Compounds > ebastine

ebastine and arachidonic acid

ebastine has been researched along with arachidonic acid in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (80.00)29.6817
2010's0 (0.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Fujii, T; Funae, Y; Hashizume, T; Hiroi, T; Imaoka, S; Kamataki, T; Miyazaki, H; Terauchi, Y1
Fujii, T; Funae, Y; Hashizume, T; Imaoka, S; Kamataki, T; Mise, M; Miyazaki, H; Terauchi, Y1
Hirama, T; Matsubara, T; Matsumoto, S; Nagata, K; Yamazoe, Y1
Bridges, AS; Hall, JE; Kornbluth, S; Paine, MF; Tidwell, RR; Wang, MZ; Wu, JQ; Zeldin, DC1
Chen, LY; Xu, L1

Other Studies

5 other study(ies) available for ebastine and arachidonic acid

ArticleYear
cDNA cloning and expression of a novel cytochrome p450 (cyp4f12) from human small intestine.
    Biochemical and biophysical research communications, 2001, Feb-02, Volume: 280, Issue:4

    Topics: Amino Acid Sequence; Arachidonic Acid; Aryl Hydrocarbon Hydroxylases; Base Sequence; Butyrophenones; Catalysis; Cloning, Molecular; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 4; DNA, Complementary; Gene Library; Humans; Intestine, Small; Leukotriene B4; Liver; Mixed Function Oxygenases; Molecular Sequence Data; Piperidines; Protein Isoforms; Reverse Transcriptase Polymerase Chain Reaction; Saccharomyces cerevisiae; Sequence Analysis, DNA; Sequence Homology, Amino Acid

2001
Involvement of CYP2J2 and CYP4F12 in the metabolism of ebastine in human intestinal microsomes.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 300, Issue:1

    Topics: Antibodies, Blocking; Arachidonic Acid; Aryl Hydrocarbon Hydroxylases; Butyrophenones; Cloning, Molecular; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dealkylation; Enzyme Inhibitors; Histamine H1 Antagonists; Humans; In Vitro Techniques; Intestinal Mucosa; Intestines; Kinetics; Leukotriene B4; Microsomes; Mixed Function Oxygenases; Oxygenases; Piperidines; Recombinant Proteins

2002
Involvement of CYP2J2 on the intestinal first-pass metabolism of antihistamine drug, astemizole.
    Drug metabolism and disposition: the biological fate of chemicals, 2002, Volume: 30, Issue:11

    Topics: Animals; Antibodies, Blocking; Arachidonic Acid; Astemizole; Blotting, Western; Butyrophenones; Chlorocebus aethiops; Chromatography, High Pressure Liquid; Cloning, Molecular; COS Cells; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dealkylation; DNA, Complementary; Enzyme Inhibitors; Gene Library; Histamine H1 Antagonists; Humans; In Vitro Techniques; Intestinal Mucosa; Mass Spectrometry; Microsomes, Liver; Oxygenases; Piperidines; Rabbits; Recombinant Proteins

2002
Human enteric microsomal CYP4F enzymes O-demethylate the antiparasitic prodrug pafuramidine.
    Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:11

    Topics: Amidines; Antibodies; Antiparasitic Agents; Arachidonic Acid; Benzamidines; Benzoflavones; Butyrophenones; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 4; Enzyme Inhibitors; Fatty Acids, Unsaturated; Humans; Hydroxyeicosatetraenoic Acids; Intestinal Mucosa; Intestines; Kinetics; Methylation; Microsomes; Oxygenases; Piperidines; Prodrugs; Recombinant Proteins; Stereoisomerism

2007
Molecular determinant of substrate binding and specificity of cytochrome P450 2J2.
    Scientific reports, 2020, 12-17, Volume: 10, Issue:1

    Topics: Arachidonic Acid; Astemizole; Butyrophenones; Catalytic Domain; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Humans; Hydrophobic and Hydrophilic Interactions; Kinetics; Molecular Docking Simulation; Oxidation-Reduction; Piperidines; Protein Binding; Substrate Specificity

2020