ebastine and histamine

ebastine has been researched along with histamine in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (41.18)18.2507
2000's7 (41.18)29.6817
2010's2 (11.76)24.3611
2020's1 (5.88)2.80

Authors

AuthorsStudies
Bakker, RA; Leurs, R; Lim, HD; Ling, P; Thurmond, RL; van Rijn, RM1
Despontin, K; Ghys, L; Lachapelle, JM; Rihoux, JP; Rivest, J1
Holgate, ST; Wood-Baker, R1
Ter Laak, AM; Timmerman, H; Walczynski, K; Zhang, MQ1
de la Cuadra, J; Roma, J; Teixidó, P; Teruel, M1
Benabdesselam, O; Frossard, N; Melac, M; Pauli, G1
Leroy, T; Tasset, C; Valentin, B; Van Neste, D1
Danielson, L; DeVos, C; Grant, JA; Rihoux, JP1
DeVos, C; Grant, JA; Moulaert, B; Riethuisen, JM1
Gras, J; Llenas, J; Llupià, J1
Boyce, M; Carey, W; Luria, X; Warrington, S1
Antonijoan, RM; Barbanoj, MJ; Esbri, R; Fortea, J; García-Gea, C; Puntes, M; Valle, M1
Antonijoan, R; Barbanoj, MJ; Esbrí, R; Fortea, J; García-Gea, C; Pérez, J; Puntes, M; Serra, C1
Devillier, P1
Cha, IJ; Lee, SS; Liu, KH; Shin, JG; Shon, JH; Yeo, CW1
Cauley, M; Cousins, V; Hampton, D; Levin, ED; Petro, A; Pruitt, M; Rose, J; Slade, S; Wells, C1
Sastre, J1

Reviews

1 review(s) available for ebastine and histamine

ArticleYear
Ebastine in the Treatment of Allergic Rhinitis and Urticaria: 30 Years of Clinical Studies and Real-World Experience.
    Journal of investigational allergology & clinical immunology, 2020, Volume: 30, Issue:3

    Topics: Administration, Oral; Butyrophenones; Histamine; Histamine H1 Antagonists; Humans; Piperidines; Rhinitis, Allergic; Treatment Outcome; Urticaria

2020

Trials

11 trial(s) available for ebastine and histamine

ArticleYear
Pharmacological modulation by cetirizine and ebastine of the cutaneous reactivity to histamine.
    Dermatologica, 1991, Volume: 183, Issue:3

    Topics: Administration, Cutaneous; Administration, Oral; Adult; Butyrophenones; Capsules; Cetirizine; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; Hypersensitivity; Male; Multivariate Analysis; Piperidines; Placebos; Skin; Skin Tests; Time Factors

1991
Dose-response relationship of the H1-histamine antagonist, ebastine, against histamine and methacholine-induced bronchoconstriction in patients with asthma.
    Agents and actions, 1990, Volume: 30, Issue:1-2

    Topics: Adult; Asthma; Bronchi; Butyrophenones; Dose-Response Relationship, Drug; Female; Forced Expiratory Volume; Histamine; Histamine H1 Antagonists; Humans; Male; Methacholine Compounds; Middle Aged; Piperidines

1990
Assessment of the wheal size and skin blood flow of the erythema induced by histamine and its modification with cetirizine and ebastine: a crossover, double-blind study.
    Dermatology (Basel, Switzerland), 1994, Volume: 188, Issue:2

    Topics: Adolescent; Adult; Butyrophenones; Cetirizine; Double-Blind Method; Erythema; Female; Histamine; Histamine H1 Antagonists; Humans; Laser-Doppler Flowmetry; Male; Piperidines; Prospective Studies; Regional Blood Flow; Skin

1994
Consistency of the efficacy of cetirizine and ebastine on skin reactivity.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 1998, Volume: 80, Issue:1

    Topics: Adult; Anaphylaxis; Butyrophenones; Cetirizine; Cross-Over Studies; Dermatitis, Allergic Contact; Dose-Response Relationship, Drug; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists; Humans; Male; Piperidines; Safety; Skin; Skin Tests

1998
Comparison of the effects of cetirizine and ebastine on the skin response to histamine iontophoresis monitored with laser Doppler flowmetry.
    Dermatology (Basel, Switzerland), 1998, Volume: 197, Issue:2

    Topics: Adult; Butyrophenones; Cetirizine; Cross-Over Studies; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists; Humans; Iontophoresis; Laser-Doppler Flowmetry; Male; Piperidines; Skin; Skin Diseases; Skin Tests; Time Factors

1998
A double-blind, single-dose, crossover comparison of cetirizine, ebastine, epinastine, fexofenadine, terfenadine, and loratadine versus placebo: suppression of histamine-induced wheal and flare response for 24 h in healthy male subjects.
    Allergy, 1999, Volume: 54, Issue:7

    Topics: Adult; Butyrophenones; Cetirizine; Cross-Over Studies; Dibenzazepines; Double-Blind Method; Histamine; Histamine H1 Antagonists; Histamine Release; Humans; Hypersensitivity, Immediate; Imidazoles; Loratadine; Male; Piperidines; Skin Tests; Terfenadine; Urticaria

1999
A double-blind, randomized, single-dose, crossover comparison of levocetirizine with ebastine, fexofenadine, loratadine, mizolastine, and placebo: suppression of histamine-induced wheal-and-flare response during 24 hours in healthy male subjects.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2002, Volume: 88, Issue:2

    Topics: Adult; Benzimidazoles; Butyrophenones; Cetirizine; Cross-Over Studies; Double-Blind Method; Histamine; Histamine H1 Antagonists; Humans; Loratadine; Male; Piperidines; Terfenadine; Treatment Outcome; Urticaria

2002
Inhibition of the histamine wheal by ebastine compared with cetirizine, fexofenadine and loratadine at steady state.
    Drugs under experimental and clinical research, 2002, Volume: 28, Issue:6

    Topics: Adolescent; Adult; Butyrophenones; Cetirizine; Cross-Over Studies; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists; Humans; Hypersensitivity, Immediate; Injections, Intradermal; Loratadine; Male; Piperidines; Skin Tests; Terfenadine

2002
A comparison of ebastine 10 mg fast-dissolving tablet with oral desloratadine and placebo in inhibiting the cutaneous reaction to histamine in healthy adults.
    Clinical drug investigation, 2007, Volume: 27, Issue:7

    Topics: Adult; Butyrophenones; Chemistry, Pharmaceutical; Dermatitis, Contact; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists; Humans; Loratadine; Male; Pain Measurement; Patient Acceptance of Health Care; Piperidines; Skin; Tablets; Treatment Outcome

2007
Comparison of inhibition of cutaneous histamine reaction of ebastine fast-dissolving tablet (20 mg) versus desloratadine capsule (5 mg): a randomized, double-blind, double-dummy, placebo-controlled, three-period crossover study in healthy, nonatopic adult
    Clinical therapeutics, 2007, Volume: 29, Issue:5

    Topics: Adolescent; Adult; Butyrophenones; Cross-Over Studies; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists; Humans; Loratadine; Male; Pain Measurement; Piperidines; Pruritus; Skin; Skin Tests

2007
Itraconazole and rifampin alter significantly the disposition and antihistamine effect of ebastine and its metabolites in healthy participants.
    Journal of clinical pharmacology, 2010, Volume: 50, Issue:2

    Topics: Adult; Antifungal Agents; Butyrophenones; Cross-Over Studies; Drug Interactions; Enzyme Inhibitors; Histamine; Histamine H1 Antagonists; Humans; Hypersensitivity, Immediate; Itraconazole; Male; Piperidines; Rifampin; Skin; Young Adult

2010

Other Studies

5 other study(ies) available for ebastine and histamine

ArticleYear
Evaluation of histamine H1-, H2-, and H3-receptor ligands at the human histamine H4 receptor: identification of 4-methylhistamine as the first potent and selective H4 receptor agonist.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 314, Issue:3

    Topics: Cell Line; Histamine Agonists; Humans; Imidazoles; Indoles; Isothiuronium; Ligands; Methylhistamines; Piperazines; Radioligand Assay; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Receptors, Histamine H3; Receptors, Histamine H4

2005
Optically active analogues of ebastine: synthesis and effect of chirality on their antihistaminic and antimuscarinic activity.
    Chirality, 1994, Volume: 6, Issue:8

    Topics: Animals; Butyrophenones; Guinea Pigs; Histamine; Histamine H1 Antagonists; Ileum; In Vitro Techniques; Models, Molecular; Muscarinic Antagonists; Piperidines; Receptors, Histamine H1; Receptors, Muscarinic; Stereoisomerism

1994
Comparative antiallergic effects of second-generation H1-antihistamines ebastine, cetirizine and loratadine in preclinical models.
    Arzneimittel-Forschung, 2003, Volume: 53, Issue:2

    Topics: Aerosols; Airway Resistance; Algorithms; Animals; Anti-Allergic Agents; Bronchial Spasm; Butyrophenones; Cetirizine; Guinea Pigs; Histamine; Histamine H1 Antagonists; Leukotriene C4; Loratadine; Male; Ovalbumin; Piperidines

2003
Comparison of inhibition of cutaneous histamine reaction of ebastine fast-dissolving tablet [20 mg] versus desloratadine capsule [5 mg]: a randomized, double-blind, double-dummy, placebo-controlled, three-period crossover study in healthy, nonatopic adult
    Clinical therapeutics, 2007, Volume: 29, Issue:12

    Topics: Butyrophenones; Histamine; Histamine H1 Antagonists; Humans; Loratadine; Piperidines; Randomized Controlled Trials as Topic; Skin Tests

2007
Histamine H(1) antagonist treatment with pyrilamine reduces nicotine self-administration in rats.
    European journal of pharmacology, 2011, Jan-10, Volume: 650, Issue:1

    Topics: Animals; Butyrophenones; Drug Administration Schedule; Female; Follow-Up Studies; Food; Histamine; Histamine H1 Antagonists; Infusion Pumps; Injections; Motivation; Nicotine; Piperidines; Pyrilamine; Rats; Rats, Sprague-Dawley; Self Administration; Tobacco Use Disorder

2011