e 4031 has been researched along with nifedipine in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 7 (50.00) | 29.6817 |
| 2010's | 5 (35.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Keserü, GM | 1 |
| Du, LP; Li, MY; Tsai, KC; Xia, L; You, QD | 1 |
| Nagashima, R; Nishikawa, T; Tobita, M | 1 |
| Jia, L; Sun, H | 1 |
| Sen, S; Sinha, N | 1 |
| Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B | 1 |
| Bouman, LN; Bourier, J; van Ginneken, AC; Verheijck, EE | 1 |
| Iost, N; Opincariu, M; Papp, JG; Szécsi, J; Varró, A; Virág, L | 1 |
| Pan, YP; Wang, XL; Xu, XH | 1 |
| Abe, J; Hamada, Y; Harada, T; Hashimoto, K; Horii, I; Sawada, Y; Shiotani, M | 1 |
| Cheng, H; Hancox, JC; Orchard, CH; Smith, GL | 1 |
| Bauriedl, J; Bussek, A; Lohmann, H; Ravens, U; Schmidt, M; Wettwer, E | 1 |
| Dahlenborg, K; Kunze, A; Sartipy, P; Steel, D; Svedhem, S | 1 |
| Bai, S; Cao, H; Dong, H; Jiang, J; Ma, Y; Pei, F; Tian, L; Yang, C; Zhao, Y | 1 |
14 other study(ies) available for e 4031 and nifedipine
| Article | Year |
|---|---|
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship | 2003 |
The pharmacophore hypotheses of I(Kr) potassium channel blockers: novel class III antiarrhythmic agents.
Topics: Anti-Arrhythmia Agents; Models, Biological; Models, Molecular; Potassium Channel Blockers; Potassium Channels; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2004 |
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated | 2005 |
Support vector machines classification of hERG liabilities based on atom types.
Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve | 2008 |
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.
Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers | 2012 |
Effects of delayed rectifier current blockade by E-4031 on impulse generation in single sinoatrial nodal myocytes of the rabbit.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Calcium; Diastole; Electrophysiology; Female; In Vitro Techniques; Male; Membrane Potentials; Nifedipine; Patch-Clamp Techniques; Piperidines; Pyridines; Rabbits; Sinoatrial Node | 1995 |
Delayed rectifier potassium current in undiseased human ventricular myocytes.
Topics: Action Potentials; Adult; Anti-Arrhythmia Agents; Barium Compounds; Cadmium; Calcium Channel Blockers; Chlorides; Female; Humans; Male; Middle Aged; Myocardium; Nifedipine; Patch-Clamp Techniques; Piperidines; Pyridines; Signal Processing, Computer-Assisted; Sodium-Potassium-Exchanging ATPase | 1998 |
[High throughput screening method of potassium channel regulators].
Topics: 4-Aminopyridine; Animals; Barbiturates; Calcium Channel Blockers; Cromakalim; Isoxazoles; Membrane Potentials; Nifedipine; Patch-Clamp Techniques; PC12 Cells; Piperidines; Potassium Channel Blockers; Potassium Channels; Pyridines; Quinidine; Rats | 2004 |
Practical application of guinea pig telemetry system for QT evaluation.
Topics: Animals; Anti-Arrhythmia Agents; Antipsychotic Agents; Bepridil; Cisapride; Disease Models, Animal; Electrocardiography; Guinea Pigs; Haloperidol; Heart; Humans; Injections, Intravenous; Long QT Syndrome; Male; Nifedipine; Pimozide; Piperidines; Pyridines; Quinidine; Reproducibility of Results; Telemetry; Terfenadine; Thioridazine | 2005 |
Acidosis inhibits spontaneous activity and membrane currents in myocytes isolated from the rabbit atrioventricular node.
Topics: Acidosis; Animals; Atrioventricular Node; Calcium Channels, L-Type; Electrophysiology; Hydrogen-Ion Concentration; Ions; Male; Myocytes, Cardiac; Nifedipine; Patch-Clamp Techniques; Piperidines; Pyridines; Rabbits; Sensitivity and Specificity; Temperature | 2009 |
Cardiac tissue slices with prolonged survival for in vitro drug safety screening.
Topics: 4-Aminopyridine; Action Potentials; Animal Testing Alternatives; Animals; Animals, Laboratory; Anti-Arrhythmia Agents; Calcium Channel Blockers; Carbenoxolone; Disease Models, Animal; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Guinea Pigs; Heart Ventricles; In Vitro Techniques; Male; Nifedipine; Piperidines; Potassium Channel Blockers; Pyridines; Rats; Rats, Wistar; Risk Assessment; Toxicity Tests | 2012 |
Non-Invasive Acoustical sensing of Drug-Induced Effects on the Contractile Machinery of Human Cardiomyocyte Clusters.
Topics: Biosensing Techniques; Cell Line; Cytochalasin D; Humans; Isoproterenol; Myocytes, Cardiac; Nifedipine; Piperidines; Pyridines; Quartz Crystal Microbalance Techniques | 2015 |
Chemical-defined and albumin-free generation of human atrial and ventricular myocytes from human pluripotent stem cells.
Topics: Action Potentials; Antioxidants; Cell Culture Techniques; Cell Differentiation; Cell Line; COUP Transcription Factor II; Culture Media; Homeodomain Proteins; Humans; Induced Pluripotent Stem Cells; Microscopy, Fluorescence; Myocytes, Cardiac; Nifedipine; Patch-Clamp Techniques; Piperidines; Pluripotent Stem Cells; Pyridines; Tretinoin | 2017 |