e 4031 has been researched along with quinidine in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (13.64) | 18.2507 |
| 2000's | 11 (50.00) | 29.6817 |
| 2010's | 7 (31.82) | 24.3611 |
| 2020's | 1 (4.55) | 2.80 |
| Authors | Studies |
|---|---|
| Keserü, GM | 1 |
| Nagashima, R; Nishikawa, T; Tobita, M | 1 |
| Bianucci, AM; Calderone, V; Coi, A; Massarelli, I; Testai, L | 1 |
| Jia, L; Sun, H | 1 |
| Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B | 1 |
| Bracke, ME; De Ryck, T; Katritzky, AR; Patronov, A; Roman, BI; Slavov, SH; Stevens, CV; Vanhoecke, BW | 1 |
| Andréola, ML; Bailly, F; Billamboz, M; Christ, F; Cotelle, P; Debyser, Z; Lion, C; Suchaud, V | 1 |
| Kovalenko, A; Krasavin, M; Lukin, A; Moore, D; Tikhonova, IG; Zahanich, I; Zhurilo, N; Zozulya, S | 1 |
| Bae, S; Cho, Y; Choi, J; Kang, JA; Kim, YC; Lee, D; Lim, C; Park, M; Park, SG; Seo, J | 1 |
| Grundke, M; Ravens, U; Wettwer, E | 1 |
| Ishii, K; Taira, N; Yamagishi, T | 1 |
| Asano, Y; Baxter, WT; Davidenko, JM; Gray, RA; Jalife, J | 1 |
| Danilo, P; de Groot, JR; Feinmark, S; Gainullin, R; Plotnikov, AN; Rosen, MR; Rosenshtraukh, L; Shvilkin, A; Xiong, W | 1 |
| Fukuda, K; Kato, T; Kodama, H; Miyoshi, S; Ogawa, S; Tahara, S | 1 |
| Brown, AM; Ficker, E; Obejero-Paz, CA; Zhao, S | 1 |
| Colas, A; Pages, N; Sauviat, MP | 1 |
| Pan, YP; Wang, XL; Xu, XH | 1 |
| Chan, AP; Guppy, LJ; Leung, MW; So, PP; Walker, MJ | 1 |
| Abe, J; Hamada, Y; Harada, T; Hashimoto, K; Horii, I; Sawada, Y; Shiotani, M | 1 |
| Ma, J; Song, Z; Wang, J; Wang, S; Wang, X; Zhao, Q | 1 |
| Luo, C; Wang, K; Zhang, H | 2 |
22 other study(ies) available for e 4031 and quinidine
| Article | Year |
|---|---|
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship | 2003 |
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated | 2005 |
Identification of "toxicophoric" features for predicting drug-induced QT interval prolongation.
Topics: Amino Acid Sequence; Heart; Humans; Models, Molecular; Molecular Sequence Data; Molecular Structure; Protein Subunits; Sequence Alignment; Structure-Activity Relationship; Trans-Activators; Transcriptional Regulator ERG | 2008 |
Support vector machines classification of hERG liabilities based on atom types.
Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve | 2008 |
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.
Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers | 2012 |
4-Fluoro-3',4',5'-trimethoxychalcone as a new anti-invasive agent. From discovery to initial validation in an in vivo metastasis model.
Topics: Animals; Antineoplastic Agents, Phytogenic; Biological Products; Cell Line, Tumor; Cell Movement; Cell Survival; Chalcones; Chick Embryo; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Discovery; Female; Humans; Mice; Mice, Nude; Molecular Structure; Myocardium; Neoplasm Invasiveness; Neoplasm Metastasis; Quantitative Structure-Activity Relationship | 2015 |
2-hydroxyisoquinoline-1,3(2H,4H)-diones (HIDs) as human immunodeficiency virus type 1 integrase inhibitors: Influence of the alkylcarboxamide substitution of position 4.
Topics: Alkylation; Anti-HIV Agents; Cell Line; Drug Resistance, Viral; HIV Integrase Inhibitors; Humans; Isoquinolines; Structure-Activity Relationship | 2016 |
Novel free fatty acid receptor 1 (GPR40) agonists based on 1,3,4-thiadiazole-2-carboxamide scaffold.
Topics: Amides; Animals; Drug Delivery Systems; Humans; Hypoglycemic Agents; Mice; Microsomes, Liver; Molecular Docking Simulation; Protein Binding; Receptors, G-Protein-Coupled; Thiadiazoles | 2016 |
Entry inhibition of hepatitis B virus using cyclosporin O derivatives with peptoid side chain incorporation.
Topics: Antiviral Agents; Cyclosporins; Hepatitis B; Hepatitis B virus; Humans; Imidazoles; Liver Neoplasms; Organic Anion Transporters, Sodium-Dependent; Peptoids; Sulfonamides; Symporters; Thiophenes; Virus Internalization | 2022 |
Differential effects of the new class III antiarrhythmic agents almokalant, E-4031 and D-sotalol, and of quinidine, on delayed rectifier currents in guinea pig ventricular myocytes.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Guinea Pigs; In Vitro Techniques; Muscles; Piperidines; Potassium; Potassium Channels; Propanolamines; Pyridines; Quinidine; Sotalol; Time Factors | 1992 |
Absence of effects of class III antiarrhythmic agents on cloned cardiac K channels.
Topics: 4-Aminopyridine; Animals; Anti-Arrhythmia Agents; Cloning, Molecular; Electrophysiology; Myocardium; Oocytes; Piperidines; Potassium Channels; Pyridines; Pyrimidinones; Quinidine; Sotalol; Xenopus laevis | 1993 |
Optical mapping of drug-induced polymorphic arrhythmias and torsade de pointes in the isolated rabbit heart.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Electrocardiography; Heart; Heart Conduction System; Image Processing, Computer-Assisted; Models, Cardiovascular; Organ Culture Techniques; Perfusion; Piperidines; Pyridines; Quinidine; Rabbits; Torsades de Pointes | 1997 |
Interactions between antiarrhythmic drugs and cardiac memory.
Topics: Animals; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Dogs; Electrocardiography; Electrophysiology; Feedback; Lidocaine; Piperidines; Potassium Channels; Pyridines; Quinidine | 2001 |
Potassium channel blocker activates extracellular signal-regulated kinases through Pyk2 and epidermal growth factor receptor in rat cardiomyocytes.
Topics: 4-Aminopyridine; Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium Channels, L-Type; Cells, Cultured; Cytochalasin D; Drug Evaluation, Preclinical; ErbB Receptors; Focal Adhesion Kinase 2; Mitogen-Activated Protein Kinases; Myocardium; Phosphorylation; Piperidines; Potassium Channel Blockers; Protein-Tyrosine Kinases; Pyridines; Quinazolines; Quinidine; Rats; Rats, Wistar; Tetraethylammonium; Time Factors; Tyrphostins | 2001 |
The binding site for channel blockers that rescue misprocessed human long QT syndrome type 2 ether-a-gogo-related gene (HERG) mutations.
Topics: Anti-Arrhythmia Agents; Astemizole; Benzimidazoles; Binding Sites; Blotting, Western; Cation Transport Proteins; Cell Line; Cell Membrane; Cisapride; DNA-Binding Proteins; Dose-Response Relationship, Drug; Electrophysiology; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Gastrointestinal Agents; Histamine H1 Antagonists; Humans; Inhibitory Concentration 50; Ions; Long QT Syndrome; Models, Chemical; Mutagenesis, Site-Directed; Mutation; Patch-Clamp Techniques; Piperidines; Potassium Channels; Potassium Channels, Voltage-Gated; Protein Folding; Pyridines; Quaternary Ammonium Compounds; Quinidine; Structure-Activity Relationship; Trans-Activators; Transcriptional Regulator ERG | 2002 |
Does lindane (gamma-hexachlorocyclohexane) increase the rapid delayed rectifier outward K+ current (IKr) in frog atrial myocytes?
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Delayed Rectifier Potassium Channels; Electrophysiology; Heart Atria; Hexachlorocyclohexane; Myocardium; Myocytes, Cardiac; Piperidines; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Pyridines; Quinidine; Ranidae | 2002 |
[High throughput screening method of potassium channel regulators].
Topics: 4-Aminopyridine; Animals; Barbiturates; Calcium Channel Blockers; Cromakalim; Isoxazoles; Membrane Potentials; Nifedipine; Patch-Clamp Techniques; PC12 Cells; Piperidines; Potassium Channel Blockers; Potassium Channels; Pyridines; Quinidine; Rats | 2004 |
Effects of E4031 and quinidine on atrial and ventricular refractoriness in rabbits in vivo.
Topics: Animals; Anti-Arrhythmia Agents; Atrioventricular Node; Blood Pressure; Dose-Response Relationship, Drug; Evoked Potentials; Heart Atria; Heart Ventricles; Piperidines; Pyridines; Quinidine; Rabbits; Refractory Period, Electrophysiological; Sinoatrial Node | 2004 |
Practical application of guinea pig telemetry system for QT evaluation.
Topics: Animals; Anti-Arrhythmia Agents; Antipsychotic Agents; Bepridil; Cisapride; Disease Models, Animal; Electrocardiography; Guinea Pigs; Haloperidol; Heart; Humans; Injections, Intravenous; Long QT Syndrome; Male; Nifedipine; Pimozide; Piperidines; Pyridines; Quinidine; Reproducibility of Results; Telemetry; Terfenadine; Thioridazine | 2005 |
Cardiotoxicity evaluation using human embryonic stem cells and induced pluripotent stem cell-derived cardiomyocytes.
Topics: Cardiotoxicity; Cell Differentiation; Drug Discovery; Haloperidol; Human Embryonic Stem Cells; Humans; Induced Pluripotent Stem Cells; Isoproterenol; Myocytes, Cardiac; Piperidines; Pyridines; Quinidine | 2017 |
In silico assessment of the effects of quinidine, disopyramide and E-4031 on short QT syndrome variant 1 in the human ventricles.
Topics: Action Potentials; Arrhythmias, Cardiac; Cell Line; Disopyramide; Electrocardiography; ERG1 Potassium Channel; Heart Ventricles; Humans; Models, Biological; Piperidines; Polymorphism, Single Nucleotide; Pyridines; Quinidine | 2017 |
Modelling the effects of quinidine, disopyramide, and E-4031 on short QT syndrome variant 3 in the human ventricles.
Topics: Action Potentials; Arrhythmias, Cardiac; Disopyramide; Heart Conduction System; Heart Defects, Congenital; Heart Ventricles; Humans; Models, Biological; Piperidines; Pyridines; Quinidine | 2017 |