e 4031 has been researched along with nifekalant hydrochloride in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (90.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kanno, M; Nakaya, H; Tohse, N | 1 |
| Hara, Y; Masuda, Y; Mori, K; Nakaya, H; Saito, T | 1 |
| Ishii, K; Taira, N; Yamagishi, T | 1 |
| Mitamura, H; Ogawa, S; Okada, Y; Sadanaga, T | 1 |
| Hashimoto, K; Motomura, S; Yamada, A | 1 |
| Cheng, J; Kamiya, K; Kodama, I; Toyama, J | 1 |
| Masuda, Y; Mori, K; Nakaya, H; Saito, T | 1 |
| Aizawa, Y; Naitoh, N; Takahashi, K; Washizuka, T | 1 |
| Aizawa, Y; Furushima, H; Naitoh, N; Tagawa, M; Taneda, K; Yamaura, M | 1 |
| Fujii, M; Imaizumi, Y; Ohya, S; Yamamura, H | 1 |
1 trial(s) available for e 4031 and nifekalant hydrochloride
| Article | Year |
|---|---|
Assessment of reverse use-dependent blocking actions of class III antiarrhythmic drugs by 24-hour Holter electrocardiography.
Topics: Adult; Aged; Analysis of Variance; Anti-Arrhythmia Agents; Electrocardiography, Ambulatory; Female; Humans; Long QT Syndrome; Male; Middle Aged; Phenethylamines; Piperidines; Pyridines; Pyrimidinones; Regression Analysis; Sotalol; Statistics, Nonparametric; Sulfonamides | 1996 |
9 other study(ies) available for e 4031 and nifekalant hydrochloride
| Article | Year |
|---|---|
[Electropharmacological properties of class III antiarrhythmic drugs].
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Heart; In Vitro Techniques; Piperidines; Pyridines; Pyrimidinones; Rabbits | 1994 |
Anticholinergic effects of class III antiarrhythmic drugs in guinea pig atrial cells. Different molecular mechanisms.
Topics: Acetylcholine; Action Potentials; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Atrial Function, Left; Cells, Cultured; Guinea Pigs; Heart Atria; In Vitro Techniques; Myocardial Contraction; Patch-Clamp Techniques; Piperidines; Potassium Channels; Pyridines; Pyrimidinones; Receptors, Muscarinic; Sotalol | 1995 |
Absence of effects of class III antiarrhythmic agents on cloned cardiac K channels.
Topics: 4-Aminopyridine; Animals; Anti-Arrhythmia Agents; Cloning, Molecular; Electrophysiology; Myocardium; Oocytes; Piperidines; Potassium Channels; Pyridines; Pyrimidinones; Quinidine; Sotalol; Xenopus laevis | 1993 |
Comparison of direct negative chronotropic and positive inotropic effects of sematilide to those of E-4031 and MS-551 and the reverse frequency-dependent prolongation of cardiac refractoriness of sematilide.
Topics: Animals; Anti-Arrhythmia Agents; Atrioventricular Node; Dogs; Female; Heart Rate; Male; Papillary Muscles; Piperidines; Procainamide; Pyridines; Pyrimidinones; Sinoatrial Node | 1996 |
Differential effects of MS-551 and E-4031 on action potentials and the delayed rectifier K+ current in rabbit ventricular myocytes.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Female; Male; Myocardium; Patch-Clamp Techniques; Piperidines; Pyridines; Pyrimidinones; Rabbits; Sodium-Potassium-Exchanging ATPase | 1996 |
Effects of class III antiarrhythmic drugs on the Na(+)-activated K+ channels in guinea-pig ventricular cells.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Dose-Response Relationship, Drug; Guinea Pigs; Heart Ventricles; In Vitro Techniques; Ouabain; Patch-Clamp Techniques; Piperidines; Potassium Channels; Pyridines; Pyrimidinones; Sodium | 1996 |
Effects of class I and III antiarrhythmic drugs on ventricular tachycardia-interrupting critical paced cycle length with rapid pacing.
Topics: Adolescent; Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Child; Electrophysiology; Female; Heart Conduction System; Humans; Male; Middle Aged; Piperidines; Pyridines; Pyrimidinones; Tachycardia, Ventricular | 1998 |
Comparison of electrophysiologic effects of intravenous E-4031 and MS-551, novel class III antiarrhythmic agents, in patients with ventricular tachyarrhythmias.
Topics: Adult; Aged; Anti-Arrhythmia Agents; Dose-Response Relationship, Drug; Drug Administration Schedule; Electrocardiography; Female; Heart Ventricles; Humans; Infusions, Intravenous; Male; Middle Aged; Piperidines; Pyridines; Pyrimidinones; Tachycardia, Ventricular; Treatment Outcome | 1998 |
Development of recombinant cell line co-expressing mutated Nav1.5, Kir2.1, and hERG for the safety assay of drug candidates.
Topics: Action Potentials; Biological Assay; Cell Line; Cisapride; Drug Evaluation, Preclinical; Ether-A-Go-Go Potassium Channels; HEK293 Cells; High-Throughput Screening Assays; Humans; NAV1.5 Voltage-Gated Sodium Channel; Patch-Clamp Techniques; Piperidines; Potassium Channel Blockers; Potassium Channels, Inwardly Rectifying; Pyridines; Pyrimidinones; Sodium Channels; Terfenadine; Transfection; Verapamil | 2012 |