ebastine and ketoconazole

ebastine has been researched along with ketoconazole in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (50.00)18.2507
2000's2 (25.00)29.6817
2010's2 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nagashima, R; Nishikawa, T; Tobita, M1
Sen, S; Sinha, N1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
del Prado, M; Egan, RW; Hey, JA; Kreutner, W1
Llenas, J; Roberts, DJ1
del Prado, M; Egan, RW; Hey, JA; Kreutner, W; Sherwood, J1
Chaikin, P; Garcia, JD; Gillen, M; Morganroth, J; Moss, AJ; Roberts, DJ1
Chaikin, P; Gillen, MS; Malik, M; Pentikis, H; Rhodes, GR; Roberts, DJ1

Reviews

1 review(s) available for ebastine and ketoconazole

ArticleYear
A review of the cardiac systemic side-effects of antihistamines: ebastine.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1999, Volume: 29 Suppl 3

    Topics: Adult; Butyrophenones; Child; Clinical Trials as Topic; Drug Interactions; Erythromycin; Heart; Histamine H1 Antagonists; Humans; Ketoconazole; Piperidines

1999

Trials

1 trial(s) available for ebastine and ketoconazole

ArticleYear
Co-administration of ketoconazole with H1-antagonists ebastine and loratadine in healthy subjects: pharmacokinetic and pharmacodynamic effects.
    British journal of clinical pharmacology, 2005, Volume: 59, Issue:3

    Topics: Adolescent; Adult; Antifungal Agents; Butyrophenones; Double-Blind Method; Drug Combinations; Electrocardiography; Heart Rate; Histamine H1 Antagonists; Humans; Ketoconazole; Loratadine; Male; Piperidines

2005

Other Studies

6 other study(ies) available for ebastine and ketoconazole

ArticleYear
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
    Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11

    Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated

2005
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Cardiotoxic and drug interaction profile of the second generation antihistamines ebastine and terfenadine in an experimental animal model of torsade de pointes.
    Arzneimittel-Forschung, 1996, Volume: 46, Issue:2

    Topics: Animals; Butyrophenones; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Electrocardiography; Guinea Pigs; Heart Diseases; Histamine H1 Antagonists; Ketoconazole; Liver; Male; Mixed Function Oxygenases; Piperidines; Terfenadine; Torsades de Pointes

1996
Some observations on the cardiotoxic and drug interaction profiles of second generation antihistamines as measured in the guinea pig.
    Arzneimittel-Forschung, 1996, Volume: 46, Issue:8

    Topics: Animals; Antifungal Agents; Butyrophenones; Disease Models, Animal; Drug Interactions; Electrocardiography; Guinea Pigs; Histamine H1 Antagonists; Injections, Intravenous; Ketoconazole; Piperidines; Terfenadine; Torsades de Pointes

1996
The guinea pig model for assessing cardiotoxic proclivities of second generation antihistamines.
    Arzneimittel-Forschung, 1996, Volume: 46, Issue:8

    Topics: Animals; Antifungal Agents; Butyrophenones; Cats; Disease Models, Animal; Drug Interactions; Guinea Pigs; Histamine H1 Antagonists; Humans; Ketoconazole; Piperidines; Terfenadine; Torsades de Pointes

1996