e 4031 has been researched along with clofilium in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gessner, G; Heinemann, SH | 1 |
| Du, LP; Li, MY; Tsai, KC; Xia, L; You, QD | 1 |
| Sen, S; Sinha, N | 1 |
| Brunden, MN; Buchanan, LV; Gibson, JK; Kabell, G | 1 |
| Bril, A; Faivre, JF; Forest, MC; Gout, B | 1 |
| de Groot, MJ; Helliwell, R; Leishman, D; Mitcheson, J; Perry, M; Sanguinetti, MC; Tristani-Firouzi, M | 1 |
6 other study(ies) available for e 4031 and clofilium
| Article | Year |
|---|---|
Inhibition of hEAG1 and hERG1 potassium channels by clofilium and its tertiary analogue LY97241.
Topics: Animals; Cell Line; Cricetinae; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Female; Humans; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quaternary Ammonium Compounds; Xenopus | 2003 |
The pharmacophore hypotheses of I(Kr) potassium channel blockers: novel class III antiarrhythmic agents.
Topics: Anti-Arrhythmia Agents; Models, Biological; Models, Molecular; Potassium Channel Blockers; Potassium Channels; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2004 |
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
Comparative assessment of ibutilide, D-sotalol, clofilium, E-4031, and UK-68,798 in a rabbit model of proarrhythmia.
Topics: Animals; Anti-Arrhythmia Agents; Blood Pressure; Electrocardiography; Heart Conduction System; Heart Rate; Male; Methoxamine; Phenethylamines; Piperidines; Pyridines; Quaternary Ammonium Compounds; Rabbits; Software; Sotalol; Sulfonamides; Torsades de Pointes | 1993 |
Electrophysiological characterization of BRL-32872 in canine Purkinje fiber and ventricular muscle. Effect on early after-depolarizations and repolarization dispersion.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Benzamides; Dogs; Electrophysiology; Female; Heart; Heart Ventricles; In Vitro Techniques; Kinetics; Male; Piperidines; Potassium Channel Blockers; Purkinje Fibers; Pyridines; Quaternary Ammonium Compounds | 1999 |
Structural determinants of HERG channel block by clofilium and ibutilide.
Topics: Amino Acid Substitution; Animals; Anti-Arrhythmia Agents; Aspartic Acid; Benzopyrans; Binding Sites; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Oocytes; Phenethylamines; Phenylalanine; Piperidines; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Pyridines; Quaternary Ammonium Compounds; Serine; Sulfonamides; Tyrosine; Xenopus laevis | 2004 |