiazoles; Tumor Necrosis Factor-alpha	1997
Induction of tumor necrosis factor-alpha and apoptosis in gastric mucosal injury by indomethacin: effect of omeprazole and ebrotidine. Scandinavian journal of gastroenterology, 1997, Volume: 32, Issue:7 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Apoptosis; Benzenesulfonates; Gastric Mucosa; Indomethacin; Omeprazole; Premedication; Rats; Rats, Sprague-Dawley; Thiazoles; Time Factors; Tumor Necrosis Factor-alpha	1997
Cell cycle progression during gastric ulcer healing by ebrotidine and sucralfate. General pharmacology, 1997, Volume: 29, Issue:3 Topics: Animals; Anti-Ulcer Agents; Benzenesulfonates; Cell Cycle; Cyclin-Dependent Kinases; Gastric Mucosa; In Vitro Techniques; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Sucralfate; Thiazoles	1997
Enhancement in the protective qualities of gastric mucus with combination therapy of ebrotidine and amoxicillin for H. pylori eradication. General pharmacology, 1998, Volume: 31, Issue:2 Topics: Adult; Amoxicillin; Anti-Ulcer Agents; Benzenesulfonates; Chemical Phenomena; Chemistry, Physical; Drug Evaluation, Preclinical; Drug Therapy, Combination; Gastric Mucosa; Gastritis; Helicobacter pylori; Humans; Mucus; Penicillins; Permeability; Solubility; Thiazoles; Viscosity	1998
In vitro activity of ebrotidine, ranitidine, omeprazole, lansoprazole, and bismuth citrate against clinical isolates of Helicobacter pylori. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1998, Volume: 17, Issue:4 Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Bacterial Agents; Anti-Ulcer Agents; Benzenesulfonates; Helicobacter pylori; Lansoprazole; Microbial Sensitivity Tests; Omeprazole; Organometallic Compounds; Ranitidine; Thiazoles	1998
[Toxic hepatitis caused by ebrotidine]. Medicina clinica, 1998, Nov-21, Volume: 111, Issue:17 Topics: Benzenesulfonates; Chemical and Drug Induced Liver Injury; Histamine H2 Antagonists; Humans; Male; Middle Aged; Thiazoles	1998
Twenty-four-month oral carcinogenicity study of ebrotidine in rats. Teratogenesis, carcinogenesis, and mutagenesis, 1998, Volume: 18, Issue:6 Topics: Animals; Benzenesulfonates; Body Weight; Carcinogens; Dose-Response Relationship, Drug; Feeding Behavior; Female; Gastric Mucosa; Histamine H2 Antagonists; Male; Neoplasms, Experimental; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Risk; Sex Factors; Survival Rate; Thiazoles; Time Factors; Tissue Distribution	1998
Endothelin-1, interleukin-4 and nitric oxide synthase modulators of gastric mucosal injury by indomethacin: effect of antiulcer agents. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 1999, Volume: 50, Issue:2 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Apoptosis; Benzenesulfonates; Endothelin-1; Gastric Mucosa; Indomethacin; Interleukin-4; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Ranitidine; Rats; Rats, Sprague-Dawley; Sialoglycoproteins; Stomach Ulcer; Thiazoles	1999
Acute liver injury associated with the use of ebrotidine, a new H2-receptor antagonist. Journal of hepatology, 1999, Volume: 31, Issue:4 Topics: Acute Disease; Adult; Aged; Alanine Transaminase; Aspartate Aminotransferases; Benzenesulfonates; Bilirubin; Chemical and Drug Induced Liver Injury; Female; Histamine H2 Antagonists; Humans; Liver; Liver Failure; Male; Middle Aged; Necrosis; Thiazoles	1999
Rapid progression to liver cirrhosis of toxic hepatitis due to ebrotidine. Journal of hepatology, 1999, Volume: 31, Issue:4 Topics: Adult; Anti-Ulcer Agents; Benzenesulfonates; Chemical and Drug Induced Liver Injury; Disease Progression; Female; Histamine H2 Antagonists; Humans; Liver Cirrhosis; Male; Middle Aged; Thiazoles; Time Factors	1999
Effect of ebrotidine on gastric mucosal inflammatory responses to Helicobacter pylori lipopolysaccharide. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 1999, Volume: 50, Issue:3 Topics: Acute Disease; Animals; Anti-Ulcer Agents; Benzenesulfonates; Disease Models, Animal; Gastric Mucosa; Gastritis; Helicobacter Infections; Helicobacter pylori; Lipopolysaccharides; Rats; Rats, Sprague-Dawley; Thiazoles	1999
[Hepatoxicity due to ebrotidine: report of two cases]. Gastroenterologia y hepatologia, 1999, Volume: 22, Issue:8 Topics: Adult; Anti-Ulcer Agents; Benzenesulfonates; Chemical and Drug Induced Liver Injury; Female; Histamine H2 Antagonists; Humans; Male; Middle Aged; Thiazoles	1999
Prevention and healing of experimental indomethacin-induced gastric lesions: effects of ebrotidine, omeprazole and ranitidine. European journal of gastroenterology & hepatology, 2000, Volume: 12, Issue:3 Topics: Animals; Anti-Ulcer Agents; Benzenesulfonates; Disease Models, Animal; Gastric Juice; Histamine H2 Antagonists; Indomethacin; Male; Omeprazole; Ranitidine; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Thiazoles	2000
Liver injury caused by ebrotidine: a new example of the utility of the postmarketing surveillance. European journal of clinical pharmacology, 2000, Volume: 56, Issue:2 Topics: Adult; Adverse Drug Reaction Reporting Systems; Aged; Anti-Ulcer Agents; Benzenesulfonates; Chemical and Drug Induced Liver Injury; Female; Histamine H2 Antagonists; Humans; Male; Middle Aged; Thiazoles	2000
Determination of ebrotidine and its metabolites by capillary electrophoresis with UV and mass spectrometry detection. Journal of chromatography. A, 2000, Aug-04, Volume: 888, Issue:1-2 Topics: Benzenesulfonates; Buffers; Cations; Electrolytes; Electrophoresis, Capillary; Histamine H2 Antagonists; Mass Spectrometry; Reproducibility of Results; Sensitivity and Specificity; Solvents; Spectrophotometry, Ultraviolet; Thiazoles	2000
Determination of ebrotidine metabolites in overlapping peaks from capillary zone electrophoresis using chemometric methods. Electrophoresis, 2001, Volume: 22, Issue:1 Topics: Benzenesulfonates; Bromobenzenes; Electrophoresis, Capillary; Histamine H2 Antagonists; Molecular Structure; Sulfonamides; Thiazoles	2001
Determination of ebrotidine and its metabolites by micellar electrokinetic capillary chromatography. Journal of chromatography. A, 2002, Nov-08, Volume: 976, Issue:1-2 Topics: Benzenesulfonates; Buffers; Chromatography, Micellar Electrokinetic Capillary; Histamine H2 Antagonists; Humans; Hydrogen-Ion Concentration; Reference Standards; Sensitivity and Specificity; Sodium Dodecyl Sulfate; Thiazoles	2002