dysibetaine and hexamethylsilazane

dysibetaine has been researched along with hexamethylsilazane* in 1 studies

Other Studies

1 other study(ies) available for dysibetaine and hexamethylsilazane

Article	Year
An Ugi reaction in the total synthesis of (-)-dysibetaine. Angewandte Chemie (International ed. in English), 2009, Volume: 48, Issue:10 (-)-Dysibetaine has been synthesized in 11 steps from readily available L-malic acid (see scheme). The key step is a unique Ugi 4-center-3-component cyclization reaction, where an ester group acts as the carboxylic acid component. The use of 1,1,1,3,3,3-hexamethyldisilazane as an ammonia equivalent and a specially designed isocyanide leads to an expeditious synthesis. Topics: Cyanides; Cyclization; Malates; Organosilicon Compounds; Pyrrolidinones; Stereoisomerism	2009

Article

Year

An Ugi reaction in the total synthesis of (-)-dysibetaine.

Angewandte Chemie (International ed. in English), 2009, Volume: 48, Issue:10

(-)-Dysibetaine has been synthesized in 11 steps from readily available L-malic acid (see scheme). The key step is a unique Ugi 4-center-3-component cyclization reaction, where an ester group acts as the carboxylic acid component. The use of 1,1,1,3,3,3-hexamethyldisilazane as an ammonia equivalent and a specially designed isocyanide leads to an expeditious synthesis.

Topics: Cyanides; Cyclization; Malates; Organosilicon Compounds; Pyrrolidinones; Stereoisomerism

2009