dysidiolide and butenolide

dysidiolide has been researched along with butenolide* in 1 studies

Other Studies

1 other study(ies) available for dysidiolide and butenolide

Article	Year
Synthesis of novel antitumoural analogues of dysidiolide from ent-halimic acid. Bioorganic & medicinal chemistry, 2007, Sep-01, Volume: 15, Issue:17 Several sesterterpenolides analogues of dysidiolide have been synthesized and their in vitro antitumoural activity against human HeLa, A549, HT-29 and HL-60 carcinoma cells is presented. The proliferation inhibition data showed a significant antitumour activity of the compounds 1b, 2a, 2b, 3a, 3b, 4a, 4b, 5, inhibiting proliferation of distinct cancer cell types with an IC(50) in the low micromolar range. Topics: 4-Butyrolactone; Aldehydes; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Humans; Hydroxylation; Ketones; Models, Molecular; Molecular Structure; Sesterterpenes; Stereoisomerism; Structure-Activity Relationship; Terpenes	2007

Article

Year

Synthesis of novel antitumoural analogues of dysidiolide from ent-halimic acid.

Bioorganic & medicinal chemistry, 2007, Sep-01, Volume: 15, Issue:17

Several sesterterpenolides analogues of dysidiolide have been synthesized and their in vitro antitumoural activity against human HeLa, A549, HT-29 and HL-60 carcinoma cells is presented. The proliferation inhibition data showed a significant antitumour activity of the compounds 1b, 2a, 2b, 3a, 3b, 4a, 4b, 5, inhibiting proliferation of distinct cancer cell types with an IC(50) in the low micromolar range.

Topics: 4-Butyrolactone; Aldehydes; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Humans; Hydroxylation; Ketones; Models, Molecular; Molecular Structure; Sesterterpenes; Stereoisomerism; Structure-Activity Relationship; Terpenes

2007