Page last updated: 2024-08-24

ebrotidine and ranitidine

ebrotidine has been researched along with ranitidine in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's21 (87.50)18.2507
2000's1 (4.17)29.6817
2010's2 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brzozowski, T; Konturek, SJ; Majka, J1
Butruk, E; Dzieniszewski, J; Gabryelewicz, A; Konturek, SJ; Marlicz, K; Marquez, M; Nowak, A; Ortiz, JA; Torres, J1
Liau, YH; Murty, VL; Piotrowski, E; Piotrowski, J; Slomiany, A; Slomiany, BL; Zirvi, KA1
Czajkowski, A; Piotrowski, J; Slomiany, A; Slomiany, BL; Yotsumoto, F1
Konturek, SJ; Lorens, K; Maj, A; M[aczka, M; Sito, E; Thor, PJ1
Piotrowski, J; Slomiany, A; Slomiany, BL2
Piotrowski, E; Piotrowski, J; Slomiany, A; Slomiany, BL1
Agut, J; Conejo, L; Márquez, M; Ortiz, JA; Palop, D; Sacristán, A1
Agut, J; Ortiz, JA; Sacristán, A; Sánchez, JC1
Conejo, L; Ortiz, JA; Palop, D; Romero, A; Sacristán, A; Villamayor, F1
Ortiz, JA; Palacín, C; Sacristán, A; Tarragó, C1
Ballesta, A; Gómez, F; Ortiz, JA; Romero, A; Sacristán, A; Villamayor, F1
Döbrönte, Z; Farkas, I; Juhász, L; Márquez, M; Prónai, L; Simon, L; Torres, J; Tulassay, Z1
Fillat, O; Herrero, E; Krastev, Z; Márquez, M; Matov, V; Metchkov, G; Mitova, R; Ortiz, JA; Tchernev, K; Torres, J1
Bobrzynski, A; Camps, F; Fillat, O; Gedliczka, O; Herrero, E; Márquez, M; Ortiz, JA; Rembiasz, K; Torres, J1
Coltau, M; Fillat, O; Herrero, E; Márquez, M; Ortiz, JA; Pasca, R; Puscas, C; Puscas, I; Torres, J1
Fillat, O; Herrero, E; Karcz, D; Kulig, J; Márquez, M; Ortiz, JA; Popiela, T; Tabor, J; Torres, J1
Brzozowski, T; Konturek, PC; Konturek, SI; Márquez, M; Ortiz, JA; Torres, J1
Alarcón, T; Domingo, D; López-Brea, M; Martínez, MJ; Sánchez, I; Sanz, JC1
Agúndez, JA; Albet, C; Benítez, J; Carrillo, JA; Herrero, E; Márquez, M; Martínez, C; Ortiz, JA1
Arroyo, MT; Lanas, A; Sáinz, R1

Reviews

2 review(s) available for ebrotidine and ranitidine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Studies on the cytoprotective and antisecretory activity of ebrotidine. A review.
    Arzneimittel-Forschung, 1997, Volume: 47, Issue:4A

    Topics: Adult; Animals; Benzenesulfonates; Gastric Acid; Gastric Mucosa; Gastrins; Histamine H2 Antagonists; Humans; Male; Peptic Ulcer; Ranitidine; Rats; Rats, Wistar; Thiazoles

1997

Trials

8 trial(s) available for ebrotidine and ranitidine

ArticleYear
Efficacy and safety of ebrotidine compared with ranitidine in patients with duodenal ulcer.
    European journal of gastroenterology & hepatology, 1995, Volume: 7, Issue:4

    Topics: Adult; Anti-Ulcer Agents; Benzenesulfonates; Double-Blind Method; Duodenal Ulcer; Female; Gastrins; Humans; Male; Pancreatic Polypeptide; Ranitidine; Thiazoles

1995
Double-blind crossover study of ranitidine and ebrotidine in gastro-esophageal reflux disease.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 1993, Volume: 44, Issue:3

    Topics: Adult; Aged; Anti-Ulcer Agents; Benzenesulfonates; Double-Blind Method; Endoscopy; Esophagus; Gastroesophageal Reflux; Humans; Hydrogen-Ion Concentration; Male; Middle Aged; Ranitidine; Thiazoles

1993
Ebrotidine versus ranitidine in the healing and prevention of relapse of duodenal ulcer. A multicentre, double-blind, parallel, randomized, controlled study.
    Arzneimittel-Forschung, 1997, Volume: 47, Issue:4A

    Topics: Adult; Benzenesulfonates; Double-Blind Method; Female; Follow-Up Studies; Histamine H2 Antagonists; Humans; Male; Middle Aged; Ranitidine; Recurrence; Smoking; Thiazoles

1997
Ebrotidine versus ranitidine in the treatment of acute duodenal ulcer. A multicentre, randomized, double-blind, controlled clinical trial.
    Arzneimittel-Forschung, 1997, Volume: 47, Issue:4A

    Topics: Abdominal Pain; Adult; Benzenesulfonates; Double-Blind Method; Duodenal Ulcer; Female; Histamine H2 Antagonists; Humans; Male; Middle Aged; Ranitidine; Smoking; Thiazoles

1997
Efficacy of ebrotidine and ranitidine in the treatment of benign gastric ulcer.
    Arzneimittel-Forschung, 1997, Volume: 47, Issue:4A

    Topics: Adult; Aged; Benzenesulfonates; Double-Blind Method; Female; Histamine H2 Antagonists; Humans; Male; Middle Aged; Ranitidine; Stomach Ulcer; Thiazoles

1997
Comparative study of the safety and efficacy of ebrotidine versus ranitidine and placebo in the prevention of piroxicam-induced gastroduodenal lesions.
    Arzneimittel-Forschung, 1997, Volume: 47, Issue:4A

    Topics: Adult; Benzenesulfonates; Duodenal Ulcer; Female; Histamine H2 Antagonists; Humans; Male; Middle Aged; Piroxicam; Ranitidine; Stomach Ulcer; Thiazoles

1997
Efficacy of ebrotidine and ranitidine combined with amoxicillin and metronidazole in the eradication of Helicobacter pylori in patients with duodenal ulcer.
    Arzneimittel-Forschung, 1997, Volume: 47, Issue:4A

    Topics: Adult; Amoxicillin; Benzenesulfonates; Double-Blind Method; Duodenal Ulcer; Female; Gastritis; Helicobacter Infections; Helicobacter pylori; Histamine H2 Antagonists; Humans; Male; Metronidazole; Middle Aged; Ranitidine; Thiazoles

1997
Comparative in vitro and in vivo inhibition of cytochrome P450 CYP1A2, CYP2D6, and CYP3A by H2-receptor antagonists.
    Clinical pharmacology and therapeutics, 1999, Volume: 65, Issue:4

    Topics: Adult; Anti-Anxiety Agents; Antitussive Agents; Aryl Hydrocarbon Hydroxylases; Benzenesulfonates; Caffeine; Central Nervous System Stimulants; Cimetidine; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Dextromethorphan; Double-Blind Method; Histamine H2 Antagonists; Humans; In Vitro Techniques; Male; Methylation; Microsomes, Liver; Midazolam; Oxidoreductases, N-Demethylating; Psychomotor Performance; Ranitidine; Thiazoles

1999

Other Studies

14 other study(ies) available for ebrotidine and ranitidine

ArticleYear
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Gastroprotective and ulcer-healing activities of a new H2-receptor antagonist: ebrotidine.
    Digestion, 1992, Volume: 51, Issue:1

    Topics: Acetates; Acetic Acid; Animals; Benzenesulfonates; Epidermal Growth Factor; Ethanol; Gastric Acid; Gastric Mucosa; Gastrins; Histamine H2 Antagonists; Male; Ranitidine; Rats; Rats, Inbred Strains; Regional Blood Flow; Stomach Ulcer; Thiazoles

1992
Enhancement of gastric mucus phospholipid secretion by an antiulcer agent, ebrotidine.
    General pharmacology, 1994, Volume: 25, Issue:5

    Topics: Animals; Anti-Ulcer Agents; Benzenesulfonates; Choline; Cyclic AMP; Gastric Mucosa; Male; Mucus; Phospholipids; Ranitidine; Rats; Rats, Sprague-Dawley; Thiazoles

1994
Effect of ebrotidine on gastric mucosal EGF and PDGF receptor expression.
    Biochemistry and molecular biology international, 1993, Volume: 30, Issue:6

    Topics: Animals; Benzenesulfonates; Cell Membrane; Epidermal Growth Factor; ErbB Receptors; Gastric Mucosa; Histamine H2 Antagonists; Phosphorylation; Platelet-Derived Growth Factor; Ranitidine; Rats; Receptors, Platelet-Derived Growth Factor; Thiazoles; Tyrosine

1993
Inhibition of Helicobacter pylori urease activity by ebrotidine.
    Biochemistry and molecular biology international, 1995, Volume: 37, Issue:2

    Topics: Anti-Ulcer Agents; Benzenesulfonates; Dose-Response Relationship, Drug; Helicobacter pylori; Ranitidine; Thiazoles; Urease

1995
Susceptibility of Helicobacter pylori to antimicrobial agents: effect of ebrotidine and ranitidine.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 1995, Volume: 46, Issue:4

    Topics: Anti-Bacterial Agents; Benzenesulfonates; Drug Interactions; Helicobacter pylori; Histamine H2 Antagonists; Microbial Sensitivity Tests; Ranitidine; Thiazoles

1995
Histamine H2-receptor antagonist action of ebrotidine. Effects on gastric acid secretion, gastrin levels and NSAID-induced gastrotoxicity in the rat.
    Arzneimittel-Forschung, 1997, Volume: 47, Issue:4A

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzenesulfonates; Diclofenac; Dose-Response Relationship, Drug; Female; Gastric Acid; Gastrins; Guinea Pigs; Heart Atria; Heart Rate; Histamine; Histamine H2 Antagonists; In Vitro Techniques; Indomethacin; Ketoprofen; Male; Naproxen; Pentagastrin; Ranitidine; Rats; Rats, Sprague-Dawley; Rats, Wistar; Thiazoles

1997
Action of ebrotidine, ranitidine and cimetidine on the specific binding to histamine H1- and H2-receptors.
    Arzneimittel-Forschung, 1997, Volume: 47, Issue:4A

    Topics: Animals; Benzenesulfonates; Cell Membrane; Cerebellum; Cerebral Cortex; Cimetidine; Depression, Chemical; Guinea Pigs; Histamine H2 Antagonists; In Vitro Techniques; Isotope Labeling; Male; Protein Binding; Pyrilamine; Ranitidine; Receptors, Histamine H1; Receptors, Histamine H2; Thiazoles; Tritium

1997
Effect of ebrotidine on ethanol-induced gastric mucosal damage in the rat. Comparative study with other H2-receptor antagonists.
    Arzneimittel-Forschung, 1997, Volume: 47, Issue:4A

    Topics: Animals; Benzenesulfonates; Cimetidine; Dose-Response Relationship, Drug; Ethanol; Famotidine; Female; Gastric Mucosa; Histamine H2 Antagonists; Indomethacin; Peptic Ulcer; Ranitidine; Rats; Rats, Sprague-Dawley; Thiazoles

1997
In vitro anti-Helicobacter pylori activity of ebrotidine.
    Arzneimittel-Forschung, 1997, Volume: 47, Issue:4A

    Topics: Amoxicillin; Benzenesulfonates; Clarithromycin; Drug Synergism; Erythromycin; Helicobacter pylori; Histamine H2 Antagonists; Metronidazole; Microbial Sensitivity Tests; Ranitidine; Tetracycline; Thiazoles

1997
Comparative study of plasma gastrin levels in rats after two months of ebrotidine administration.
    Arzneimittel-Forschung, 1997, Volume: 47, Issue:4A

    Topics: Animals; Benzenesulfonates; Cimetidine; Gastrins; Histamine H2 Antagonists; Male; Omeprazole; Ranitidine; Rats; Rats, Sprague-Dawley; Specific Pathogen-Free Organisms; Thiazoles

1997
In vitro activity of ebrotidine, ranitidine, omeprazole, lansoprazole, and bismuth citrate against clinical isolates of Helicobacter pylori.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1998, Volume: 17, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Bacterial Agents; Anti-Ulcer Agents; Benzenesulfonates; Helicobacter pylori; Lansoprazole; Microbial Sensitivity Tests; Omeprazole; Organometallic Compounds; Ranitidine; Thiazoles

1998
Endothelin-1, interleukin-4 and nitric oxide synthase modulators of gastric mucosal injury by indomethacin: effect of antiulcer agents.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 1999, Volume: 50, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Apoptosis; Benzenesulfonates; Endothelin-1; Gastric Mucosa; Indomethacin; Interleukin-4; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Ranitidine; Rats; Rats, Sprague-Dawley; Sialoglycoproteins; Stomach Ulcer; Thiazoles

1999
Prevention and healing of experimental indomethacin-induced gastric lesions: effects of ebrotidine, omeprazole and ranitidine.
    European journal of gastroenterology & hepatology, 2000, Volume: 12, Issue:3

    Topics: Animals; Anti-Ulcer Agents; Benzenesulfonates; Disease Models, Animal; Gastric Juice; Histamine H2 Antagonists; Indomethacin; Male; Omeprazole; Ranitidine; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Thiazoles

2000