ebastine and ketoconazole
ebastine has been researched along with ketoconazole in 8 studies
Research
Studies (8)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (50.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Nagashima, R; Nishikawa, T; Tobita, M | 1 |
| Sen, S; Sinha, N | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| del Prado, M; Egan, RW; Hey, JA; Kreutner, W | 1 |
| Llenas, J; Roberts, DJ | 1 |
| del Prado, M; Egan, RW; Hey, JA; Kreutner, W; Sherwood, J | 1 |
| Chaikin, P; Garcia, JD; Gillen, M; Morganroth, J; Moss, AJ; Roberts, DJ | 1 |
| Chaikin, P; Gillen, MS; Malik, M; Pentikis, H; Rhodes, GR; Roberts, DJ | 1 |
Reviews
1 review(s) available for ebastine and ketoconazole
| Article | Year |
|---|---|
A review of the cardiac systemic side-effects of antihistamines: ebastine.
Topics: Adult; Butyrophenones; Child; Clinical Trials as Topic; Drug Interactions; Erythromycin; Heart; Histamine H1 Antagonists; Humans; Ketoconazole; Piperidines | 1999 |
Trials
1 trial(s) available for ebastine and ketoconazole
| Article | Year |
|---|---|
Co-administration of ketoconazole with H1-antagonists ebastine and loratadine in healthy subjects: pharmacokinetic and pharmacodynamic effects.
Topics: Adolescent; Adult; Antifungal Agents; Butyrophenones; Double-Blind Method; Drug Combinations; Electrocardiography; Heart Rate; Histamine H1 Antagonists; Humans; Ketoconazole; Loratadine; Male; Piperidines | 2005 |
Other Studies
6 other study(ies) available for ebastine and ketoconazole
| Article | Year |
|---|---|
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated | 2005 |
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Cardiotoxic and drug interaction profile of the second generation antihistamines ebastine and terfenadine in an experimental animal model of torsade de pointes.
Topics: Animals; Butyrophenones; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Electrocardiography; Guinea Pigs; Heart Diseases; Histamine H1 Antagonists; Ketoconazole; Liver; Male; Mixed Function Oxygenases; Piperidines; Terfenadine; Torsades de Pointes | 1996 |
Some observations on the cardiotoxic and drug interaction profiles of second generation antihistamines as measured in the guinea pig.
Topics: Animals; Antifungal Agents; Butyrophenones; Disease Models, Animal; Drug Interactions; Electrocardiography; Guinea Pigs; Histamine H1 Antagonists; Injections, Intravenous; Ketoconazole; Piperidines; Terfenadine; Torsades de Pointes | 1996 |
The guinea pig model for assessing cardiotoxic proclivities of second generation antihistamines.
Topics: Animals; Antifungal Agents; Butyrophenones; Cats; Disease Models, Animal; Drug Interactions; Guinea Pigs; Histamine H1 Antagonists; Humans; Ketoconazole; Piperidines; Terfenadine; Torsades de Pointes | 1996 |